UGT1A1 Inhibitors

All categories

Name: UGT1A1 Inhibitors
Accession Number: DBCAT002664
Description: Not Available
Drugs: Drug Drug Description
Adenine A purine base which forms a component of DNA among other functions and is present in many multivitamins.
Almonertinib A third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) indicated for the treatment of patients with metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC).
Amitriptyline A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
Aprocitentan An endothelin receptor antagonist used for the treatment of uncontrolled hypertension in patients inadequately controlled on other treatments.
Asciminib An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Atazanavir An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Belumosudil An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
Dabrafenib A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Dacomitinib A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Dasabuvir A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Defactinib An inhibitor of FAK used alongside a MEK1/RAF inhibitor for the treatment of recurrent low-grade serous ovarian cancer.
Deferasirox An iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
Eltrombopag A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Enasidenib An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Encorafenib A kinase inhibitor used to treat unresectable or metastatic melanoma with BRAF mutations.
Erlotinib An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Ertugliflozin An SGLT2 inhibitor used to treat type 2 diabetes mellitus alone or in combination with other antidiabetic drugs.
Flunitrazepam A benzodiazepine used to manage anxiety disorders and insomnia.
Flurbiprofen An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Fostamatinib A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
Gemfibrozil A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Glecaprevir A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
Indinavir A protease inhibitor used to treat HIV infection.
Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Ketoconazole A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Lazertinib A tyrosine kinase inhibitor used in combiantion with amivantamab to treat non-small cell lung cancer with EGFR mutations.
Momelotinib A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis.
Nilotinib A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Olaparib A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Ombitasvir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Osilodrostat An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Paltusotine A somatostatin receptor agonist used to treat acromegaly in adults whose surgery is not an option or has not been effective.
Paritaprevir A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Pazopanib An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
Pexidartinib An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Pibrentasvir A Hepatitis C NS5A inhibitor used to treat Hepatitis C.
Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Propofol A medication used in general anesthesia and for sedation.
Quizartinib A FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication
Regorafenib A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
Repotrectinib A tyrosine kinase inhibitor used to treat locally active or metastatic non-small cell lung cancer
Rucaparib A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
Silibinin A flavonolignan with hepatoprotective effects used to treat toxic liver damage and as an adjunct in the management of chronic conditions such as cirrhosis and hepatitis.
Sodium aurothiomalate A disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.
Ubrogepant An oral CGRP antagonist used in the acute treatment of migraine with or without aura.
Valproic acid An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
Drugs & Drug Targets: Drug Target Type
Adenine Adenine phosphoribosyltransferase target
Adenine DNA target
Adenine S-methyl-5'-thioadenosine phosphorylase target
Adenine Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase target
Adenine Acetyl-CoA carboxylase 2 target
Adenine Low molecular weight phosphotyrosine protein phosphatase target
Adenine 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase target
Adenine Peroxisomal trans-2-enoyl-CoA reductase target
Adenine Adenine DNA glycosylase target
Adenine Nucleoside 2-deoxyribosyltransferase target
Adenine SRSF protein kinase 2 target
Adenine Holliday junction branch migration complex subunit RuvB target
Adenine UDP-glucuronosyltransferase 1A1 enzyme
Almonertinib Receptor protein-tyrosine kinase target
Almonertinib Epidermal growth factor receptor target
Almonertinib Cytochrome P450 3A4 enzyme
Almonertinib Cytochrome P450 3A5 enzyme
Almonertinib Cytochrome P450 1A2 enzyme
Almonertinib Cytochrome P450 2A6 enzyme
Almonertinib Albumin carrier
Almonertinib Alpha-1-acid glycoprotein 1 carrier
Almonertinib Solute carrier organic anion transporter family member 1B1 transporter
Almonertinib Solute carrier family 22 member 6 transporter
Almonertinib Solute carrier family 22 member 2 transporter
Almonertinib ATP-dependent translocase ABCB1 transporter
Almonertinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Almonertinib UDP-glucuronosyltransferase 1A1 enzyme
Almonertinib UDP-glucuronosyltransferase 2B7 enzyme
Almonertinib Multidrug and toxin extrusion protein 1 transporter
Almonertinib Solute carrier family 22 member 1 transporter
Amitriptyline UDP-glucuronosyltransferase 1A4 enzyme
Amitriptyline Alpha-1A adrenergic receptor target
Amitriptyline 5-hydroxytryptamine receptor 1A target
Amitriptyline 5-hydroxytryptamine receptor 2A target
Amitriptyline Histamine H1 receptor target
Amitriptyline Alpha-1-acid glycoprotein 1 carrier
Amitriptyline Albumin carrier
Amitriptyline Cytochrome P450 2D6 enzyme
Amitriptyline Cytochrome P450 2C19 enzyme
Amitriptyline Cytochrome P450 1A2 enzyme
Amitriptyline Alpha-2A adrenergic receptor target
Amitriptyline Potassium voltage-gated channel subfamily KQT member 2 target
Amitriptyline Sodium-dependent noradrenaline transporter target
Amitriptyline Sodium-dependent serotonin transporter target
Amitriptyline Cytochrome P450 3A5 enzyme
Amitriptyline Potassium voltage-gated channel subfamily A member 1 target
Amitriptyline Alpha-1D adrenergic receptor target
Amitriptyline Delta-type opioid receptor target
Amitriptyline Kappa-type opioid receptor target
Amitriptyline High affinity nerve growth factor receptor target
Amitriptyline BDNF/NT-3 growth factors receptor target
Amitriptyline Cytochrome P450 2C9 enzyme
Amitriptyline Cytochrome P450 2B6 enzyme
Amitriptyline Cytochrome P450 2C8 enzyme
Amitriptyline Histamine H2 receptor target
Amitriptyline Histamine H4 receptor target
Amitriptyline Sigma non-opioid intracellular receptor 1 target
Amitriptyline 5-hydroxytryptamine receptor 2C target
Amitriptyline Alpha-1B adrenergic receptor target
Amitriptyline 5-hydroxytryptamine receptor 7 target
Amitriptyline 5-hydroxytryptamine receptor 1D target
Amitriptyline Mu-type opioid receptor target
Amitriptyline 5-hydroxytryptamine receptor 1B target
Amitriptyline 5-hydroxytryptamine receptor 6 target
Amitriptyline Potassium voltage-gated channel subfamily KQT member 3 target
Amitriptyline UDP-glucuronosyltransferase 2B10 enzyme
Amitriptyline 5-hydroxytryptamine receptor 2C target
Amitriptyline Muscarinic acetylcholine receptor target
Amitriptyline HERG human cardiac K+ channel target
Amitriptyline ATP-dependent translocase ABCB1 transporter
Amitriptyline Glutathione S-transferases (Cytosolic) enzyme
Amitriptyline Cytochrome P450 3A4 enzyme
Aprocitentan Endothelin-1 receptor target
Aprocitentan Endothelin receptor type B target
Aprocitentan UDP-glucuronosyltransferase 1A1 enzyme
Aprocitentan UDP-glucuronosyltransferase 2B7 enzyme
Aprocitentan Albumin carrier
Aprocitentan Cytochrome P450 3A4 enzyme
Aprocitentan Cytochrome P450 2C8 enzyme
Aprocitentan Cytochrome P450 2C9 enzyme
Aprocitentan Cytochrome P450 2C18 enzyme
Aprocitentan Cytochrome P450 2C19 enzyme
