| DB00392 | Profenamine | approved | yes | antagonist | Details |
| DB01221 | Ketamine | approved, vet_approved | yes | antagonist | Details |
| DB00514 | Dextromethorphan | approved | yes | antagonist | Details |
| DB00721 | Procaine | approved, investigational, vet_approved | yes | antagonist | Details |
| DB00898 | Ethanol | approved | yes | antagonist | Details |
| DB01173 | Orphenadrine | approved | yes | antagonist | Details |
| DB03575 | Phencyclidine | illicit | yes | antagonist | Details |
| DB00142 | Glutamic acid | approved, nutraceutical | unknown | | Details |
| DB01520 | Tenocyclidine | experimental, illicit, investigational | yes | antagonist | Details |
| DB01549 | Rolicyclidine | experimental, illicit | yes | | Details |
| DB04926 | Neramexane | investigational | unknown | | Details |
| DB01159 | Halothane | approved, vet_approved | unknown | antagonist | Details |
| DB00915 | Amantadine | approved | yes | antagonist | Details |
| DB06151 | Acetylcysteine | approved, investigational | unknown | activator | Details |