ATP-sensitive inward rectifier potassium channel 1

BE0000644ProteinHumansKCNJ1

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. It is acted on by 9 drugs in DrugBank.

Gene name
KCNJ1
UniProtKB entry
P48048Swiss-Prot
Cellular location
Cell membrane
Residues / weight
391 residues · 44,795 Da
Also known as
ATP-regulated potassium channel ROM-K · Inward rectifier K(+) channel Kir1.1 · Potassium channel, inwardly rectifying subfamily J member 1 · ROMK1

Resolves to

Protein
UniProtP48048UniProt nameKCNJ1_HUMAN
Gene
HGNCHGNC:6255NCBI Gene3758GenBank529313GeneCardsKCNJ1
Pharmacology
IUPHAR/GtoPdb429KEGGhsa:3758
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP-sensitive inward rectifier potassium channel 1, how selective are they, and which programs against it are still in active trials?

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