Aprocitentan ATP-dependent translocase ABCB1 transporter
Aprocitentan Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Aprocitentan Bile salt export pump transporter
Aprocitentan Hepatic sodium/bile acid cotransporter transporter
Asciminib Cytochrome P450 3A4 enzyme
Asciminib UDP-glucuronosyltransferase 2B7 enzyme
Asciminib UDP-glucuronosyltransferase 2B17 enzyme
Asciminib Tyrosine-protein kinase ABL1 target
Asciminib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Asciminib UDP-glucuronosyltransferase 1A1 enzyme
Asciminib Cytochrome P450 2C19 enzyme
Asciminib ATP-dependent translocase ABCB1 transporter
Asciminib Solute carrier organic anion transporter family member 1B1 transporter
Asciminib Solute carrier organic anion transporter family member 1B3 transporter
Asciminib Solute carrier family 22 member 1 transporter
Asciminib Cytochrome P450 2C9 enzyme
Atazanavir Solute carrier organic anion transporter family member 1B3 transporter
Atazanavir Pol polyprotein target
Atazanavir Cytochrome P450 3A4 enzyme
Atazanavir Cytochrome P450 2C9 enzyme
Atazanavir ATP-dependent translocase ABCB1 transporter
Atazanavir Multidrug resistance-associated protein 1 transporter
Atazanavir Albumin carrier
Atazanavir UDP-glucuronosyltransferase 1A1 enzyme
Atazanavir Solute carrier organic anion transporter family member 1B1 transporter
Atazanavir Cytochrome P450 2C8 enzyme
Atazanavir Bile salt export pump transporter
Atazanavir alpha1-acid glycoprotein carrier
Atazanavir Gag-Pol polyprotein target
Atazanavir Cytochrome P450 3A7 enzyme
Atazanavir Cytochrome P450 3A5 enzyme
Atazanavir Solute carrier organic anion transporter family member 2B1 transporter
Atazanavir Cytochrome P450 1A2 enzyme
Belumosudil Rho-associated protein kinase 2 target
Belumosudil Albumin carrier
Belumosudil Alpha-1-acid glycoprotein 1 carrier
Belumosudil Rho-associated protein kinase 1 target
Belumosudil Cytochrome P450 3A4 enzyme
Belumosudil Cytochrome P450 2C8 enzyme
Belumosudil Cytochrome P450 2D6 enzyme
Belumosudil UDP-glucuronosyltransferase 1A9 enzyme
Belumosudil Cytochrome P450 1A2 enzyme
Belumosudil Cytochrome P450 2C19 enzyme
Belumosudil UDP-glucuronosyltransferase 1A1 enzyme
Belumosudil ATP-dependent translocase ABCB1 transporter
Belumosudil Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Belumosudil Solute carrier organic anion transporter family member 1B1 transporter
Dabrafenib Cytochrome P450 2C9 enzyme
Dabrafenib Cytochrome P450 2C19 enzyme
Dabrafenib Cytochrome P450 1A2 enzyme
Dabrafenib Albumin carrier
Dabrafenib Solute carrier organic anion transporter family member 1A2 transporter
Dabrafenib Solute carrier family 22 member 2 transporter
Dabrafenib UDP-glucuronosyltransferase 1A1 enzyme
Dabrafenib Cytochrome P450 2C8 enzyme
Dabrafenib ATP-dependent translocase ABCB1 transporter
Dabrafenib Cytochrome P450 3A4 enzyme
Dabrafenib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Dabrafenib Solute carrier organic anion transporter family member 1B1 transporter
Dabrafenib Solute carrier organic anion transporter family member 1B3 transporter
Dabrafenib Solute carrier family 22 member 6 transporter
Dabrafenib Organic anion transporter 3 transporter
Dabrafenib Serine/threonine-protein kinase B-raf target
Dabrafenib RAF proto-oncogene serine/threonine-protein kinase target
Dabrafenib Serine/threonine-protein kinase SIK1 target
Dabrafenib Serine/threonine-protein kinase Nek11 target
Dabrafenib Cytochrome P450 2B6 enzyme
Dabrafenib LIM domain kinase 1 target
Dacomitinib Receptor tyrosine-protein kinase erbB-2 target
Dacomitinib Receptor tyrosine-protein kinase erbB-4 target
Dacomitinib Epidermal growth factor receptor target
Dacomitinib Solute carrier family 22 member 1 transporter
Dacomitinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Dacomitinib ATP-dependent translocase ABCB1 transporter
Dacomitinib UDP-glucuronosyltransferase 1A1 enzyme
Dacomitinib Cytochrome P450 2C9 enzyme
Dacomitinib Cytochrome P450 3A4 enzyme
Dacomitinib Albumin carrier
Dacomitinib Cytochrome P450 2D6 enzyme
Dasabuvir Nonstructural protein 5b target
Dasabuvir Cytochrome P450 2C8 enzyme
Dasabuvir Cytochrome P450 3A4 enzyme
Dasabuvir Cytochrome P450 2D6 enzyme
Dasabuvir RNA-directed RNA polymerase target
Dasabuvir Genome polyprotein target
Dasabuvir ATP-dependent translocase ABCB1 transporter
Dasabuvir ATP-binding cassette sub-family B member 5 transporter
Dasabuvir Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Dasabuvir UDP-glucuronosyltransferase 1A1 enzyme
Defactinib Focal adhesion kinase 1 target
Defactinib Protein-tyrosine kinase 2-beta target
Defactinib Cytochrome P450 3A4 enzyme
Defactinib Cytochrome P450 2C9 enzyme
Defactinib Cytochrome P450 2B6 enzyme
Defactinib Cytochrome P450 1A2 enzyme
Defactinib UDP-glucuronosyltransferase 1A1 enzyme
Defactinib ATP-binding cassette sub-family B member 5 transporter
Defactinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Defactinib Solute carrier organic anion transporter family member 1B3 transporter
Defactinib Multidrug and toxin extrusion protein 2 transporter
Defactinib Solute carrier organic anion transporter family member 1B1 transporter
Deferasirox Iron target
Deferasirox Cytochrome P450 3A4 enzyme
Deferasirox UDP-glucuronosyltransferase 1A1 enzyme
Deferasirox UDP-glucuronosyltransferase 1A3 enzyme
Deferasirox UDP-glucuronosyltransferase 1A9 enzyme
Deferasirox Cytochrome P450 2C8 enzyme
Deferasirox Cytochrome P450 1A2 enzyme
Eltrombopag Thrombopoietin receptor target
Eltrombopag Cytochrome P450 2C8 enzyme
Eltrombopag Cytochrome P450 1A2 enzyme
Eltrombopag UDP-glucuronosyltransferase 1A1 enzyme
Eltrombopag UDP-glucuronosyltransferase 1A3 enzyme
Eltrombopag Solute carrier organic anion transporter family member 1B1 transporter
Eltrombopag Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Eltrombopag UDP-glucuronosyltransferase 1A9 enzyme
Enasidenib Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial target
Enasidenib ATP-dependent translocase ABCB1 transporter
Enasidenib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Enasidenib Solute carrier family 22 member 6 transporter
Enasidenib Solute carrier organic anion transporter family member 1B1 transporter
Enasidenib Solute carrier family 22 member 2 transporter
Enasidenib Solute carrier organic anion transporter family member 1B3 transporter
Enasidenib Organic anion transporter 3 transporter
Enasidenib Albumin carrier
Enasidenib Isocitrate dehydrogenase [NADP] cytoplasmic target
Enasidenib Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial target
Enasidenib UDP-glucuronosyltransferase 2B15 enzyme
Enasidenib UDP-glucuronosyltransferase 2B7 enzyme
Enasidenib UDP-glucuronosyltransferase 1A9 enzyme
Enasidenib UDP-glucuronosyltransferase 1A4 enzyme
Enasidenib UDP-glucuronosyltransferase 1A3 enzyme
Enasidenib UDP-glucuronosyltransferase 1A1 enzyme
Enasidenib Cytochrome P450 3A4 enzyme
Enasidenib Cytochrome P450 2D6 enzyme
Enasidenib Cytochrome P450 2C19 enzyme
Enasidenib Cytochrome P450 2C9 enzyme
Enasidenib Cytochrome P450 2C8 enzyme
Enasidenib Isocitrate dehydrogenase [NADP], mitochondrial target
Enasidenib Cytochrome P450 2B6 enzyme
Enasidenib Cytochrome P450 1A2 enzyme
Enasidenib Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial target
Encorafenib LIM domain kinase 2 target
Encorafenib Mitogen-activated protein kinase 10 target
Encorafenib Serine/threonine-protein kinase 36 target
Encorafenib Cytochrome P450 3A4 enzyme
Encorafenib Cytochrome P450 2C19 enzyme
Encorafenib Cytochrome P450 2D6 enzyme
Encorafenib Serine/threonine-protein kinase B-raf target
Encorafenib G1/S-specific cyclin-D1 target
Encorafenib UDP-glucuronosyltransferase 1A1 enzyme
Encorafenib Albumin carrier
Encorafenib Cytochrome P450 1A2 enzyme
Encorafenib Cytochrome P450 2B6 enzyme
Encorafenib Cytochrome P450 2C8 enzyme
Encorafenib Cytochrome P450 2C9 enzyme
Encorafenib Cytochrome P450 3A5 enzyme
Encorafenib Cytochrome P450 3A7 enzyme
Encorafenib ATP-dependent translocase ABCB1 transporter
Encorafenib Solute carrier family 22 member 2 transporter
Encorafenib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Encorafenib Solute carrier family 22 member 6 transporter
