Rubidium chloride Rb-82 is a radiopharmaceutical diagnostic agent used for Positron Emission Tomography (PET) imaging of the myocardium to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease. Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride.
- Mechanism
- Curator reviewed
Rb-82 is analogous to potassium ion (K+) in its biochemical behavior and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. The intracellular uptake of Rb-82 requires maintenance of ionic gradient across cell membranes. Rb-82 radioactivity is increased in viable myocardium reflecting intracellular retention, while the tracer is cleared rapidly from necrotic or infarcted tissue.
- Primary indication
- Rubidium Rb 82 chloride injection is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary...Curator reviewed · 1 structured indication
- Formula / weight
- Rb · 81.9177 g/mol (avg)
- First approval
- United States, 1989
- Also known as
- Rubidium-82
- Brand names
Resolves to
NCCSSGKUIKYAJD-OIOBTWANSA-NSMILES[82Rb+]What you can answer from here — as of September 23, 2026
Which other approved drugs treat the same conditions as Rubidium chloride Rb-82, and which companies have late-stage candidates in those indications?
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