NCT06467474
Psychoeducational Group for Depression No drug interventions treatment Not Available recruiting NCT05416762
Single Dose Study to Evaluate Dose-proportionality of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets No drug interventions treatment 1 completed NCT05745194
Influence of Nutrition in Depression Treatment (INDEPT) No drug interventions treatment Not Available recruiting NCT00669110
Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder treatment 2 completed NCT04350567
Sleep/Wake Cycle and Depression: An Imaging and Treatment Study No drug interventions treatment Not Available recruiting NCT02213016
Effectiveness of Repetitive Transcranial Magnetic Stimulation in Depressed Patients No drug interventions treatment 4 unknown_status NCT00177996
Pharmacotherapy in Depression With Panic Spectrum treatment 4 completed NCT00944996
Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression basic_science Not Available completed NCT02594696
Proactive Psychiatry Consultation for Patients With Cancer and Severe Mental Illness No drug interventions health_services_research Not Available completed NCT00515658
Antidepressant Effect of Theta-Burst rTMS No drug interventions treatment 2 unknown_status NCT05608135
AI-based Multi-center Research on Identification/Classification/Aided Diagnosis of Mood Disorder No drug interventions Not Available Not Available recruiting NCT00566735
The Use of Galantamine HBr (Reminyl) in Electroconvulsive Therapy: Impact on Mood and Cognitive Functioning treatment 3 completed NCT01469663
Event Related Potentials in Borderline Personality Disorder and Major Depression No drug interventions Not Available Not Available terminated NCT00707863
Study of Brain Response to Emotional Pictures Using a Magnetic Resonance Imaging (fMRI) While on Escitalopram treatment 4 completed NCT00296686
Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression treatment 4 terminated NCT00249886
Discontinuation Study Of Citalopram (Antidepressant) in Depressed Adolescents treatment 3 withdrawn NCT04446039
Non-interventional, Retrospective Cohort Study to Explore Antidepressant Treatment in Korea Not Available Not Available completed NCT00291239
Effect of Partial Sleep Deprivation on Cognition and Cytokines in Individuals With Major Depression No drug interventions treatment 4 unknown_status NCT01153139
Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression No drug interventions treatment 2 / 3 completed NCT01667822
Cognitive Behavioral Therapy, Guided Self Help Versus Individual Therapy No drug interventions treatment 3 completed NCT04235725
Implementation of Harmonized Depression Outcome Measures in a Primary Care Registry and a Mental Health Registry No drug interventions Not Available Not Available completed NCT02253225
Self Focus in Bipolar Disorder: A Functional Magnetic Resonance Imaging (fMRI) Study No drug interventions Not Available Not Available completed NCT00296725
Dichotic Listening as a Predictor of Medication Response in Depression treatment 1 / 2 completed NCT01119430
Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder treatment 2 terminated NCT01201148
Open Pilot Trial of TES for Depression No drug interventions treatment 2 completed NCT00194948
Treatment Choices for Improving Adherence and Outcome treatment Not Available completed NCT01788657
iCBT for Depression - Standard Versus Condensed Treatment Material No drug interventions treatment Not Available completed NCT00541957
Randomized Trial of Psychotherapy for Persistently Depressed Primary Care Patients No drug interventions treatment 1 completed NCT01458626
Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement treatment 4 completed NCT00481026
A Double Blind Sham Controlled Trial of tDCS in Treating Schizophrenia and Depression No drug interventions treatment Not Available completed NCT00374426
Preventing Depression Recurrence in Diabetes treatment 4 completed NCT04872465
TBS Over DLPFC in Elderly Refractory Depression No drug interventions treatment Not Available recruiting NCT00844974
Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive Symptoms No drug interventions Not Available Not Available completed NCT00330174
Acamprosate in Alcoholics With Comorbid Anxiety or Depression treatment 4 completed NCT00105820
Evaluation Study of TIDES Depression Care Quality Improvement Intervention No drug interventions Not Available Not Available completed NCT02658682
Secondary Prevention of Depression Applying an Experimental Attentional Bias Modification Procedure No drug interventions prevention Not Available completed NCT00482482
Yoga in Unipolar and Bipolar Disorders No drug interventions treatment Not Available completed NCT01325831
Changes of Functional Connectivity After rTMS in Depression No drug interventions treatment 4 completed NCT01636791
CBT Versus a Return to Work Intervention for Patients With Common Mental Illness in Primary Care No drug interventions treatment 3 completed NCT00532480
Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine treatment 4 completed NCT00627029
Evaluation of Programs of Coordinated Care and Disease Management No drug interventions health_services_research Not Available unknown_status NCT05964192
Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment No drug interventions treatment Not Available recruiting NCT01124344
Safety and Pharmacology Study of BMS-866949 No drug interventions treatment 1 terminated NCT00579267
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) No drug interventions Not Available Not Available completed NCT00067301
PUFA Augmentation in Treatment of Major Depression treatment 3 completed NCT03156504
The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression. basic_science 4 completed NCT00300404
Effect of Specific Anti-Toxoplasmatic Add-on Medication in Toxoplasma Gondii Seropositive Individuals With Schizophrenia or Major Depression treatment 3 completed NCT05477472
Low Dose St John's Wort for Depression Not Available Not Available completed NCT00151372
Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients No drug interventions treatment Not Available completed NCT01132872
PET Whole Body Distribution Studies Using [11C]CUMI No drug interventions Not Available Not Available completed NCT00260468
Brain Abnormalities in Late-Onset Major Depression No drug interventions Not Available Not Available completed NCT02047968
Wake and Light Therapy to In-patients With Major Depression: Efficacy, Predictors and Patient Experiences No drug interventions treatment Not Available completed NCT01786746
Adapting Cognitive Behavioral Therapy (CBT) for Chinese Americans No drug interventions treatment Not Available completed NCT00159146
Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression treatment Not Available terminated NCT02890212
Selenium as Augmentation Treatment for Sertraline Resistant Major Depression No drug interventions treatment Not Available suspended NCT02085512
Prevention of PTSD III: Neurocognitive Training of Emotional Regulation No drug interventions prevention Not Available completed NCT00256412
Essential Fatty Acids for Major Depression treatment Not Available completed NCT05703412
Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness No drug interventions treatment Not Available enrolling_by_invitation NCT00447512
Effects of Ghrelin on the Sleep-EEG and Nocturnal Secretion of Hormones basic_science Not Available completed NCT01575912
Past Pain Experience and Perception of Experimental Pain No drug interventions Not Available Not Available completed NCT00296712
Are Two Antidepressants a Good Initial Treatment for Depression? treatment 4 completed NCT00149110
Chronos: the Use of Chronobiological Treatment in Depression treatment Not Available completed NCT01034995
A Trial Evaluating the Efficacy and Tolerability of SSR125543 in Outpatients With Major Depressive Disorder treatment 2 completed NCT00531895
An Open Trial of Duloxetine on Comorbid Major Depression and Chronic Headache treatment 4 completed NCT01792414
Transcranial Electrical Stimulation (TES) for the Treatment of Depression. No drug interventions treatment Not Available completed NCT01178255
Efficacy and Safety of Homeopathy for Moderate Depression (Acute Phase) No drug interventions treatment 3 terminated NCT05964023
pBFS Guided VS "5-cm Rule" rTMS Over DLPFC for MDD No drug interventions treatment Not Available recruiting NCT00466323
The Effectiveness of FMPO in Improving the Quality of Care for Persons With Severe Mental Illness. No drug interventions treatment Not Available completed NCT00220623
Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression No drug interventions treatment 3 unknown_status NCT02119923
Tackling Depression and Anxiety: A Working Memory Intervention No drug interventions treatment Not Available completed NCT03670823
Prediction of SSRI Treatment in Major Depression. No drug interventions Not Available Not Available unknown_status NCT02916238
Measurement-based Care for Depression in Resource-Poor Settings treatment 4 completed NCT00419003
Research Study for Major Depressive Disorder: Investigation of Glutamate Medications treatment 4 completed NCT03492203
Remote Cognitive Remediation for Depression No drug interventions treatment Not Available unknown_status NCT05669703
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder No drug interventions Not Available Not Available recruiting NCT01313403
Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder No drug interventions other Not Available withdrawn NCT01778790
Deep Brain Stimulation of the Superolateral Branch of the Medial Forebrain Bundle (slMFB) for the Treatment of Refractory Major Depression No drug interventions treatment 2 completed NCT01738464
Microbiomes of Pelvic Pain No drug interventions Not Available Not Available completed NCT01492621
Effect of Antidepressants on White Matter Structure basic_science 4 unknown_status NCT01391221
Inflammatory Markers and Cognitive Function in Major Depression basic_science 4 unknown_status NCT06384521
Lifestyle MIND- Feasibility of Wait-list Control No drug interventions treatment Not Available not_yet_recruiting NCT00460902
Evaluation of the Deep TMS H-Coil in the Treatment of Major Depression- Augmentation of Antidepressant Medication No drug interventions treatment 1 / 2 completed NCT05257902
Clinical Effectiveness of Choline Alphoscerate for Older Adults With Major Depression and Subjective Memory Complaints treatment Not Available not_yet_recruiting NCT00208702
Thyroid Medication and Antidepressants for Treating Major Depression treatment 4 completed NCT03973268
Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression No drug interventions basic_science 1 recruiting NCT06580145
Leucine in Midlife Depression No drug interventions treatment 2 not_yet_recruiting NCT01980147
Skills for Wellness No drug interventions prevention Not Available recruiting NCT03015285
CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT No drug interventions treatment Not Available completed NCT02122562
Ketamine Alcohol (in Treatment-Resistant Depression) treatment 2 recruiting NCT03005574
Comparing Thinking Skills for Work (TSW)Home Practice Program With Traditional TSW Program No drug interventions treatment Not Available completed NCT04480918
University of Iowa Interventional Psychiatry Service Patient Registry Not Available Not Available recruiting NCT04898725
Effects of Vitamin D Supplementation on Depression and Inflammatory Markers No drug interventions health_services_research Not Available completed NCT06500533
Combining rTMS and tDCS in Depression: an Exploratory Clinical Trial No drug interventions treatment Not Available recruiting NCT04575285
Using EEG to Predict Depression Treatment Response to rTMS in Patients With Major Depression No drug interventions Not Available Not Available withdrawn NCT03170362
PRIME Care (PRecision Medicine In MEntal Health Care) No drug interventions treatment Not Available completed NCT03913013
Technology Enhanced Family Treatment No drug interventions treatment 1 / 2 completed NCT05575960
Interpersonal Psychotherapy for Adolescents and Young Adults No drug interventions treatment Not Available recruiting NCT05097586
RCT of At-Home tDCS for Depression in Pregnancy No drug interventions treatment Not Available recruiting NCT02998580
Conventional Bilateral rTMS vs. Bilateral Theta Burst Stimulation for Late-Life Depression No drug interventions treatment Not Available completed NCT04352101
Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits treatment 4 completed NCT03000530
A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder treatment 2 completed NCT05551585
Transcranial Pulse Stimulation for Depression No drug interventions basic_science Not Available recruiting NCT05894902
Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults No drug interventions treatment 1 not_yet_recruiting NCT04388748
Stress Management and Resiliency Training for Depression vs Treatment as Usual in the Treatment of Major Depression No drug interventions supportive_care Not Available completed NCT00695552
The Effect of Exercise on Depressive Symptoms in Unmedicated Patients No drug interventions treatment Not Available terminated NCT04134871
Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI No drug interventions treatment Not Available completed NCT00178932
Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors No drug interventions diagnostic Not Available recruiting NCT01346306
Trial of Transcranial Direct Current Stimulation (tDCS) No drug interventions treatment Not Available completed NCT02648165
Secondary Prevention of Depression Through Group-based ACT-Therapy Preceded by an Experimental ABM-Procedure No drug interventions prevention Not Available completed NCT05497414
Neuroimaging Sleep and Mood in Depression No drug interventions basic_science Not Available recruiting NCT04489485
Online System for Identifying and Addressing Teen Depression in Primary Care No drug interventions Not Available Not Available recruiting NCT04235712
Implementation of Harmonized Depression Outcome Measures in a Health System No drug interventions Not Available Not Available completed NCT04093960
Escitalopram Plus PS128 vs. Escitalopram No drug interventions treatment 4 terminated NCT03927950
Investigation of Genetic Predictors of the Response to Selective Serotonin Re-uptake Inhibitors (SSRI) Treatment treatment 4 completed NCT03623724
iCare4Depression: Effectiveness of a Blended Cognitive-Behavioral Therapy in Routine Practice No drug interventions treatment Not Available unknown_status NCT03484754
Infiltrations of OnaBotulinum Toxin A in Resistant Depression: Comparison of Two Facial Injection Sites. No drug interventions treatment Not Available active_not_recruiting NCT03472638
Dorsomedial rTMS For Depression In Borderline Personality Disorder No drug interventions treatment Not Available unknown_status NCT03092687
Procedures for Sample Acquisition and Distribution for The Human Brain Collection Core No drug interventions Not Available Not Available terminated NCT03062150
Mineralocorticoid Receptor, NMDA Receptor and Cognitive Function in Depression basic_science Not Available completed NCT03060967
Assessment of Hedonic and Motivational States in Major Depression ( MOODDIS) No drug interventions screening Not Available unknown_status NCT03043833
Internet-Delivered Cognitive Behavior Therapy for Anxiety and Depression Amongst French Canadians No drug interventions treatment Not Available completed NCT03039387
Effects of tDCS on Cognitive Control and Emotion Regulation in Depressed Patients No drug interventions basic_science Not Available unknown_status NCT02988024
Pilot BA Study of New LY03005 vs Pristiq treatment 1 completed NCT02969876
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine basic_science 4 terminated NCT02931487
Restoring Emotion Regulation Networks in Depression Vulnerability No drug interventions prevention Not Available completed NCT02914769
Antidepressant Effects of Ayahuasca: a Randomized Placebo Controlled Trial in Treatment Resistant Depression No drug interventions treatment 1 / 2 completed NCT02894736
Home-Administered Trial of Direct Current Stimulation No drug interventions treatment Not Available completed NCT02891564
ESTIA: Computerized Intervention Targeting Cognitive Control Deficits in Depressed Adults No drug interventions treatment Not Available completed NCT02872454
Psychotherapeutic Text Messaging for Depression Pilot Study No drug interventions supportive_care Not Available completed NCT02855918
Blood Biomarkers in Suicidal Behaviour No drug interventions other Not Available completed NCT02845349
Vortioxetine for the Treatment of Major Depression and Co-morbidities After Traumatic Brain Injury (TBI) treatment 3 withdrawn NCT02653235
Impact of Immune Challenge on Triple Network Connectivity in Humans No drug interventions basic_science Not Available unknown_status NCT02633449
Psychotherapy Plus: Combining Cognitive Behavioral Therapy With tDCS No drug interventions treatment Not Available completed NCT02622633
Epidural Stimulation for Resistant Depression Treatment No drug interventions treatment 2 unknown_status NCT02520024
Assessing the Impact of Self-directed Care, Within a Medicaid-funded Environment,on Participation and Community Living No drug interventions Not Available Not Available completed NCT02520271
Ostrobothnia Depression Study (ODS). A Naturalistic Follow-up Study on Depression and Related Substance Use Disorders No drug interventions health_services_research Not Available completed NCT02507349
Person-Centered Versus Measurement-Based Care in Mental Health No drug interventions treatment Not Available completed NCT02484456
Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder No drug interventions treatment 2 completed NCT02476877
A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse No drug interventions Not Available Not Available completed NCT02441387
Predictors of the Outcome of Late Life Depression Not Available Not Available unknown_status NCT02439099
Retinoic Acid Homeostasis in Neuropsychiatric Diseases No drug interventions Not Available Not Available recruiting NCT02434393
Characterizing Cognitive Decline in Late Life Depression: The ADNI Depression Project No drug interventions Not Available Not Available active_not_recruiting NCT02379767
Effects of ECT on Monoamine Oxidase A in Depression Investigated With PET No drug interventions Not Available Not Available completed NCT02276469
Peer Support for Severe Mental Disorders No drug interventions treatment Not Available completed NCT02270073
The Process Outcome Mindfulness Effects in Trainees (PrOMET)-Study No drug interventions treatment Not Available completed NCT02238977
Bupropion for Depression in ESRD Patients on Hemodialysis treatment 4 terminated NCT02237937
Optimizing Antidepressant Treatment by Genotype-dependent Adjustment of Medication According to the ABCB1 Gene Not Available 4 unknown_status NCT02171923
Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression No drug interventions Not Available Not Available completed NCT02143024
A Family-based Primary Care Intervention to Enhance Older Men's Depression Care No drug interventions treatment Not Available completed NCT02119975
A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals No drug interventions treatment Not Available completed NCT02086201
Comparing Engage to PST for Late Life Depression No drug interventions treatment Not Available completed NCT02062840
The Brain on Whole Body Hyperthermia: A Neuroimaging Study No drug interventions treatment Not Available completed NCT01962753
Depression in the Elderly and Cerebral Amyloid Plaques: Characterization by [18F] AV-45 Affectives Symptoms and AmyloĂŻd Plaques (ASAP) diagnostic Not Available completed NCT01932931
Vitamin D, SSRIs and the Musculoskeletal System No drug interventions prevention Not Available completed NCT01926613
Thinking Skills for Work in Severe Mental Illness No drug interventions treatment Not Available completed NCT01893749
Primary Care Internet Based Depression Prevention for Adolescents (CATCH-IT) Also Known as Promoting AdolescenT Health No drug interventions prevention Not Available completed NCT01884025
Get Moving and Get Well - Pilot Study No drug interventions treatment Not Available completed NCT01870219
Effects of Sevoflurane and Ketamine on QT in Electroconvulsive Therapy treatment 4 completed NCT01851356
Brain Inflammation in Major Depressive Disorder Background No drug interventions Not Available Not Available completed NCT01830088
Family Based Treatment of Depressed Adolescents (AHUS) No drug interventions treatment Not Available terminated NCT01824433
Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression treatment 4 completed NCT01811147
Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI diagnostic 4 completed NCT01803711
Omega 3 FA Supplements as Augmentation in the Treatment of Depression treatment 2 / 3 terminated NCT01768052
Functional Brain Imaging Study of Response to Repetitive TMS (rTMS) Treatment of Major Depression No drug interventions Not Available Not Available unknown_status NCT01754493
Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major Depression treatment 4 completed NCT01749124
My Coach Connect: An Automated Telephone-based Reporting System for Patients With Mental Illness No drug interventions health_services_research Not Available unknown_status NCT01750359
Efficacy and Safety Curcumin in Depression treatment 4 completed NCT01731899
Agomelatine in Depressed Patients With Fibromyalgia Not Available Not Available completed NCT01683539
Understanding How Cognitive Remediation Works No drug interventions treatment Not Available completed NCT01667809
CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care No drug interventions treatment 3 completed NCT01663844
New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression No drug interventions treatment Not Available completed NCT01652391
Modulation of Cognitive Control by Transcranial Direct Current Stimulation No drug interventions basic_science Not Available completed NCT01594528
Behavior During Experimentally Induced Pain No drug interventions prevention Not Available completed NCT01571011
Chicago Urban Resiliency Building (CURB) No drug interventions prevention Not Available completed NCT01566318
Depression Agency-Based Collaboration No drug interventions prevention Not Available completed NCT01561105
Improving Depression Care for Elders: Coordinating Center No drug interventions treatment Not Available completed NCT01559324
Electroconvulsive Therapy (ECT) for Elderly Patients With Major Depression No drug interventions treatment 4 completed NCT01556971
Efficacy Study of Botox for Depression treatment 4 unknown_status NCT01542229
PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness) No drug interventions health_services_research Not Available completed NCT01529905
Longitudinal Study of People Presenting for First Treatment of a Mood Disorder No drug interventions Not Available Not Available unknown_status NCT01399671
Study of the Effectiveness of Vestibular Stimulation as a Coadjuvant Treatment in Major Depression No drug interventions treatment Not Available completed NCT01368432
Lexapro for the Treatment of Traumatic Brain Injury (TBI) Depression & Other Psychiatric Conditions treatment 2 completed NCT01358487
Healthy Mood Internet Intervention Research Project No drug interventions prevention Not Available completed NCT01309581
Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression treatment Not Available terminated NCT01263275
Trial of Transcranial Direct Current Stimulation (tDCS) for Depression No drug interventions treatment 2 completed NCT01244711
Open-Label Pilot Study to Examine the Value of Substituting Quetiapine for Benzodiazepines treatment 4 terminated NCT01244724
Lexapro for Major Depression in Patients With Epilepsy treatment 4 terminated NCT01230047
Mindfulness and Lifestyle Interventions for Depression and Anxiety: A Pilot Study No drug interventions treatment Not Available unknown_status NCT01208428