Encorafenib Organic anion transporter 3 transporter
Encorafenib Solute carrier organic anion transporter family member 1B1 transporter
Encorafenib Solute carrier organic anion transporter family member 1B3 transporter
Encorafenib RAF proto-oncogene serine/threonine-protein kinase target
Encorafenib Mitogen-activated protein kinase 8 target
Encorafenib Mitogen-activated protein kinase 9 target
Encorafenib Dual specificity mitogen-activated protein kinase kinase 4 target
Encorafenib LIM domain kinase 1 target
Erlotinib UDP-glucuronosyltransferase 1A1 enzyme
Erlotinib Cytochrome P450 2C8 enzyme
Erlotinib Cytochrome P450 2D6 enzyme
Erlotinib Cytochrome P450 1B1 enzyme
Erlotinib Cytochrome P450 1A2 enzyme
Erlotinib Cytochrome P450 1A1 enzyme
Erlotinib Cytochrome P450 3A5 enzyme
Erlotinib Nuclear receptor subfamily 1 group I member 2 target
Erlotinib ATP-dependent translocase ABCB1 transporter
Erlotinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Erlotinib Albumin carrier
Erlotinib Alpha-1-acid glycoprotein 1 carrier
Erlotinib Solute carrier organic anion transporter family member 2B1 transporter
Erlotinib Epidermal growth factor receptor enzyme
Erlotinib Cytochrome P450 3A4 enzyme
Erlotinib Epidermal growth factor receptor target
Ertugliflozin UDP-glucuronosyltransferase 1A4 enzyme
Ertugliflozin UDP-glucuronosyltransferase 1A1 enzyme
Ertugliflozin Albumin carrier
Ertugliflozin Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Ertugliflozin ATP-dependent translocase ABCB1 transporter
Ertugliflozin Sodium/glucose cotransporter 2 target
Ertugliflozin UDP-glucuronosyltransferase 2B7 enzyme
Ertugliflozin UDP-glucuronosyltransferase 1A9 enzyme
Flunitrazepam Cytochrome P450 2B6 enzyme
Flunitrazepam Cytochrome P450 2A6 enzyme
Flunitrazepam UDP-glucuronosyltransferase 2B7 enzyme
Flunitrazepam Cytochrome P450 2C19 enzyme
Flunitrazepam Translocator protein target
Flunitrazepam GABA(A) Receptor Benzodiazepine Binding Site target
Flunitrazepam Cytochrome P450 2C9 enzyme
Flunitrazepam Cytochrome P450 3A4 enzyme
Flunitrazepam Cytochrome P450 2E1 enzyme
Flunitrazepam UDP-glucuronosyltransferase 1A1 enzyme
Flunitrazepam UDP-glucuronosyltransferase 1A3 enzyme
Flunitrazepam GABA(A) Receptor target
Flurbiprofen Prostaglandin G/H synthase 2 target
Flurbiprofen Prostaglandin G/H synthase 1 target
Flurbiprofen Cytochrome P450 2C9 enzyme
Flurbiprofen Albumin carrier
Flurbiprofen ATP-binding cassette sub-family C member 4 transporter
Flurbiprofen Solute carrier family 22 member 6 transporter
Flurbiprofen UDP-glucuronosyltransferase 2B7 enzyme
Flurbiprofen UDP-glucuronosyltransferase 1A1 enzyme
Flurbiprofen UDP-glucuronosyltransferase 1A3 enzyme
Flurbiprofen UDP-glucuronosyltransferase 1A9 enzyme
Flurbiprofen UDP-glucuronosyltransferase 2B4 enzyme
Flurbiprofen Human Cyclooxygenases target
Fostamatinib SNF-related serine/threonine-protein kinase target
Fostamatinib STE20-like serine/threonine-protein kinase target
Fostamatinib Serine/threonine-protein kinase SIK2 target
Fostamatinib Serine/threonine-protein kinase SIK1 target
Fostamatinib Serine/threonine-protein kinase Sgk3 target
Fostamatinib Uncharacterized serine/threonine-protein kinase SBK3 target
Fostamatinib Serine/threonine-protein kinase SBK1 target
Fostamatinib Ribosomal protein S6 kinase alpha-3 target
Fostamatinib Proto-oncogene tyrosine-protein kinase Src target
Fostamatinib Tyrosine-protein kinase Srms target
Fostamatinib Serine/threonine-protein kinase 10 target
Fostamatinib Serine/threonine-protein kinase 16 target
Fostamatinib Serine/threonine-protein kinase 17A target
Fostamatinib Serine/threonine-protein kinase 17B target
Fostamatinib Serine/threonine-protein kinase 32A target
Fostamatinib Cytochrome P450 3A4 enzyme
Fostamatinib UDP-glucuronosyltransferase 1A9 enzyme
Fostamatinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Fostamatinib ATP-binding cassette sub-family B member 5 transporter
Fostamatinib Ribosomal protein S6 kinase alpha-1 target
Fostamatinib Serine/threonine-protein kinase 38 target
Fostamatinib Serine/threonine-protein kinase TAO3 target
Fostamatinib Casein kinase II subunit alpha' target
Fostamatinib Casein kinase II subunit alpha target
Fostamatinib Casein kinase I isoform alpha target
Fostamatinib Tyrosine-protein kinase CSK target
Fostamatinib Macrophage colony-stimulating factor 1 receptor target
Fostamatinib Dual specificity protein kinase CLK4 target
Fostamatinib Dual specificity protein kinase CLK3 target
Fostamatinib Dual specificity protein kinase CLK2 target
Fostamatinib Dual specificity protein kinase CLK1 target
Fostamatinib Citron Rho-interacting kinase target
Fostamatinib Serine/threonine-protein kinase Chk2 target
Fostamatinib Serine/threonine-protein kinase Chk1 target
Fostamatinib Cyclin-dependent kinase-like 2 target
Fostamatinib Cyclin-dependent kinase-like 1 target
Fostamatinib Cyclin-dependent kinase 4 target
Fostamatinib Serine/threonine-protein kinase MRCK gamma target
Fostamatinib Cyclin-dependent kinase 1 target
Fostamatinib Kappa-casein target
Fostamatinib Peripheral plasma membrane protein CASK target
Fostamatinib Calcium/calmodulin-dependent protein kinase kinase 2 target
Fostamatinib Calcium/calmodulin-dependent protein kinase kinase 1 target
Fostamatinib Calcium/calmodulin-dependent protein kinase type II subunit gamma target
Fostamatinib Calcium/calmodulin-dependent protein kinase type II subunit delta target
Fostamatinib Calcium/calmodulin-dependent protein kinase type II subunit beta target
Fostamatinib Calcium/calmodulin-dependent protein kinase type II subunit alpha target
Fostamatinib Calcium/calmodulin-dependent protein kinase type 1G target
Fostamatinib Calcium/calmodulin-dependent protein kinase type 1D target
Fostamatinib Calcium/calmodulin-dependent protein kinase type 1 target
Fostamatinib Tyrosine-protein kinase BTK target
Fostamatinib Serine/threonine-protein kinase B-raf target
Fostamatinib Cytoplasmic tyrosine-protein kinase BMX target
Fostamatinib Bone morphogenetic protein receptor type-2 target
Fostamatinib Bone morphogenetic protein receptor type-1B target
Fostamatinib BMP-2-inducible protein kinase target
Fostamatinib Tyrosine-protein kinase Blk target
Fostamatinib Tyrosine-protein kinase receptor UFO target
Fostamatinib Aurora kinase C target
Fostamatinib Aurora kinase B target
Fostamatinib Adenosine receptor A3 target
Fostamatinib Synaptic vesicular amine transporter target
Fostamatinib Fatty-acid amide hydrolase 1 target
Fostamatinib Equilibrative nucleoside transporter 1 target
Fostamatinib UDP-glucuronosyltransferase 1A1 target
Fostamatinib cGMP-specific 3',5'-cyclic phosphodiesterase target
Fostamatinib Polyunsaturated fatty acid 5-lipoxygenase target
Fostamatinib Cathepsin S target
Fostamatinib Procathepsin L target
Fostamatinib Tyrosine-protein kinase ABL1 target
Fostamatinib Calcium-dependent protein kinase 1 target
Fostamatinib Serine/threonine-protein kinase PknB target
Fostamatinib Ribosomal protein S6 kinase alpha-6 target
Fostamatinib Non-receptor tyrosine-protein kinase TYK2 target
Fostamatinib Atypical kinase COQ8A, mitochondrial target
Fostamatinib Tyrosine-protein kinase JAK1 target
Fostamatinib Hepatocyte growth factor receptor target
Fostamatinib Serine/threonine-protein kinase NIM1 target
Fostamatinib Serine/threonine-protein kinase 26 target
Fostamatinib cAMP-dependent protein kinase catalytic subunit alpha target
Fostamatinib Serine/threonine-protein kinase 24 target
Fostamatinib Serine/threonine-protein kinase 3 target
Fostamatinib Tyrosine-protein kinase Tec target
Fostamatinib Tyrosine-protein kinase SYK target
Fostamatinib Serine/threonine-protein kinase 33 target
Fostamatinib Serine/threonine-protein kinase 35 target
Fostamatinib Serine/threonine-protein kinase 36 target
Fostamatinib Aurora kinase A target
Fostamatinib Serine/threonine-protein kinase 38-like target
Fostamatinib STE20/SPS1-related proline-alanine-rich protein kinase target
Fostamatinib Serine/threonine-protein kinase TAO1 target
Fostamatinib Serine/threonine-protein kinase TAO2 target
Fostamatinib Death-associated protein kinase 1 target
Fostamatinib Serine/threonine-protein kinase TBK1 target
