Voltage-Gated Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
- Accession Number
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
Drug Drug Description Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. Disopyramide A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Oxcarbazepine An anti-epileptic used in the treatment of partial-onset seizures. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. Flecainide A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Ajmaline An antiarrhythmic used to manage a variety of forms of tachycardias. Aprindine Aprindine is a cardiac depressant used in arrhythmias. Eslicarbazepine acetate An anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy. Eslicarbazepine An antiepileptic indicated as a monotherapy or adjunct therapy in the treatment of epilepsy. Ethotoin A hydantoin antiepileptic used to control tonic-clonic and complex partial seizures. Rufinamide An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). Lacosamide An antiepileptic drug used to treat partial onset seizures in adults. Cenobamate A small molecule drug indicated to treat partial onset seizures in adults. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Moricizine An antiarrhythmic used to treat arrhythmias. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Procainamide A medication used to treat life threatening ventricular arrhythmias. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
- Drugs & Drug Targets