Monoamine Oxidase A Substrates

Name
Monoamine Oxidase A Substrates
Accession Number
DBCAT004538
Description

Drugs that are metabolized either partially or completely by Monoamine Oxidase A (MAO-A) enzyme.

Drugs
DrugDrug Description
RizatriptanA 5-HT1B/1D receptor agonist used to treat migraines.
SumatriptanA serotonin receptor agonist used to treat migraines and cluster headaches.
AlmotriptanA 5-HT1B/1D receptor agonist used to treat migraines.
ZolmitriptanA member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults.
NaratriptanA 5-HT1B/1D receptor agonist used to treat migraines.
PhenylephrineAn alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
PhenelzineA monoamine oxidase inhibitor used to treat atypical, nonendogenous, or neurotic depression.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
EravacyclineA tetracycline antibiotic used to treat complicated intra-abdominal infections.
BufotenineA hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a...
BicifadineFor the treatment of pain.
SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
Drugs & Drug Targets
DrugTargetType
Rizatriptan5-hydroxytryptamine receptor 1Dtarget
Rizatriptan5-hydroxytryptamine receptor 1Btarget
Rizatriptan5-hydroxytryptamine receptor 1Ftarget
RizatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Dtarget
Sumatriptan5-hydroxytryptamine receptor 1Btarget
Sumatriptan5-hydroxytryptamine receptor 1Ftarget
SumatriptanAmine oxidase [flavin-containing] Aenzyme
Sumatriptan5-hydroxytryptamine receptor 1Atarget
SumatriptanSolute carrier organic anion transporter family member 1A2transporter
SumatriptanP-glycoprotein 1transporter
SumatriptanATP-binding cassette sub-family G member 2transporter
SumatriptanSolute carrier organic anion transporter family member 1B1transporter
Almotriptan5-hydroxytryptamine receptor 1Dtarget
Almotriptan5-hydroxytryptamine receptor 1Btarget
AlmotriptanCytochrome P450 3A4enzyme
AlmotriptanCytochrome P450 2D6enzyme
AlmotriptanAmine oxidase [flavin-containing] Aenzyme
AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
AlmotriptanCytochrome P450 2C19enzyme
AlmotriptanCytochrome P450 2E1enzyme
AlmotriptanCytochrome P450 2C8enzyme
Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
Zolmitriptan5-hydroxytryptamine receptor 1Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
ZolmitriptanCytochrome P450 1A2enzyme
ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
Zolmitriptan5-hydroxytryptamine receptor 1Atarget
ZolmitriptanP-glycoprotein 1transporter
Zolmitriptan5-hydroxytryptamine receptor 7target
Zolmitriptan5-hydroxytryptamine receptor 2Atarget
Zolmitriptan5-hydroxytryptamine receptor 2Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Etarget
Naratriptan5-hydroxytryptamine receptor 1Dtarget
Naratriptan5-hydroxytryptamine receptor 1Btarget
Naratriptan5-hydroxytryptamine receptor 1Ftarget
Naratriptan5-hydroxytryptamine receptor 1Atarget
NaratriptanAmine oxidase [flavin-containing] Aenzyme
PhenylephrineAlpha-1A adrenergic receptortarget
PhenylephrineAlpha-1B adrenergic receptortarget
PhenylephrineAmine oxidase [flavin-containing] Aenzyme
PhenylephrineAlpha-1D adrenergic receptortarget
PhenylephrineCytochrome P450 1A2enzyme
PhenylephrineSulfotransferase 1A3/1A4enzyme
PhenylephrineAmine oxidase [flavin-containing] Benzyme
PhenelzineMembrane primary amine oxidasetarget
PhenelzineAmine oxidase [flavin-containing] Btarget
PhenelzineAmine oxidase [flavin-containing] Atarget
PhenelzineAmine oxidase [flavin-containing] Aenzyme
PhenelzineAmine oxidase [flavin-containing] Benzyme
PhenelzineCytochrome P450 2E1enzyme
Phenelzine4-aminobutyrate aminotransferase, mitochondrialtarget
PhenelzineGlutamic acid decarboxylasetarget
PhenelzineAlanine aminotransferase 1target
PhenelzineAlanine aminotransferase 2target
PhenelzineCytochrome P450 2C19enzyme
PhenelzineCytochrome P450 2C8enzyme
PhenelzineCytochrome P450 3A4enzyme
PhenelzineCytochrome P450 3A5enzyme
PhenelzineCytochrome P450 3A7enzyme
PhenelzineCytochrome P450 2D6enzyme
PhenelzineCytochrome P450 3A Subfamilyenzyme
DopamineDopamine D1 receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineSolute carrier family 22 member 5transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineDopamine D5 receptortarget
DopamineDopamine D2 receptortarget
DopamineDopamine D3 receptortarget
DopamineDopamine D4 receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
EravacyclineCytochrome P450 3A4enzyme
EravacyclineAmine oxidase [flavin-containing] Aenzyme
Eravacycline30S ribosomal protein S4target
BufotenineAmine oxidase [flavin-containing] Aenzyme
BicifadineSodium-dependent noradrenaline transportertarget
BicifadineSodium-dependent serotonin transportertarget
BicifadineDopamine D2 receptortarget
BicifadineCytochrome P450 2D6enzyme
BicifadineAmine oxidase [flavin-containing] Benzyme
BicifadineCytochrome P450 1A2enzyme
BicifadineAmine oxidase [flavin-containing] Aenzyme
SertralineSodium-dependent serotonin transportertarget
SertralineCytochrome P450 2B6enzyme
SertralineCytochrome P450 2C19enzyme
SertralineCytochrome P450 2C9enzyme
SertralineCytochrome P450 2D6enzyme
SertralineSodium-dependent dopamine transportertarget
SertralineCYP2B proteinenzyme
SertralineCytochrome P450 3A4enzyme
SertralineAmine oxidase [flavin-containing] Benzyme
SertralineAmine oxidase [flavin-containing] Aenzyme
SertralineP-glycoprotein 1transporter
SertralineSerum albumincarrier
SertralineSigma receptortarget
SertralineSodium-dependent noradrenaline transportertarget
SertralineEquilibrative nucleoside transporter 4target
SertralineCytochrome P450 2E1enzyme