Polyamines
- Name
- Polyamines
- Accession Number
- DBCAT000281
- Description
Amine compounds that consist of carbon chains or rings containing two or more primary amino groups.
- Drugs
Drug Drug Description Indium In-111 satumomab pendetide For diagnosis of extrahepatic malignant cancers Spermine For nutritional supplementation, also for treating dietary shortage or imbalance Gadodiamide A gadolinium-based contrast agent used for the visualization of lesions with vascularity during magnetic resonance imaging (MRI) scans. Ethambutol An antituberculosis agent used in the prophylaxis and treatment of tuberculosis (TB). Colestipol A bile acid sequestrant used as an adjunct to diet and exercise to reduce LDL-C cholesterol levels in patients with primary hypercholesterolemia. Sevelamer A phosphate binder used to treat hyperphosphatemia. Gadopentetic acid A gadolinium compound used as a contrast agent in MRIs. Tripelennamine A histamine H1 antagonist used to treat hypersensitivity reactions, coughs, and the common cold. Edetic acid A chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Putrescine Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more... 4,5-Dimethyl-1,2-phenylenediamine Not Available Hexamethylene diamine Not Available Glutathionylspermidine Not Available Trypanothione Not Available Spermidine Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and... Octamethylenediamine Not Available Methapyrilene Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. Ezogabine An antiepileptic agent used as an adjuvant treatment of partial-onset seizures. SQ-109 Investigated for use/treatment in bacterial infection, infectious and parasitic disease (unspecified), and tuberculosis. REP8839 For the treatment of bacterial infections caused by susceptible microorganisms (Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), and Streptococcus pyogenes). DP-b99 Investigated for use/treatment in strokes and traumatic brain injuries. Trodusquemine Investigated for use/treatment in obesity and diabetes mellitus type 2. Diethylnorspermine Investigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer. Mangafodipir An organ-specific paramagnetic contrast agent indicated for the imaging of the hepatobiliary system and detecting lesions in the liver and pancreas. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Triethylenetetramine A copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate. Chloropyramine For the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Gadoxetic acid A gadolinium-based contrast agent used in magnetic resonance imaging (MRI) to help characterize lesions in the liver. Afuresertib Afuresertib has been used in trials studying the treatment of Cancer and Neoplasms, Haematologic. Uprosertib Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others. Pentetreotide A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours. Olaflur A fluoride treatment for patients at risk of dental caries, sensitive teeth, or enamel decalcification. Sodium feredetate Not Annotated Tenitramine Not Annotated Pentetic acid DTPA is widely used in industry and medicine. As a medical agent, it is approved for its use in medical imaging and for the decorporation of internally deposited radionuclides. It... p-Phenylenediamine Not Annotated Ethylenediamine Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... N,N'-diphenyl-1,4-phenylenediamine Not Annotated 4-(Isopropylamino)diphenylamine 4-(Isopropylamino)diphenylamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... Quaternium-15 Quaternium-15 is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years... Cadaverine Cadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine. MDL72527 Not Available Gallium Ga-68 gozetotide A radiopharmaceutical agent used in the diagnosis of prostate-specific membrane antigen (PSMA) positive lesions in male patients during positron emission tomography. Chiauranib Chiauranib is under investigation in clinical trial NCT03974243 (Chiauranib in Combination With Chidamide in Patients With Relapsed/refractory Non-hodgkin's Lymphoma). Acetyldinaline Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma). CGC-11047 Investigated for use/treatment in lymphoma (unspecified), macular degeneration, prostate cancer, and solid tumors. - Drugs & Drug Targets