- Accession Number
Agents that promote the excretion of urine through their effects on kidney function.
- ATC Classification
Drug Drug Description Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Triamterene A potassium-sparing diuretic used in the treatment of edema and in the management of hypertension. Spironolactone An aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia. Amiloride A pyrizine compound used to treat hypertension and congestive heart failure. Eplerenone An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. Quinethazone Used to treat hypertension. Piretanide A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. Tienilic acid For the treatment of hypertension. Canrenoic acid An aldosterone antagonist used in primary hyperaldosteronism and other disorders related to aberrant aldosterone levels. Canrenone An antimineralocorticoid and active metabolite of spironolactone used in the treatment of primary hyperaldosteronism and edematous states caused by secondary hyperaldosteronism (e.g. heart failure). Cicletanine Cicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension. Mefruside Not Annotated Cyclopenthiazide Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... Fenquizone Not Annotated Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Muzolimine Not Annotated Xipamide A diuretic indicated in the treatment of edema. Methyclothiazide A diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy. Cyclothiazide Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either... Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Trichlormethiazide Used in the treatment of oedema (including that associated with heart failure) and hypertension. Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Metolazone A thiazide-like diuretic used to treat hypertension. Methazolamide A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. Mannitol A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Acetazolamide A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. Chlorothiazide A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. Ularitide Investigated for use/treatment in congestive heart failure. Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Potassium citrate An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. Efonidipine For the treatment of hypertension. Isosorbide A vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. It was previously used to reduce intraocular pressure. Rolofylline Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure. Spiradoline Spiradoline has been investigated for the basic science of Bipolar Depression. Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Conivaptan An antidiuretic hormone inhibitor used to raise serum sodium levels. Potassium cation Potassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions. Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Tolvaptan A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia. Mersalyl Elevated blood pressure, edema [L1577, L1585]. Meticrane Meticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure . Mebutizide Not Annotated Clorexolone Not Annotated Clofenamide Not Annotated Epitizide Epitizide is an agent, commonly found in combination triamterene, used to produce diuresis. Bromotheophylline Bromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with... Benzthiazide For the treatment of high blood pressure and management of edema. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Dapagliflozin A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. Canagliflozin A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. Potassium A medication used to treat hypokalemic conditions and to clear the colon prior to colonoscopy. Ertugliflozin A SGLT2 inhibitor used to treat type 2 diabetes mellitus. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Indisulam Investigated for use/treatment in lung cancer. Buthiazide A diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases. Empagliflozin An SGLT2 inhibitor used to manage type 2 diabetes mellitus. Tripamide Not Annotated Finerenone A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes. Bexagliflozin A sodium-glucose co-transporter 2 inhibitor used to improve glycemic control in patients with type 2 diabetes mellitus. Ipragliflozin Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. Luseogliflozin An SGLT2 inhibitor used to manage type 2 diabetes mellitus. Sotagliflozin An orally administered dual SGLT1/2 inhibitor used alongside insulin to improve glycemic control in patients with type 1 diabetes mellitus. Anaritide Not Annotated
- Drugs & Drug Targets