Tryptophan biosynthesis protein TrpCF

BE0001558ProteinEscherichia coli (strain K12)trpC

Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. It is acted on by 1 drug in DrugBank.

Gene name
trpC
UniProtKB entry
P00909Swiss-Prot
Residues / weight
453 residues · 49,492 Da
Also known as
trpF

Resolves to

Protein
UniProtP00909UniProt nameTRPC_ECOLI
Gene
NCBI Gene945519GenBank43192
Pharmacology
KEGGecj:JW1254
Structure
PDB1JCMPDB1PIIPDB2KZH
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tryptophan biosynthesis protein TrpCF, and which indications are they being tested in?

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