Displaying all 6 targets
Serine/threonine-protein kinase LATS1
Matched Polypeptides name: … Serine/threonine-protein kinase LATS1 …
Matched Polypeptides general function: … STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1 ... Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to regulate cellular genes …
Matched Name: … Serine/threonine-protein kinase LATS1 …
Matched Polypeptides general function: … STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1 ... Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to regulate cellular genes …
Matched Name: … Serine/threonine-protein kinase LATS1 …
MAP/microtubule affinity-regulating kinase 3
Matched Polypeptides general function: … Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. ... Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714). …
NUAK family SNF1-like kinase 2
Matched Polypeptides general function: … Able to phosphorylate 'Ser-464' of LATS1. …
NUAK family SNF1-like kinase 1
Matched Polypeptides general function: … Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. ... a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1 …
Cyclin-dependent kinase 1
Matched Polypeptides specific function: … /GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1 …
Serine/threonine-protein kinase 3
Matched Polypeptides general function: … STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1 …
Displaying all 6 targets