Herpes Simplex (DBCOND0027882)

Identifiers

Synonyms
Herpes simplex / Herpesviral infection, unspecified / Herpes simplex (disorder) / HSV infection / Herpesviral [herpes simplex] infections / Herpes simplex NOS

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Lysozyme
An enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04065971
Randomized, Placebo-controlled, Double-blind Study of 2LHERPĀ® in Orofacial Herpes Infections.No drug interventionstreatment4recruiting
NCT05468619
Neonatal Phase 1 Valacyclovir Studyprevention1recruiting
NCT01959295
Phase III Study of ASP2151 in Herpes Simplex Patientstreatment3completed
NCT00002084
A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected PatientstreatmentNot Availablecompleted
NCT00224484
Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Oldprevention3completed
NCT00001054
The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected Childrentreatment1withdrawn
NCT05298254
A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital HerpesNo drug interventionstreatment1 / 2active_not_recruiting
NCT00530777
HSV-2 Suppression to Reduce Maternal HIV-1 RNA Levels During Pregnancy and Breastfeedingtreatment2completed
NCT00031447
Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and Mouthtreatment3completed
NCT02349828
Antiviral Prophylaxis in a Burn Populationtreatment2 / 3withdrawn
NCT00642785
Activation of Alternative Cellular Energy (ACE) Pathway in the Therapy of Herpes Virus InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00001115
The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the BloodtreatmentNot Availablecompleted
NCT00194415
A Study of HSV Testing Among Pregnant WomenNo drug interventionspreventionNot Availableterminated
NCT00098059
Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex Infectiontreatment3completed
NCT00297206
A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Childrentreatment1completed
NCT00001649
Valaciclovir to Prevent Transmission of Herpes Simplex Virustreatment3completed
NCT00161434
A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Personsprevention4completed
NCT02209324
Open-label Study of ASP2151 in Herpes Simplex Patientstreatment3completed
NCT00002116
A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDStreatment1completed
NCT00000635
Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical TrifluridinetreatmentNot Availablecompleted
NCT00138320
Herpevac Neonatal SubstudyNo drug interventionsNot AvailableNot Availableterminated
NCT00448227
Pharmacokinetics, Acceptability and Safety of Famciclovir in Infants (1 Month to Less Than 12 Months) With Herpes Simplex Infectiontreatment2completed
NCT06134492
Acyclovir in Mechanically Ventilated Patients With Pneumonia and HSV-1 in BALtreatment3recruiting
NCT00002181
Cidofovir as a Treatment for Herpes Simplex in Patients With AIDStreatmentNot Availablecompleted
NCT00699764
Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes DiseaseNo drug interventionsprevention3completed
NCT04239521
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataNo drug interventionsNot AvailableNot Availablecompleted
NCT00002021
An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other ImmunodeficienciestreatmentNot Availablecompleted
NCT00000654
The Tolerance of HIV-Infected Patients With Herpes Group Virus Infections to Oral Doses of FIAUtreatment2completed
NCT03178747
Tzanck Smear With Methylene Blue Stain for HerpesNo drug interventionsdiagnostic3unknown_status
NCT00465205
HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Personsprevention3completed
NCT01794897
Valacyclovir Augmentation for Cognitive and Functional Remediation in Schizophreniabasic_science4completed
NCT04762511
A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 YearsNo drug interventionstreatment1terminated
NCT00698893
Evaluation of Safety of Candidate gD Vaccine, With or Without MPL in Healthy Herpes Simplex Virus-positive AdultsNo drug interventionsprevention1completed
NCT00224471
Study to Compare Safety and Immunogenicity of Commercial Scale Consistency Lots of Herpes Simplex VaccineNo drug interventionsprevention3completed
NCT00855309
Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropeniasupportive_care3completed
NCT01176409
Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?treatment3completed
NCT02685956
Clinical Evaluation of the Sentosa SA HSV1/2 Qualitative PCR TestNo drug interventionsNot AvailableNot Availablecompleted
NCT00000985
Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With Acyclovirtreatment3completed
NCT00006132
Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous Systemtreatment3unknown_status
NCT00002000
A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected PatientstreatmentNot Availablecompleted
NCT00164424
Episodic Acyclovir Therapy for Genital Ulcerstreatment2 / 3completed
NCT00587496
30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteersprevention1unknown_status
NCT00006135
Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Limited to Skin, Eyes, and Mouthtreatment3completed
NCT00985335
Effectiveness of TheraNeem Lip Therapy for Herpes Simplex LabialisNo drug interventionstreatment1completed
NCT00005663
A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patientstreatment3unknown_status
NCT00002186
Double-Blind Placebo-Controlled Study Comparing the Combination of 15% SP-303 Gel With Acyclovir Versus Acyclovir Alone for the Treatment of Recurrent Herpes Simplex Virus (HSV) Infections in Subjects With Acquired Immunodeficiency Syndrome (AIDS)treatmentNot Availablecompleted
NCT00000139
Herpetic Eye Disease Study (HEDS) IItreatment3completed
NCT00001648
Structure of the Herpes Simplex Virus ReceptorNo drug interventionsNot AvailableNot Availablecompleted
NCT00004757
Phase III Randomized, Placebo-Controlled Study of Acyclovir Oral Suspension for Neonatal Herpes Simplex Virus Infection Limited to the Skin, Eyes, and Mouthtreatment3completed
NCT00973466
Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02997982
Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Diseasetreatment2completed
NCT00213031
Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible MicrobicideNo drug interventionsother2completed
NCT04664127
Study of the Efficacy and Safety of Combined Treatment of Patients With Severe Herpes Simplex (HSV) Infection by Valacyclovir and Interferon Inducer KagocelNot AvailableNot Availablecompleted
NCT00378976
HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men.prevention3completed
NCT00031460
Acyclovir for Herpes Infections Involving the Central Nervous System in Neonatestreatment3completed
NCT01602562
Valaciclovir Hydrochloride Phase III for Hematopoietic Stem Cell Transplantation Patientsprevention3completed
NCT00004644
Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infectiontreatment1 / 2completed
NCT00002144
The Pilot Study of Foscarnet Cream in the Treatment of Mucocutaneous Herpes Simplex Virus Infections in Immunocompromised Patients Unresponsive to Acyclovir Treatmenttreatment1completed
NCT00002404
The Effect of Valacyclovir on the Detection of HIV From Genital Herpes Lesions in HIV-Infected PatientstreatmentNot Availablecompleted
NCT00002272
An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other ImmunodeficienciestreatmentNot Availablecompleted
NCT05989672
A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 YearsNo drug interventionstreatment1completed
NCT00002310
SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With AcyclovirtreatmentNot Availablecompleted