Cognitive Behavioral Treatments for Depression in Chronic Illness No drug interventions treatment Not Available completed NCT01191580
Interpersonal Therapy for Depression in Breast Cancer No drug interventions treatment 4 completed NCT01178424
My Depression Wellness Toolkit Study No drug interventions treatment Not Available completed NCT01150604
Depression Management Project No drug interventions treatment Not Available completed NCT01147913
Computerized Information-Processing Bias Retraining in Depressed Adolescents No drug interventions treatment 2 completed NCT01135758
Study of Depression-Ketamine-Brain Function treatment 2 terminated NCT01114334
Motivational Interviews for Depression in Primary Care No drug interventions health_services_research Not Available completed NCT01095263
Effects of Deep Brain Stimulation in Treatment Resistant Major Depression No drug interventions treatment 1 completed NCT01062880
Neuropattern - Assessment of a Translational Diagnostic Tool for Depression, Adjustment- and Somatoform-disorders No drug interventions diagnostic Not Available unknown_status NCT01027559
fMRI Study of Treatment Changes in Major Depression other Not Available completed NCT01021709
Trial of Transcranial Direct Current Stimulation (tDCS) Using Alternative Electrode Montages No drug interventions treatment 2 completed NCT00982345
Brain Imaging of Quetiapine Response in Anxious Depression treatment 4 completed NCT00977353
N-methylglycine (Sarcosine) Treatment for Depression treatment 2 completed NCT00965497
Escitalopram (Lexapro) for Depression MS or ALS treatment 3 completed NCT00961454
Photobiomodulation to Alter Cerebral Blood Flow and to Affect the Emotional Status of Patients With Major Depression No drug interventions treatment 1 completed NCT00953108
Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed Patients treatment 3 completed NCT00825799
Serum Markers as a Bioassay for Unipolar Depression No drug interventions Not Available Not Available completed NCT00817154
Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI) No drug interventions health_services_research 1 completed NCT00806143
Bilateral Versus Monolateral Repetitive Transcranial Stimulation in Depression No drug interventions treatment 4 completed NCT00797901
Depression Treatment in General Medical Settings No drug interventions treatment Not Available completed NCT00792168
Physiologic Monitoring of Antidepressant Treatment Response treatment 4 completed NCT00781703
Evaluation of a Natural Experiment to Improve Statewide Depression Care in Minnesota (MN) No drug interventions health_services_research Not Available completed NCT00770783
Magnetic Seizure Therapy (MST) for Treatment Resistant Major Depression No drug interventions treatment 3 completed NCT00765752
Cortical GABA Concentrations in Insomnia No drug interventions Not Available Not Available completed NCT00711737
Study of the Changes in Metabolic Parameters in Patients Treated With Escitalopram for Six Months No drug interventions Not Available Not Available completed NCT00704860
Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism No drug interventions treatment 4 completed NCT00700609
Family Based Treatment of Depressed Adolescents No drug interventions treatment 2 terminated NCT00699218
A Pilot Study on Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Bipolar Depression No drug interventions device_feasibility Not Available completed NCT00693680
Zinc Supplementation of Imipramine Therapy No drug interventions treatment Not Available completed NCT00675896
A Study of Quetiapine Fumarate Sustained Release in Major Depression With Comorbid Fibromyalgia Syndrome treatment 4 completed NCT00660062
Relapse Prevention With Escitalopram or Nortriptyline Following Electro-Convulsive Treatment (DUAG-7) treatment 4 terminated NCT00650897
Efficacy Study of Escitalopram for Depression in Patients With Diabetes treatment 4 unknown_status NCT00619411
Interpersonal Psychotherapy for Depressed Adolescents and Parents No drug interventions treatment 1 completed NCT00616759
The Effect on Cognition of Terminating ECT Induced Seizures With Propofol treatment Not Available completed NCT00605358
Increasing Use of Mental Health Services No drug interventions supportive_care Not Available completed NCT00595699
Escitalopram Treatment of Major Depression in Patients With Temporal Lobe Epilepsy treatment 4 completed NCT00576875
Duke Conte Center for the Neuroscience of Depression in Late Life No drug interventions Not Available Not Available completed NCT00577070
Evaluation of the H-Coil Transcranial Magnetic Stimulation(TMS) Device- Augmentation for Drug Resistant Depression No drug interventions treatment 2 completed NCT00570583
Neurocognitive Outcomes of Depression in the Elderly No drug interventions Not Available Not Available completed NCT00565110
Treating Depression Among Low-Income Patients With Cancer No drug interventions treatment Not Available completed NCT00523302
A Pilot Study of TMS Effects on Pain and Depression in Patients With Fibromyalgia No drug interventions treatment Not Available completed NCT00510822
Cimicoxib for the Treatment of Major Depression (SECIM) treatment 2 completed NCT00472576
Antidepressant Effects of NR2B in Major Depression treatment 1 completed NCT00461279
Attachment Security as Mediator and Moderator of Outcome in Major Depression No drug interventions treatment Not Available completed NCT00445237
Evaluation of Deep Transcranial Magnetic Stimulation (TMS) H-Coil in the Treatment of Major Depression No drug interventions treatment 1 completed NCT00437385
Evaluation of Three Continuation Therapies After ECT Concerning Efficacy and Cognition in Severly Depressed Patients treatment 1 completed NCT00427128
Prozac Treatment of Major Depression: Discontinuation Study treatment 4 completed NCT00357045
Antidepressant Prophylaxis for Interferon-Induced Depression: Efficacy of Paroxetine Not Available 4 completed NCT00345098
A Study of SR58611A in the Prevention of Depression Relapse in Patients With Major Depressive Disorder treatment 3 completed NCT00343070
Functional Neuroimaging in Depression treatment 2 completed NCT00325000
Interpersonal Psychotherapy for Severely Depressed Inpatients treatment Not Available terminated NCT00322777
Spirituality Teaching Program for Depressed Adults No drug interventions treatment Not Available completed NCT00296777
Treatment of Depression Following Multiple Brain Tests treatment 4 completed NCT00295347
Mineralocorticoid Receptor in the Treatment of Severe Depression treatment Not Available completed NCT00289484
A Study of Omega-3 as an Augmentor of Antidepressant Treatment for Major Depression treatment 2 unknown_status NCT00286546
Testosterone and Major Depression No drug interventions Not Available Not Available completed NCT00285766
Safety, Tolerability and Efficacy of the Transdermal System in Elderly Subjects With Major Depression treatment 3 completed NCT00269334
Clinical Pharmacogenomics of Antidepressant Response treatment 4 unknown_status NCT00265291
Antidepressant Treatment of Mexican-Americans: UCLA Pharmacogenetics and Pharmacogenomics Research Group treatment 2 completed NCT00238758
A Study of Omega-3 as a Treatment for Major Depression treatment 2 unknown_status NCT00222820
Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study treatment 4 completed NCT00209807
Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder treatment 4 unknown_status NCT00208715
Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue. treatment 4 completed NCT00203723
Use of Risperidone in ECT for Treatment Resistant Depression treatment 4 terminated NCT00174577
Risperidone Augmentation Therapy in Patients Who Have Failed or Only Partially Responded to a Trial of Antidepressant treatment 3 unknown_status NCT00169052
Health Care Management and Rehabilitation Skills Training for Treating Serious Mental Illness in Older People No drug interventions treatment Not Available completed NCT00168493
The Neurobiology of Depressive Illness treatment Not Available unknown_status NCT00167310
Decreasing Risk of Coronary Artery Disease in Schizophrenia by Omega-3 Fatty Acid Supplementation treatment 2 completed NCT00158990
Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression. treatment 3 completed NCT00149071
Transcranial Magnetic Stimulation (rTMS) Accelerates the Response to Escitalopram in Major Depression No drug interventions treatment Not Available completed NCT00119028
Expanding and Testing VA Collaborative Care Models for Depression No drug interventions Not Available Not Available withdrawn NCT00105885
Telephone Care as a Substitute for Routine Psychiatric Medication No drug interventions treatment Not Available completed NCT00088699
Rapid Antidepressant Effects of Ketamine in Major Depression other 1 / 2 completed NCT00086307
Lexapro and Pramipexole and to Treat Major Depression treatment 2 completed NCT00078715
Rapid Antidepressant Effects of Yohimbine in Major Depression other 2 completed NCT00005013
Treatment of Major Depression With St. John's Wort (Hypericum) treatment Not Available completed NCT01179516
Safety and Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder treatment 3 completed NCT06398496
The Effects of Exercise on Gut Bacteria, Mood and Cognition in Depression No drug interventions basic_science Not Available recruiting NCT01241435
A Study of LY2216684 in Participants With Impaired Hepatic Function treatment 1 completed NCT06280235
A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine No drug interventions treatment 2 recruiting NCT00229463
Study of Genetic Differences in People With Depression No drug interventions Not Available Not Available completed NCT06431386
Behavioural Activation Therapy and Esketamine for Resistant Depression treatment Not Available recruiting NCT05008939
Sevoflurane for Treatment-Resistant Depression treatment Not Available unknown_status NCT00150839
Hippocampal Volume in Young Patients With Major Depression Before and After Combined Antidepressive Therapy treatment 4 completed NCT04486222
Accelerated Bilateral rTMS on Geriatric Depression No drug interventions treatment Not Available terminated NCT02741622
Brain Derived Neurotropic Factor Response to Aerobic Exercise Intensity in Depressive Patients. No drug interventions treatment Not Available completed NCT03489122
A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans No drug interventions treatment Not Available terminated NCT03932825
Nitrous Oxide for Major Depressive Disorder treatment 2 completed NCT03108625
Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age treatment 3 completed NCT02076425
A Randomized Controlled Trial of PCIT-ED for Preschool Depression No drug interventions treatment Not Available completed NCT00763230
A Study of Transcranial Direct Current Stimulation (tDCS) to Treat Depression No drug interventions treatment 2 / 3 completed NCT01718730
Cortical Excitability and Inhibition in MDD No drug interventions Not Available Not Available completed NCT04790630
Cognitive Fitness for Depression in Older Adults No drug interventions treatment Not Available recruiting NCT04476030
A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder treatment 3 completed NCT04423757
A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression No drug interventions treatment 2 terminated NCT04761757
Antidepressant Decision Aid for Major Depressive Disorder Patients No drug interventions health_services_research Not Available completed NCT00655226
Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients No drug interventions treatment Not Available terminated NCT00057226
An 8 Week Study Of Adults Diagnosed With Major Depressive Disorder treatment 2 completed NCT00762866
Psychiatric Genotype/Phenotype Project Repository No drug interventions Not Available Not Available enrolling_by_invitation NCT01360866
Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) treatment 3 completed NCT02342366
Characterization of the Prosocial and Prosexual Effects of GHB other Not Available completed NCT02997865
Stepped Care for Depression in Heart Failure No drug interventions treatment Not Available completed NCT03866174
A Study of Psilocybin for Major Depressive Disorder (MDD) treatment 2 completed NCT00497874
An Expert System to Reduce Depression in Primary Care No drug interventions treatment 2 completed NCT00696774
Switching to Duloxetine in Patients With Depression treatment 4 completed NCT00046020
Study Evaluating Venlafaxine ER in Recurrent Depression treatment 4 completed NCT00644982
A Comparison of Sertraline Versus Venlafaxine XR in the Treatment of Major Depression treatment 4 completed NCT01373931
A Study of LY2216684 in Healthy Females treatment 1 completed NCT03414931
NMDA Modulation in Major Depressive Disorder in Late- Life treatment 2 completed NCT01477931
Interventional Study of Wellbutrin XL in Major Depressive Disorder With Atypical Features treatment 4 completed NCT05267873
Combining Data Sources to Identify Effect Moderation for Personalized Mental Health Not Available Not Available active_not_recruiting NCT05680727
Individualized Functional Connectivity Targeting in aiTBS for Depression No drug interventions treatment 2 recruiting NCT03586427
AGN-241751 in the Treatment of Major Depressive Disorder treatment 2 completed NCT03715127
Clinical, Neurocognitive, and Emotional Effects of Psilocybin in Depressed Patients - Proof of Concept treatment 2 completed NCT00229476
Study of Medication and Placebo Response in Major Depression treatment 4 completed NCT00285376
Effectiveness Study of Vilazodone to Treat Depression and to Discover Genetic Markers Associated With Response treatment 3 completed NCT02370576
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology No drug interventions Not Available Not Available unknown_status NCT02039960
PRJ2215: Assessment of Buproprion Misuse/Abuse 2004-2011 Not Available Not Available completed NCT00316160
Sexual Functioning Study With Antidepressants treatment 4 completed NCT00976560
Clinical Study to Test a New Drug to Treat Major Depression treatment 2 completed NCT06005194
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI No drug interventions treatment Not Available recruiting NCT00844194
Duloxetine in Patients With Diabetic in Peripheral Neuropathic Pain With or Without Co-morbid Major Depressive Disorder treatment 4 completed NCT00143091
Multicentre Trial to Evaluate the Safety and Efficacy of CP-316,311 in Major Depressive Disorder treatment 2 terminated NCT00824291
Study Evaluating Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder treatment 3 completed NCT02529462
Trial to Evaluate Efficacy of Pharmacogenetic Information Obtained With NEUROPHARMAGEN in Treatment of MDD Patients No drug interventions treatment 3 completed NCT00569062
A Study of GW856553X For the Treatment of Depression treatment 2 terminated NCT00220480
A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression treatment Not Available unknown_status NCT04937829
A Study to Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication No drug interventions treatment 1 completed NCT05121129
Treatment of Major Depression by rTMS on Dorsolateral Prefrontal Cortex: Study of Underlying Mechanisms No drug interventions treatment Not Available recruiting NCT00105989
Duloxetine Versus Placebo in the Prevention of Recurrence of Major Depressive Disorder treatment 3 completed NCT02473289
An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder treatment 2 completed NCT03872492
Major Depressive Disorder: Early Prediction of Non-response to Antidepressant Therapy Via a Mobile Digital Scale No drug interventions other Not Available terminated NCT03014544
Study to Evaluate the Performance Validity and Test-Retest Reliability of a Computer-Administered Cognitive Test Battery in Participants With Major Depressive Disorder (MDD) No drug interventions Not Available Not Available completed NCT05210140
Personalized Escitalopram Dosing in Patients With Depression Not Available Not Available unknown_status NCT00406640
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) vs. Escitalopram in Postmenopausal Women treatment 3 completed NCT02845440
Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness No drug interventions treatment Not Available completed NCT04526067
In-person vs. Remote Wellness Support No drug interventions treatment Not Available completed NCT02219867
Ketamine Infusions for Major Depression Disorder treatment Not Available unknown_status NCT02919501
Study of the Efficacy and Safety of Initial Administration of 17 mg Vortioxetine Intravenously With 10 mg/Day Vortioxetine Orally in Patients With Major Depressive Disorder treatment 2 completed NCT02902601
A Study to Investigate the Safety, Tolerability, and Pharmacodynamics of JNJ-54175446 in Participants With Major Depressive Disorder treatment 1 completed NCT02407704
A Multi-level Life-span Characterization of Adult-depression and Effects of Medication and Exercise treatment 4 completed NCT05630469
Prediction of Antidepressant Effects of Electroconvulsive Therapy No drug interventions Not Available Not Available recruiting NCT04829669
A Study of Participants With Moderate or Severe Major Depressive Disorder (MDD) Requiring Urgent Symptom Control in a Psychiatric Emergency No drug interventions Not Available Not Available withdrawn NCT00304746
AndroGel in Men With Major Depression and Incomplete Response to Antidepressant Treatment treatment 4 completed NCT02709746
Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD) treatment 3 completed NCT01625546
Whole Body Hyperthermia and Major Depression (MDD) No drug interventions treatment Not Available completed NCT04159012
NESBID: Neuro-Stimulation of the Brain in Depression No drug interventions treatment Not Available active_not_recruiting NCT00613912
Advanced MRI in Major Depression No drug interventions Not Available Not Available completed NCT04148612
A Study to Evaluate the Benefit of Opti-Me Application to Different Treatments of MDD No drug interventions supportive_care Not Available unknown_status NCT04513912
A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy treatment 3 completed NCT00044681
A Study of the Effectiveness and Safety of Risperidone to Augment SSRI Therapy in Patients With Treatment-resistant Depression treatment 3 completed NCT04893395
Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans No drug interventions screening Not Available withdrawn NCT00576095
Clinical and Biological Characteristics of Psychotic Depression No drug interventions Not Available Not Available completed NCT05109195
A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant No drug interventions Not Available Not Available terminated NCT05450614
Smartphone App Based CBT Versus Online Group CBT: Randomized, Non-inferiority Clinical Trial No drug interventions treatment Not Available unknown_status NCT05076214
Aerobic Versus Leisure Group for Adolescents With Depression No drug interventions treatment Not Available recruiting NCT04870255
Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS No drug interventions treatment Not Available recruiting NCT05716555
Deep Brain Stimulation for Treatment Resistant Depression No drug interventions treatment Not Available recruiting NCT02709655
Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD) treatment 3 completed NCT02232555
Study to Evaluate the Efficacy of Duloxetine in Outpatients With Major Depressive Disorder and Pain treatment 3 completed NCT04260750
ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content No drug interventions treatment Not Available completed NCT00413023
Study Of The Effects Of A New Antidepressant Therapy In Patients With Major Depressive Disorder (MDD) treatment 2 completed NCT05686408
Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD) treatment 2 completed NCT03207438
Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression treatment 4 completed NCT05933538
Effectiveness of Cariprazine Monotherapy for Treatment of Major Depressive Disorder treatment 4 not_yet_recruiting NCT03971903
Attention Bias Modification Treatment for Young Adults With Major Depressive Disorder No drug interventions treatment Not Available completed NCT00186264
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response? treatment Not Available completed NCT02943564
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02) treatment 3 completed NCT00795821
A Study in Adult Patients With Major Depressive Disorder treatment 2 / 3 completed NCT01033084
Efficacy Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder treatment 2 / 3 completed NCT05306184
Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA No drug interventions Not Available Not Available recruiting NCT01568684
Brain Imaging, Genetics and Treatment for Major Depression No drug interventions treatment 1 withdrawn NCT05455684
A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy treatment 3 recruiting NCT02919579
A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder treatment 1 completed NCT00445679
Paroxetine-referenced Study Evaluating Three Doses of DVS SR in Outpatients With MDD treatment 3 completed NCT06511908
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression No drug interventions treatment 2 not_yet_recruiting NCT06580041
Precision Care for Major Depressive Disorder treatment 4 not_yet_recruiting NCT06559306
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms treatment 3 recruiting NCT05194332
Transcranial Low Intensity Focused Ultrasound Neuromodulation as a Probe to Study Human Emotion and Cognitive Function No drug interventions basic_science Not Available not_yet_recruiting NCT05550532
A Study of Aticaprant 10 Milligrams (mg) as Adjunctive Therapy in Adult Participants With MDD With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy treatment 3 recruiting NCT06308653
Psilocybin for Major Depressive Disorder (MDD) treatment 3 recruiting NCT04829318
A Long-Term Extension Study for Participants With Treatment-resistant Major Depressive Disorder Who Are Continuing Esketamine Nasal Spray Treatment treatment 4 completed NCT05518149
A Study of Aticaprant in Adult and Elderly Participants With Major Depressive Disorder (MDD) treatment 3 recruiting NCT06558344
A Study to Test Different Doses of BI 1569912 in People With Depression No drug interventions treatment 2 not_yet_recruiting NCT05841030
A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI) No drug interventions Not Available Not Available recruiting NCT06514742
A Study of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant treatment 3 recruiting NCT06546917
bWell-D Pilot Randomized Controlled Trial No drug interventions treatment Not Available not_yet_recruiting NCT06470035
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD) No drug interventions treatment Not Available not_yet_recruiting NCT06528938
Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents Depression No drug interventions treatment Not Available not_yet_recruiting NCT05553353
Dosing rTMS for Depression Post-SCI No drug interventions treatment Not Available not_yet_recruiting NCT04301271
Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression treatment 2 active_not_recruiting NCT04533529
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant treatment 3 completed NCT05708222
Sleep Signal Analysis for Current Major Depressive Episode (SAMDE) No drug interventions Not Available Not Available completed NCT05909267
Dopamine Modulation of Motivation and Motor Function in Major Depression & Inflammation basic_science Not Available recruiting NCT06398561
Peer-led Intervention for Individuals With Major Depression. No drug interventions treatment Not Available recruiting NCT06152705
Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating Depression No drug interventions treatment Not Available recruiting NCT04695145
Aerobic Group Exercise for Adolescents With Depression No drug interventions treatment Not Available completed NCT04951609
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy treatment 1 terminated NCT05232032
