Accession Number

A group of ISOQUINOLINES in which the nitrogen containing ring is protonated. They derive from the non-enzymatic Pictet-Spengler condensation of CATECHOLAMINES with ALDEHYDES.

DrugDrug Description
TubocurarineTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
QuinaprilAn ACE inhibitor prodrug used to treat hypertension, congestive heart failure, and slow rate of progression of renal disease.
TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
Metocurine iodideFor use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy.
MetocurineMetocurine is a muscle relaxant.
AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Drugs & Drug Targets
TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
Tubocurarine5-hydroxytryptamine receptor 3Atarget
TubocurarineSolute carrier family 22 member 1transporter
TubocurarineSolute carrier family 22 member 2transporter
TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
SolifenacinMuscarinic acetylcholine receptor M3target
SolifenacinMuscarinic acetylcholine receptor M1target
SolifenacinCytochrome P450 3A4enzyme
SolifenacinMuscarinic acetylcholine receptor M2target
SolifenacinMuscarinic acetylcholine receptor M4target
SolifenacinMuscarinic acetylcholine receptor M5target
Solifenacinalpha1-acid glycoproteincarrier
SolifenacinCytochrome P450 1A1enzyme
SolifenacinCytochrome P450 2D6enzyme
QuinaprilAngiotensin-converting enzymetarget
QuinaprilSolute carrier family 15 member 1transporter
QuinaprilSolute carrier family 15 member 2transporter
QuinaprilSolute carrier family 22 member 8transporter
QuinaprilLiver carboxylesterase 1enzyme
QuinaprilSerum albumincarrier
TrabectedinCytochrome P450 3A4enzyme
TrabectedinCytochrome P450 2C9enzyme
TrabectedinCytochrome P450 2D6enzyme
TrabectedinCytochrome P450 2E1enzyme
TrabectedinCytochrome P450 2C19enzyme
TrabectedinProstaglandin G/H synthase 1enzyme
Metocurine iodideNeuronal acetylcholine receptor subunit alpha-2target
MetocurineNeuronal acetylcholine receptor subunit alpha-2target
MetocurineMuscarinic acetylcholine receptor M2target