- Accession Number
Compounds that are derived from PIPERAZINE
Drug Drug Description Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Pipobroman For the treatment of polycythaemia vera and refractory chronic myeloid leukaemia. Ranolazine An anti-anginal drug used for the treatment of chronic angina. Cetirizine A selective Histamine-1 antagonist drug used in allergic rhinitis and chronic urticaria. Thiethylperazine A drug used for the treatment of nausea and vomiting. Eszopiclone A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Buspirone An anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression. Hydroxyzine An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria. Cinnarizine A drug used for the management of labyrinthine disorder symptoms, including vertigo, tinnitus, nystagmus, nausea, and vomiting. Imatinib A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. Trazodone A serotonin uptake inhibitor used to treat major depressive disorder. Delavirdine A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. Meclizine A histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness. Vardenafil A phosphodiesterase 5 inhibitor used to treat erectile dysfunction. Flupentixol A thioxanthene neuroleptic used to treat schizophrenia and depression. Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. Itraconazole An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. Cyclizine An antihistamine and antiemetic drug used for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness, and vertigo. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. Pipecuronium A nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures. Almitrine For the treatment of chronic obstructive pulmonary disease. Flunarizine A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. Prasugrel A P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI. Levocetirizine An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Trimetazidine A piperazine derivative indicated as an adjunct therapy in symptomatic treatment of stable angina pectoris. Piribedil A dopamine agonist used with or without levodopa in the treatment of Parkinson's disease. Lidoflazine Not Annotated Piperazine A medication used to treat roundworm and pinworm. Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). Diethylcarbamazine An anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa. 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Dexrazoxane A cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. Hydroxyfasudil Not Available Plinabulin Investigated for use/treatment in cancer/tumors (unspecified). Aplaviroc Investigated for use/treatment in HIV infection. Fasudil Fasudil has been investigated in Carotid Stenosis. Etoperidone Etoperidone has been studied for the treatment of depression , tremors in Parkinson, extrapyramidal symptoms and male impotence . It is not certain if it was ever approved and marketed... Cabotegravir An HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV-1 infection. Epelsiban Epelsiban has been investigated for the treatment of Premature Ejaculation. Aripiprazole lauroxil An antipsychotic used to treat schizophrenia in adults. NNZ-2591 NNZ-2591 (cyclo-L-glycyl-L-2-allylproline) is an investigational synthetic analog of cyclic glycine-proline (cGP), a breakdown product of human insulin-like growth factor 1 (IGF-1), that has been chemically modified to increase its half-life,... Homochlorcyclizine Not Annotated Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
- Drugs & Drug Targets