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation basic_science 2 not_yet_recruiting NCT06417619
The Effect of Mindfulness-Based Psychoeducation No drug interventions treatment Not Available recruiting NCT03367533
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response basic_science 1 completed NCT06389175
Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression No drug interventions basic_science Not Available enrolling_by_invitation NCT04532749
A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy treatment 3 terminated NCT03185819
Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide treatment 2 completed NCT05988333
Psychoeducational Intervention for Families With a Member Affected by Major Depression No drug interventions supportive_care Not Available recruiting NCT00617162
Deep Brain Stimulation for Major Depressive Disorder No drug interventions treatment Not Available terminated NCT05915013
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response basic_science 1 recruiting NCT04521478
A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression treatment 2 completed NCT04772664
Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve? No drug interventions basic_science Not Available completed NCT06311136
Effectiveness of an Ecological Momentary Emotion Regulation Intervention No drug interventions treatment Not Available recruiting NCT06320028
Altering Default Mode Network Activity With Transcranial Focused Ultrasound to Reduce Depressive Symptoms No drug interventions treatment 1 / 2 active_not_recruiting NCT06303076
Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized Trial treatment 4 not_yet_recruiting NCT06012916
Brain Network Dynamics of Depression During Esketamine Treatment Not Available Not Available recruiting NCT06254144
Neuroimaging Study for Decoding Emotional States and Identifying Neural Circuits to Disengage From Negative Thinking No drug interventions Not Available Not Available enrolling_by_invitation NCT05146427
Pilot Study: Investigating Mood Changes After Slow-wave Enhancement No drug interventions basic_science Not Available not_yet_recruiting NCT01038765
Mindfulness Based Cognitive Therapy for Recurrent Depression No drug interventions treatment Not Available completed NCT03288675
Stepped Care aiTBS 2 Depression Study (Ghent) treatment Not Available completed NCT06035159
The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health Problems No drug interventions other Not Available recruiting NCT06219681
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression No drug interventions basic_science Not Available recruiting NCT05554627
VA Aripiprazole vs Esketamine for Treatment Resistant Depression treatment 4 withdrawn NCT03207503
Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan No drug interventions Not Available Not Available completed NCT04442490
A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD) treatment 3 completed NCT05491538
Acceptability and Feasibility of Work-Oriented Social-Cognitive Skills Training for Veterans With Serious Mental Illness No drug interventions treatment Not Available recruiting NCT06136546
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab other 2 not_yet_recruiting NCT04581902
Biomarkers of Depression and Treatment Response No drug interventions treatment Not Available recruiting NCT03051256
Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD treatment 2 completed NCT05100004
Rapid Acting TMS for Suicide Ideation in Depression No drug interventions treatment Not Available recruiting NCT06110585
Transcranial Magnetic Stimulation in Patients With Depression and Non-suicidal Self-injury No drug interventions treatment Not Available recruiting NCT02229825
Study to Assess Clinical Response of Duloxetine in Patients Hospitalized for Severe Depression treatment 4 completed NCT04338321
A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder treatment 3 completed NCT04669665
A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide treatment 2 completed NCT05415397
Treating Immuno-metabolic Depression With Anti-inflammatory Drugs treatment 3 recruiting NCT05544877
An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study No drug interventions supportive_care Not Available completed NCT05041647
Cannabinoids as a Treatment for Insomnia in Major Depression No drug interventions treatment 2 recruiting NCT03674671
Ketamine Versus Electroconvulsive Therapy in Depression treatment 3 suspended NCT03679962
Triple Chronotherapy in Adolescents No drug interventions treatment Not Available completed NCT03227224
A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy treatment 2 completed NCT05211466
Digital Care Chains in Health Care - a Study of Care Consumption, Care Quality, Work Environment and Well-being No drug interventions Not Available Not Available active_not_recruiting NCT03559192
A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression No drug interventions treatment 2 completed NCT04770454
Evaluate the Quality of Life and Treatment of Anxiety Symptoms of Buspirone in Patients With Depression Disorders(BASIS) No drug interventions Not Available Not Available completed NCT05901571
Acupuncture and Escitalopram for Treating Major Depression Clinical Study No drug interventions treatment Not Available not_yet_recruiting NCT05870501
Synaptic Imaging and Network Activity in Treatment Resistant Depression basic_science Not Available recruiting NCT03374475
A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Participants With Major Depressive Disorder treatment 1 completed NCT03321526
A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy treatment 2 completed NCT04451187
A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder other 1 completed NCT05701267
Neuro MRI Biomarkers for Treatment Navigation in Depression No drug interventions Not Available Not Available recruiting NCT04994470
Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder No drug interventions treatment Not Available completed NCT03436823
Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder? No drug interventions treatment Not Available completed NCT02871297
Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of Age treatment 3 terminated NCT05616559
Precision Medicine in the Depression Treatment No drug interventions Not Available Not Available recruiting NCT05488418
Clinical Study of Biomarkers of Stress Resilience: Role of ELK1 and GPR56 No drug interventions diagnostic Not Available not_yet_recruiting NCT05423405
The Efficacy of Acupressure Therapy on Patient With Depression No drug interventions supportive_care Not Available not_yet_recruiting NCT05280015
Microbiotherapy in Characterized Depressive Disorder No drug interventions treatment 2 recruiting NCT05212636
Using Repetitive Transcranial Magnetic Stimulation to Study the Role of Frontostriatal Circuit in Major Depressive Disorder No drug interventions treatment Not Available completed NCT05210153
Personalized Sertraline Dosing in Patients With Depression Not Available Not Available recruiting NCT05111665
Decentering and Relapse/Recurrence in MBCT for Depression in Adults No drug interventions treatment Not Available completed NCT05047159
The Role of Neuromodulation Technique In Depression Disorder No drug interventions treatment Not Available not_yet_recruiting NCT04984512
The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder No drug interventions treatment 2 / 3 not_yet_recruiting NCT04963907
Alpha-Stim AID and Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT04701866
Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression No drug interventions treatment Not Available completed NCT04661475
Dexmedetomidine Adjuvant Treatment for Depressed Patients Undergoing ECT treatment 4 not_yet_recruiting NCT04498897
Vortioxetine for Treatment of Depressive Mood and Alcohol Use treatment 2 unknown_status NCT04469322
Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory Depression No drug interventions treatment Not Available completed NCT04463108
A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy No drug interventions Not Available Not Available completed NCT04272476
The Activation on Prefrontal Cortex With Acupuncture and Moxibustion for Major Depressive Disorder: A Study of Functional Near Infrared Spectroscopy treatment 2 completed NCT04179006
Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients No drug interventions treatment Not Available recruiting NCT04171193
Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent treatment 2 unknown_status NCT04116606
Antidepressant Trial With P2X7 Antagonist JNJ-54175446 treatment 2 active_not_recruiting NCT04099771
Ketamine for Mood Disorders With Suicidal Ideation treatment 0 unknown_status NCT04081519
Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive Disorder No drug interventions treatment Not Available completed NCT04057378
Optimal Electrical Stimulus During Electroconvulsive Therapy No drug interventions treatment 4 recruiting NCT04021433
Ketamine for Treatment Resistant MDD treatment Not Available unknown_status NCT04015206
Effectiveness of IPT-G in Major Depression No drug interventions treatment Not Available terminated NCT04013464
Effects of Escitalopram on the Sleep EEG Power in Patients With Major Depressive Disorder treatment Not Available completed NCT03944213
Resting-state Functional Connectivity Throughout a Course of iTBS in Major Depression No drug interventions Not Available Not Available recruiting NCT03899168
Confirmation Bias Towards Treatments of Depressive Disorders in Social Tagging No drug interventions health_services_research Not Available completed NCT03877393
The Effect of Probiotic Supplementation on the Mental Status, Inflammation, and Intestinal Barrier in Major Depressive Disorder Patients Using Gluten-free or Gluten-containing Diet treatment Not Available unknown_status NCT03855865
Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD) treatment 3 withdrawn NCT03854578
A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions treatment 1 completed NCT03832283
Patient Outcomes Reporting for Timely Assessments of Life With Depression: PORTAL-Depression No drug interventions health_services_research Not Available completed NCT03795051
Coil Positioning in Navigated Transcranial Magnetic Stimulation Feasibility in Depression Patients Trial No drug interventions treatment Not Available completed NCT03758495
Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression No drug interventions Not Available Not Available withdrawn NCT03721588
Clinical and Suicidal Features of Urban, Turkish Middle Age Depressive Patients With Comorbid ADHD No drug interventions Not Available Not Available completed NCT03675776
Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD) treatment 3 terminated NCT03668600
Study of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD) treatment 3 terminated NCT03614156
Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD) treatment 3 terminated NCT03605524
Olfactory Training and Emotional State No drug interventions other Not Available recruiting NCT03595020
Probing Prefrontal Cortex Hemodynamic Alterations for Major Depression Disorder No drug interventions Not Available Not Available unknown_status NCT03560518
Study of Rapastinel as Monotherapy in Patients With MDD treatment 3 terminated NCT03548675
Pharmacogenetics Informed Tricyclic Antidepressant Dosing (PITA) No drug interventions treatment 4 completed NCT03429075
Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms treatment 2 unknown_status NCT03405493
Sleep, Wake and Light Therapy for Depression No drug interventions treatment Not Available completed NCT03352453
A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive Disorder treatment 2 terminated NCT03288714
Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder No drug interventions treatment Not Available completed NCT03287037
The Effects of tDCS on Depressive Symptoms,Neurocognitive Function and HRV in Unipolar Depression and Bipolar Depression No drug interventions treatment Not Available completed NCT03283670
Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing Strategies treatment 2 completed NCT03165513
Dialogue to Empower Traditional and Faith Healers to Deliver mhGAP-IG Adapted Psychosocial Interventions in Kenya No drug interventions treatment Not Available completed NCT03155503
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-911 in Healthy Subjects No drug interventions treatment 1 completed NCT03121937
Feasibility of a Technology-Based Treatment Support System No drug interventions treatment Not Available terminated NCT03097133
54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide treatment 3 completed NCT03040388
Exploring Effects of Electroconvulsive Therapy on the Human Brain in Depression - The Danish ECT/MRI Study No drug interventions Not Available Not Available completed NCT03039192
54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide treatment 3 completed NCT03027362
Cognitive Therapy to Sustain the Antidepressant Effects of Intravenous Ketamine in Treatment-resistant Depression No drug interventions treatment Not Available completed NCT03016572
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide No drug interventions treatment Not Available completed NCT03002077
Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT03001440
A 7-year Assessment on Subject Understanding of ZYBAN/ WELLBUTRIN Associated Risks No drug interventions Not Available Not Available completed NCT02994433
NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits treatment 1 terminated NCT02983318
Molecular Imaging of Brain Inflammation in Depressive Disorders No drug interventions Not Available Not Available completed NCT02951988
A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive Disorder treatment 3 completed NCT02945735
Gaze Contingent Feedback in Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT02943577
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03) treatment 3 completed NCT02938559
Can the Memory Support Intervention Improve Depression Outcome Following Cognitive Therapy? No drug interventions treatment Not Available completed NCT02932943
A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01) treatment 3 completed NCT02752178
Peripheral Immunomarker Validation in Treatment-resistant Depression No drug interventions Not Available Not Available completed NCT02739932
Adolescent Mental Health: Canadian Psychiatric Risk and Outcome Study No drug interventions Not Available Not Available completed NCT02740296
Depression and Immune Function in Multiple Sclerosis (MS) No drug interventions Not Available Not Available completed NCT02737540
Neuropsychological Factors Associated With Vulnerability to Suicidal Behavior in Depressed Elderly Patients No drug interventions Not Available Not Available terminated NCT02698553
A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Extended-release Bupropion Hydrochloride Tablets in Chinese Healthy Volunteers treatment 1 completed NCT02667041
NeuroQore rTMS (Monophasic vs. Biphasic) for Major Depressive Disorder: A Randomized Controlled Pilot Trial No drug interventions treatment Not Available completed NCT02664467
Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project No drug interventions treatment Not Available completed NCT02659085
Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder treatment 2 / 3 completed NCT02546024
Predictors of Treatment Response in Late-onset Major Depressive Disorder No drug interventions Not Available Not Available suspended NCT02489305
Study to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD) No drug interventions Not Available Not Available completed NCT02466477
Pharmacogenomic Decision Support With GeneSight Psychotropic to Guide the Treatment of Major Depressive Disorder No drug interventions treatment 4 completed NCT02452892
Low Field Magnetic Stimulation (LFMS) in Subjects With Treatment-Resistant Depression (TRD) No drug interventions treatment Not Available completed NCT02410616
E-Compared-CH: Comparative Effectiveness Research on Internet-based Depression Treatment - Swiss Trial No drug interventions treatment Not Available completed NCT02340351
Auricular Acupuncture vs. Progressive Muscle Relaxation in Patients With Anxiety Disorders or Major Depressive Disorder. No drug interventions treatment Not Available completed NCT02314767
A Finnish Community Randomized Psychotherapy Effectiveness Study for Major Depression No drug interventions treatment Not Available completed NCT02288325
A Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive Disorder treatment 4 completed NCT02196506
Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress treatment 3 completed NCT02191397
Study to Evaluate the Efficacy, Safety and Tolerability of Bupropion Hydrochloride Extended-release Tablet, and Escitalopram Oxalate Capsule in Subjects With Major Depressive Disorder treatment 3 completed NCT02116361
OnabotulinumtoxinA as Treatment for Major Depressive Disorder in Adult Females treatment 2 completed NCT02067299
A Study to Investigate the Effect of JNJ-42847922 on Polysomnography Measures in Patients With Major Depressive Disorder With Insomnia Who Are Stably Treated With Antidepressants treatment 1 completed NCT02023567
Objective Diagnostic Markers and Personalized Intervention in MDD Patients basic_science Not Available unknown_status NCT01909232
A Clinical Trial for the Treatment of Depression With Repetitive Transcranial Magnetic Stimulation (rTMS) No drug interventions treatment Not Available completed NCT01870843
A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom treatment 4 completed NCT01814098
An Efficacy and Safety Study of Escitalopram Long-Term Treatment in Major Depressive Disorder With Associated Anxiety Symptoms treatment 4 completed NCT01744041
Mommy-Baby Treatment for Perinatal Depression No drug interventions treatment Not Available completed NCT01727726
A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial treatment 3 completed NCT01583400
Enhanced Collaborative Depression Treatment in Primary Care: The RESPECT-D-E Trial No drug interventions treatment Not Available completed NCT01564862
Efficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive Disorder treatment 2 completed NCT01460381
A Study to Evaluate the Effect of Genotype on LY2216684 treatment 1 completed NCT01460407
A Study to Evaluate the Effect of Clarithromycin on LY2216684 treatment 1 completed NCT01407575
Buprenorphine for Treatment Resistant Depression treatment 3 completed NCT01389765
A Study to Evaluate the Effect of Food on LY2216684 treatment 1 completed NCT01389752
A Study to Evaluate the Effect of Activated Charcoal on the Absorption of LY2216684 in Healthy Subjects treatment 1 completed NCT01360645
Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial) treatment 3 completed NCT01360632
Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial) treatment 3 completed NCT01331330
European Deep Brain Stimulation (DBS) Depression Study No drug interventions treatment Not Available completed NCT01284218
Retrospective Database Study of Real World Abilify Outcomes in Major Depressive Disorder (MDD) No drug interventions Not Available Not Available completed NCT01255787
Efficacy and Safety Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive Disorder treatment 2 / 3 completed NCT01163266
Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder treatment 3 completed NCT01155661
A Safety Study in Participants With Major Depressive Disorder treatment 3 completed NCT01153009
Safety and Efficacy of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder treatment 3 completed NCT01152996
Safety and Tolerability of Vortioxetine (LuAA21004) - Open Label Extension Study treatment 3 completed NCT01145313
Impact of Atypical Antipsychotic Therapy on Health Outcomes and Costs Among Patients With Major Depressive Disorder No drug interventions Not Available Not Available completed NCT01141387
Outcomes in MEasurement-Based Treatment No drug interventions Not Available Not Available completed NCT01141400
The Effect of Patient Cost-Sharing on Antidepressant and Adjunctive Therapy Use No drug interventions Not Available Not Available completed NCT01138007
A Fixed Dose Study of 323U66 SR in the Treatment of Major Depressive Disorder (MDD) No drug interventions treatment 3 completed NCT01129752
Mothers With a History of Depression and Their 10-14 Year Old Daughters No drug interventions Not Available Not Available completed NCT01106313
Insulin Resistance in Patients With Major Depression No drug interventions Not Available Not Available completed NCT00962598
The Role Of Omega-3 Fatty Acids In Adolescent Depression treatment 2 completed NCT00931619
GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression No drug interventions Not Available Not Available completed NCT00928980
Mindfulness Based Cognitive Therapy and Antidepressant Medication in Recurrent Depression No drug interventions treatment Not Available completed NCT00892463
Identifying Very Early Response to Seroquel Extended Release (XR) Augmentation for Major Depressive Disorder treatment 4 completed NCT00880399
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed Dose Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder treatment 2 terminated NCT00840034
A Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder treatment 2 completed NCT00733980
A Study of the Effects of a New Antidepressant Treatment (GSK561679) in Females With Major Depressive Disorder treatment 2 completed NCT00725270
Treatment of Schizoaffective Disorder Using Mifepristone treatment 2 / 3 terminated NCT00691535
Genetics of Symptomatology and Treatment Response in Psychotic Major Depression No drug interventions Not Available Not Available completed NCT00671515
Pioglitazone for the Treatment of Major Depressive Disorder Comorbid With Metabolic Syndrome treatment 2 completed NCT00636246
A Comparison of Sertraline-reboxetine Combination Therapy Versus Sertraline or Reboxetine Monotherapy in the Treatment of Major Depression. treatment 2 completed NCT00629551
An Eight-week Study of Saredutant and Paroxetine as Combination Treatment for Major Depressive Disorder treatment 3 completed NCT00627887
Randomised Controlled Trial of Electroconvulsive Therapy (ECT) in Relapse Prevention of Depression treatment 4 completed NCT00584974
A Safety, Efficacy and Tolerability Study of SEP-225289 treatment 2 completed NCT00559299
Patient Tolerability Study of GSK163090 No drug interventions treatment 1 completed NCT00551109
SA4503 8-Week Study in Major Depressive Disorder (MDD) treatment 2 completed NCT00456898
Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway treatment 1 completed NCT00451490
The Effect of Agomelatine or Fluoxentine on Heart Rate Variability in Patients With Major Depressive Disorder health_services_research Not Available withdrawn NCT00451516
St. John's Wort And Kava In The Treatment Of Major Depressive Disorder With Comorbid Anxiety treatment 2 completed NCT00440427
Study Evalutating the Pharmacokinetics (PK) and Safety of a Single Dose of Desvenlafaxine Sustained Release (DVS SR) treatment 1 completed NCT00421954
Open-label Ziprasidone Study for Psychosis Treatment in Adolescents treatment 3 completed NCT00406952
Study for Evaluating Different Methods of Measuring Depression Treatment Response treatment Not Available completed NCT00401726
Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program treatment 4 completed NCT00384033
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) In The Treatment Of Major Depressive Disorder treatment 3 completed NCT00370058
Study on the Influence of Electroconvulsive Therapy (ECT) on Homocysteine Levels No drug interventions diagnostic 4 completed NCT00369343
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women treatment 3 completed NCT00368303
A Local Register Study For Major Depression Of Paroxetine Controlled Release treatment 3 completed NCT00368030
A Study of Eszopiclone in Subjects With Insomnia Related to Major Depressive Disorder treatment 3 completed NCT00366652
