Name
Esterases
Accession Number
DBCAT000190
Description

Not Available

Drugs
DrugDrug Description
Dornase alfaA synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
IdursulfaseA purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients.
GalsulfaseA recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme.
RanpirnaseFor the treatment of various forms of cancer.
ALTU-135Investigated for use/treatment in cystic fibrosis and pancreatic disorders.
Alkaline PhosphataseInvestigated for use/treatment in ulcerative colitis.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Asfotase alfaAn enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP).
Sebelipase alfaA recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency.
Olipudase alfaOlipudase alfa has been used in trials studying the treatment of Sphingomyelin Lipidosis and Human Acid Sphingomyelinase Deficiency.
Pancrelipase lipaseA lipase used to treat pancreatic exocrine insufficiency.
DesoxyribonucleaseDesoxyribonuclease is a crystalline enzyme that aids in the digestion of the thymus nucleic acid. The mechanism of action of the enzyme involves the splitting of thymus nucleic acid into...
Deoxyribonuclease IDeoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7 . It is normally found in saliva, urine, pancreatic secretions, and blood . Because of...
Drugs & Drug Targets
DrugTargetType
Dornase alfaDNAtarget
PancrelipaseDietary fattarget
PancrelipaseDietary proteintarget
PancrelipaseDietary starchtarget
IdursulfasePerilipin-3target
IdursulfaseDermatan sulfatetarget
IdursulfaseHeparan sulfatetarget
GalsulfasePerilipin-3target
GalsulfaseDermatan sulfatetarget
RanpirnaseDNAtarget
Asfotase alfaPyrophosphatetarget
Pancrelipase lipaseDietary fattarget