Antipsoriatics

Name
Antipsoriatics
Accession Number
DBCAT002154
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
AcitretinAn oral retinoid used in the treatment of severe psoriasis.
MethoxsalenA furocoumarin used to treat psoriasis and vitiligo.
TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
EtretinateFor the treatment of severe psoriasis in adults.
Fumaric AcidNot Available
CalcipotriolA topical synthetic vitamin D2 derivative used in the treatment of plaque psoriasis.
TrioxsalenA psoralen derivative that has been used in combination with UV light to treat vitiligo, but has been discontinued by its manufacturer.
AnthralinAn anthracene used to treat stable plaque psoriasis.
BergaptenBergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
TacalcitolNot Annotated
Drugs & Drug Targets
DrugTargetType
CalcitriolVitamin D3 receptortarget
Calcitriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
CalcitriolCytochrome P450 3A4enzyme
CalcitriolHomeobox protein Hox-A10target
CalcitriolVitamin D-binding proteincarrier
AcitretinRetinoic acid receptor alphatarget
AcitretinRetinoic acid receptor RXR-betatarget
AcitretinRetinoic acid receptor gammatarget
AcitretinRetinoic acid receptor betatarget
AcitretinRetinoic acid receptor RXR-gammatarget
AcitretinRetinoic acid receptor RXR-alphatarget
AcitretinSerum albumincarrier
AcitretinRetinol-binding protein 1target
AcitretinRetinoic acid receptor RXRtarget
MethoxsalenDNAtarget
MethoxsalenCytochrome P450 2A6enzyme
MethoxsalenCytochrome P450 1A2enzyme
MethoxsalenCytochrome P450 1A1enzyme
MethoxsalenCytochrome P450 2A13enzyme
TazaroteneRetinoic acid receptor alphatarget
TazaroteneRetinoic acid receptor RXR-betatarget
TazaroteneRetinoic acid receptor gammatarget
TazaroteneRetinoic acid receptor betatarget
TazaroteneCytochrome P450 2C8enzyme
EtretinateRetinoic acid receptor alphatarget
EtretinateRetinoic acid receptor RXR-betatarget
EtretinateRetinoic acid receptor gammatarget
EtretinateRetinoic acid receptor betatarget
EtretinateRetinoic acid receptor RXR-gammatarget
EtretinateRetinoic acid receptor RXR-alphatarget
EtretinateCellular retinoic acid-binding protein 1carrier
EtretinateCytochrome P450 19A1enzyme
Fumaric AcidMalate dehydrogenasetarget
Fumaric AcidFumarate reductase flavoprotein subunittarget
Fumaric AcidNAD-dependent malic enzyme, mitochondrialtarget
Fumaric AcidFumarylacetoacetasetarget
Fumaric AcidFumarate reductase flavoprotein subunittarget
CalcipotriolVitamin D3 receptortarget
CalcipotriolMyeloperoxidaseenzyme
Calcipotriol1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
TrioxsalenDNAtarget
AnthralinKeratin, type II cytoskeletal 2 epidermaltarget
AnthralinC-Jun-amino-terminal kinase-interacting protein 1target
AnthralinKeratin, type I cytoskeletal 12target