Study Evaluating the Effects of DVS SR and Duloxetine on the Pharmacokinetics of Desipramine in Healthy Subjects treatment 3 completed NCT00300378
Study Evaluating the Efficacy and Safety of Desvenlafaxine Tablets in Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00285727
Ropinirole Controlled Release (CR) as an Adjunctive Agent in the Treatment of Major Depression treatment Not Available completed NCT00275197
A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD) treatment 2 completed NCT00246233
CONCERTA® (Methylphenidate Hydrochloride) as add-on Therapy in the Treatment of Adult Major Depressive Disorder. treatment 3 completed NCT00229450
Estrogen and Perimenopausal Depression treatment 4 completed NCT00227812
Integrated Treatment for Cocaine and Mood Disorders - 1 treatment 2 completed NCT00223288
Impact of Caregiver Depression on Asthma in the Child Not Available Not Available completed NCT00220636
Abilify as an Adjunctive Treatment for Refractory Depression treatment 4 completed NCT00218556
Preventing Depression in Methadone Maintenance Patients Receiving Hepatitis C Treatment - 1 No drug interventions prevention Not Available completed NCT00208156
A United States Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression treatment 3 completed NCT00191919
A Randomized Double Blind Study Evaluating Duloxetine in Outpatients With MDD and Pain treatment 3 completed NCT00191685
Duloxetine in the Treatment of Melancholic Depression treatment 3 completed NCT00186498
Memantine to Reduce Neurocognitive Deficits Following Unilateral ECT for the Treatment of a Major Depression prevention Not Available completed NCT00179062
Effects of Risperidone and Olanzapine on Patients With Schizophrenia, Schizoaffective Disorder, Major Depression or Bipolar Disorder treatment Not Available completed NCT00163059
The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDD treatment 2 completed NCT00149643
Effectiveness of Fluoxetine in Young People for the Treatment of Major Depression and Marijuana Dependence treatment 2 completed NCT00116077
Dopamine Receptor Imaging in Mood Disorders No drug interventions Not Available Not Available completed NCT00102492
Study Of GW679769 In Major Depressive Disorder treatment 2 completed NCT00097175
Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders No drug interventions Not Available Not Available completed NCT00093288
Major Depressive Disorder In The Elderly treatment 3 completed NCT00067444
Depression Study In Elderly Patients treatment 3 completed NCT00057213
An 8 Week Study Of Depression In Adults Diagnosed With Major Depressive Disorder treatment 2 completed NCT00048204
A Study Of A New Medicine (GW597599B) For The Treatment Of Major Depressive Disorder treatment 2 completed NCT06443216
Sleep Modulation to Treat Depression No drug interventions basic_science Not Available recruiting NCT00105196
A Study of Aripiprazole in Patients With Major Depressive Disorder diagnostic 3 completed NCT00188396
Effect of the Menstrual Cycle on the Symptoms of Depression and Treatment Response treatment Not Available completed NCT00963196
Study of Supplementation of Antidepressants With Fish Oil to Improve Time to Clinical Response supportive_care Not Available withdrawn NCT03645096
Development of Pregnenolone as a Treatment for Depression basic_science 1 completed NCT06350396
pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression No drug interventions treatment Not Available recruiting NCT00166296
Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C Patients prevention 2 completed NCT03357796
Relative Bioavailability (RBA) Study of LY03005 vs Pristiq® treatment 1 completed NCT03965858
Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression treatment 2 completed NCT04478058
Feasibility and Effectiveness of Delivering CBT Through OPTT for Depression No drug interventions treatment Not Available completed NCT01441258
Adaptation of Dialectical Behavior Therapy Skills-Groups for Individuals With Suicidal Ideation and Depression No drug interventions treatment Not Available completed NCT00672958
Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Adults With Major Depressive Disorder treatment 3 completed NCT04502758
Sequential Bilateral Accelerated Theta Burst Stimulation in Adolescents With Suicidal Ideation No drug interventions treatment Not Available recruiting NCT02992158
Feasibility of a Behavioral Activation Trial No drug interventions treatment Not Available completed NCT04366258
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression No drug interventions diagnostic Not Available completed NCT01234558
Single IV Dose of GLYX-13 in Patients With Treatment-Resistant Depression treatment 2 completed NCT05537558
Precision Medicine for the Prediction of Treatment (PROMPT) Response (PROMPT) No drug interventions Not Available Not Available unknown_status NCT02466958
Trial of Levomilnacipran in Geriatric Depression treatment 4 completed NCT05685758
A Treatment for Depression Via a Gamified Mobile Phone Application Based on a New Cognitive Model No drug interventions treatment Not Available completed NCT03122158
Escitalopram in the Treatment of Adolescents With Major Depressive Disorder or Anxiety Disorders treatment 4 unknown_status NCT02085135
A Study of Different Titration Schedules of ALKS 5461 in Adults With Major Depressive Disorder (MDD) No drug interventions treatment 3 completed NCT02724735
A Longitudinal Observational Cohort Study of NSI-189, With Out-Patients With Major Depressive Disorder Not Available Not Available unknown_status NCT03065335
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder treatment 1 recruiting NCT02934035
Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder Not Available Not Available unknown_status NCT05547035
Identification of Physiological Data by a Wearable Monitor in Subjects Suffering From Major Depression Disorders No drug interventions supportive_care Not Available recruiting NCT01221935
Retrospective Study Evaluating The Current Utilization Of Desvenlafaxine Succinate Sustained-Release (Pristiq) Among Psychiatrists And Primary Care Physicians In The Treatment Of Patients With Major Depressive Disorder No drug interventions Not Available Not Available completed NCT01454635
Analisis of Facors Involved in Antidepressant Treatment Response of Major Depressive Disorder treatment Not Available completed NCT01188135
Antidepressant Adherence Via AD_IVR No drug interventions treatment 3 completed NCT05630963
Beyond Monoamines: The Role of the Nociceptin/Orphanin FQ Receptor in Major Depression No drug interventions Not Available Not Available recruiting NCT00590863
Combining Medications to Enhance Depression Outcomes treatment 4 completed NCT04239963
Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression No drug interventions Not Available Not Available active_not_recruiting NCT02960763
Optimizing Outcomes of Treatment-Resistant Depression in Older Adults treatment 4 completed NCT01684163
Efficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to Antidepressants treatment 2 completed NCT04593563
The Safety and Efficacy of Psilocybin in Cancer Patients With Major Depressive Disorder treatment 2 unknown_status NCT04226963
A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders Not Available Not Available completed NCT01558063
Ketamine in the Treatment of Depression treatment 2 completed NCT02014363
Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD) treatment 2 completed NCT05224063
Probing the Dorsolateral Prefrontal Cortex and Central Executive Network for Improving Neuromodulation in Depression No drug interventions basic_science Not Available recruiting NCT02273063
rTMS for PTSD Comorbid With Major Depressive Disorder No drug interventions treatment Not Available completed NCT01204086
Pharmacogenomics Studies of Antidepressants treatment 4 unknown_status NCT02385786
Mindfulness-Based Cognitive Therapy Effect on Depression and C-Reactive Protein Levels After 8 Weeks of Treatment No drug interventions treatment Not Available completed NCT03468686
The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder No drug interventions treatment Not Available completed NCT00006286
Treatment for Adolescents With Depression Study (TADS) treatment 3 completed NCT03433339
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder No drug interventions treatment 1 / 2 completed NCT06029439
Study to Assess the Safety and Effectiveness of NMRA-335140-501 treatment 3 recruiting NCT05717439
Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults With PTSD No drug interventions Not Available Not Available recruiting NCT01703039
Riluzole Augmentation Pilot in Depression (RAPID) Trial treatment 2 terminated NCT02436239
A Study of Vilazodone in Pediatric Patients With Major Depressive Disorder treatment 3 completed NCT00933439
Assessment of Cognitive Functioning Before and After Treatment With Duloxetine treatment Not Available completed NCT02095639
Inflammation and Electroconvulsive Therapy No drug interventions Not Available Not Available terminated NCT06523439
Accelerated Intermittent Theta Burst in Treatment-Naive Adolescents No drug interventions treatment Not Available not_yet_recruiting NCT06247839
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder treatment 3 not_yet_recruiting NCT00531622
An Eight-week Study of Saredutant and Escitalopram as Combination Treatment for Major Depressive Disorder treatment 3 completed NCT02026622
Comparative Study of Physiological and Cerebrovascular Reactivity in Depression, at the Three Phases of Emotion No drug interventions basic_science Not Available completed NCT01995422
Effect of Physical Activity on Depressive Symptoms With a 5 Month Follow-up No drug interventions health_services_research Not Available completed NCT06515522
A Biological Signature for the Early Differential Diagnosis of Psychosis No drug interventions Not Available Not Available not_yet_recruiting NCT05925322
Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality No drug interventions treatment Not Available recruiting NCT00759122
Electroencephalography (EEG) Biomarkers of Response in Depression treatment 4 completed NCT06402422
Vulnerability Markers for Depression No drug interventions Not Available Not Available recruiting NCT04903522
Can the Affects Conveyed by Baroque Music Reduce Anxiety in Patients With Major Depressive Disorder ? No drug interventions basic_science Not Available completed NCT05693922
Augmenting Single-session Behavioral Activation (BA) With Delta-beta Transcranial Alternating Current Stimulation (tACS) for the Treatment of Depression No drug interventions treatment Not Available completed NCT03642522
Investigating Predictors of Treatment Response in Treatment-Resistant Depression (TRD) With Interleaved TMS/fMRI No drug interventions treatment Not Available completed NCT00668525
Escitalopram in Adult Patients With Major Depressive Disorder treatment 3 completed NCT06163625
The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression No drug interventions basic_science Not Available recruiting NCT00437125
Study on the Tolerability of Duloxetine in Depressed Patients With Parkinson's Disease treatment 4 completed NCT02311725
Storytelling Video Intervention for Depressed Primary Care Patients - Pilot Trial No drug interventions treatment Not Available completed NCT02922725
Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in Females treatment 4 terminated NCT03093025
A Study to Evaluate the Safety and Efficacy of TS-121 as an Adjunctive Treatment for Major Depressive Disorder treatment 2 terminated NCT00985725
SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder treatment 2 completed NCT04832425
A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder No drug interventions treatment 2 / 3 completed NCT05800925
Triage Survey for Psychiatry Research Eligibility No drug interventions Not Available Not Available recruiting NCT02925325
Music Therapy for Major Depressive Disorder Residual Symptoms No drug interventions treatment Not Available unknown_status NCT04933630
Tracking Response to Antidepressants in Advance of Investigational Trials, Relapse Study Not Available Not Available completed NCT03658330
Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder treatment 2 completed NCT04973930
Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast Cancer treatment 3 recruiting NCT04487730
Social Reward and Its Effect on Brain Functions in Psychotherapies for Mid- and Late-Life Depression No drug interventions treatment Not Available recruiting NCT03761030
L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults treatment 4 terminated NCT04221230
Study in Major Depressive Disorder With BTRX-335140 (NMRA-335140) vs Placebo treatment 2 completed NCT01263730
Tai Chi Training for Treating Depressed Chinese Americans No drug interventions supportive_care Not Available completed NCT02046330
Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression No drug interventions treatment Not Available active_not_recruiting NCT02669030
A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia treatment 4 unknown_status NCT01369030
Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support) No drug interventions Not Available Not Available completed NCT00035048
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-068)(COMPLETED) treatment 3 completed NCT04088448
The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients treatment 1 / 2 completed NCT01078948
Transcranial Direct Current Stimulation (tDCS) in the Treatment of Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT01528748
Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence No drug interventions Not Available Not Available completed NCT01975948
Evaluation of a Mental Health Physician Support Program in Nova Scotia No drug interventions health_services_research Not Available completed NCT00406848
A Study Comparing the Efficacy and Safety of Duloxetine and Placebo for the Treatment of Depression in Elderly Patients treatment 4 completed NCT00878748
Study Evaluating Effexor XR in Chinese Subjects With Major Depressive Disorder treatment 4 withdrawn NCT04061148
Near Infrared Spectroscopy (NIRS) for Assessment of Depression No drug interventions diagnostic Not Available recruiting NCT04685148
Maternal Mental Health Trial prevention 1 / 2 recruiting NCT00464048
A Controlled Study to Assess the Effectiveness of Aerobic Exercise as an Augmentation Therapy for Inpatients With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT01496248
Efficacy Study of Korean Red Ginseng to Treat Depression No drug interventions treatment Not Available completed NCT00125957
The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression treatment 3 completed NCT01860157
Deep rTMS for Treatment-Resistant Late-life Depression No drug interventions treatment Not Available completed NCT00075257
Study Evaluating DVS-233 SR In Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT01243957
A Study to Measure if There is Any Difference in How the Body Breaks Down or Inactivates Either Fluoxetine or LY2216684 When Both of These Medicines Are Given Together. treatment 1 completed NCT02728557
Supportive and Supportive-Expressive Treatment for Depression No drug interventions treatment Not Available unknown_status NCT00025857
Brain Function in Mentally Ill Adolescents No drug interventions Not Available Not Available completed NCT01432457
Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in Adult Outpatients With Major Depressive Disorder (MDD) treatment 4 completed NCT00018057
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders treatment 2 recruiting NCT00179257
The Effectiveness of Sertraline in Patients Who Have Had Inadequate Response to Escitalopram treatment 3 completed NCT04607226
Effects of Respiratory-Gated Transcutaneous Vagal Nerve Stimulation in Major Depression (Phase 1) No drug interventions other Not Available completed NCT02454426
Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease treatment 0 withdrawn NCT06029426
Study to Evaluate the Effects of Oral NMRA 335140 Versus Placebo in Participants With Major Depressive Disorder treatment 3 recruiting NCT01740726
Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression treatment Not Available terminated NCT06559826
Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression treatment 2 recruiting NCT04322526
Study of Naltrexone-Induced Blockade of Antidepressant Effects basic_science 4 completed NCT01667926
Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder treatment Not Available completed NCT01795326
Physician Survey on Monitoring of Patients Treated With Quetiapine No drug interventions Not Available Not Available completed NCT05802966
Cognition in Mindfulness: Negativity and Depression No drug interventions Not Available Not Available terminated NCT03404466
To Explore the Safety and Efficacy of Hypidone Hydrochloride Tablets in Treatment of Patients With MDD No drug interventions treatment 1 / 2 completed NCT06086366
Presynaptic Imaging in Major Depressive Episodes After COVID-19 No drug interventions Not Available Not Available recruiting NCT02460666
Brain Connectivity and Response to Tai Chi in Geriatric Depression No drug interventions supportive_care Not Available completed NCT03275766
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders No drug interventions basic_science Not Available completed NCT02279966
Efficacy of Vortioxetine on Cognitive Dysfunction in Working Patients With Major Depressive Disorder treatment 3 completed NCT04209166
A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical Features treatment Not Available unknown_status NCT04106466
DBS for TRD With the Medtronic Summit RC+S No drug interventions basic_science Not Available active_not_recruiting NCT00797966
Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder treatment 2 completed NCT05006365
EffectsOfTranscranialPulseStimulationOnDepression-PilotRCT No drug interventions treatment Not Available unknown_status NCT02421965
Comparing Mobile Health (mHealth) and Clinic-Based Self-Management Interventions for Serious Mental Illness No drug interventions treatment Not Available completed NCT05652465
Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder No drug interventions treatment 2 recruiting NCT03031665
Sex, Hormones and Gamma-Aminobutyric Acid (GABA) in Stress Induced Anhedonia in Depression No drug interventions Not Available Not Available completed NCT05573074
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression - R33 No drug interventions diagnostic Not Available recruiting NCT04972474
Exploring Engagement With Remote Symptom Tracking for Depression (RADAR: Engage) No drug interventions supportive_care Not Available unknown_status NCT01692574
Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD) No drug interventions treatment Not Available completed NCT03322774
Sleep To Reduce Incident Depression Effectively No drug interventions prevention Not Available active_not_recruiting NCT03421574
Trial of MR-guided Focused Ultrasound for Treatment of Refractory Major Depression No drug interventions treatment Not Available completed NCT06545474
Effects of rTMS Compared to SSRI as Early Treatment of Depression (Early-TMS) No drug interventions treatment Not Available not_yet_recruiting NCT00025974
Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder No drug interventions Not Available Not Available completed NCT00361374
Safety and Effectiveness of Omega 3-Fatty Acids, EPA Versus DHA, for the Treatment of Major Depression No drug interventions treatment 3 completed NCT06462820
SAINT for MDD in an Inpatient Setting Follow-on No drug interventions treatment 2 / 3 recruiting NCT00107120
The Safety and Efficacy of Escitalopram in Pediatric Patients With Major Depressive Disorder treatment 3 completed NCT00296920
Deep Brain Stimulation for Refractory Major Depression No drug interventions treatment 3 completed NCT01924520
Oral Multiple-dose Study in Patients With Major Depressive Disorder other 1 completed NCT03095820
Multidomain Intervention for Older Adults With Major Depressive Disorder No drug interventions treatment Not Available completed NCT01416220
Lithium Versus Paroxetine in Major Depression treatment 4 completed NCT05680220
40 Hz Light Neurostimulation for Patients With Depression (FELIX) No drug interventions treatment Not Available recruiting NCT00672620
Efficacy and Safety of Vortioxetine (Lu AA21004) in the Treatment of Patients With Major Depressive Disorder treatment 3 completed NCT06322420
Behavioral Activation for Depression and Habitual Rumination No drug interventions treatment Not Available recruiting NCT05086120
A Remote Electronically Delivered Integrated Care Pathway: A Feasibility Study No drug interventions treatment Not Available terminated NCT05435820
Near-infrared Transcranial Laser Therapy in Subjects With Major Depressive Disorder: A Study of Dosing With Laser No drug interventions treatment Not Available unknown_status NCT04142320
Closed-loop Optimized rTMS for Depression No drug interventions basic_science Not Available recruiting NCT01479920
A Positron Emission Topographic (PET) Study on Depression Patient With Electroacupuncture treatment Not Available completed NCT04637620
NMDA Modulation in Major Depressive Disorder treatment 2 recruiting NCT00035282
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-060)(COMPLETED) treatment 3 completed NCT01627782
A Study of Ketamine in Patients With Treatment-resistant Depression treatment 2 completed NCT04509882
Bear Bile Pill as add-on the Treatment of MDD No drug interventions treatment 2 unknown_status NCT04576182
Supportive-Expressive and Emotion-Focused Treatment for Depression No drug interventions treatment 3 recruiting NCT01887782
Randomized Controlled Trial of Conventional vs Theta Burst rTMS No drug interventions treatment Not Available completed NCT01447082
General Practice Research Database Seroquel XR Safety Study No drug interventions Not Available Not Available completed NCT02669082
The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy treatment 4 completed NCT02013531
Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms treatment 3 completed NCT01706731
Effectiveness of Buddhist Monks in Providing Cognitive Behavior Therapy No drug interventions treatment Not Available unknown_status NCT04751331
Neural Response to Inflammatory Challenge in Major Depressive Disorder No drug interventions basic_science 1 / 2 recruiting NCT02874131
Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD No drug interventions treatment Not Available completed NCT02181231
Buprenorphine Used With Treatment Resistant Depression in Older Adults treatment 1 / 2 completed NCT01134731
Paliperidone and Lithium in the Treatment of Suicidality - Treatment Indication and Epigenetic Regulation treatment 4 completed NCT06178731
Virtual Reality Reward Training and Transcranial Magnetic Stimulation for Depression No drug interventions other Not Available recruiting NCT01429831
Aripiprazole for the Augmentation of Antidepressant Therapy treatment 4 completed NCT00408031
D-cycloserine for Major Depressive Disorder treatment 2 completed NCT04448431
Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression treatment 4 completed NCT00927173
Evaluation of the Brainsway Deep Transcranial Magnetic Stimulation (TMS) H-Coil in the Treatment of Major Depression Disorder No drug interventions treatment Not Available completed NCT01101373
Treatment of Severe Depressive Illness by Targeted Brain Surgery No drug interventions Not Available Not Available completed NCT04747873
Incorporating Stepped Care Approach Into e-CBT for Depression No drug interventions treatment Not Available completed NCT01035073
Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome treatment 4 completed NCT03594773
Modeling Multi-level Dyadic Behavior to Transform the Science and Practice of Psychotherapy Process and Outcome. No drug interventions treatment Not Available completed NCT04543773
Individualized Targeting and Neuromodulation of Late-Life Depression No drug interventions treatment Not Available recruiting NCT00388973
