| DB00055 | Drotrecogin alfa | approved, investigational, withdrawn | yes | multitarget | Details |
| DB00100 | Coagulation Factor IX (Recombinant) | approved, investigational | yes | cofactor | Details |
| DB06050 | TB-402 | investigational | unknown | | Details |
| DB13152 | Coagulation Factor IX Human | approved | yes | cofactor | Details |
| DB09130 | Copper | approved, investigational | no | binder | Details |
| DB13151 | Anti-inhibitor coagulant complex | approved, investigational | yes | agonist | Details |
| DB13151 | Anti-inhibitor coagulant complex | approved, investigational | yes | substrate | Details |
| DB13933 | Nonacog beta pegol | approved, investigational | yes | cofactor | Details |
| DB12872 | Vonicog alfa | approved, investigational | yes | stabilization | Details |
| DB13133 | Von Willebrand factor human | approved, investigational | yes | stabilization | Details |
| DB11572 | Thrombin alfa | approved | yes | activator | Details |
| DB11571 | Human thrombin | approved | yes | activator | Details |
| DB11300 | Thrombin | approved, investigational | yes | activator | Details |
| DB13884 | Albutrepenonacog alfa | approved | no | substrate | Details |
| DB14700 | Damoctocog alfa pegol | approved, investigational | yes | binder | Details |
| DB11312 | Protein C | approved | yes | inactivator | Details |