Chancroid (DBCOND0001290)

Identifiers

Synonyms

Ulcus molle / Hemophilus ducreyi chancroid / Chancroid (disorder) / Haemophilus ducreyi infection / Hemophilus ducreyi infection / Haemophilus ducreyi chancroid

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Acetyl sulfisoxazole	Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the...	Dihydropteroate synthasetarget Cytochrome P450 2C9enzyme
Azithromycin	A macrolide antibiotic used to treat a variety of bacterial infections.	23S ribosomal RNAtarget ATP-dependent translocase ABCB1transporter Cytochrome P450 3A4enzyme Protein-arginine deiminase type-4target ATP-binding cassette sub-family C member 2transporter
Ceftriaxone	A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.	Albumincarrier Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Penicillin-binding protein 2Btarget Glutamine synthetaseenzyme Solute carrier family 22 member 11target Solute carrier family 22 member 6target Organic anion transporter 3target Solute carrier family 15 member 1target ATP-dependent translocase ABCB1transporter
Doxycycline	A tetracycline antibiotic used to treat a wide variety of bacterial infections.	Solute carrier family 22 member 6transporter Cytochrome P450 3A4enzyme ATP-binding cassette sub-family B member 5transporter Albumincarrier 30S ribosomal proteintarget
Erythromycin	A macrolide antibiotic used to treat and prevent a variety of bacterial infections.	23S ribosomal RNAtarget Cytochrome P450 3A4enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Solute carrier organic anion transporter family member 1B1transporter Motilin receptortarget Voltage-gated inwardly rectifying potassium channel KCNH2target Cytochrome P450 3A5enzyme Solute carrier organic anion transporter family member 1B3transporter Bile salt export pumptransporter ATP-binding cassette sub-family C member 2transporter Solute carrier organic anion transporter family member 1A2transporter
Minocycline	A tetracycline analog used to treat a wide variety of infections in the body.	30S ribosomal protein S4target 30S ribosomal protein S9target 16S ribosomal RNAtarget Interleukin-1 betatarget Polyunsaturated fatty acid 5-lipoxygenasetarget Matrix metalloproteinase-9target Vascular endothelial growth factor A, long formtarget Caspase-1target Caspase-3target Cytochrome ctarget Solute carrier family 22 member 6transporter Solute carrier family 22 member 7transporter Outer membrane protein Ftransporter Outer membrane porin Ctransporter Mitogen-activated Protein Kinasestarget Nitric oxide synthase, inducibletarget
Streptomycin	An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.	30S ribosomal protein S12target 16S ribosomal RNAtarget Protein-arginine deiminase type-4target 23S ribosomal RNAtarget Bacterial outer membranetarget Cytoplasmic membranetarget
Sulfadiazine	A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.	Cytochrome P450 2C9enzyme Dihydropteroate synthetasetarget Cytochrome P450 2C8enzyme Cytochrome P450 3A4enzyme Dihydropteroate synthasetarget
Tetracycline	An antibiotic used to treat a wide variety of susceptible infections.	16S ribosomal RNAtarget Major prion proteintarget Albumincarrier Cytochrome P450 3A4enzyme Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier family 22 member 7transporter 30S ribosomal protein S3target 30S ribosomal protein S8target 30S ribosomal protein S19target 30S ribosomal protein S14target 30S ribosomal protein S7target Multidrug translocase MdfAtarget Protein-arginine deiminase type-4target Solute carrier organic anion transporter family member 2B1transporter

Clinical Trials

Not Available