Glutamate receptor ionotropic, NMDA 3A

BE0000641ProteinHumansGRIN3A

Component of a non-conventional N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with low calcium permeability and low voltage-dependent block by Mg(2+) (By similarity). It is acted on by 14 drugs in DrugBank.

Gene name
GRIN3A
UniProtKB entry
Q8TCU5Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,115 residues · 125,464 Da
Also known as
GluN3A · KIAA1973 · N-methyl-D-aspartate receptor subtype 3A · NMDAR-L · NMDAR3A

Resolves to

Protein
UniProtQ8TCU5UniProt nameNMD3A_HUMAN
Gene
HGNCHGNC:16767NCBI Gene116443GenBank20372905GeneCardsGRIN3A
Pharmacology
KEGGhsa:116443
Structure
PDB8USWPDB8USXPDB8UUE
Drugs

What you can answer from here — as of September 07, 2019

14DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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19GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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35+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutamate receptor ionotropic, NMDA 3A, how selective are they, and which programs against it are still in active trials?

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