Efficacy and Safety Study of Seroquel SR in the Treatment of Major Depressive Disorder treatment 3 completed NCT04210973
Comparison of Anyu Peibo With Placebo in Treatment of MDD in China No drug interventions treatment 3 unknown_status NCT01431573
Wake Therapy in the Treatment of Depression treatment Not Available completed NCT04461327
Psychophysiological Study of Pain Perception in Depressed Patients With Suicidal Risk basic_science Not Available recruiting NCT01856127
Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction? treatment 4 terminated NCT05181527
Repurposing of Dextromethorphan as an Adjunct Therapy in Patients With Major Depressive Disorder treatment 4 completed NCT02506127
Intermittent Theta Burst Stimulation for MDD No drug interventions treatment Not Available suspended NCT01447576
Study of Safety & Tolerability of OPC-34712 as Adjunctive Therapy in Treatment of Adult Patients With Major Depressive Disorder treatment 2 completed NCT05523076
Transdiagnostic Markers of Cognitive Symptoms in Disorders Affective. No drug interventions Not Available Not Available completed NCT05486676
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression No drug interventions treatment Not Available recruiting NCT02907476
The Treatment of Depression With Yoga and Walking No drug interventions treatment Not Available completed NCT04889976
Portable Transcranial Electrical Stimulation and Internet-Based Behavioral Therapy for Major Depression Study No drug interventions treatment Not Available completed NCT04855760
Safety of REL-1017 for Major Depressive Disorder treatment 3 completed NCT05243160
Medication Reviews in Severe Mental Illness No drug interventions health_services_research Not Available completed NCT06103760
Positioning of Esketamine Treatment in the Real-world Management of Depression treatment 4 recruiting NCT02309060
Storytelling Video Intervention for Depressed Primary Care Patients - Open Trial No drug interventions treatment Not Available completed NCT03811860
Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function No drug interventions treatment Not Available unknown_status NCT03742960
Sleep Subtypes in Adolescent Depression No drug interventions treatment Not Available completed NCT04529694
Patient Characteristics and Cognitive vs. Behavioral Therapies for Depression No drug interventions treatment Not Available completed NCT03615794
A Study of Pregnant and Postpartum Women With and Without Mood Disorders No drug interventions Not Available Not Available active_not_recruiting NCT00763594
Linköping University Relational and Interpersonal Psychotherapy Project No drug interventions treatment 2 terminated NCT01685294
Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression No drug interventions treatment 3 completed NCT00229294
Fibromyalgia in Men Suffering From PTSD No drug interventions Not Available Not Available completed NCT05577494
A Trial of Enhanced Versus Standard Measurement-Based Care Implementation for Depression No drug interventions Not Available Not Available unknown_status NCT03899194
Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive Disorder treatment Not Available unknown_status NCT04784494
MST for Parkinson's Disease No drug interventions treatment Not Available unknown_status NCT06145594
EMA-Guided Maintenance TMS for Depression No drug interventions prevention Not Available recruiting NCT02744391
A Study of L-DOPA for Depression and Slowing in Older Adults treatment 4 completed NCT06228391
Ketamine Treatment for PTSD and MDD in TBI treatment 2 not_yet_recruiting NCT03114891
Accelerated TMS to a Novel Brain Target in MDD and PTSD No drug interventions treatment Not Available completed NCT01812291
Evaluation of a Stepped Care Approach to Manage Depression in Diabetes No drug interventions treatment Not Available completed NCT05531591
RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT) treatment 4 active_not_recruiting NCT02332291
Connectivity Affecting the Antidepressant REsponse Study basic_science 4 completed NCT01934491
Cognitive Training for Depression II No drug interventions treatment Not Available completed NCT06232291
Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant Depression No drug interventions Not Available Not Available completed NCT02176291
Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine treatment 2 completed NCT02371291
Memory Flexibility Training for Depression No drug interventions treatment 1 / 2 completed NCT03893162
Gut Feeling: Understanding the Mechanisms Underlying the Antidepressant Properties of Probiotics No drug interventions basic_science Not Available completed NCT05535062
Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature No drug interventions treatment Not Available completed NCT06105762
Ketogenic Diet for Depression No drug interventions treatment Not Available not_yet_recruiting NCT00073762
Study Evaluating DVS-233 SR In Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT04040062
Spectral Correlation Coefficient-based TMS No drug interventions treatment Not Available enrolling_by_invitation NCT00882362
Long-Term Administration Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT03287362
Effects of Schema Therapy vs. Cognitive Behavioral Therapy vs. Individual Supportive Therapy No drug interventions treatment Not Available active_not_recruiting NCT00888862
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women treatment 3 unknown_status NCT02860962
A Trial of Dextromethorphan for Treatment of Major Depressive Disorder treatment 1 completed NCT06390462
Adolescent Interpersonal Counseling in Primary Care No drug interventions Not Available Not Available recruiting NCT01590862
ON/OFF Stimulation and Reward Motivation in Patients With Deep Brain Stimulators No drug interventions basic_science Not Available recruiting NCT01342380
Pioglitazone and Quetiapine XR Pharmacogenetic Study No drug interventions Not Available Not Available completed NCT01640080
A Study of the Efficacy of Intravenous Esketamine in Adult Patients With Treatment-Resistant Depression treatment 2 completed NCT06236880
A Phase 2a Study to Evaluate the Safety and Tolerability of GM-2505 in Patients With MDD No drug interventions treatment 2 recruiting NCT02371980
Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD) treatment 4 completed NCT00707980
Safety and Tolerability of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder treatment 3 completed NCT01997580
Electrophysiologic Parameters and Biomarkers Predicting Treatment Response in Patients With Major Depressive Disorder prevention 4 unknown_status NCT04641780
"Brexpiprazole (Rexulti™) Safety and Efficacy Among Filipino Patients (RAISE) - A Post Marketing Surveillance Program" Not Available Not Available unknown_status NCT01464229
Iloperidone Augmentation of SSRIs for Patients With Major Depressive Disorder With Residual Anger and Irritability treatment 4 completed NCT01075529
Early Prediction of Fluoxetine Response treatment 4 completed NCT00993629
Adjunctive Pregnenolone in Post-Traumatic Stress Disorder (PTSD) and Depression in Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans treatment 2 withdrawn NCT01882829
Nuedexta in Treatment-Resistant Major Depression treatment 2 completed NCT04727229
Stellate Ganglion Block for Major Depressive Disorder. other 4 completed NCT05386329
Therapist-Guided Smartphone-Delivered CBT for MDD No drug interventions treatment Not Available completed NCT02086929
Trazodone Once a Day in Major Depression Disorder treatment 3 completed NCT02644629
Intra-nasal vs. Intra-venous Ketamine Administration treatment 4 completed NCT03749629
Comparative Effectiveness of Pharmacogenomics for Treatment of Depression No drug interventions treatment Not Available completed NCT01700829
Ketamine in the Treatment of Suicidal Depression treatment 4 completed NCT02120729
Pharmacogenetic Decision Support IT System for Psychiatric Hospitalization: RCT No drug interventions treatment Not Available unknown_status NCT02674529
Study of Neural Responses Induced by Antidepressant Effects treatment 2 / 3 completed NCT01056289
Study Comparing Discontinuation Symptoms Of DVS SR In Subjects With Major Depressive Disorder (MDD) treatment 4 completed NCT02427789
Therapeutic Effectiveness of Exercise Associated to the Pharmacotherapy in Major Depression No drug interventions treatment Not Available completed NCT04388189
Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion treatment 4 withdrawn NCT02661789
Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression basic_science Not Available completed NCT01979289
Computerized Cognitive Remediation for Geriatric Depression No drug interventions treatment Not Available unknown_status NCT00620789
Behavioral Insomnia Therapy For Those With Insomnia and Depression treatment Not Available unknown_status NCT04117789
Feasibility of Internet-delivered CBT for Adolescents With Depression No drug interventions treatment Not Available completed NCT00529789
Open-Label Study of Duloxetine in the Treatment of Children and Adolescents With Major Depressive Disorder treatment 2 completed NCT00770289
Study Comparing Remission Rates, in Patients With Major Depressive Disorder (MDD) No drug interventions Not Available Not Available completed NCT00683592
Randomized, Double-Blind, Placebo Controlled Study of Vilazodone's Efficacy, Safety, and Biomarkers of Response in Major Depressive Disorder (MDD) treatment 3 completed NCT01878292
Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive Disorder treatment 3 completed NCT02082392
Developing New Clinical Management Strategies treatment 4 completed NCT01446692
Badalona Major Depressive Disorder Database Study No drug interventions Not Available Not Available completed NCT00824044
Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression health_services_research 4 completed NCT00109044
Comparison of Escitalopram Combination in Adult Patients With Major Depressive Disorder treatment 3 completed NCT04124744
A Pilot Randomised Controlled Trial of a Health Champion Intervention No drug interventions health_services_research Not Available unknown_status NCT00294944
The Effectiveness of Idazoxan in Treating TRD Not Available 3 withdrawn NCT03281044
Fecal Microbiota Transplantation in Depression treatment 2 terminated NCT01310140
Risks for Insulin Resistance and Metabolic Syndrome Between Major Depressive Disorder (MDD) or MDD With Psychotic Features No drug interventions Not Available Not Available terminated NCT05357040
Antidepressant Effects of Nitrous Oxide treatment 2 recruiting NCT01441440
Venlafaxine ER Phase 3 Study for Major Depressive Disorder (MDD) treatment 3 completed NCT01650740
Study of Placebo Without Deception Versus Standard Antidepressant for Major Depressive Disorder treatment Not Available terminated NCT01423240
Major Depressive Disorder With Mixed Features treatment 3 withdrawn NCT03163940
Laughter Yoga Intervention for People With Major Depressive Disorder No drug interventions health_services_research Not Available completed NCT06576440
Effects of Ghrelin Administration on Motivation basic_science Not Available enrolling_by_invitation NCT06328140
Sleep Quality, Cognitive Performance, and Computerized Cognitive Training Not Available Not Available not_yet_recruiting NCT01034267
Safety Study of F2695 SR in Major Depressive Disorder treatment 3 completed NCT05594667
Effect of SSRIs on Response to Psilocybin Therapy treatment 2 withdrawn NCT02722967
Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System treatment 2 completed NCT01764867
Algorithm Guided Treatment Strategies for Major Depressive Disorder treatment 4 unknown_status NCT05081167
A Study to Assess the Efficacy and Safety of REL-1017 as Monotherapy for Major Depressive Disorder (MDD) treatment 3 completed NCT01357967
The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope treatment 4 unknown_status NCT03062267
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness No drug interventions treatment Not Available completed NCT04181567
Comparison of the Efficacy, Safety, and Relapse of ECT to ECT Plus Agomelatine for Depressed Patients treatment 4 completed NCT03564067
MARt-Depression Trial No drug interventions treatment Not Available completed NCT03580967
Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes treatment 4 withdrawn NCT03766867
Vortioxetine Intravenous Infusion at Initiation of Oral Treatment With Vortioxetine in Patients With Depression treatment 2 completed NCT02583867
Predictors of Depression Treatment Response to Exercise No drug interventions treatment 3 completed NCT00787501
Imaging Antidepressant vs. Cognitive Behavior Therapy Effects on Unipolar Depression treatment 1 completed NCT04827901
XEN1101 for Major Depressive Disorder No drug interventions treatment 2 recruiting NCT01173601
A Fixed Dose Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder treatment 3 completed NCT05108701
Individual MBCT vs. CBT in Major Depression: A Pilot Study. No drug interventions treatment Not Available completed NCT01431001
Pilot Study in Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depression No drug interventions treatment Not Available completed NCT04317001
Treatment for Cognitive Impairment in Depression treatment 3 withdrawn NCT04591301
The Safety, Tolerability, and Pharmacokinetics Study of HEC113995 PA•H2O Tablets in Healthy Subjects No drug interventions treatment 1 completed NCT05812001
Exergames-acceptance and Commitment Therapy Program for Treatment of Major Depressive Disorder No drug interventions treatment Not Available not_yet_recruiting NCT00985504
A Study of Patients With Major Depressive Disorder and Residual Apathy treatment 4 completed NCT00420004
A Study for Participants With Major Depression treatment 2 completed NCT01380704
Safety and Pharmacodynamic Study of ABT-436 in Major Depressive Disorder No drug interventions treatment 1 completed NCT06532604
Study of Electrophysiological Markers of Antidepressants in Major Depressive Disorder No drug interventions treatment Not Available not_yet_recruiting NCT01409304
Effectiveness of Deep Transcranial Magnetic Stimulation in Depression No drug interventions treatment 2 / 3 completed NCT02502604
Cognitive Training Program for Individuals With Depression and Post-Traumatic Stress Disorder No drug interventions treatment Not Available completed NCT01299272
A Study in Prevention of Re-emergence of Depression Symptoms treatment 3 completed NCT02695472
Study of NSI-189 for Major Depressive Disorder treatment 2 unknown_status NCT05613972
Brief Suicide & Trauma Therapy for Suicide Risk No drug interventions treatment Not Available not_yet_recruiting NCT01148472
Efficacy and Tolerability of Escitalopram and Duloxetine in Outpatients With Major Depressive Disorder treatment 4 completed NCT04957368
Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial other 4 completed NCT06131268
The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN) treatment 4 recruiting NCT03175068
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response No drug interventions basic_science Not Available unknown_status NCT01487668
Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders No drug interventions health_services_research Not Available completed NCT05516368
TF-CBT for Long-term PTSD, Major Depressive Disorder and Anxiety Disorders in Victims of Terrorism No drug interventions treatment Not Available completed NCT03113968
ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) treatment 2 / 3 completed NCT05106868
Acupuncture for Patients With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT05633368
Impact of Covid-19 Pandemic on Patients Receiving Continuation or Maintenance Electroconvulsive Therapy No drug interventions Not Available Not Available completed NCT05148169
A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder No drug interventions treatment 4 unknown_status NCT05419869
Pilot Decentralized Trial No drug interventions treatment 2 completed NCT03716869
Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder No drug interventions screening Not Available completed NCT00998569
Neurocognitive Enhancement in Major Depressive Disorder No drug interventions treatment Not Available completed NCT05441969
In Vivo Cortical Excitability Modulation in Major Depressive Disorder No drug interventions Not Available Not Available recruiting NCT02999269
ECT Pulse Amplitude and Medial Temporal Lobe Engagement No drug interventions treatment 4 completed NCT02033369
Imaging Dopamine Release in Depression other 4 completed NCT00351169
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder treatment 3 completed NCT01583569
Complex Dynamic Systems in Mood Disorders No drug interventions Not Available Not Available completed NCT00810069
Early Versus Delayed Switch in Medication in Patients With Major Depressive Disorder treatment 4 completed NCT04158869
An Investigation of the Relationship Between Omega-3 Fatty Acid Nutrition and Mental Health in Children and Adolescents No drug interventions Not Available Not Available completed NCT06196346
Inter-Brain Synchrony in Psychotherapy for Depression No drug interventions basic_science Not Available recruiting NCT00205946
The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity treatment 1 completed NCT06267846
A Study to Evaluate the Efficacy and Safety of NBI-1070770 in Adults With Major Depressive Disorder No drug interventions treatment 2 recruiting NCT06001346
CBT+ for Depression No drug interventions treatment Not Available recruiting NCT04183946
Willkommen MutterglĂĽck: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety No drug interventions treatment Not Available unknown_status NCT06282146
Testing a Transdiagnostic TMS Treatment Target No drug interventions other 0 recruiting NCT00853346
Psychosocial Treatment of Depression in Parkinson's Disease No drug interventions treatment Not Available unknown_status NCT05570812
Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV treatment 2 recruiting NCT01808612
A Study of Fluoxetine in Major Depressive Disorder (MDD) Short-Term Dosing treatment 3 completed NCT01460212
Magnetic Resonance Imaging Study of Cognitive-Behavior Therapy for Major Depressive Disorder treatment 4 unknown_status NCT03571412
Antidepressive Effect on 5 Herz (Hz) rTMS Over Dorsomedial Prefrontal Cortex and Left Dorsolateral Prefrontal Cortex No drug interventions treatment Not Available completed NCT01189812
Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms treatment 2 completed NCT06254612
A Study of the Efficacy and Safety of SP-624 in the Treatment of Adults With Major Depressive Disorder No drug interventions treatment 2 recruiting NCT06163612
Effect of Suicidality on Social Cognition No drug interventions Not Available Not Available recruiting NCT01557712
Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks treatment 3 completed NCT05902312
Repetitive Versus Deep Transcranial Magnetic Stimulation for Major Depression No drug interventions treatment Not Available recruiting NCT06274112
Using TMS to Understand Neural Processes of Social Motivation No drug interventions basic_science Not Available not_yet_recruiting NCT05915312
Exosome for Early Diagnosis of Bipolar Affective Disorder No drug interventions Not Available Not Available not_yet_recruiting NCT00511810
Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder treatment 2 / 3 completed NCT02149810
Automatic Self Transcending Meditation Versus Treatment as Usual No drug interventions treatment Not Available completed NCT04969510
A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder No drug interventions treatment 2 completed NCT01468610
Neurocognition and Work Productivity in Major Depressive Disorder (MDD) treatment Not Available completed NCT01957410
A Study to Investigate Evoked Potentials as Markers of Ketamine-induced Cortical Plasticity in Patients With Major Depressive Disorder treatment 2 terminated NCT06372210
A Trial to Assess a Wearable Patch's Functioning to Detect Medication Ingestion other Not Available completed NCT03514810
Combined Sertraline and Ketoprofen Administration in Major Depressive Disorder treatment 1 completed NCT02079610
Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases No drug interventions treatment Not Available completed NCT02153281
Neuroimaging MAO-B in Medication Free TR-MDD Using Novel Tracer No drug interventions treatment Not Available completed NCT06293781
Application of the Web-based Acceptance and Commitment Therapy for Depression No drug interventions treatment Not Available recruiting NCT01355081
Efficacy Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive Disorder treatment 3 completed NCT00442481
Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder treatment 4 unknown_status NCT03138681
Rapid Antidepressant Effects of ATP and Phosphocreatine treatment 2 unknown_status NCT03780881
EXperimental Paradigm to Investigate Expectation Change in Depression 4 No drug interventions basic_science Not Available completed NCT03994081
Mechanism of Action of tACS for the Treatment of MDD No drug interventions basic_science Not Available completed NCT02150681
Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders No drug interventions treatment 1 completed NCT01473381
Safety and Efficacy of Vilazodone in Major Depressive Disorder treatment 4 completed NCT00523081
Study of Adolescence and Depression No drug interventions treatment 3 completed NCT03403881
Movement for Depression - An RCT Assessing the Effects of Physical Activity Promotion for People With MDD No drug interventions treatment Not Available unknown_status NCT03922581
Primary-Care Based Mindfulness Intervention No drug interventions treatment Not Available completed NCT01526395
Decreasing the Use of Unmodified Electroconvulsive Therapy (ECT) in an Indian Hospital supportive_care Not Available completed NCT04288895
Open-label, Flexible-dose Study of Vortioxetine in Patients With Depression in India treatment 4 completed NCT04317495
Augmenting rTMS With Cognitive Control Training in Major Depressive Disorder No drug interventions basic_science Not Available terminated NCT04216095
Comparative Effectiveness Clinical Trial of MST Compared to ECT in Major Depressive Disorder No drug interventions treatment 2 / 3 completed NCT01075295
Prevention of Weight Gain in Early Psychoses No drug interventions prevention Not Available completed NCT00234195
Wellbutrin XL, Major Depressive Disorder and Breast Cancer treatment 4 completed NCT06454695
Improving Treatment of Major Depressive Disorder by Reducing Negative Future-Oriented Mental Imagery No drug interventions treatment Not Available recruiting NCT01198795
Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder treatment 4 completed NCT00035295
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-061) treatment 3 completed NCT03722095
Research on the Effects of Combined Neurostimulation Protocols on Stress No drug interventions other Not Available completed NCT02418195
miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome basic_science 2 completed NCT03202095
Creatine for Treatment of Depression Associated With Type 2 Diabetes No drug interventions treatment 4 withdrawn NCT00290914
Safety and Efficacy Study of Vilazodone and Discovering Genetic Markers Associated With Response in Patients With Major Depressive Disorder treatment 2 completed NCT04623814
the Safety, Tolerability, and Pharmacokinetics Study of HEC113995 No drug interventions treatment 1 completed NCT03864614
A Study to Evaluate SAGE-217 in Adult Participants With Major Depressive Disorder (MDD) treatment 3 completed NCT05136755
NMDA Modulation in Antidepressant Nonresponders With Major Depressive Disorder No drug interventions treatment 2 recruiting NCT00909155
Brain Imaging Techniques That Predict Antidepressant Responsiveness basic_science Not Available completed NCT05625555
Predictors of Intravenous Ketamine Response in TRD treatment 3 recruiting NCT05773755
DBS for TRD With the Medtronic Percept PC No drug interventions basic_science Not Available recruiting NCT05990855
