Protease inhibitors: current status and future prospects.

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Leung D, Abbenante G, Fairlie DP

Protease inhibitors: current status and future prospects.

J Med Chem. 2000 Feb 10;43(3):305-41.

PubMed ID

10669559 [ View in PubMed

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Abstract

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DrugBank Data that Cites this Article

Binding Properties

Drug	Target	Property	Measurement	pH	Temperature (°C)
Benazepril	Angiotensin-converting enzyme	IC 50 (nM)	1.7	N/A	N/A	Details
Captopril	Angiotensin-converting enzyme	IC 50 (nM)	23	N/A	N/A	Details
CTS-1027	Collagenase 3	Ki (nM)	0.52	N/A	N/A	Details
Enalapril	Angiotensin-converting enzyme	IC 50 (nM)	4.5	N/A	N/A	Details
Lisinopril	Angiotensin-converting enzyme	IC 50 (nM)	4.7	N/A	N/A	Details
Moexipril	Angiotensin-converting enzyme	IC 50 (nM)	2.6	N/A	N/A	Details
Quinapril	Angiotensin-converting enzyme	IC 50 (nM)	8.3	N/A	N/A	Details
Ramipril	Angiotensin-converting enzyme	IC 50 (nM)	4	N/A	N/A	Details
Trandolapril	Angiotensin-converting enzyme	IC 50 (nM)	0.93	N/A	N/A	Details