Proteasome subunit beta type-3

BE0003917ProteinHumansPSMB3

Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. It is acted on by 4 drugs in DrugBank.

Gene name
PSMB3
UniProtKB entry
P49720Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
205 residues · 22,949 Da
Also known as
beta-3 · Proteasome chain 13 · Proteasome component C10-II · Proteasome subunit beta-3 · Proteasome theta chain

Resolves to

Protein
UniProtP49720UniProt namePSB3_HUMAN
Gene
HGNCHGNC:9540NCBI Gene5691GenBank565647GeneCardsPSMB3
Pharmacology
KEGGhsa:5691
Structure
PDB4R3OPDB4R67PDB5A0Q
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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29GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit beta type-3, and which indications are they being tested in?

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