Hypnotics and Sedatives
- Name
- Hypnotics and Sedatives
- Accession Number
- DBCAT000452
- Description
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
- ATC Classification
- Drugs
Drug Drug Description Acecarbromal Acecarbromal is a small molecule drug. Acecarbromal has a monoisotopic molecular weight of 278.03 Da. Acetylglycinamide chloral hydrate Not Annotated Allobarbital Not Annotated Alprazolam A triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. Amobarbital A barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures. Aprobarbital Aprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment... Apronalide Apronalide is approved in Japan. Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura . Azaperone Azaperone is a pyridinylpiperazine and butyrophenone agent that is capable of eliciting neuroleptic sedative and antiemetic effects. It is subsequently employed predominantly as a veterinary tranquilizer and mainly for pigs... AZD-3043 AZD3043 has been used in trials studying the treatment and basic science of Safety, Sedation, Tolerability, and Pharmacokinetics. Barbital A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice... Bentazepam Not Annotated Bromazepam A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Bromisoval Not Annotated Brotizolam A benzodiazepine analogue with sedative-hypnotic properties used for short-term treatment of severe or debilitating insomnia. Butabarbital A barbiturate drug used as a sedative and hypnotic. Butalbital A barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine. Butobarbital For the treatment of insomnia. Carbromal Not Annotated Chloral hydrate A mild hypnotic used for experimental purposes that was previously used for the treatment of insomnia. Chloralose Chloralose is a small molecule drug. Chloralose has a monoisotopic molecular weight of 307.96 Da. Chlordiazepoxide A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. Chlorhexadol Chlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate. Cinolazepam A benzodiazepine used to manage severe and debilitating forms of sleep disorders of various origins in adults. Cipepofol An alkylphenol GABA-A positive allosteric modulator used for induction of general anesthesia in adults undergoing surgery. Clomethiazole Investigated for use/treatment in strokes. CP-96345 Not Annotated Cyclobarbital Not Annotated Daridorexant A dual orexin receptor antagonist used to treat insomnia in adults. Detomidine Used as a large animal sedative, primarily in horses. Dexmedetomidine An alpha-2 agonist used for sedation during various procedures. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Dichloralphenazone Dichloralphenazone is a sedative composed of chloral hydrate and phenazone. It is typically found in combination products Nodolor and Midrin containing isometheptene and acetaminophen used for the relief of tension... Diphenhydramine A H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes. Doxefazepam Not Annotated Doxepin A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. Emepronium Not Annotated Estazolam A benzodiazepine used for the short-term management of insomnia. Eszopiclone A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Ethchlorvynol A sedative hypnotic agent used for the short-term management of insomnia. Etizolam A thienodiazepine derivative used to treat anxiety and insomnia. Etomidate A short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Fluanisone Not Annotated Flunitrazepam A benzodiazepine used to manage anxiety disorders and insomnia. Flurazepam A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. Fospropofol A sedative-hypnotic agent indicated for monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures. Gedocarnil Not Annotated Glutethimide For the treatment of insomnia. Heptabarbital Used mainly for sedation and hypnosis. Hexapropymate Not Annotated Hexobarbital For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... Indiplon Indiplon has been used in trials studying the treatment of Insomnia and Depression. Lemborexant A dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. Loprazolam Loprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent... Lorazepam A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. Lormetazepam A benzodiazepine indicated in the treatment of anxiety and the induction of anesthesia. Medazepam A long-acting benzodiazepine used for its sedative and anxiolytic properties. Medetomidine Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist.... Melatonin An endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement. Meprobamate An anxiolytic drug used for the short-term management of anxiety symptoms. Mepyramine An antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. Methapyrilene Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. Methaqualone For the treatment of insomnia, and as a sedative and muscle relaxant. Methohexital An anesthetic used to induce deep sedation. Methylpentynol Not Annotated Methylphenobarbital For the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy. Methyprylon For the treatment of insomnia. Midazolam A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Niaprazine Niaprazine is a selective brain catecholamine depletor. Nitrazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. Ocinaplon Investigated for use/treatment in anxiety disorders. Oxazepam An intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia. Pagoclone For the potential treatment of panic and anxiety disorders. Paraldehyde A central nervous system depressant previously used to control convulsions due to various clinical causes, including tetanus, status epilepticus, and convulsive drugs. Passiflora incarnata flower A herbal product indicated in the treatment of stress, nervousness, anxiety, irritability, and trouble sleeping. Pentobarbital A barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures. Phenibut Not Annotated Phenobarbital A long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures. Phetharbital Phetharbital is a small molecule drug. Phetharbital has a monoisotopic molecular weight of 260.12 Da. Primidone An antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures. Propiomazine Propiomazine is largely used for its antihistamininc sleep inducing effects in treating insomnia. Propofol A medication used in general anesthesia and for sedation. Proxibarbal Proxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing... Pyrazolam Not Annotated Pyrithyldione Not Annotated Quazepam A long-acting benzodiazepine used to manage insomnia. Ramelteon A melatonin receptor agonist used to treat insomnia. Remifentanil An opioid analgesic used in anesthesia. Remimazolam An ultra short-acting benzodiazepine used for the induction and maintenence of procedural sedation during short procedures. Reposal Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. Rilmazafone Rilmazafone is a small molecule drug. The usage of the INN stem '-zafone' in the name indicates that Rilmazafone is a alozafone derivative. Rilmazafone has a monoisotopic molecular weight of... Romifidine Romifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species.... S-Ethylisothiourea S-Ethylisothiourea is a nitric oxide synthase inhibitor. Scopolamine A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). Secobarbital A barbiturate used for the short-term treatment of insomnia. Suvorexant A orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. Talbutal For use as a sedative and hypnotic. Tasimelteon A melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder. Temazepam A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia. Thiamylal Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. Thiopental A barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure. Triazolam A benzodiazepine used for short term treatment of insomnia. Triclofos Not Annotated Valerian A plant used in some non-prescription natural health products. Valnoctamide Valnoctamide has been used in trials studying the treatment of Mania and Schizoaffective Disorder, Manic Type. Vinbarbital Not Annotated Vinylbital Not Annotated Xylazine A non-opioid and clonidine analog with analgesic and muscle relaxant properties used as a tranquilizer used in veterinary medicine. Zaleplon A sedative used for short term treatment of insomnia in adults. Zolpidem A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Zopiclone A nonbenzodiazepine hypnotic used for the short-term management of insomnia.