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Displaying all 3 targets
Matched Polypeptides name: … Wee1-like protein kinase …
Matched Name: … Wee1-like protein kinase …
Matched Polypeptides specific function: … /MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1 ... mitotic cell cycle by phosphorylating CCNB1, CDC25C, FOXM1, CENPU, PKMYT1/MYT1, PPP1R12A/MYPT1 and WEE1 ... activation of CDK1 by phosphorylating the positive regulator CDC25C and inhibiting the negative regulators WEE1
Matched Polypeptides specific function: … Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and ... Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1
Displaying all 3 targets