Fostamatinib Angiopoietin-1 receptor target
Fostamatinib Dual specificity testis-specific protein kinase 1 target
Fostamatinib TGF-beta receptor type-1 target
Fostamatinib TGF-beta receptor type-2 target
Fostamatinib Tyrosine-protein kinase receptor Tie-1 target
Fostamatinib Serine/threonine-protein kinase tousled-like 1 target
Fostamatinib Serine/threonine-protein kinase tousled-like 2 target
Fostamatinib TRAF2 and NCK-interacting protein kinase target
Fostamatinib Non-receptor tyrosine-protein kinase TNK1 target
Fostamatinib Activated CDC42 kinase 1 target
Fostamatinib Serine/threonine-protein kinase TNNI3K target
Fostamatinib Testis-specific serine/threonine-protein kinase 1 target
Fostamatinib Dual specificity protein kinase TTK target
Fostamatinib Tyrosine-protein kinase TXK target
Fostamatinib Tyrosine-protein kinase receptor TYRO3 target
Fostamatinib Serine/threonine-protein kinase ULK1 target
Fostamatinib Serine/threonine-protein kinase ULK2 target
Fostamatinib Serine/threonine-protein kinase ULK3 target
Fostamatinib Wee1-like protein kinase target
Fostamatinib Tyrosine-protein kinase Yes target
Fostamatinib Mitogen-activated protein kinase kinase kinase 19 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 20 target
Fostamatinib Tyrosine-protein kinase ZAP-70 target
Fostamatinib AP2-associated protein kinase 1 target
Fostamatinib Tyrosine-protein kinase ABL2 target
Fostamatinib Activin receptor type-1 target
Fostamatinib Activin receptor type-1B target
Fostamatinib Atypical kinase COQ8B, mitochondrial target
Fostamatinib ALK tyrosine kinase receptor target
Fostamatinib Ankyrin repeat and protein kinase domain-containing protein 1 target
Fostamatinib Death-associated protein kinase 2 target
Fostamatinib Death-associated protein kinase 3 target
Fostamatinib Serine/threonine-protein kinase DCLK1 target
Fostamatinib Serine/threonine-protein kinase DCLK2 target
Fostamatinib Serine/threonine-protein kinase DCLK3 target
Fostamatinib Epithelial discoidin domain-containing receptor 1 target
Fostamatinib Discoidin domain-containing receptor 2 target
Fostamatinib Dual specificity tyrosine-phosphorylation-regulated kinase 1A target
Fostamatinib Dual specificity tyrosine-phosphorylation-regulated kinase 1B target
Fostamatinib Epidermal growth factor receptor target
Fostamatinib Eukaryotic translation initiation factor 2-alpha kinase 1 target
Fostamatinib Interferon-induced, double-stranded RNA-activated protein kinase target
Fostamatinib eIF-2-alpha kinase GCN2 target
Fostamatinib Ephrin type-A receptor 1 target
Fostamatinib Ephrin type-A receptor 2 target
Fostamatinib Ephrin type-A receptor 3 target
Fostamatinib Ephrin type-A receptor 4 target
Fostamatinib Ephrin type-A receptor 5 target
Fostamatinib Ephrin type-A receptor 6 target
Fostamatinib Ephrin type-A receptor 7 target
Fostamatinib Ephrin type-A receptor 8 target
Fostamatinib Ephrin type-B receptor 1 target
Fostamatinib Ephrin type-B receptor 2 target
Fostamatinib Ephrin type-B receptor 4 target
Fostamatinib Ephrin type-B receptor 6 target
Fostamatinib Receptor tyrosine-protein kinase erbB-2 target
Fostamatinib Receptor tyrosine-protein kinase erbB-4 target
Fostamatinib Serine/threonine-protein kinase/endoribonuclease IRE1 target
Fostamatinib Tyrosine-protein kinase Fer target
Fostamatinib Tyrosine-protein kinase Fes/Fps target
Fostamatinib Fibroblast growth factor receptor 1 target
Fostamatinib Fibroblast growth factor receptor 2 target
Fostamatinib Fibroblast growth factor receptor 3 target
Fostamatinib Tyrosine-protein kinase Fgr target
Fostamatinib Vascular endothelial growth factor receptor 1 target
Fostamatinib Receptor-type tyrosine-protein kinase FLT3 target
Fostamatinib Vascular endothelial growth factor receptor 3 target
Fostamatinib Serine/threonine-protein kinase mTOR target
Fostamatinib Tyrosine-protein kinase FRK target
Fostamatinib Tyrosine-protein kinase Fyn target
Fostamatinib Cyclin-G-associated kinase target
Fostamatinib Glycogen synthase kinase-3 alpha target
Fostamatinib Glycogen synthase kinase-3 beta target
Fostamatinib Tyrosine-protein kinase HCK target
Fostamatinib Homeodomain-interacting protein kinase 2 target
Fostamatinib Homeodomain-interacting protein kinase 3 target
Fostamatinib Serine/threonine-protein kinase ICK target
Fostamatinib Inhibitor of nuclear factor kappa-B kinase subunit beta target
Fostamatinib Inhibitor of nuclear factor kappa-B kinase subunit epsilon target
Fostamatinib Insulin receptor target
Fostamatinib Insulin receptor-related protein target
Fostamatinib Interleukin-1 receptor-associated kinase 1 target
Fostamatinib Interleukin-1 receptor-associated kinase 3 target
Fostamatinib Interleukin-1 receptor-associated kinase 4 target
Fostamatinib Tyrosine-protein kinase ITK/TSK target
Fostamatinib Tyrosine-protein kinase JAK2 target
Fostamatinib Tyrosine-protein kinase JAK3 target
Fostamatinib Vascular endothelial growth factor receptor 2 target
Fostamatinib Serine/threonine-protein kinase SIK3 target
Fostamatinib Mast/stem cell growth factor receptor Kit target
Fostamatinib Serine/threonine-protein kinase LATS1 target
Fostamatinib Tyrosine-protein kinase Lck target
Fostamatinib LIM domain kinase 1 target
Fostamatinib LIM domain kinase 2 target
Fostamatinib Leucine-rich repeat serine/threonine-protein kinase 2 target
Fostamatinib Leukocyte tyrosine kinase receptor target
Fostamatinib Tyrosine-protein kinase Lyn target
Fostamatinib Dual specificity mitogen-activated protein kinase kinase 2 target
Fostamatinib Dual specificity mitogen-activated protein kinase kinase 3 target
Fostamatinib Dual specificity mitogen-activated protein kinase kinase 5 target
Fostamatinib Dual specificity mitogen-activated protein kinase kinase 6 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 1 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 10 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 11 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 12 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 13 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 15 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 2 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 3 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 4 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 6 target
Fostamatinib Mitogen-activated protein kinase kinase kinase 9 target
Fostamatinib Mitogen-activated protein kinase kinase kinase kinase 1 target
Fostamatinib Mitogen-activated protein kinase kinase kinase kinase 2 target
Fostamatinib Mitogen-activated protein kinase kinase kinase kinase 3 target
Fostamatinib Mitogen-activated protein kinase kinase kinase kinase 4 target
Fostamatinib Mitogen-activated protein kinase kinase kinase kinase 5 target
Fostamatinib Mitogen-activated protein kinase 10 target
Fostamatinib Mitogen-activated protein kinase 13 target
Fostamatinib Mitogen-activated protein kinase 14 target
Fostamatinib Mitogen-activated protein kinase 15 target
Fostamatinib Mitogen-activated protein kinase 4 target
Fostamatinib Mitogen-activated protein kinase 7 target
Fostamatinib Mitogen-activated protein kinase 9 target
Fostamatinib MAP kinase-activated protein kinase 5 target
Fostamatinib Serine/threonine-protein kinase MARK1 target
Fostamatinib Serine/threonine-protein kinase MARK2 target
Fostamatinib MAP/microtubule affinity-regulating kinase 3 target
Fostamatinib MAP/microtubule affinity-regulating kinase 4 target
Fostamatinib CLIP-associating protein 1 target
Fostamatinib Microtubule-associated serine/threonine-protein kinase 1 target
Fostamatinib Megakaryocyte-associated tyrosine-protein kinase target
Fostamatinib Maternal embryonic leucine zipper kinase target
Fostamatinib Tyrosine-protein kinase Mer target
Fostamatinib Misshapen-like kinase 1 target
Fostamatinib MAP kinase-interacting serine/threonine-protein kinase 1 target
Fostamatinib MAP kinase-interacting serine/threonine-protein kinase 2 target
Fostamatinib Macrophage-stimulating protein receptor target
Fostamatinib Muscle, skeletal receptor tyrosine-protein kinase target
Fostamatinib Myosin light chain kinase, smooth muscle target
Fostamatinib Myosin light chain kinase 2, skeletal/cardiac muscle target
