Ginsenoside Rg3

DB19257InvestigationalSmall molecule

Ginsenoside Rg3 is under investigation in clinical trial NCT01757366 (Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer).

Chemical structure of Ginsenoside Rg3
Formula / weight
C42H72O13 · 785.025 g/mol (avg)
Also known as
.beta.-d-glucopyranoside, (3.beta.,12.beta.)-12,20-dihydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl- · 20(s)-ginsenoside-rg3 · 20s-ginsenoside rg3 · 3-o-.beta.-d-glucopyranosyl-(1->2)-.beta.-d-glucopyranosyldammar-24-ene-3.beta.,12.beta.,20s-triol · Ginsenoside 20-rg3

Resolves to

Structure
InChIKeyRWXIFXNRCLMQCD-JBVRGBGGSA-NSMILES[H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@@](C)(O)CCC=C(C)C

What you can answer from here — as of April 02, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
3Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Ginsenoside Rg3, and which of those have an active Phase 3 trial?

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