Displaying all 3 targets
Serine/threonine-protein kinase Chk2
Matched Polypeptides specific function: … controls the transcription of pro-apoptotic genes through phosphorylation of the transcription factor E2F1 …
Cyclin-dependent kinase 2
Matched Polypeptides specific function: … Phosphorylation of RB1 disturbs its interaction with E2F1. …
NAD-dependent protein deacetylase sirtuin-1
Matched Polypeptides specific function: … Inhibits E2F1 transcriptional activity and apoptotic function, possibly by deacetylation. …
Displaying all 3 targets