Sodium/potassium-transporting ATPase subunit gamma

BE0000229ProteinHumansFXYD2

May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase. It is acted on by 4 drugs in DrugBank.

Gene name
FXYD2
UniProtKB entry
P54710Swiss-Prot
Cellular location
Membrane
Residues / weight
66 residues · 7,283 Da
Also known as
ATP1C · ATP1G1 · FXYD domain-containing ion transport regulator 2 · Na(+)/K(+) ATPase subunit gamma · Sodium pump gamma chain

Resolves to

Protein
UniProtP54710UniProt nameATNG_HUMAN
Gene
HGNCHGNC:4026NCBI Gene486GenBank1575004GeneCardsFXYD2
Pharmacology
KEGGhsa:486
Structure
PDB2MKVPDB7E1ZPDB7E20
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium/potassium-transporting ATPase subunit gamma, how selective are they, and which programs against it are still in active trials?

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