Low affinity immunoglobulin gamma Fc region receptor III-B

BE0000901ProteinHumansFCGR3B

Receptor for the Fc region of immunoglobulins gamma. It is acted on by 13 drugs in DrugBank.

Gene name
FCGR3B
UniProtKB entry
O75015Swiss-Prot
Cellular location
Cell membrane
Residues / weight
233 residues · 26,243 Da
Also known as
CD16-I · CD16B · Fc-gamma RIII · Fc-gamma RIII-beta · Fc-gamma RIIIb

Resolves to

Protein
UniProtO75015UniProt nameFCG3B_HUMAN
Gene
HGNCHGNC:3620NCBI Gene2215GenBank31322GeneCardsFCGR3B
Pharmacology
KEGGhsa:2215
Structure
PDB1E4JPDB1E4KPDB1FNL
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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38+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Low affinity immunoglobulin gamma Fc region receptor III-B, how selective are they, and which programs against it are still in active trials?

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