Voltage-Gated Sodium Channel Blockers
- Name
- Voltage-Gated Sodium Channel Blockers
- Accession Number
- DBCAT000615
- Description
A class of drugs that inhibit the activation of VOLTAGE-GATED SODIUM CHANNELS.
- Drugs
Drug Drug Description Ajmaline An antiarrhythmic used to manage a variety of forms of tachycardias. Aprindine Aprindine is a cardiac depressant used in arrhythmias. Cenobamate A small molecule drug indicated to treat partial onset seizures in adults. Disopyramide A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. Encainide A voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects. Eslicarbazepine An antiepileptic indicated as a monotherapy or adjunct therapy in the treatment of epilepsy. Eslicarbazepine acetate An anticonvulsant agent used as an adjunct to treat partial-onset seizures in patients with inadequate clinical response to conventional antiepileptic therapy. Ethotoin A hydantoin antiepileptic used to control tonic-clonic and complex partial seizures. Flecainide A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). Lacosamide An antiepileptic drug used to treat partial-onset seizures and primary generalized tonic-clonic seizures. Lidocaine A local anesthetic used in a wide variety of superficial and invasive procedures. Mexiletine A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Moricizine An antiarrhythmic used to treat arrhythmias. Oxcarbazepine An anti-epileptic used in the treatment of partial-onset seizures. Phenytoin An anticonvulsant drug used in the prophylaxis and control of various types of seizures. Procainamide A medication used to treat life threatening ventricular arrhythmias. Propafenone A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Rufinamide An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). Suzetrigine A sodium channel blocker used to treat moderate to severe acute pain in adults. Tocainide An orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias. - Drugs & Drug Targets