Serotonin 5-HT1 Receptor Agonists
- Name
- Serotonin 5-HT1 Receptor Agonists
- Accession Number
- DBCAT000734
- Description
Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes.
- Drugs
Drug Drug Description 5-methoxy-N,N-dimethyltryptamine 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,... Almotriptan A 5-HT1B/1D receptor agonist used to treat migraines. Aripiprazole An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. Befiradol Befiradol is under investigation in clinical trial NCT05148884 (Study to Assess the Safety, Tolerability and Preliminary Efficacy of NLX-112 Versus Placebo in L-dopa-induced Dyskinesia). Brexpiprazole A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct, schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. Cabergoline A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. Cannabidiol An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. Cariprazine An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. Cinitapride A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying. Dihydroergotamine An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. Eletriptan A triptan used for the treatment of migraines. Ergotamine An alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. F-15599 Not Annotated Flibanserin A 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). Frovatriptan A 5-HT1B/1D receptor agonist used to treat migraines. Lisuride For the management of Parkinson's Disease Naluzotan Investigated for use/treatment in anxiety disorders and depression. Naratriptan A 5-HT1B/1D receptor agonist used to treat migraines. Piclozotan Piclozotan has been investigated for the treatment of Parkinson's Disease. Rizatriptan A triptan used to treat migraines with or without aura. Rotigotine A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Tetrahydrocannabivarin THCV does not currently have any FDA, Health Canada, or EMA approved indications. Vilazodone An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. Vortioxetine A serotonin modulating antidepressant indicated for the treatment of major depressive disorder (MDD). Ziprasidone An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. Zolmitriptan A member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults. - Drugs & Drug Targets