Using Sleep Wearables to Adapt Cognitive-behavioral Therapy for Insomnia in the Context of Depression (CBTiA) No drug interventions treatment Not Available not_yet_recruiting NCT05118750
ALTO-300 in Depression No drug interventions treatment 2 completed NCT05016050
Digital Therapeutic for Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) No drug interventions treatment Not Available completed NCT03957850
Cognitive Reappraisal in Adolescents With Major Depression No drug interventions treatment Not Available completed NCT04832750
Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep No drug interventions Not Available Not Available recruiting NCT03131050
Effectiveness Study of Scopolamine Combined With Escitalopram in Patients With MDD treatment 4 completed NCT04497350
Transcranial Magnetic Stimulation vs Theta Burst Stimulation in Major Depressive Disorder No drug interventions treatment Not Available enrolling_by_invitation NCT00939250
A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care No drug interventions treatment 4 completed NCT03769350
Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD) No drug interventions treatment Not Available withdrawn NCT05480150
Chinese Longitudinal and Systematic Study of Bioplar Disorder treatment Not Available recruiting NCT01263223
A Study of LY2216684 in Major Depressive Disorder in Patients Taking Selective Serotonin Reuptake Inhibitors treatment 1 completed NCT03711123
Group Metacognitive Therapy vs Clinical Management for Depression No drug interventions treatment Not Available recruiting NCT00839423
Randomised Placebo-controlled Venlafaxine-referenced Study of Efficacy and Safety of 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults treatment 2 completed NCT06391723
Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant Depression No drug interventions treatment Not Available not_yet_recruiting NCT05030623
The Phosphodiesterase Inhibitor Tadalafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients treatment 1 / 2 recruiting NCT00289523
EEG Biomarkers for Predicting Response to Antidepressant Therapy No drug interventions Not Available Not Available completed NCT04531423
PKC as Serum Biomarkers for Depression treatment Not Available unknown_status NCT00095823
A Study of Adjunctive Aripiprazole in Patients With Major Depressive Disorder treatment 3 completed NCT03072823
Omega-3 Polyunsaturated Fatty Acids on Major Depressive Disorder in Patients With Cardiovascular Diseases No drug interventions treatment Not Available completed NCT02048423
An Open Prospective Trial of IV Ketamine in Suicidal Adolescents treatment 2 / 3 unknown_status NCT03265808
Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression. No drug interventions treatment 1 / 2 recruiting NCT01882608
Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood Disorders No drug interventions prevention Not Available completed NCT04621708
Pilot Study of the Safety and Tolerability of L-DLPFC iTBS rTMS for MDD in MS No drug interventions treatment Not Available recruiting NCT02176408
Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression No drug interventions treatment Not Available completed NCT04441008
Accelerated iTBS for Depression and Suicidality No drug interventions treatment Not Available not_yet_recruiting NCT03295708
Fish Oil as Adjunct Treatment for Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT01717508
Neural Components Underlying the Treatment of Adolescent Depression No drug interventions treatment Not Available completed NCT02218008
A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - FORWARD-5 Study No drug interventions treatment 3 completed NCT02453438
Mood Patient Powered Research Network (MoodNetwork) No drug interventions Not Available Not Available completed NCT03674138
Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients No drug interventions supportive_care Not Available active_not_recruiting NCT01941043
A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Study of CERC-301 in the Adjunctive Treatment of Subjects With Severe Depression and Recent Active Suicidal Ideation Despite Antidepressant Treatment treatment 2 completed NCT04507243
Transcranial Direct Current Stimulation (tDCS) Therapy in Major Depression No drug interventions treatment Not Available completed NCT00608543
Aripiprazole Augmentation of SSRI Therapy in Treatment Refractory Depression treatment 4 completed NCT02838043
The Efficacy, Safety, and Tolerability of Probiotics on the Mood and Cognition of Depressed Patients No drug interventions treatment 3 completed NCT02579343
Adjunctive Treatment of Major Depression Utilizing Auricular Acupuncture treatment Not Available completed NCT01567943
Contingency Management of Alcohol Abuse in the Severely Mentally ILL No drug interventions treatment Not Available completed NCT05353543
Acupuncture Therapy Based on Biological Specificity of Acupoints for Major Depressive Disorder No drug interventions treatment Not Available not_yet_recruiting NCT05439603
ANC-501 in the Treatment of Adults With Major Depressive Disorder treatment 2 active_not_recruiting NCT02037503
The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression treatment 3 unknown_status NCT04698603
Clinical Study of GH001 in Depression treatment 1 / 2 completed NCT05312203
Alleviating Stress by Mobile Application' for Depression No drug interventions supportive_care Not Available recruiting NCT00367003
Deep Brain Stimulation for Treatment Resistant Depression No drug interventions treatment Not Available active_not_recruiting NCT01971203
Efficacy of Extended-release Quetiapine (Seroquel XR) as Adjunctive Therapy to Cognitive Behavioral Therapy in the Treat treatment Not Available completed NCT01397903
Description of Treatment Management of Patients With Major Depressive Disorder and Inadequate Response No drug interventions Not Available Not Available completed NCT05134103
Mindbeacon Therapist Assisted Internet Delivered CBT for Depression No drug interventions treatment Not Available withdrawn NCT00705003
Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD) treatment 2 completed NCT01699490
Role of Inflammation Factors and Insulin Resistance in Major Depressive Disorder treatment 4 unknown_status NCT00321490
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo and Active Control in Major Depressive Disorder treatment 3 completed NCT01920490
Blame Rebalance fMRI Feedback Proof-of-concept No drug interventions prevention Not Available completed NCT05425290
Emotion Regulation Training to Reduce Cardiovascular Disease Risk Among Depressed Young Adults in Southern Mississippi No drug interventions treatment Not Available completed NCT01360190
Neurophysiologic Monitoring of Antidepressant Treatment basic_science 4 completed NCT01369290
Electroencephalography (EEG) Signal Processing Not Available Not Available unknown_status NCT03666390
Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide treatment Not Available unknown_status NCT06266390
Individualized (fMRI-guided) TMS Treatment for Depression No drug interventions basic_science Not Available recruiting NCT05525390
Extended Reality Behavioral Activation: An Intervention for Major Depressive Disorder No drug interventions treatment Not Available completed NCT02458690
eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed Patients prevention 2 completed NCT03113890
McLean and Genomind Prospective Study No drug interventions supportive_care Not Available completed NCT04166864
Spectral Correlation Coefficient-determine TMS for Depression No drug interventions treatment Not Available enrolling_by_invitation NCT02046564
Assess the Efficacy and Safety of ASC-01 in Patients With Major Depressive Disorder No drug interventions treatment 3 completed NCT03771664
A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia treatment 3 terminated NCT02530164
Transcranial Direct Current Stimulation (tDCS) As Treatment for Major Depression No drug interventions treatment Not Available completed NCT00548964
Continuation Ketamine in Major Depression treatment 1 completed NCT04688164
A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD) treatment 3 completed NCT04714164
Cognitive Behavioral Therapy Group for Older Adults Delivered by Telethealth No drug interventions treatment Not Available terminated NCT00135421
Study of BMS-562086 in the Treatment of Outpatients With Major Depressive Disorder treatment 1 / 2 completed NCT03128021
Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO) treatment 4 completed NCT06537921
Comorbid Obesity and Depression With an Anti-inflammatory Medication other Not Available not_yet_recruiting NCT01371721
A 6-Month Open-Label Extension Study to the B2061014 Study to Evaluate the Safety, Tolerability and Efficacy of DVS SR in the Treatment of Children and Adolescents With MDD No drug interventions treatment 3 completed NCT05772221
The Role of Social Determinants in Cardiovascular Health and Vascular Function No drug interventions screening Not Available recruiting NCT04619121
Near-infrared Radiation-transcranial Photobiomodulation for Major Depressive Disorder No drug interventions treatment Not Available completed NCT04352621
Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD) treatment 4 unknown_status NCT03624621
Integral Remediation for Major Depression ("RehabilitaciĂłn Integral Para la DepresiĂłn Mayor", RIDEM) No drug interventions treatment Not Available completed NCT00035321
The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression treatment 3 completed NCT01931202
Mechanisms of Antidepressant Non-Response in Late-Life Depression treatment Not Available completed NCT04388202
Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram treatment 4 withdrawn NCT01803802
Effects of Early Abuse on Adult Intimate Relationships No drug interventions treatment Not Available completed NCT01601002
LEPR Polymorphism Weight Gain by Mirtazapine in Late Life Depression Not Available 4 completed NCT00566202
A Safety and Effectiveness Study of JNJ-18038683 in Patients With Moderate to Severe Depression treatment 2 completed NCT01110902
Efficacy, Safety and Tolerability of Agomelatine Sublingual Tablets in the Treatment of Major Depressive Disorder (MDD) treatment 3 completed NCT01710202
Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration Not Available Not Available completed NCT02959502
Home-Based CR and tDCS to Enhance Cognition in Persons With Mild Cognitive Impairment and Late Life Depression No drug interventions other Not Available active_not_recruiting NCT05411302
Augmenting Mental Health Support Through a Supportive Text Messaging Program No drug interventions supportive_care Not Available recruiting NCT04526002
The Utility of Concurrent TBS/fNIRS for Antidepressant Treatment Optimization No drug interventions basic_science Not Available recruiting NCT05537584
SMART Trial to Predict Anhedonia Response to Antidepressant Treatment treatment 4 recruiting NCT03452384
Acupuncture in Depression: From the Clinical Trial, Biomarkers to Molecular Biology No drug interventions treatment Not Available completed NCT04041284
A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder prevention 4 completed NCT02361684
e-Compared-S: Comparative Effectiveness Research on Internet-based Depression Treatment - Spanish Trial No drug interventions treatment Not Available completed NCT02980484
fMRI-neuronavigated rTMS for the Treatment of Major Depression Associated With TBI No drug interventions treatment 2 terminated NCT00592384
Project to Improve Symptoms and Mood in People With Spinal Cord Injury treatment 4 completed NCT05271084
Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder treatment 1 / 2 completed NCT04255784
High Dose Accelerated iTBS for Depression No drug interventions treatment Not Available recruiting NCT01121484
Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Peri- And Postmenopausal Women With Major Depressive Disorder (DVS 3364) treatment 4 completed NCT06013384
Low-Intensity Focused Ultrasound for Treatment-Resistant Depression No drug interventions treatment Not Available recruiting NCT06028984
Self-guided Treatment for Depression No drug interventions treatment Not Available active_not_recruiting NCT00593879
Flexible Dose Titration Add-on Study to Treat Major Depressive Disorder treatment 2 completed NCT03595579
Assessing Symptomatic Clinical Episodes in Depression treatment 2 completed NCT01537679
Meditation to Reduce Caregiver Stress No drug interventions supportive_care Not Available completed NCT03449979
Single Session of tACS in a Depressive Episode No drug interventions basic_science Not Available completed NCT00435279
A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and Insomnia treatment 3 completed NCT00714779
Fluoxetine vs. Brief Psychotherapy for Major Depression treatment Not Available completed NCT06093906
Positive Processes and Transition to Health (PATH) No drug interventions treatment Not Available not_yet_recruiting NCT06252701
Diet and Depression No drug interventions treatment Not Available recruiting NCT06462196
Natural History of Depression, Bipolar Disorder and Suicide Risk No drug interventions Not Available Not Available recruiting NCT04138680
Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression No drug interventions treatment Not Available completed NCT06570369
A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression No drug interventions treatment 1 recruiting NCT02607514
Hyperthermic Yoga for Depressive Symptoms No drug interventions treatment Not Available completed NCT03289923
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes No drug interventions treatment Not Available recruiting NCT05004987
Aβ Dynamics in LLMD treatment 4 recruiting NCT05172271
Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD No drug interventions device_feasibility Not Available recruiting NCT05434156
ELE-101 Safety & Tolerability Study in Healthy Participants and Patients With Depression No drug interventions treatment 1 / 2 recruiting NCT05603104
Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure treatment 3 recruiting NCT02752542
Personalized Indications for CBT and Antidepressants in Treating Depression No drug interventions treatment 4 recruiting NCT03327129
Identifying the Neural Basis of Capability for Suicide No drug interventions Not Available Not Available active_not_recruiting NCT03601026
Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use No drug interventions prevention Not Available recruiting NCT06564818
A Study of a Psilocybin Analog (CYB003) in Humans With Major Depressive Disorder No drug interventions treatment 3 not_yet_recruiting NCT03685942
Efficacy of Light Therapy Device LUMINETTE® in Major Depressive Disorder No drug interventions treatment Not Available completed NCT03693105
The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition No drug interventions treatment 2 / 3 recruiting NCT04678232
Positive Processes and Transition to Health No drug interventions treatment Not Available completed NCT04979910
Targeting IL-17A for Treatment-Resistant Depression treatment 2 recruiting NCT05347719
Virtual Mindfulness Training for Adults With History of Depression No drug interventions supportive_care Not Available completed NCT05603819
Clinical Validation Study for EDIT-B Test: an Aid for Differential Diagnosis of Bipolar Disorder, Based on RNA Editing Blood Biomarkers No drug interventions Not Available Not Available recruiting NCT05772702
Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Depression No drug interventions treatment Not Available active_not_recruiting NCT06309472
Trial of Mirtazapine for Depression in IBD treatment 2 recruiting NCT02727972
Examination of Glutamate and mGluR5 in Psychiatric Disorders No drug interventions other Not Available recruiting NCT02734602
Imaging SV2A in Mood Disorders basic_science Not Available recruiting NCT04209296
Chart Review of Patients Undergoing Ketamine Infusions Not Available Not Available completed NCT04466345
Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder treatment 2 active_not_recruiting NCT05524519
Intradermal Acupuncture Based on Changes in Biological Specificity of Acupoints for Major Depressive Disorder No drug interventions treatment Not Available completed NCT05645575
In-patient SCC TMS No drug interventions treatment Not Available enrolling_by_invitation NCT05725785
Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness No drug interventions supportive_care Not Available recruiting NCT05877885
Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics No drug interventions treatment Not Available not_yet_recruiting NCT05989412
Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population. No drug interventions screening Not Available not_yet_recruiting NCT06548113
Sensory Synchronized Imaging and Neuromodulation No drug interventions basic_science Not Available not_yet_recruiting NCT06550037
Optimize and Predict Antidepressant Efficacy for Patient With MDD Using Multi-omics Analysis and AI-predictive Tool No drug interventions Not Available Not Available recruiting NCT06542094
Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation No drug interventions treatment Not Available recruiting NCT03697603
A Study of Brexpiprazole in Patients With Major Depressive Disorder treatment 2 / 3 completed NCT04479852
A Study of the Safety and Efficacy of SP-624 in the Treatment of Adults With Major Depressive Disorder No drug interventions treatment 2 completed NCT05409794
Basal Plasma Lithium Levels and Suicidal Events No drug interventions Not Available Not Available recruiting NCT05697172
Low Intensity Ultrasound Neuromodulation of Repetitive Negative Thinking In Depression No drug interventions other Not Available completed NCT06547489
GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder treatment 2 not_yet_recruiting NCT06009003
Individual Patient Esmethadone (REL-1017) Expanded Access Program Not Available Not Available temporarily_not_available NCT06058013
Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder treatment 3 recruiting NCT06058039
Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder treatment 3 recruiting NCT06391593
PD, PK, and Safety of ALTO-203 in Patients With MDD No drug interventions treatment 2 recruiting NCT06419608
Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression No drug interventions treatment 2 recruiting NCT06423781
Long-term Safety Study of BHV-7000 in Participants With Major Depressive Disorder (MDD) No drug interventions treatment 2 enrolling_by_invitation NCT06529029
Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy No drug interventions treatment 2 / 3 recruiting NCT03632434
Transcranial Direct Current Stimulation Therapy for Major Depression No drug interventions treatment Not Available completed NCT04225624
Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts No drug interventions treatment Not Available recruiting NCT04604210
Symptom-specific TMS Targets for Depression and Anxiety No drug interventions treatment 2 completed NCT05165394
Study to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDD No drug interventions treatment 2 completed NCT05194098
Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression No drug interventions basic_science Not Available recruiting NCT05399498
Psilocybin in Co-occuring Major Depressive Disorder and Borderline Personality Disorder treatment 2 recruiting NCT05932407
A Database Survey of Comparison The Risk of Haemorrhage Between Vortioxetine Tablet Treatment and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment in Participants With Depression Not Available Not Available completed NCT06011577
Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDD treatment 3 recruiting NCT06080646
Reward Processing and Depressive Subtypes: Identifying Neural Biotypes No drug interventions Not Available Not Available recruiting NCT06357832
New Investigational Stimulation Protocol for Treatment of Major Depression Disorder (MDD) No drug interventions treatment Not Available recruiting NCT06518642
Transcranial Direct Current Stimulation (tDCS) in Young Individuals With Major Depressive Disorder: a Literature Review and Feasibility Study No drug interventions treatment Not Available completed NCT04395183
5-HTP and Creatine for Depression No drug interventions treatment 2 completed NCT04821271
Antidepressant Effects of TS-161 in Treatment-Resistant Depression No drug interventions treatment 2 completed NCT04855747
A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD) treatment 3 recruiting NCT05227612
Psilocybin-assisted CBT for Depression treatment 0 recruiting NCT05437705
Decoding and Modulating Affective Brain States No drug interventions basic_science Not Available recruiting NCT05675800
Psilocybin for Major Depressive Disorder treatment 2 withdrawn NCT05712187
Phase 2b Study of ALTO-100 in MDD No drug interventions treatment 2 active_not_recruiting NCT05893173
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Sleep Deprivation No drug interventions Not Available Not Available recruiting NCT05973851
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. treatment 3 recruiting NCT06132178
Psilocybin rTMS for Treatment Resistant Depression treatment 2 not_yet_recruiting NCT06402955
Imaging Depression in Parkinson's Disease No drug interventions Not Available Not Available not_yet_recruiting NCT06512324
Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness Registry No drug interventions Not Available Not Available enrolling_by_invitation NCT03804619
Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder No drug interventions treatment Not Available withdrawn NCT06507787
Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects No drug interventions diagnostic Not Available not_yet_recruiting NCT05437588
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents No drug interventions prevention Not Available recruiting NCT03573349
Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: treatment 0 active_not_recruiting NCT03859297
Mechanisms of Rumination Change in Adolescent Depression No drug interventions prevention Not Available recruiting NCT04183205
Predicting SSRI Efficacy in Veterans With PTSD screening 4 recruiting NCT04990687
Vagal Nerve Stimulation for Treatment Resistant Major Depression No drug interventions treatment Not Available completed NCT05061706
Multicenter Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder treatment 3 completed NCT05084924
Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia No drug interventions basic_science Not Available completed NCT05528718
SMILE Trial - Imaging Sub-Study Not Available Not Available completed NCT06476509
A Study to Assess Serotonin Transporter Occupancy of Healthy Adults Using 11C-DASB PET treatment 1 not_yet_recruiting NCT05855850
Deep rTMS for Depression in Older Adults No drug interventions health_services_research Not Available completed NCT06072898
A Randomized Neuroimaging Trial of Psilocybin in Depression basic_science 2 not_yet_recruiting NCT06399406
Mindfulness Engaged Neurostimulation for Depression No drug interventions treatment 2 recruiting NCT06451809
Prediction of the Response to a Course of Transcranial Magnetic Stimulation (rTMS) Based on Heart Rate Variability No drug interventions Not Available Not Available recruiting NCT06451835
Evaluation of Response to a Course of Repetitive Transcranial Magnetic Stimulation Using Vocal Biomarkers No drug interventions Not Available Not Available recruiting NCT06480201
Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression other 1 recruiting NCT06480500
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial treatment 2 recruiting NCT05327699
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine other 0 recruiting NCT05538910
Defining Neurobiological Links Between Substance Use and Mental Illness basic_science Not Available recruiting NCT05657691
Xanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD) No drug interventions treatment 2 completed NCT05708976
HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2 No drug interventions treatment Not Available active_not_recruiting NCT05859698
Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia treatment 4 active_not_recruiting NCT05866575
Prediction of the Therapeutic Response in Depression Based on Neuro-computational Modeling Assessment of Motivation No drug interventions treatment Not Available recruiting NCT05895747
5-HTP and Creatine for Depression R33 Phase treatment 2 recruiting NCT05922878
Study of ALTO-300 in MDD No drug interventions treatment 2 recruiting NCT06002100
Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements No drug interventions Not Available Not Available enrolling_by_invitation NCT06230757
Psilocybin for Treatment-Resistant Depression treatment 2 enrolling_by_invitation NCT06332261
Standardized Assessment in Depression Treatment in Routine Psychiatric Services No drug interventions Not Available Not Available active_not_recruiting NCT06477276
Amygdala TIS for Depression No drug interventions treatment Not Available recruiting NCT05041361
HypErthermia as an Additional Treatment for the Biology and Experience of Depression No drug interventions treatment Not Available completed NCT05553691
SPL026 With or Without SSRIs in Participants With MDD treatment 1 completed NCT05837351
The CARE (Collaborative Adolescent Running Experience) Project No drug interventions treatment Not Available completed NCT06323785
Whole-body Hyperthermia for Depression No drug interventions treatment Not Available recruiting NCT06372834
Adjuvant Accelerated piTBS for Reducing Suicidal Ideation in TRD Patients No drug interventions treatment Not Available recruiting NCT06450704
Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive Disorders No drug interventions treatment Not Available not_yet_recruiting NCT06452290
PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder No drug interventions diagnostic Not Available not_yet_recruiting NCT06452849
Amygdala and dLPFC MRI-TIS for Depression in Adolescents No drug interventions treatment Not Available recruiting NCT06461260
Amygdala MRI-TIS for Depression No drug interventions treatment Not Available recruiting NCT04358900
Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK) No drug interventions Not Available Not Available active_not_recruiting NCT04711005
Phase 1 Evaluation of (2R,6R)-Hydroxynorketamine No drug interventions treatment 1 completed NCT05487911
Cortical rTMS as a Treatment for Depression No drug interventions treatment Not Available enrolling_by_invitation NCT05615948
Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression treatment 4 completed NCT05671419
Mindful Self-Compassion for Anxiety Disorders and Depression No drug interventions treatment Not Available recruiting NCT05933148
Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression No drug interventions treatment Not Available recruiting NCT06439043
Cultural Adaptation of EMDR for Major Depressive Disorder and Compaire Its Online and Face-to-Face Testing No drug interventions treatment Not Available not_yet_recruiting NCT06439797
Inflammatory Markers as Predictors of the Efficacy of Electroconvulsive Therapy (ECT) in Major Depression Patients No drug interventions Not Available Not Available completed NCT06443242
Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive Disorder No drug interventions treatment Not Available not_yet_recruiting NCT03554174
Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder treatment 1 active_not_recruiting NCT04116528
Opiate Suicide Study in Patients With Major Depression treatment 3 recruiting NCT05593029
A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder treatment 2 / 3 recruiting NCT06110897
RESISTance Exercise for Depression Trial No drug interventions treatment Not Available recruiting NCT06126497
Study Evaluating Safety and Efficacy of Ropanicant in MDD Patients treatment 2 active_not_recruiting NCT06426485
To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets No drug interventions treatment 4 not_yet_recruiting NCT05431374
Measurement-Based Care Vs. Standard Care for Major Depressive Disorder No drug interventions treatment 3 completed NCT05536414
Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive Disorder treatment 2 recruiting NCT05809609
Glutamate Emotion Memory Study basic_science Not Available recruiting NCT00784199
Validating PROMIS Instruments in Depression No drug interventions Not Available Not Available completed NCT04328103
Mechanisms of Emotion Regulation Underlying Successful CBT in Depression No drug interventions Not Available Not Available completed NCT05523817
Targeting Specific Brain Networks to Treat Specific Symptoms in Depression No drug interventions other Not Available recruiting NCT06223880
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms treatment 4 recruiting NCT06345859
Regulation of Affect and Physiology in Depression No drug interventions basic_science 2 recruiting NCT06410599
Pharmacologic Treatment Augmentation in Chronic Depression treatment 2 not_yet_recruiting NCT06417437
Non-invasive BCI and Application Verification for Depressed People No drug interventions treatment 4 recruiting NCT03953014
Pharmacogenetics of Antidepressant-Induced Disinhibition No drug interventions Not Available Not Available recruiting NCT04721249
D-serine Supplementation for Depression No drug interventions treatment Not Available completed NCT04770285
Trial to Evaluate the Effectiveness of a Digital Therapeutics in Adults Diagnosed With Major Depressive Disorder No drug interventions treatment 3 completed NCT04780542
Internet-delivered Cognitive Behavioral Treatment of Depression and Anxiety in Latin American College Students No drug interventions treatment Not Available active_not_recruiting NCT05046184
Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets other 2 recruiting NCT05051618
Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis No drug interventions treatment Not Available recruiting NCT05193318
KAP for Depression in Abstinent Opioid Users treatment 2 terminated NCT05703256
Amygdala Neurofeedback for Depression - Large Scale Clinical Trial No drug interventions treatment Not Available recruiting NCT05710887
N2O for Acute Suicidality and Depression in the ED treatment 2 not_yet_recruiting NCT05950009
Relationship Between Major Depression and Periodontal Diseases No drug interventions Not Available Not Available recruiting NCT06076317
Relevance of a Telemedicine Monitoring in the Management of Depression No drug interventions supportive_care Not Available recruiting NCT06404320
Physical Activity Program for TRD No drug interventions treatment Not Available not_yet_recruiting NCT03737474
A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder treatment 3 completed NCT03898297
Imaging mGluR5 and Synaptic Density in Psychiatric Disorders No drug interventions Not Available Not Available recruiting NCT04977856
Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression No drug interventions treatment Not Available active_not_recruiting NCT05384405
aiTBS for Relieving NSSI in Depressive Patients No drug interventions treatment Not Available recruiting NCT05921929
First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) No drug interventions other 1 withdrawn NCT03481049
Individualizing Incentives for Alcohol in the Severely Mentally Ill No drug interventions treatment Not Available active_not_recruiting NCT03437928
Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting No drug interventions treatment Not Available recruiting NCT03774641
A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women Not Available Not Available recruiting NCT04041479
Biomarker-guided rTMS for Treatment Resistant Depression No drug interventions treatment 3 recruiting NCT04518592
Model-based Defining of Subtypes of Depression and Optimal Treatment: an Integrated Techniques Module. No drug interventions Not Available Not Available recruiting NCT04985942
Clinical Trial of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder treatment 3 completed NCT05157945
ALTO-300 in Depression (ALTO-300-004) No drug interventions treatment 2 completed NCT05239780
Invasive Decoding and Stimulation of Altered Reward Computations in Depression No drug interventions treatment Not Available recruiting NCT06159595
Behavioral and Neuronal Correlates of Human Mood States No drug interventions basic_science Not Available recruiting NCT06384209
The Friendship Bench Plus Trial treatment Not Available not_yet_recruiting NCT04630964
The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density treatment 2 completed NCT05136365
A Study of Xiongdan Wan Treating Depression No drug interventions treatment 2 completed NCT05194267
Intensive tDCS for MDD: Feasibility Study No drug interventions treatment Not Available completed NCT05320107
The Effect of Ketamine on Aesthetics and Role for Antidepressant Effects basic_science 1 recruiting NCT05988619
iCBT With TMS in Patients With MDD No drug interventions treatment Not Available active_not_recruiting NCT06054321
Psychopharmacotherapy for Depressive Patients treatment Not Available recruiting NCT06376734
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness No drug interventions basic_science 2 not_yet_recruiting NCT03979040
Comparing Group Therapies for Veterans With Depression and PTSD No drug interventions treatment Not Available completed NCT04448327
Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression No drug interventions basic_science Not Available recruiting NCT04825535
Non-Inferiority RCT Comparing Online and On-Site CBT in MDDi No drug interventions treatment Not Available suspended NCT04923685
MicroRNA Correlates of Childhood Maltreatment and Suicidality No drug interventions Not Available Not Available recruiting NCT05273996
Predictors of Cognitive Outcomes in Geriatric Depression other 4 recruiting NCT05733546
A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder treatment 2 recruiting NCT06336616
Getting Out of the House: Using Behavioral Activation to Increase Community Participation No drug interventions supportive_care Not Available recruiting NCT06360419
Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol treatment 3 recruiting NCT04014959
Mini Theta Burst TMS in MDD Patients No drug interventions basic_science Not Available completed NCT04632498
Investigating Biological Markers, Targets, and Intervention for Mood Disorders No drug interventions basic_science Not Available terminated NCT05317481
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms No drug interventions prevention Not Available recruiting NCT05388539
TBS Treatment for Treatment-Resistant Depression No drug interventions treatment Not Available completed NCT06309277
A Clinical Study to Evaluate of Single and Multiple Oral Doses of GM-1020 in Patients With MDD No drug interventions treatment 2 recruiting NCT06341426
Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin treatment 2 recruiting NCT06345651
Brain Oscillation-synchronized Stimulation of the Frontal Cortex in Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT04589143
A Double-blind, Placebo-controlled Study of Antidepressant Augmentation With Agomelatine treatment 4 completed NCT05666687
An Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the Brain No drug interventions basic_science 1 completed NCT04296604
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations No drug interventions treatment Not Available recruiting NCT04392947
Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation No drug interventions treatment Not Available recruiting NCT04530942
The Efficacy and Prediction of Deep Brain Stimulation for Treatment-resistant Depression No drug interventions treatment Not Available active_not_recruiting NCT04673383
SPL026 (DMT Fumarate) in Healthy Subjects and MDD Patients treatment 1 / 2 completed NCT05142683
Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial No drug interventions treatment Not Available recruiting NCT05203341
Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD) treatment 2 completed NCT05385783
A Study of a Psilocybin Analog (CYB003) in Healthy Participants With and Without Major Depressive Disorder No drug interventions treatment 1 / 2 completed NCT05644093
IM and IV SPL026 Drug Product in Healthy Participants No drug interventions treatment 1 completed NCT06271954
The Relationship Between Emotion Regulation and Psychiatric Disorder in Youth No drug interventions Not Available Not Available recruiting NCT06329414
Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple Sclerosis No drug interventions Not Available Not Available recruiting NCT06331572
Exploring Blood Plasma Metabolomics: Unraveling the Metabolic Landscape in Treatment-Resistant Adolescent Depression No drug interventions Not Available Not Available completed NCT03821506
ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients No drug interventions treatment Not Available completed NCT03787290
Mild-Intensity Whole Body Hyperthermia (WBH) for Major Depressive Disorder treatment 2 suspended NCT04952532
A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic No drug interventions other Not Available recruiting NCT05376150
A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder No drug interventions treatment 2 completed NCT06050070
Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback No drug interventions basic_science Not Available recruiting NCT06114342
The Biological Specificity of Acupoints Between Major Depressive Disorder Patients and Healthy Controls No drug interventions Not Available Not Available completed NCT04278521
Mechanism of Action of Transcranial Magnetic Stimulation No drug interventions treatment Not Available active_not_recruiting NCT05017311
Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D) treatment 4 recruiting NCT05384041
Cranial Electrotherapy Stimulation for the Treatment of Major Depressive Disorder in Adults No drug interventions treatment Not Available completed NCT05811897
RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault No drug interventions treatment Not Available recruiting NCT06306248
Immune Activation, Neural Plasticity and Depression No drug interventions Not Available Not Available recruiting NCT06306209
Inflammatory Control of Antidepressant Efficacy: a Pharmaco-epigenetic Approach No drug interventions Not Available Not Available recruiting NCT03833206
A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients No drug interventions treatment 1 / 2 not_yet_recruiting NCT04345471
A Study of MD-120 in Patients With Depression treatment 3 completed NCT04556890
Pain and Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT04587778
Imaging Neural Correlates of Ketamine Using PET/MR basic_science 1 recruiting NCT04638231
Supportive Text Messaging Versus Supportive E-mail Messaging for Patients With Major Depressive Disorder No drug interventions supportive_care Not Available completed NCT04785456
rTMS for Suicidality in Opioid Use Disorder No drug interventions treatment Not Available completed NCT04972136
rTMS for Depression in Young Adults With Autism No drug interventions treatment Not Available recruiting NCT05426265
The Effects of Videogames on Depression Symptoms and Brain Dynamics No drug interventions treatment Not Available active_not_recruiting NCT05695365
Feasibility of Resistance Exercise to Treat Major Depression Via Cerebrovascular Mechanisms No drug interventions treatment Not Available completed NCT05757791
Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD) treatment 2 recruiting NCT06003309
Frequency and E-field Enhancement of ITBS for Depression (FREED) No drug interventions treatment Not Available recruiting NCT06235905
Open-Label of SPN-820 in Adults With Major Depressive Disorder treatment 2 recruiting NCT06229652
Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain Correlates No drug interventions health_services_research Not Available not_yet_recruiting NCT06299787
Cognitive Dysfunction in the Addictions Study - Project 4 (P4) No drug interventions treatment Not Available recruiting NCT03708159
Maintenance of Response After rTMS for Depression Using tDCS No drug interventions treatment Not Available completed NCT04032301
Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans diagnostic 1 recruiting NCT04384965
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic No drug interventions treatment Not Available completed NCT05720637
The Efficacy and Cerebral Mechanism of Intradermal Acupuncture for Major Depressive Disorder treatment Not Available completed NCT05819021
Open Label Optimization Study No drug interventions Not Available Not Available recruiting NCT04293341
Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder No drug interventions treatment Not Available recruiting NCT06213324
Neural Circuit Effects of Ketamine in Depression basic_science 4 recruiting NCT06255561
pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression No drug interventions treatment Not Available not_yet_recruiting NCT04276259
Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses other 4 recruiting NCT05271357
Transcranial Magnetic Stimulation for Depression in Autism Spectrum Conditions No drug interventions treatment Not Available completed NCT05701345
Study of Virtual Reality-based Medical Device for Patients With Depressive Disorder No drug interventions treatment Not Available enrolling_by_invitation NCT05964036
pBFS-guided High-dose TMS Over DMPFC for Treatment-resistant Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT05976022
pBFS Guided rTMS Therapy Over Different Targets for Treatment-Resistant Depression No drug interventions treatment Not Available recruiting NCT05976009
pBFS-Guided rTMS Therapy Over Different Targets for Treatment-Resistant Depression No drug interventions treatment Not Available recruiting NCT06095778
rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFS No drug interventions treatment Not Available recruiting NCT06112652
Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique No drug interventions treatment Not Available recruiting NCT03152409
Salicylic Augmentation in Depression treatment 2 terminated NCT03363919
Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression No drug interventions treatment Not Available completed NCT03688139
Reward Function and Therapy for Late-Life Depression No drug interventions treatment Not Available completed NCT04410341
The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients treatment 1 / 2 active_not_recruiting NCT04832178
Sumor as Adjuvant Therapy in Treatment-resistant Major Depression No drug interventions treatment 4 recruiting NCT04830215
Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder treatment 4 completed NCT05892744
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression treatment 4 recruiting NCT06132581
Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic Depression No drug interventions basic_science Not Available recruiting NCT06211140
Transcranial Alternating Current Stimulation (tACS) on Serotonin-1A Receptor in Depression No drug interventions treatment Not Available recruiting NCT06234176
Impact of Psychomotor Therapy on the Quality of Life in Depression No drug interventions supportive_care Not Available not_yet_recruiting NCT01506206
ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators No drug interventions Not Available Not Available withdrawn NCT04724447
ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION treatment 1 / 2 recruiting NCT05591677
D-Cycloserine Augmentation of Intermittent Theta Burst Stimulation (iTBS) in Depression (COGENT) treatment 2 recruiting NCT04621786
Electroconvulsive Therapy Amplitude Titration No drug interventions treatment Not Available completed NCT04711915
Fixed Order, Open-Label, Dose-Escalation Study of DMT in Humans other 1 active_not_recruiting NCT04953208
Remotely Non-invasive Brain Stimulation and Videogame to Alleviate Depression No drug interventions treatment Not Available recruiting NCT04975724
Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder treatment 4 recruiting NCT05686668
Evolution of the Sensory Profile in Depression No drug interventions Not Available Not Available enrolling_by_invitation NCT06003361
Rise Study for Depression No drug interventions treatment Not Available completed NCT06203015
The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder No drug interventions Not Available Not Available recruiting NCT05571878
Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents basic_science Not Available recruiting NCT05850689
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder treatment 3 recruiting NCT04410575
Mental Health Assessment and Prescribing by Alberta Pharmacists No drug interventions treatment Not Available recruiting NCT05009511
MRI Markers of Feedback Timing During Learning in Individuals With TBI With and Without Clinical Depression No drug interventions basic_science Not Available recruiting NCT06183359
Self-Identification Program No drug interventions prevention Not Available not_yet_recruiting NCT03915613
Brain Insulin Resistance in Mood Disorders treatment 1 / 2 recruiting NCT03096886
Novel Neural Circuit Biomarkers of Major Depression Response to CCBT No drug interventions treatment Not Available active_not_recruiting NCT03505905
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression treatment 1 / 2 recruiting NCT04721678
Internet-administered Interpersonal Psychotherapy for Depressive Symptoms No drug interventions treatment Not Available completed NCT05948839
pBFS Guided rTMS Over DMPFC for Treatment-Resistant Depression No drug interventions treatment Not Available recruiting NCT06168175
Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive Disorder treatment 2 not_yet_recruiting NCT03736538
Nitrous Oxide- Suicidal Ideation treatment 1 enrolling_by_invitation NCT04504253
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder No drug interventions treatment 3 completed NCT04620759
Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder treatment 2 recruiting NCT05530642
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel No drug interventions supportive_care Not Available active_not_recruiting NCT05655507
Zuranolone Pharmacokinetics (PK) and Safety Study Adolescent Participants With Major Depressive Disorder (MDD) treatment 1 recruiting NCT05996900
Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans No drug interventions basic_science Not Available active_not_recruiting NCT00514865
Placebo-Controlled Study of ONO-2333Ms in Patients With Recurrent Major Depressive Disorder No drug interventions treatment 2 completed NCT03672175
A Study to Evaluate the Efficacy of SAGE-217 in the Treatment of Adult Participants With Major Depressive Disorder treatment 3 completed NCT04007367
A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder treatment 3 terminated NCT04311619
Does rTMS Induce Synaptic Plasticity? other 1 suspended NCT04337242
Blended Care Versus Face-to-Face Therapy for Depression No drug interventions treatment Not Available active_not_recruiting NCT04828226
Clonidine to Prevent Delirium After Electroconvulsive Therapy. prevention 4 recruiting NCT05174273
Neurocognitive Effects of FMT in MDD Patients With and Without IBS other 2 / 3 recruiting NCT05117632
ALTO-100 in MDD and/or PTSD No drug interventions treatment 2 completed NCT05202119
Empower: tDCS for Major Depressive Disorder at Home No drug interventions treatment Not Available completed NCT05259943
Microdosing Psychedelics to Improve Mood treatment 2 recruiting NCT05527509
Risk and Resiliency Factors in the RCMP: A Prospective Investigation No drug interventions prevention Not Available recruiting NCT04751071
The Phosphodiesterase 4 Inhibitor Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder Patients treatment 1 / 2 recruiting NCT04814355
The Effect of Celecoxib on Neuroinflammation in MDD treatment 4 recruiting NCT05347199
Effects of a Single Dose of Amisulpride on Functional Brain Changes treatment 1 completed NCT02615119
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa basic_science Not Available completed NCT03143075
Do Omega-3 Fatty Acids Have an Antidepressant Effect in Patients With Signs of Peripheral Inflammation? No drug interventions treatment Not Available completed NCT03142919
