Triterpenes

Name
Triterpenes
Accession Number
DBCAT001474
Description

A class of terpenes (the general formula C30H48) formed by the condensation of six isoprene units, equivalent to three terpene units.

Drugs
DrugDrug Description
LanosterolNot Available
Glycyrrhizic acidGlycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to...
GinsenosidesDammarane type triterpene saponins based mainly on the aglycones, protopanaxadiol and protopanaxatriol.
IbrexafungerpA triterpene antifungal indicated in the treatment of vulvovaginal candidiasis and prevention of recurrent vulvovaginal candidiasis in post-menarchal patients.
SqualeneSqualene is originally obtained from shark liver oil. It is a natural 30-carbon isoprenoid compound and intermediate metabolite in the synthesis of cholesterol. It is not susceptible to lipid peroxidation...
CarbenoxoloneA drug used to symptomatically treat lip sores and mouth ulcers.
Bardoxolone methylInvestigated for use/treatment in lymphoma (unspecified), multiple myeloma, and solid tumors.
Ginsenoside CNot Available
Ginsenoside Rb1Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as...
Ginsenoside Rg1Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as...
SqualaneNot Annotated
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
LupeolLupeol has been investigated for the treatment of Acne.
BardoxoloneBardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce...
EnoxoloneEnoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME).
AcetoxoloneNot Annotated
Asiatic acidFrom Centella asiatica and other plants; shows a variety of bioactivities.
Ginsenoside B2Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes).
beta-EscinAn anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
EscinAn anti-inflammatory and vasoconstrictive agent indicated to treat minor muscle and joint trauma.
Birch bark extractA herbal medicinal product used to treat partial thickness wounds.
PristimerinPristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
Drugs & Drug Targets
DrugTargetType
LanosterolLanosterol synthasetarget
Glycyrrhizic acidCorticosteroid 11-beta-dehydrogenase isozyme 1target
Glycyrrhizic acidAldo-keto reductase family 1 member C4carrier
Glycyrrhizic acidAldo-keto reductase family 1 member C3carrier
Glycyrrhizic acidAldo-keto reductase family 1 member C2carrier
Glycyrrhizic acidTumor necrosis factortarget
Glycyrrhizic acidCaspase-3target
Glycyrrhizic acidNuclear factor NF-kappa-Btarget
Glycyrrhizic acidLipoprotein lipasetarget
Glycyrrhizic acidSerum albumincarrier
Glycyrrhizic acidBile salt export pumptransporter
IbrexafungerpCytochrome P450 3A4enzyme
IbrexafungerpUDP-glucuronosyltransferases (UGTs)enzyme
IbrexafungerpSulfotransferaseenzyme
IbrexafungerpCytochrome P450 2C8enzyme
IbrexafungerpP-glycoprotein 1transporter
IbrexafungerpSolute carrier organic anion transporter family member 1B3transporter
IbrexafungerpSerum albumincarrier
Ibrexafungerp1,3-beta-glucan synthase component GSC2target
IbrexafungerpGTP-binding protein RHO1target
Carbenoxolone3-alpha-(or 20-beta)-hydroxysteroid dehydrogenasetarget
CarbenoxoloneCorticosteroid 11-beta-dehydrogenase isozyme 1target
Bardoxolone methylNF-kappa-B inhibitor alphatarget
Ginsenoside Rb1Solute carrier organic anion transporter family member 1B3target
Ginsenoside Rg1Solute carrier organic anion transporter family member 1B3target
LupeolNeutrophil elastasetarget
BardoxoloneCaspase-8target
Birch bark extractCytochrome P450 2C8enzyme
Birch bark extractCytochrome P450 3A Subfamilyenzyme