Tubulin beta-4B chain

BE0001367ProteinHumansTUBB4B

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. It is acted on by 7 drugs in DrugBank.

Gene name
TUBB4B
UniProtKB entry
P68371Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
445 residues · 49,831 Da
Also known as
TUBB2C · Tubulin beta-2 chain · Tubulin beta-2C chain

Resolves to

Protein
UniProtP68371UniProt nameTBB4B_HUMAN
Gene
HGNCHGNC:20771NCBI Gene10383GenBank37494GeneCardsTUBB4B
Pharmacology
KEGGhsa:10383
Structure
PDB7UN1PDB7UNGPDB8J07
Drugs

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tubulin beta-4B chain, how selective are they, and which programs against it are still in active trials?

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