Fostamatinib Myosin light chain kinase 3 target
Fostamatinib Myosin light chain kinase family member 4 target
Fostamatinib Myosin-IIIa target
Fostamatinib Serine/threonine-protein kinase Nek1 target
Fostamatinib Serine/threonine-protein kinase Nek11 target
Fostamatinib Serine/threonine-protein kinase Nek2 target
Fostamatinib Serine/threonine-protein kinase Nek3 target
Fostamatinib Serine/threonine-protein kinase Nek4 target
Fostamatinib Serine/threonine-protein kinase Nek5 target
Fostamatinib Serine/threonine-protein kinase Nek9 target
Fostamatinib High affinity nerve growth factor receptor target
Fostamatinib BDNF/NT-3 growth factors receptor target
Fostamatinib NT-3 growth factor receptor target
Fostamatinib NUAK family SNF1-like kinase 1 target
Fostamatinib NUAK family SNF1-like kinase 2 target
Fostamatinib Serine/threonine-protein kinase OSR1 target
Fostamatinib Serine/threonine-protein kinase PAK 1 target
Fostamatinib Serine/threonine-protein kinase PAK 2 target
Fostamatinib Serine/threonine-protein kinase PAK 3 target
Fostamatinib Serine/threonine-protein kinase PAK 4 target
Fostamatinib Serine/threonine-protein kinase PAK 6 target
Fostamatinib Serine/threonine-protein kinase PAK 5 target
Fostamatinib Cyclin-dependent kinase 16 target
Fostamatinib Cyclin-dependent kinase 17 target
Fostamatinib Platelet-derived growth factor receptor alpha target
Fostamatinib Platelet-derived growth factor receptor beta target
Fostamatinib 3-phosphoinositide-dependent protein kinase 1 target
Fostamatinib Cyclin-dependent kinase 15 target
Fostamatinib Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform target
Fostamatinib Phosphatidylinositol 4-kinase beta target
Fostamatinib Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta target
Fostamatinib Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma target
Fostamatinib Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform target
Fostamatinib Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform target
Fostamatinib Serine/threonine-protein kinase pim-1 target
Fostamatinib Serine/threonine-protein kinase pim-3 target
Fostamatinib Phosphatidylinositol 5-phosphate 4-kinase type-2 beta target
Fostamatinib Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma target
Fostamatinib Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase target
Fostamatinib Serine/threonine-protein kinase N1 target
Fostamatinib Serine/threonine-protein kinase N2 target
Fostamatinib Serine/threonine-protein kinase PLK1 target
Fostamatinib Serine/threonine-protein kinase PLK2 target
Fostamatinib Serine/threonine-protein kinase PLK3 target
Fostamatinib Serine/threonine-protein kinase PLK4 target
Fostamatinib 5'-AMP-activated protein kinase catalytic subunit alpha-1 target
Fostamatinib 5'-AMP-activated protein kinase target
Fostamatinib cAMP-dependent protein kinase catalytic subunit beta target
Fostamatinib Protein kinase C delta type target
Fostamatinib Protein kinase C epsilon type target
Fostamatinib Protein kinase C gamma type target
Fostamatinib Protein kinase C iota type target
Fostamatinib Protein kinase C theta type target
Fostamatinib Serine/threonine-protein kinase D1 target
Fostamatinib cGMP-dependent protein kinase 2 target
Fostamatinib Serine/threonine-protein kinase PRP4 homolog target
Fostamatinib Focal adhesion kinase 1 target
Fostamatinib Protein-tyrosine kinase 2-beta target
Fostamatinib Protein-tyrosine kinase 6 target
Fostamatinib RAF proto-oncogene serine/threonine-protein kinase target
Fostamatinib Proto-oncogene tyrosine-protein kinase receptor Ret target
Fostamatinib Serine/threonine-protein kinase RIO1 target
Fostamatinib Serine/threonine-protein kinase RIO2 target
Fostamatinib Serine/threonine-protein kinase RIO3 target
Fostamatinib Receptor-interacting serine/threonine-protein kinase 1 target
Fostamatinib Receptor-interacting serine/threonine-protein kinase 2 target
Fostamatinib Receptor-interacting serine/threonine-protein kinase 4 target
Fostamatinib Rho-associated protein kinase 2 target
Fostamatinib Proto-oncogene tyrosine-protein kinase ROS target
Gemfibrozil Lipoprotein lipase target
Gemfibrozil Solute carrier organic anion transporter family member 1B3 target
Gemfibrozil Solute carrier organic anion transporter family member 2B1 target
Gemfibrozil Organic anion transporter 3 target
Gemfibrozil Albumin carrier
Gemfibrozil UDP-glucuronosyltransferase 2B17 enzyme
Gemfibrozil UDP-glucuronosyltransferase 2B4 enzyme
Gemfibrozil UDP-glucuronosyltransferase 1A9 enzyme
Gemfibrozil UDP-glucuronosyltransferase 2B7 enzyme
Gemfibrozil Solute carrier organic anion transporter family member 1B1 target
Gemfibrozil UDP-glucuronosyltransferase 1A3 enzyme
Gemfibrozil Cytochrome P450 3A4 enzyme
Gemfibrozil UDP-glucuronosyltransferase 1A1 enzyme
Gemfibrozil Cytochrome P450 2C19 enzyme
Gemfibrozil Cytochrome P450 1A2 enzyme
Gemfibrozil Cytochrome P450 2C8 enzyme
Gemfibrozil Cytochrome P450 2C9 enzyme
Gemfibrozil Peroxisome proliferator-activated receptor alpha target
Glecaprevir UDP-glucuronosyltransferase 1A1 enzyme
Glecaprevir Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Glecaprevir Solute carrier organic anion transporter family member 1B1 transporter
Glecaprevir Solute carrier organic anion transporter family member 1B3 transporter
Glecaprevir NS3 protease target
Glecaprevir Cytochrome P450 3A4 enzyme
Glecaprevir Genome polyprotein target
Glecaprevir ATP-dependent translocase ABCB1 transporter
Glecaprevir Cytochrome P450 3A Subfamily enzyme
Indinavir Solute carrier organic anion transporter family member 2B1 transporter
Indinavir Bile salt export pump transporter
Indinavir Gag-Pol polyprotein target
Indinavir Solute carrier organic anion transporter family member 1A2 transporter
Indinavir Solute carrier organic anion transporter family member 1B1 transporter
Indinavir ATP-binding cassette sub-family C member 2 transporter
Indinavir Cytochrome P450 2D6 enzyme
Indinavir UDP-glucuronosyltransferase 1A1 enzyme
Indinavir Pol polyprotein target
Indinavir Cytochrome P450 3A4 enzyme
Indinavir Cytochrome P450 3A5 enzyme
Indinavir Cytochrome P450 3A7 enzyme
Indinavir ATP-dependent translocase ABCB1 transporter
Indinavir Solute carrier family 22 member 1 transporter
Indinavir Multidrug resistance-associated protein 1 transporter
Indomethacin UDP-glucuronosyltransferase 1A9 enzyme
Indomethacin Cytochrome P450 2C19 enzyme
Indomethacin Prostaglandin G/H synthase 2 target
Indomethacin Prostaglandin G/H synthase 1 target
Indomethacin Bile salt export pump transporter
Indomethacin Phospholipase A2, membrane associated target
Indomethacin Human Cyclooxygenases target
Indomethacin Solute carrier organic anion transporter family member 1B1 transporter
Indomethacin Aldo-keto reductase family 1 member C3 target
Indomethacin Peroxisome proliferator-activated receptor alpha target
Indomethacin UDP-glucuronosyltransferase 2B7 enzyme
Indomethacin Liver carboxylesterase 1 enzyme
Indomethacin UDP-glucuronosyltransferase 1A1 enzyme
Indomethacin Cytochrome P450 2C9 enzyme
Indomethacin Solute carrier family 22 member 7 transporter
Indomethacin Hepatic sodium/bile acid cotransporter transporter
Indomethacin Solute carrier family 22 member 11 transporter
Indomethacin ATP-binding cassette sub-family C member 11 transporter
Indomethacin ATP-binding cassette sub-family C member 2 transporter
Indomethacin Organic anion transporter 3 transporter
Indomethacin Solute carrier family 22 member 6 transporter
Indomethacin Solute carrier organic anion transporter family member 1A2 transporter
Indomethacin Multidrug resistance-associated protein 1 transporter
Indomethacin ATP-dependent translocase ABCB1 transporter
Indomethacin ATP-binding cassette sub-family C member 6 transporter
Indomethacin ATP-binding cassette sub-family C member 4 transporter
Indomethacin ATP-binding cassette sub-family C member 3 transporter
Indomethacin Albumin carrier
Indomethacin Peroxisome proliferator-activated receptor gamma target
Indomethacin Prostaglandin D2 receptor 2 target
Indomethacin Lactoylglutathione lyase target
Indomethacin Prostaglandin reductase 2 target
