Serotonin 5-HT1 Receptor Agonists
- Serotonin 5-HT1 Receptor Agonists
- Accession Number
Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes.
Drug Drug Description Zolmitriptan A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Naratriptan A 5-HT1B/1D receptor agonist used to treat migraines. Naluzotan Investigated for use/treatment in anxiety disorders and depression. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Vortioxetine An atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Almotriptan A 5-HT1B/1D receptor agonist used to treat migraines. Rizatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Frovatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Lisuride For the management of Parkinson's Disease Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Ziprasidone An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. Flibanserin A 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. Cinitapride A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying. Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia. Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. 5-methoxy-N,N-dimethyltryptamine 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,... Tetrahydrocannabivarin THCV does not currently have any FDA, Health Canada, or EMA approved indications. Piclozotan Piclozotan has been investigated for the treatment of Parkinson's Disease. Cannabidiol An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. Eletriptan A triptan used for the treatment of migraines. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
- Drugs & Drug Targets