Benzodiazepine hypnotics and sedatives
- Benzodiazepine hypnotics and sedatives
- Accession Number
Benzodiazepines can be useful for short-term treatment of insomnia. Their use beyond 2 to 4 weeks is not recommended due to the risk of dependence. It is preferred that benzodiazepines be taken intermittently and at the lowest effective dose. They improve sleep-related problems by shortening the time spent in bed before falling asleep, prolonging the sleep time, and, in general, reducing wakefulness. Their mechanism of action is primarily at GABAA receptors.
Drug Drug Description Bromazepam A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Brotizolam A benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia. Cinolazepam A benzodiazepine used to manage severe and debilitating forms of sleep disorders of various origins in adults. Estazolam A benzodiazepine used for the short-term management of insomnia. Etizolam A thienodiazepine derivative used to treat anxiety and insomnia. Flunitrazepam A benzodiazepine used to manage anxiety disorders and insomnia. Loprazolam Loprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent... Lorazepam A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. Midazolam A short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Nitrazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. Quazepam A long -acting benzodiazepine used to manage insomnia. Temazepam A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia. Triazolam A benzodiazepine used for short term treatment of insomnia. Eszopiclone A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Zaleplon A sedative used for short term treatment of insomnia in adults. Zolpidem A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Zopiclone A nonbenzodiazepine hypnotic used for the short-term management of insomnia. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Oxazepam An intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia. Medazepam A long-acting benzodiazepine used for its sedative and anxiolytic properties. Remimazolam An ultra short-acting benzodiazepine used for the induction and maintenence of procedural sedation during short procedures.
- Drugs & Drug Targets