Indomethacin Interferon-induced, double-stranded RNA-activated protein kinase target
Ketoconazole Cytochrome P450 4F12 enzyme
Ketoconazole Cytochrome P450 3A4 enzyme
Ketoconazole Cytochrome P450 2C9 enzyme
Ketoconazole Cytochrome P450 2C19 enzyme
Ketoconazole Cytochrome P450 3A5 enzyme
Ketoconazole Cytochrome P450 1A2 enzyme
Ketoconazole Cytochrome P450 2C8 enzyme
Ketoconazole Cytochrome P450 1A1 enzyme
Ketoconazole Cytochrome P450 2D6 enzyme
Ketoconazole Bile salt export pump transporter
Ketoconazole ATP-dependent translocase ABCB1 transporter
Ketoconazole Cytochrome P450 11B1, mitochondrial enzyme
Ketoconazole Cytochrome P450 1B1 enzyme
Ketoconazole Cytochrome P450 2A6 enzyme
Ketoconazole Cytochrome P450 2B6 enzyme
Ketoconazole Lanosterol 14-alpha demethylase target
Ketoconazole Androgen receptor target
Ketoconazole Steroid 17-alpha-hydroxylase/17,20 lyase target
Ketoconazole Albumin carrier
Ketoconazole Sex hormone-binding globulin carrier
Ketoconazole Cytochrome P450 4F2 enzyme
Ketoconazole Aromatase enzyme
Ketoconazole UDP-glucuronosyltransferase 1A7 enzyme
Ketoconazole Lanosterol 14-alpha demethylase target
Ketoconazole Solute carrier organic anion transporter family member 1B1 transporter
Ketoconazole UDP-glucuronosyltransferase 2B7 enzyme
Ketoconazole UDP-glucuronosyltransferase 1A1 enzyme
Ketoconazole Steroid 21-hydroxylase target
Ketoconazole Voltage-gated inwardly rectifying potassium channel KCNH2 target
Ketoconazole Nuclear receptor subfamily 1 group I member 2 target
Ketoconazole Nuclear receptor subfamily 1 group I member 3 target
Lazertinib Solute carrier family 22 member 1 transporter
Lazertinib Cytochrome P450 3A4 enzyme
Lazertinib Epidermal growth factor receptor target
Lazertinib Glutathione S-transferase Mu 1 enzyme
Lazertinib UDP-glucuronosyltransferase 1A1 enzyme
Lazertinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Momelotinib Cytochrome P450 3A4 enzyme
Momelotinib Cytochrome P450 2C8 enzyme
Momelotinib Cytochrome P450 2C9 enzyme
Momelotinib Cytochrome P450 2C19 enzyme
Momelotinib Cytochrome P450 1A2 enzyme
Momelotinib Cytochrome P450 2B6 enzyme
Momelotinib UDP-glucuronosyltransferase 1A1 enzyme
Momelotinib UDP-glucuronosyltransferase 1A9 enzyme
Momelotinib ATP-dependent translocase ABCB1 transporter
Momelotinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Momelotinib Solute carrier organic anion transporter family member 1B1 transporter
Momelotinib Solute carrier organic anion transporter family member 1B3 transporter
Momelotinib Tyrosine-protein kinase JAK1 target
Momelotinib Tyrosine-protein kinase JAK2 target
Momelotinib Tyrosine-protein kinase JAK3 target
Momelotinib Non-receptor tyrosine-protein kinase TYK2 target
Momelotinib Activin receptor type-1 target
Momelotinib Receptor-type tyrosine-protein kinase FLT3 target
Nilotinib Tyrosine-protein kinase ABL1 target
Nilotinib Mast/stem cell growth factor receptor Kit target
Nilotinib Cytochrome P450 2D6 enzyme
Nilotinib Cytochrome P450 2C8 enzyme
Nilotinib Cytochrome P450 2C9 enzyme
Nilotinib Granulocyte colony-stimulating factor receptor target
Nilotinib Platelet-derived growth factor receptor target
Nilotinib Solute carrier organic anion transporter family member 1B1 transporter
Nilotinib Cytochrome P450 2B6 enzyme
Nilotinib UDP-glucuronosyltransferase 1A1 transporter
Nilotinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Nilotinib ATP-dependent translocase ABCB1 transporter
Nilotinib Cytochrome P450 3A4 enzyme
Nilotinib Discoidin domain receptor target
Olaparib Poly [ADP-ribose] polymerases target
Olaparib Alpha-1-acid glycoprotein 1 carrier
Olaparib Albumin carrier
Olaparib UDP-glucuronosyltransferase 1A1 enzyme
Olaparib Aldo-keto reductase family 1 member C3 target
Olaparib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Olaparib ATP-dependent translocase ABCB1 transporter
Olaparib Cytochrome P450 3A5 enzyme
Olaparib Protein mono-ADP-ribosyltransferase PARP3 target
Olaparib Poly [ADP-ribose] polymerase 2 target
Olaparib Cytochrome P450 2B6 enzyme
Olaparib Cytochrome P450 3A4 enzyme
Olaparib Poly [ADP-ribose] polymerase 1 target
Ombitasvir Nonstructural protein 5A target
Ombitasvir Cytochrome P450 2C8 enzyme
Ombitasvir ATP-dependent translocase ABCB1 transporter
Ombitasvir Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Ombitasvir UDP-glucuronosyltransferase 1A1 enzyme
Ombitasvir Genome polyprotein target
Osilodrostat Solute carrier organic anion transporter family member 1B1 transporter
Osilodrostat Cytochrome P450 2E1 enzyme
Osilodrostat Solute carrier family 22 member 1 transporter
Osilodrostat Solute carrier family 22 member 2 transporter
Osilodrostat Solute carrier family 22 member 6 transporter
Osilodrostat Organic anion transporter 3 transporter
Osilodrostat Multidrug and toxin extrusion protein 1 transporter
Osilodrostat UDP-glucuronosyltransferase 1A1 enzyme
Osilodrostat Cytochrome P450 2C19 enzyme
Osilodrostat Cytochrome P450 11B1, mitochondrial target
Osilodrostat Cytochrome P450 11B2, mitochondrial target
Osilodrostat Cytochrome P450 3A4 enzyme
Osilodrostat Cytochrome P450 2B6 enzyme
Osilodrostat Cytochrome P450 2D6 enzyme
Osilodrostat UDP-glucuronosyltransferase 1A4 enzyme
Osilodrostat UDP-glucuronosyltransferase 2B7 enzyme
Osilodrostat UDP-glucuronosyltransferase 2B10 enzyme
Osilodrostat Cytochrome P450 3A5 enzyme
Osilodrostat Cytochrome P450 1A2 enzyme
Paltusotine Somatostatin receptor type 2 target
Paltusotine UDP-glucuronosyltransferase 1A1 enzyme
Paltusotine UDP-glucuronosyltransferase 1A9 enzyme
Paltusotine Cytochrome P450 3A4 enzyme
Paltusotine Cytochrome P450 3A5 enzyme
Paltusotine Cytochrome P450 2D6 enzyme
Paltusotine UDP-glucuronosyltransferase 1A3 enzyme
Paltusotine Cytochrome P450 2C19 enzyme
Paltusotine ATP-dependent translocase ABCB1 transporter
Paltusotine Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Paltusotine Multidrug and toxin extrusion protein 1 transporter
Paltusotine Multidrug and toxin extrusion protein 2 transporter
Paltusotine Bile salt export pump transporter
Paritaprevir Gag-Pol polyprotein target
Paritaprevir UDP-glucuronosyltransferase 1A1 enzyme
Paritaprevir Solute carrier organic anion transporter family member 1B3 transporter
Paritaprevir Solute carrier organic anion transporter family member 1B1 transporter
Paritaprevir ATP-dependent translocase ABCB1 transporter
Paritaprevir Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Paritaprevir Cytochrome P450 3A5 enzyme
Paritaprevir Cytochrome P450 3A4 enzyme
Paritaprevir Genome polyprotein target
Pazopanib Vascular endothelial growth factor receptor target
Pazopanib Fibroblast growth factor receptor 1 target
Pazopanib Tyrosine-protein kinase Lck target
Pazopanib Macrophage colony-stimulating factor 1 receptor target
Pazopanib SH2B adapter protein 3 target
Pazopanib Fibroblast growth factor 1 target
Pazopanib Tyrosine-protein kinase ITK/TSK target
Pazopanib Fibroblast growth factor receptor 3 target
Pazopanib UDP-glucuronosyltransferase 1A1 transporter
Pazopanib Solute carrier organic anion transporter family member 1B1 transporter
Pazopanib Vascular endothelial growth factor receptor 1 target
Pazopanib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Pazopanib ATP-dependent translocase ABCB1 transporter
Pazopanib Cytochrome P450 1A2 enzyme
Pazopanib Cytochrome P450 2C8 enzyme
Pazopanib Cytochrome P450 2D6 enzyme
Pazopanib Cytochrome P450 3A4 enzyme
Pazopanib Mast/stem cell growth factor receptor Kit target
Pazopanib Platelet-derived growth factor receptor beta target
Pazopanib Platelet-derived growth factor receptor alpha target
Pazopanib Vascular endothelial growth factor receptor 3 target
Pazopanib Vascular endothelial growth factor receptor 2 target
Pexidartinib Multidrug and toxin extrusion protein 2 transporter
Pexidartinib Platelet-derived growth factor receptor beta target
Pexidartinib Receptor-type tyrosine-protein kinase FLT3 target
Pexidartinib Mast/stem cell growth factor receptor Kit target
Pexidartinib Alpha-1-acid glycoprotein 1 carrier
Pexidartinib Albumin carrier
Pexidartinib Solute carrier organic anion transporter family member 2B1 transporter
Pexidartinib Solute carrier organic anion transporter family member 1B3 transporter
