Muscle Relaxants

Name
Muscle Relaxants
Accession Number
DBCAT002178
Description

A muscle relaxant is a drug that affects skeletal muscle function and decreases the muscle tone.

Drugs
DrugDrug Description
AfloqualoneNot Annotated
AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
Arbaclofen PlacarbilInvestigated for the treatment of spasticity in multiple sclerosis, acute back spasms, and GERD.
AtracuriumA neuromuscular blocker indicated to relax muscles during mechanical ventilation under general anesthesia or intubation.
BaclofenA GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
BendazolBendazol is a small molecule drug. Bendazol has a monoisotopic molecular weight of 208.1 Da.
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
Botulinum toxin type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
CarisoprodolA centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions.
ChlormezanoneUsed in the management of anxiety and in the treatment of muscle spasm.
ChlorphenesinA phenol ether used to treat painful muscular conditions.
ChlorproethazineNot Annotated
ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
CisatracuriumA skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation.
ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
DantroleneA direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
DaxibotulinumtoxinAA botulinum toxin used to treat glabellar lines and cervical dystonia in adults.
DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
DonepezilAn acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
DoxacuriumA nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
EperisoneAn antispasmodic that functions through voltage-gated channel blockade, notably with little to no sedation, effective in relaxing skeletal muscles and vascular smooth muscles.
EszopicloneA sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
EtizolamA thienodiazepine derivative used to treat anxiety and insomnia.
Fazadinium bromideNot Annotated
FebarbamateNot Annotated
FenyramidolA muscle relaxant indicated in the symptomatic treatment of musculoskeletal pain and spasms.
FludiazepamUsed for the short-term treatment of anxiety disorders.
FlunitrazepamA benzodiazepine used to manage anxiety disorders and insomnia.
GallamineNot Annotated
GantacuriumInvestigated for use/treatment in anesthesia (unspecified).
HexafluroniumUsed as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.
HexamethoniumA nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been...
LorazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
MedazepamA long-acting benzodiazepine used for its sedative and anxiolytic properties.
MephenesinA cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis.
MephenoxaloneA muscle relaxant indicated in the treatment of painful muscle spasms and cramps.
MeprobamateAn anxiolytic drug used for the short-term management of anxiety symptoms.
MetaxaloneA muscle relaxant used to treat muscle pain or spasm.
MethaqualoneFor the treatment of insomnia, and as a sedative and muscle relaxant.
MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
MetocurineMetocurine is a muscle relaxant.
MivacuriumA short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.
NitrazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
PhenprobamateA skeletal muscle relaxant indicated in the treatment of pain caused by muscle spasms.
PipecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures.
PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
PridinolAn atropine-like muscle relaxant indicated in the treatment of muscle pain associated with muscle tightness.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
RilmakalimRilmakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Rilmakalim is a potassium channel activator, antihypertensive. Rilmakalim has a monoisotopic molecular...
RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
StyramateNot Annotated
SuccinylcholineA depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
TemazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia.
TetrazepamNot Annotated
ThiocolchicosideA semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
TolperisoneA muscle relaxant used to relieve spasticity after stroke in adults.
TubocurarineTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
VecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
XylazineA non-opioid and clonidine analog with analgesic and muscle relaxant properties used as a tranquilizer used in veterinary medicine.
Y-27632Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
ZoxazolamineNot Annotated