Prescribing azithromycin.
Article Details
- CitationCopy to clipboard
McMullan BJ, Mostaghim M
Prescribing azithromycin.
Aust Prescr. 2015 Jun;38(3):87-9. Epub 2015 Jun 1.
- PubMed ID
- 26648627 [ View in PubMed]
- Abstract
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and excellent tissue penetration. It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used in preference to other macrolides for some sexually transmitted and enteric infections. Azithromycin has additional immunomodulatory effects and has been used in chronic respiratory inflammatory diseases for this purpose. Potential major adverse effects include cardiovascular arrhythmias and hearing loss. Macrolide resistance is also a problem, as are interactions with commonly prescribed drugs.
DrugBank Data that Cites this Article
- Drugs
- Drug Transporters
Drug Transporter Kind Organism Pharmacological Action Actions Azithromycin P-glycoprotein 1 Protein Humans UnknownSubstrateInhibitorDetails - Drug Interactions
Drugs Interaction Integrate drug-drug
interactions in your softwareDigoxinAzithromycin The serum concentration of Digoxin can be increased when it is combined with Azithromycin. DigoxinRoxithromycin The serum concentration of Digoxin can be increased when it is combined with Roxithromycin. DigoxinSirolimus The serum concentration of Digoxin can be increased when it is combined with Sirolimus. DigoxinDirithromycin The serum concentration of Digoxin can be increased when it is combined with Dirithromycin. DigoxinTelithromycin The serum concentration of Digoxin can be increased when it is combined with Telithromycin.