Pexidartinib Solute carrier organic anion transporter family member 1B1 transporter
Pexidartinib Cytochrome P450 3A4 enzyme
Pexidartinib Multidrug and toxin extrusion protein 1 transporter
Pexidartinib UDP-glucuronosyltransferase 1A1 enzyme
Pexidartinib Cytochrome P450 2C9 enzyme
Pexidartinib Cytochrome P450 2B6 enzyme
Pexidartinib Macrophage colony-stimulating factor 1 receptor target
Pexidartinib UDP-glucuronosyltransferase 1A4 enzyme
Pibrentasvir Nonstructural protein 5A target
Pibrentasvir Cytochrome P450 3A Subfamily enzyme
Pibrentasvir UDP-glucuronosyltransferase 1A1 enzyme
Pibrentasvir ATP-dependent translocase ABCB1 transporter
Pibrentasvir Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Pibrentasvir Solute carrier organic anion transporter family member 1B1 transporter
Pibrentasvir Solute carrier organic anion transporter family member 1B3 transporter
Probenecid Solute carrier organic anion transporter family member 1A2 transporter
Probenecid Multidrug resistance-associated protein 1 transporter
Probenecid ATP-binding cassette sub-family C member 6 transporter
Probenecid Organic cation/carnitine transporter 2 transporter
Probenecid Monocarboxylate transporter 2 transporter
Probenecid ATP-binding cassette sub-family C member 5 transporter
Probenecid ATP-binding cassette sub-family C member 4 transporter
Probenecid ATP-binding cassette sub-family C member 3 transporter
Probenecid Solute carrier family 22 member 1 transporter
Probenecid Solute carrier family 22 member 2 transporter
Probenecid Albumin carrier
Probenecid Solute carrier family 22 member 11 target
Probenecid Organic anion transporter 3 target
Probenecid Monocarboxylate transporter 1 transporter
Probenecid Hepatic sodium/bile acid cotransporter transporter
Probenecid Solute carrier family 22 member 6 transporter
Probenecid Solute carrier family 22 member 10 transporter
Probenecid Organic anion transporter 3 transporter
Probenecid ATP-binding cassette sub-family C member 2 transporter
Probenecid ATP-binding cassette sub-family C member 11 transporter
Probenecid Solute carrier family 22 member 11 transporter
Probenecid Solute carrier organic anion transporter family member 1C1 transporter
Probenecid Solute carrier family 22 member 7 transporter
Probenecid Solute carrier family 22 member 6 target
Probenecid Pannexin-1 target
Probenecid Cytochrome P450 2C8 enzyme
Probenecid Cytochrome P450 3A4 enzyme
Probenecid Solute carrier family 22 member 12 transporter
Probenecid Solute carrier family 2, facilitated glucose transporter member 9 transporter
Probenecid Taste receptor type 2 member 16 target
Probenecid Cytochrome P450 2C9 enzyme
Probenecid UDP-glucuronosyltransferase 1A1 enzyme
Propofol Cytochrome P450 2B6 enzyme
Propofol ATP-dependent translocase ABCB1 transporter
Propofol GABA(A) Receptor target
Propofol UDP-glucuronosyltransferase 1A6 enzyme
Propofol Cytochrome P450 2C8 enzyme
Propofol Cytochrome P450 2C19 enzyme
Propofol Cytochrome P450 2C18 enzyme
Propofol Cytochrome P450 1A2 enzyme
Propofol Cytochrome P450 1A1 enzyme
Propofol Cytochrome P450 1B1 enzyme
Propofol Cytochrome P450 2E1 enzyme
Propofol UDP-glucuronosyltransferase 1A8 enzyme
Propofol Cytochrome P450 2C9 enzyme
Propofol Fatty-acid amide hydrolase 1 enzyme
Propofol Sodium channel protein type 2 subunit alpha target
Propofol Sodium channel protein type 4 subunit alpha target
Propofol Albumin carrier
Propofol Gamma-aminobutyric acid receptor subunit beta-3 target
Propofol Gamma-aminobutyric acid receptor subunit beta-2 target
Propofol UDP-glucuronosyltransferase 1A9 enzyme
Propofol UDP-glucuronosyltransferase 1A1 enzyme
Quizartinib Receptor-type tyrosine-protein kinase FLT3 target
Quizartinib Mast/stem cell growth factor receptor Kit target
Quizartinib Cytochrome P450 3A5 enzyme
Quizartinib UDP-glucuronosyltransferase 1A1 enzyme
Quizartinib ATP-dependent translocase ABCB1 transporter
Quizartinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Quizartinib Albumin carrier
Quizartinib Cytochrome P450 3A7 enzyme
Quizartinib Macrophage colony-stimulating factor 1 receptor target
Quizartinib Proto-oncogene tyrosine-protein kinase receptor Ret target
Quizartinib Cytochrome P450 3A4 enzyme
Regorafenib Vascular endothelial growth factor receptor target
Regorafenib Macrophage colony-stimulating factor 1 receptor target
Regorafenib Cytochrome P450 2C19 enzyme
Regorafenib UDP-glucuronosyltransferase 1A1 enzyme
Regorafenib Cytochrome P450 3A4 enzyme
Regorafenib UDP-glucuronosyltransferase 1A9 enzyme
Regorafenib Proto-oncogene tyrosine-protein kinase receptor Ret target
Regorafenib Vascular endothelial growth factor receptor 1 target
Regorafenib Vascular endothelial growth factor receptor 2 target
Regorafenib Vascular endothelial growth factor receptor 3 target
Regorafenib Mast/stem cell growth factor receptor Kit target
Regorafenib Platelet-derived growth factor receptor alpha target
Regorafenib Platelet-derived growth factor receptor beta target
Regorafenib Fibroblast growth factor receptor 1 target
Regorafenib Fibroblast growth factor receptor 2 target
Regorafenib Angiopoietin-1 receptor target
Regorafenib Discoidin domain-containing receptor 2 target
Regorafenib High affinity nerve growth factor receptor target
Regorafenib Ephrin type-A receptor 2 target
Regorafenib RAF proto-oncogene serine/threonine-protein kinase target
Regorafenib Serine/threonine-protein kinase B-raf target
Regorafenib Cytochrome P450 2C8 enzyme
Regorafenib Cytochrome P450 2C9 enzyme
Regorafenib Cytochrome P450 2B6 enzyme
Regorafenib Tyrosine-protein kinase FRK target
Regorafenib Tyrosine-protein kinase ABL1 target
Regorafenib ATP-dependent translocase ABCB1 transporter
Regorafenib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Regorafenib Mitogen-activated protein kinase 11 target
Repotrectinib UDP-glucuronosyltransferase 1A1 enzyme
Repotrectinib Cytochrome P450 3A5 enzyme
Repotrectinib Cytochrome P450 2C9 enzyme
Repotrectinib Cytochrome P450 2C19 enzyme
Repotrectinib Cytochrome P450 2C8 enzyme
Repotrectinib Cytochrome P450 2B6 enzyme
Repotrectinib Multidrug and toxin extrusion protein 2 transporter
Repotrectinib Solute carrier organic anion transporter family member 1B1 transporter
Repotrectinib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Repotrectinib ATP-dependent translocase ABCB1 transporter
Repotrectinib Cytochrome P450 3A4 enzyme
Repotrectinib NT-3 growth factor receptor target
Repotrectinib BDNF/NT-3 growth factors receptor target
Repotrectinib High affinity nerve growth factor receptor target
Repotrectinib Proto-oncogene tyrosine-protein kinase ROS target
Rucaparib Cytochrome P450 3A5 enzyme
Rucaparib Organic anion transporter 3 transporter
Rucaparib Solute carrier family 22 member 6 transporter
Rucaparib Solute carrier organic anion transporter family member 1B3 transporter
Rucaparib Cytochrome P450 3A7 enzyme
Rucaparib ATP-binding cassette sub-family C member 4 transporter
Rucaparib Solute carrier family 22 member 1 transporter
Rucaparib Multidrug and toxin extrusion protein 2 transporter
Rucaparib Multidrug and toxin extrusion protein 1 transporter
Rucaparib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Rucaparib ATP-dependent translocase ABCB1 transporter
Rucaparib Cytochrome P450 3A4 enzyme
Rucaparib Cytochrome P450 1A2 enzyme
Rucaparib Cytochrome P450 2D6 enzyme
Rucaparib Protein mono-ADP-ribosyltransferase PARP3 target
Rucaparib Poly [ADP-ribose] polymerase 2 target
Rucaparib Poly [ADP-ribose] polymerase 1 target
Rucaparib Cytochrome P450 3A43 enzyme
Rucaparib Cytochrome P450 2C19 enzyme
Rucaparib Cytochrome P450 2C9 enzyme
Rucaparib Cytochrome P450 2C8 enzyme
Rucaparib UDP-glucuronosyltransferase 1A1 enzyme
Rucaparib Poly [ADP-ribose] polymerases target
Rucaparib Solute carrier organic anion transporter family member 1B1 transporter
Silibinin Solute carrier family 22 member 6 transporter
Silibinin UDP-glucuronosyltransferase 1A1 enzyme
Silibinin Solute carrier organic anion transporter family member 1B1 transporter
Silibinin Solute carrier organic anion transporter family member 1B3 transporter
Silibinin Solute carrier organic anion transporter family member 2B1 transporter
Silibinin Polyunsaturated fatty acid 5-lipoxygenase target
Sodium aurothiomalate Protein kinase C iota type target
Sodium aurothiomalate Albumin carrier
Sodium aurothiomalate UDP-glucuronosyltransferase 1A1 enzyme
Sorafenib Proto-oncogene tyrosine-protein kinase receptor Ret target
Sorafenib Solute carrier organic anion transporter family member 1B1 transporter
Sorafenib Epidermal growth factor receptor target
Sorafenib Vascular endothelial growth factor receptor target
Sorafenib Fibroblast growth factor receptor 1 target
Sorafenib RalA-binding protein 1 transporter
Sorafenib UDP-glucuronosyltransferase 1A1 enzyme
Sorafenib Cytochrome P450 2D6 enzyme
Sorafenib Cytochrome P450 2C19 enzyme
Sorafenib Cytochrome P450 1A2 enzyme
Sorafenib Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Sorafenib ATP-binding cassette sub-family C member 2 transporter
Sorafenib ATP-dependent translocase ABCB1 transporter
Sorafenib ATP-binding cassette sub-family C member 4 transporter
Sorafenib Cytochrome P450 2C9 enzyme
Sorafenib Cytochrome P450 3A7 enzyme
Sorafenib Cytochrome P450 3A5 enzyme
Sorafenib Cytochrome P450 2C8 enzyme
Sorafenib Cytochrome P450 2B6 enzyme
Sorafenib UDP-glucuronosyltransferase 1A9 enzyme
Sorafenib Cytochrome P450 3A4 enzyme
Sorafenib Vascular endothelial growth factor receptor 2 target
Sorafenib Mast/stem cell growth factor receptor Kit target
Sorafenib Platelet-derived growth factor receptor beta target
Sorafenib Vascular endothelial growth factor receptor 3 target
Sorafenib RAF proto-oncogene serine/threonine-protein kinase target
Sorafenib Receptor-type tyrosine-protein kinase FLT3 target
Sorafenib Serine/threonine-protein kinase B-raf target
Sorafenib Vascular endothelial growth factor receptor 1 target
Ubrogepant Solute carrier family 22 member 6 transporter
Ubrogepant ATP-dependent translocase ABCB1 transporter
Ubrogepant Broad substrate specificity ATP-binding cassette transporter ABCG2 transporter
Ubrogepant Cytochrome P450 3A4 enzyme
Ubrogepant Cytochrome P450 2C8 enzyme
Ubrogepant Solute carrier organic anion transporter family member 1B3 transporter
Ubrogepant Cytochrome P450 2D6 enzyme
Ubrogepant Cytochrome P450 2C19 enzyme
Ubrogepant Amine oxidase [flavin-containing] A enzyme
Ubrogepant UDP-glucuronosyltransferase 1A1 enzyme
Ubrogepant Solute carrier organic anion transporter family member 1B1 transporter
Ubrogepant Calcitonin gene-related peptide type 1 receptor target
Ubrogepant Solute carrier family 22 member 2 transporter
Ubrogepant Cytochrome P450 2C9 enzyme
Valproic acid Prostaglandin G/H synthase 1 enzyme
Valproic acid Organic cation/carnitine transporter 2 transporter
Valproic acid Solute carrier family 22 member 6 transporter
Valproic acid Organic anion transporter 3 transporter
Valproic acid Monocarboxylate transporter 1 transporter
Valproic acid Solute carrier family 22 member 7 transporter
Valproic acid Cytochrome P450 3A5 enzyme
Valproic acid Glycogen synthase kinase-3 alpha target
Valproic acid 4-aminobutyrate aminotransferase, mitochondrial target
Valproic acid Programmed cell death 1 ligand 1 target
Valproic acid Ornithine decarboxylase target
Valproic acid Hepatocyte growth factor target
Valproic acid Cyclin-dependent kinase inhibitor 1 target
Valproic acid Histone deacetylase target
Valproic acid Solute carrier organic anion transporter family member 2B1 transporter
Valproic acid UDP-glucuronosyltransferase 1A1 enzyme
Valproic acid Albumin carrier
Valproic acid Peroxisome proliferator-activated receptor gamma target
Valproic acid Peroxisome proliferator-activated receptor delta target
Valproic acid Peroxisome proliferator-activated receptor alpha target
Valproic acid Histone deacetylase 2 target
Valproic acid Sodium channel protein target
Valproic acid Succinate-semialdehyde dehydrogenase, mitochondrial target
Valproic acid 2-oxoglutarate dehydrogenase complex component E1 target
Valproic acid UDP-glucuronosyltransferase 2B15 enzyme
Valproic acid UDP-glucuronosyltransferase 2B7 enzyme
Valproic acid UDP-glucuronosyltransferase 1A3 enzyme
Valproic acid UDP-glucuronosyltransferase 1A6 enzyme
Valproic acid UDP-glucuronosyltransferase 1A10 enzyme
Valproic acid UDP-glucuronosyltransferase 1A8 enzyme
Valproic acid UDP-glucuronosyltransferase 1A4 enzyme
Valproic acid Cytochrome P450 3A4 enzyme
Valproic acid Cytochrome P450 2C19 enzyme
Valproic acid UDP-glucuronosyltransferase 1A9 enzyme
Valproic acid Cytochrome P450 2C9 enzyme
Valproic acid Cytochrome P450 2B6 enzyme
Valproic acid Cytochrome P450 2A6 enzyme
Valproic acid Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial target
Valproic acid Histone deacetylase 9 target
Valproic acid Cytochrome P450 1A2 enzyme

Drug	Drug Description
Adenine	A purine base which forms a component of DNA among other functions and is present in many multivitamins.
Almonertinib	A third-generation, irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) indicated for the treatment of patients with metastatic EGFR T790M mutation-positive non-small cell lung cancer (NSCLC).
Amitriptyline	A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
Aprocitentan	An endothelin receptor antagonist used for the treatment of uncontrolled hypertension in patients inadequately controlled on other treatments.
Asciminib	An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation.
Atazanavir	An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Belumosudil	An oral inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK) used in the treatment of chronic graft-versus-host disease (GVHD).
Dabrafenib	A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Dacomitinib	A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
Dasabuvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
Defactinib	An inhibitor of FAK used alongside a MEK1/RAF inhibitor for the treatment of recurrent low-grade serous ovarian cancer.
Deferasirox	An iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
Eltrombopag	A thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Enasidenib	An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Encorafenib	A kinase inhibitor used to treat unresectable or metastatic melanoma with BRAF mutations.
Erlotinib	An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Ertugliflozin	An SGLT2 inhibitor used to treat type 2 diabetes mellitus alone or in combination with other antidiabetic drugs.
Flunitrazepam	A benzodiazepine used to manage anxiety disorders and insomnia.
Flurbiprofen	An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Fostamatinib	A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
Gemfibrozil	A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
Glecaprevir	A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
Indinavir	A protease inhibitor used to treat HIV infection.
Indomethacin	A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Ketoconazole	A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
Lazertinib	A tyrosine kinase inhibitor used in combiantion with amivantamab to treat non-small cell lung cancer with EGFR mutations.
Momelotinib	A Janus Kinase inhibitor used to treat intermediate or high-risk myelofibrosis.
Nilotinib	A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
Olaparib	A poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Ombitasvir	A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Osilodrostat	An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Paltusotine	A somatostatin receptor agonist used to treat acromegaly in adults whose surgery is not an option or has not been effective.
Paritaprevir	A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Pazopanib	An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
Pexidartinib	An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
Pibrentasvir	A Hepatitis C NS5A inhibitor used to treat Hepatitis C.
Probenecid	A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Propofol	A medication used in general anesthesia and for sedation.
Quizartinib	A FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication
Regorafenib	A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.

UGT1A1 Inhibitors

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