Lipopolysaccharide (LPS) Challenge in Depression No drug interventions basic_science 2 completed NCT04091971
Ketamine Treatment Effects on Synaptic Plasticity in Depression other 4 completed NCT05427981
Anti-suicidal Effects of Buprenorphine In Depressed Individuals treatment 3 withdrawn NCT05558995
Ketogenic Diet Therapy Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT06126198
rTMS Feasibility Study on Adolescent Depression Stimulation No drug interventions treatment Not Available enrolling_by_invitation NCT02461927
Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder treatment 1 / 2 completed NCT02811198
Pain, Reward, Attention and Neurocircuitry: Biomarkers of Suicidality No drug interventions Not Available Not Available recruiting NCT04437485
eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk treatment 2 completed NCT04657575
Optimisation of ECT Based on ASTI vs Narcotrend No drug interventions basic_science Not Available completed NCT05544071
the Safety and Effectiveness of Precise rTMS Based on Neuroimaging in the Treatment of Adolescent Depression With Anhedoniadepression With Anhedonia No drug interventions treatment Not Available recruiting NCT05694156
Musical Attention Control and Executive Function Training for Adults With MDD No drug interventions treatment Not Available recruiting NCT05813093
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression No drug interventions treatment Not Available recruiting NCT06113575
Practical Application of Accelerated iTBS for MDD No drug interventions treatment Not Available completed NCT00071708
Duloxetine Compassionate Use in Patients Who Have Completed a Previous Neuroscience Duloxetine Clinical Trial Not Available Not Available no_longer_available NCT03051074
Examining the Effects of Reduced Environmental Stimulation on Anxiety No drug interventions basic_science Not Available completed NCT03053830
Open Label Ketamine Treatment for Major Depressive Disorder in Veterans treatment 2 completed NCT03538691
A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder treatment 3 completed NCT03665831
Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults No drug interventions treatment Not Available recruiting NCT03748446
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder treatment 0 recruiting NCT03861988
Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery treatment 4 completed NCT03899090
Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression No drug interventions treatment Not Available active_not_recruiting NCT04471818
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer treatment 1 / 2 completed NCT04509102
Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder treatment 0 enrolling_by_invitation NCT04594616
Waitlist-Control Trial of Smartphone CBT for Major Depressive Disorder (MDD) No drug interventions treatment Not Available not_yet_recruiting NCT04633096
The Efficacy of Automated Feedback After Internet-based Depression Screening No drug interventions screening Not Available completed NCT05224206
Neural Mechanisms of Intermittent Theta Burst Stimulation in the Core Depression Network No drug interventions treatment Not Available recruiting NCT05249309
Naturalistic Study of Ketamine in the Treatment of Depression Not Available Not Available active_not_recruiting NCT05583747
E-field Guided iTBS for Treatment Resistant Depression No drug interventions treatment Not Available recruiting NCT05724953
Alexithymia Intervention for Suicide No drug interventions treatment 1 recruiting NCT05775809
Prospective Clinical Cohort Study of Depression Not Available Not Available enrolling_by_invitation NCT05889234
Multimodal Magnetic Resonance Imaging-based Study of Electroconvulsive Efficacy Prediction in Adolescents With Depression: a Multicenter Prospective Cohort Study No drug interventions Not Available Not Available recruiting NCT06026917
Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET) No drug interventions treatment 4 recruiting NCT06043401
Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation Therapy No drug interventions Not Available Not Available recruiting NCT06045897
EEG Microstates Across At-Risk Mental States No drug interventions diagnostic Not Available recruiting NCT06063369
PEA vs. Placebo for Major Depression diagnostic 2 recruiting NCT06070766
RIVER At Home Ketamine Protocols Not Available Not Available recruiting NCT01568307
Major Depressive Disorder - Understanding The Link Between The Brain And The Heart treatment 4 completed NCT04179526
Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems No drug interventions treatment Not Available completed NCT05731323
D-Cycloserine+iTBS PK Study treatment 1 completed NCT05786066
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects basic_science 2 recruiting NCT06025838
Positive Feedback vs. No-Feedback Games for Behavioral Change No drug interventions treatment Not Available not_yet_recruiting NCT06027177
Personalized, Predictive, Precise & Preventive Medicine for Major Depression No drug interventions Not Available Not Available not_yet_recruiting NCT03624933
Effects of Cannabis Abstinence on Symptoms and Cognition in Depression No drug interventions treatment Not Available completed NCT04422652
Combination of Novel Therapies for CKD Comorbid Depression treatment 2 recruiting NCT04826614
Comparing Efficacy of Optimal Treatment and Conventional Treatment for Major Depressive Disorder in Viet Nam No drug interventions treatment Not Available completed NCT04935619
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression No drug interventions treatment Not Available recruiting NCT05840861
Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders Not Available Not Available recruiting NCT05952713
Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder Not Available Not Available completed NCT05976945
Imagery Rescripting as Treatment for Depression No drug interventions treatment Not Available recruiting NCT05988840
Acquisition and Analysis of Relationships Between Longitudinal Emotional Signals Produced by an Artificial Intelligence Algorithm and Self-questionnaires Used in the Psychiatric Follow-up of Patients With Mood and/or Anxiety Disorders: a Real-Environment Study. No drug interventions Not Available Not Available not_yet_recruiting NCT04846829
Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD) No drug interventions treatment 0 active_not_recruiting NCT05061719
An Open-label Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder treatment 3 enrolling_by_invitation NCT05195203
A Study of HS-10353 in Chinese Participants. No drug interventions treatment 1 completed NCT05598034
Evaluating tDCS Brain-stimulation in Depression Using MRI No drug interventions basic_science Not Available recruiting NCT05910957
Multi-Omic, Clinomic and Digitomic Attributes of Major Depression for Integrative Analytics No drug interventions Not Available Not Available enrolling_by_invitation NCT05976659
Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults No drug interventions treatment Not Available recruiting NCT04841798
MAO-B Occupancy in Depressed Patients No drug interventions other Not Available completed NCT04975100
Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Depressive Disorder treatment 4 completed NCT05905120
Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET) No drug interventions treatment 1 completed NCT05957341
pBFS Guided 20min Inter-session Interval rTMS Treatment for MDD No drug interventions treatment Not Available not_yet_recruiting NCT00285935
Cellular Aging and Neurobiology of Depression Study No drug interventions health_services_research Not Available recruiting NCT02369393
Efficacy of Two Internet Delivered Intervention Programs for Depression: Behavioral Activation vs Physical Activity No drug interventions treatment Not Available completed NCT03726658
AGN-241751 in the Treatment of Major Depressive Disorder treatment 1 / 2 completed NCT05842278
The Dosage Effect of pBFS Guided rTMS Treatment for MDD No drug interventions treatment Not Available recruiting NCT05930509
Home-based Non-invasive Brain Stimulation for Treatment-resistant Depression Feasibility, Efficacy and Biomarker of Treatment Response No drug interventions treatment Not Available recruiting NCT05947383
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of up to Two Doses of Psilocybin for the Treatment of Major Depressive Disorder in Adults With Cancer treatment 2 recruiting NCT05950061
Sertraline Versus Escitalopram in South Asian Participants With Moderate to Severe Major Depressive Disorder treatment 3 completed NCT05950711
Ketamine-Assisted Mindfulness-Based Cognitive Therapy for Depression: A Pilot Study No drug interventions treatment 4 recruiting NCT01769859
Systematic Genetic Analysis of Phenomenology and Treatment Response in Mood Disorders No drug interventions Not Available Not Available terminated NCT04629599
IPT for Major Depression Following Perinatal Loss: Healing After Loss (HeAL) No drug interventions treatment 2 / 3 recruiting NCT05913960
Accelerated Intermittent Theta-Burst Stimulation Ameliorate Major Depressive Disorder by Regulating CAMKII Pathway No drug interventions treatment Not Available recruiting NCT02058693
Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy treatment 4 completed NCT02948036
A Closed-loop Assessment and Treatment Platform for Unipolar Depression and Anxiety No drug interventions treatment Not Available completed NCT04120285
Appalachian Mind Health Initiative No drug interventions treatment Not Available recruiting NCT05065580
OMT as an Adjunctive Treatment in MDD No drug interventions treatment Not Available completed NCT03779789
Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment treatment 4 completed NCT05461599
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology No drug interventions treatment Not Available terminated NCT05866042
Boosting Psychotherapy Effects by Means of Transcranial Direct Current Stimulation No drug interventions treatment Not Available completed NCT04838262
Stress and the Sympathetic Nervous System in Adults With Depression No drug interventions basic_science Not Available completed NCT05315401
The Efficacy of Probiotic Compared With Placebo Commitment Therapy for Treatment of Major Depressive Disorder No drug interventions treatment 2 withdrawn NCT05435222
Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders No drug interventions treatment Not Available recruiting NCT05815459
Mobile Observation Of Depression No drug interventions Not Available Not Available completed NCT02507297
Sleep-Disordered Breathing and PAP in Perinatal Depression No drug interventions treatment Not Available completed NCT04004169
Closed-Loop Deep Brain Stimulation for Major Depression No drug interventions treatment Not Available recruiting NCT02176226
IntelliCare: Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM) No drug interventions treatment Not Available completed NCT03068247
Neurobiology of Treatment Responses in MDD other 3 withdrawn NCT03222752
Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder No drug interventions treatment Not Available terminated NCT03889756
Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy treatment 2 / 3 terminated NCT05832619
Intradermal Acupuncture Versus Sham Acupuncture and SSRI for Treating Adolescents With Major Depressive Disorder treatment Not Available recruiting NCT02209142
Blood Biomarkers in Major Depression No drug interventions diagnostic Not Available completed NCT05816018
Improving Health Care in Major Depressive Disorder No drug interventions Not Available Not Available recruiting NCT03307070
Adapted Cognitive Behavioral Treatment for Depression in Patients With Moderate to Severe Traumatic Brain Injury No drug interventions treatment Not Available completed NCT05597241
Multiple Ascending Dose and Electroencephalography Trial of GATE-202 in Healthy Volunteers No drug interventions treatment 1 completed NCT03523767
Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study No drug interventions basic_science 1 terminated NCT01990053
Pilot Study Assessing Computerized Cognitive Behavioral Therapy for Depression No drug interventions treatment Not Available completed NCT03866252
LSD Therapy for Persons Suffering From Major Depression treatment 2 completed NCT04285515
Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder treatment 3 completed NCT04748276
Tracking Response to Antidepressants in Advance of Investigational Trials Not Available Not Available recruiting NCT04850911
Reward Emotion Learning and Ketamine Study basic_science Not Available recruiting NCT04939818
Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders No drug interventions Not Available Not Available completed NCT05682183
Multi-domain Psychoeducation Self-management Program for Adults With MDD in Singapore No drug interventions health_services_research Not Available recruiting NCT05778643
TaKeTiNa in the Treatment of Depression: a Pilot Study. No drug interventions treatment Not Available recruiting NCT05785312
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan No drug interventions treatment Not Available not_yet_recruiting NCT03302611
Trial of Surf and Hike Therapy for Major Depressive Disorder No drug interventions treatment Not Available completed NCT03977038
Investigation of the Effects of Repetitive Transcranial Magnetic Stimulation on Cognition in Depression No drug interventions Not Available Not Available completed NCT04891224
Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression No drug interventions health_services_research Not Available completed NCT05767593
Clinical Validation of Samsung Smartwatch No drug interventions Not Available Not Available recruiting NCT04634669
Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE) treatment 2 completed NCT05366270
Peripheral Neuroimmune Mechanisms of Hyperthermia No drug interventions basic_science Not Available recruiting NCT04162522
Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study diagnostic 3 completed NCT05138653
A Single and Multiple Ascending Dose Trial of CVL-354 in Healthy Participants No drug interventions treatment 1 completed NCT05273983
Pilot Study of a Brief Behavioural Activation Intervention for Depressed Patients in Primary Care No drug interventions treatment Not Available terminated NCT01742832
Double-Blind Treatment of Major Depressive Disorder With Vilazodone treatment 2 completed NCT03378570
rTMS for MDD: 5.5cm Rule vs. F3 Targeting No drug interventions treatment Not Available completed NCT02129751
Efficacy and Safety of Bupropion Hydrobromide in Adolescents and Children With Major Depressive Disorder treatment 4 not_yet_recruiting NCT02188121
Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients treatment 4 completed NCT03026036
Neuroimaging Studies of Reward Processing in Depression No drug interventions Not Available Not Available completed NCT05024149
Assessing the Impact of Electroacupuncture on Facial Thermal Characteristics of Major Depressive Disorder Patients Based on Infrared Thermal Imaging Technology No drug interventions diagnostic Not Available enrolling_by_invitation NCT05144880
Effects of Electroacupuncture With Different Frequencies for Major Depressive Disorder No drug interventions treatment Not Available active_not_recruiting NCT05601648
PET Synaptogenesis After Psilocybin In DEpression Recovery treatment 2 withdrawn NCT05707299
The Effect of Intradermal Acupuncture on Gallbladder Meridian Points on Cerebral Hemodynamics in Relevant Brain Regions for Major Depressive Disorder Based on fNIRS Technology No drug interventions basic_science Not Available not_yet_recruiting NCT03079297
Rapid Antidepressant Effects of Leucine treatment 2 terminated NCT05450432
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression treatment 4 recruiting NCT05694754
Transcranial Magnetic Stimulation Theta Burst (TMS), Depression and Smoking. No drug interventions treatment Not Available recruiting NCT03998748
Electrophysiological Correlates of Cognition in Depression No drug interventions basic_science Not Available terminated NCT04344678
The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients treatment Not Available recruiting NCT03869736
Nitrous Oxide for the Treatment of Major Depressive Disorder treatment 2 recruiting NCT02476058
A Safety, Efficacy and Biomarker Study of JNJ-42847922 in Participants With Major Depressive Disorder treatment 1 completed NCT04342299
The Antidepressant Advisor (Study 3): fMRI Study to Predict Treatment Response in Patients With Depression No drug interventions Not Available Not Available completed NCT05644301
INflammation-based Stratification for Immune-Targeted Augmentation in Major Depressive Disorder treatment 3 not_yet_recruiting NCT05643898
"Mamá, te Entiendo" App-based Intervention for Reducing Depressive Symptoms in Postpartum Women No drug interventions treatment Not Available not_yet_recruiting NCT05605002
Efficacy and Safety of Intradermal Acupuncture for Major Depressive Disorder treatment Not Available recruiting NCT05585047
Treatment Response Biomarkers in MDD No drug interventions Not Available Not Available recruiting NCT05575713
The Effect of Soluble Epoxide Hydrolase (SEH) on Depression No drug interventions Not Available Not Available recruiting NCT05568823
Biomarkers of ANTidepressant RESponse and Development Risk of Bipolar Disorder No drug interventions treatment Not Available not_yet_recruiting NCT05565352
Observation of Ketamine Treatment Safety and Tolerability in Adult Psychiatry Clinic Medical University of Gdańsk Inpatients Not Available Not Available enrolling_by_invitation NCT05547711
Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting No drug interventions other Not Available not_yet_recruiting NCT05543421
Transcranial Magnetic Stimulation in Patients With a Depressive Episode - RCT Trial No drug interventions treatment Not Available recruiting NCT05539495
Exercise Recovery From Persistent Depression: A Thematic Analysis No drug interventions Not Available Not Available not_yet_recruiting NCT05529576
Multi-factor Model Constraction for Early Warning and Diagnosis of MDD treatment 4 recruiting NCT05527951
Enhanced Measurement-Based Care Effectiveness for Depression (EMBED) Study No drug interventions other Not Available recruiting NCT05506462
An EEG Study of Intravenous Ketamine for Major Depression Disorder treatment 4 not_yet_recruiting NCT05499117
Efficacy and Safety of Light Therapy in the Treatment of Non-seasonal Depressive Disorder in Chinese Population No drug interventions treatment Not Available recruiting NCT05465915
Pulse Width 0.15ms vs 0.30ms in Electroconvulsive Therapy No drug interventions treatment 0 recruiting NCT05422417
Dorsomedial Prefrontal Neuromodulation in Treatment-resistant Depression No drug interventions treatment Not Available recruiting NCT05400785
Efficacy of the Mobile Application for Prediction and Prevention of Mood Episode Recurrence Based on Machine Learning No drug interventions prevention Not Available recruiting NCT05355285
Type 1 Diabetes and Depression: Role of Brain Glutamate No drug interventions basic_science Not Available completed NCT05352113
Intradermal Needle Therapy for Major Depressive Disorder No drug interventions treatment Not Available not_yet_recruiting NCT05318924
Effects of Ghrelin Administration on Dopamine and Effort basic_science 1 / 2 recruiting NCT05295888
Temporal Interference and Depression No drug interventions treatment Not Available not_yet_recruiting NCT05260086
Pre-mapping Networks for Brain Stimulation 2 No drug interventions treatment Not Available completed NCT05236959
Mindfulness-Based Cognitive Therapy for Depressed IAPT Non-Responders No drug interventions treatment Not Available recruiting NCT05217758
RESET-medication Glucocorticoid Receptor (GR) Blockade as Disease Modifying Treatment for Depression With Childhood Trauma treatment 2 recruiting NCT05212389
The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling No drug interventions basic_science Not Available recruiting NCT05205915
Home-based Transcranial Direct Current Stimulation (tDCS) for Major Depressive Disorders (MDD) No drug interventions device_feasibility Not Available active_not_recruiting NCT05149352
RESET-psychotherapy: the Effectiveness of Trauma-focused Therapy in Patients With Depression and Childhood Trauma No drug interventions treatment Not Available recruiting NCT05145270
A Comparative Study on Efficacy and Safety of add-on Sulforaphane or rTMS to Escitalopram for Major Depressive Disorder With Poor Response to Initial Treatment treatment 4 recruiting NCT05137197
Confirm the Effectiveness of Predictix Genetics Antidepressant -Guided Treatment in Adults With MDD No drug interventions supportive_care Not Available recruiting NCT05135897
The Neurobiological Fundaments of Depression and Its Relief Through Neurostimulation Treatments No drug interventions Not Available Not Available recruiting NCT05120336
tVNS Effects on Motivation in Depression No drug interventions basic_science Not Available completed NCT05118594
Testing a Precision Psychotherapy System for Low-income Patients No drug interventions treatment Not Available not_yet_recruiting NCT05104918
Vortioxetine as a Novel Anti-depressant With Improvement in Cognitive Abilities treatment 3 not_yet_recruiting NCT05054699
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study No drug interventions treatment 2 / 3 recruiting NCT05045378
Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression treatment 4 recruiting NCT05028738
Patient-oriented Randomized Pragmatic Feasibility Trial With rTMS in Depression and Anxiety No drug interventions treatment Not Available recruiting NCT04999553
Left vs. Right Non-Inferiority Trial No drug interventions treatment Not Available recruiting NCT04986124
Quality of Life in Chinese Working and School Age Population With MDD No drug interventions Not Available Not Available recruiting NCT04981561
Safety and Tolerability of GATE-251 in Normal Human Volunteers treatment 1 completed NCT04971291
An Evaluation of AXS-05 for the Treatment of TRD in Treatment-Adherent Patients treatment 2 enrolling_by_invitation NCT04924257
ECT vs. Esketamine treatment 3 withdrawn NCT04887350
SSIPP vs. PST vs. WLC No drug interventions treatment 1 withdrawn NCT04874077
Using Voice Biomarkers to Predict the Likelihood of Major Depressive Disorder No drug interventions Not Available Not Available completed NCT04847245
Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder treatment Not Available not_yet_recruiting NCT04842929
Magnetic Randomized Trial in Elderly Depressed No drug interventions treatment Not Available recruiting NCT04843462
Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray treatment Not Available recruiting NCT04824157
Ketamine IV Classic Protocol : Five Years Follow up No drug interventions Not Available Not Available completed NCT04799405
Home-based tDCS in Major Depressive Disorder No drug interventions treatment Not Available completed NCT04788524
Neural Correlates of Stress and Perceived Control in Adolescent Depression No drug interventions basic_science Not Available recruiting NCT04780152
TDCS in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemic treatment 2 / 3 recruiting NCT04768361
Behavioral Activation for Major Depression With and Without Mindfulness No drug interventions treatment Not Available completed NCT04731454
Feasibility and Acceptability of a Healthy Nordic Diet Intervention in Depressed and Non-depressed Adults No drug interventions other Not Available completed NCT04697693
Antidepressant Response in Older Adults With Comorbid PTSD and MDD treatment 4 terminated NCT04679753
Brainsway DTMS for Treatment of MDD Using iTBS No drug interventions treatment 4 completed NCT04623034
Evaluation of the Safety and Pharmacokinetics of MSI-195 to a Commercial S-Adenosylmethionine other 1 completed NCT04618263
Safety and Tolerability of Single and Multiple Ascending Doses of GATE-101 in Normal Human Volunteers No drug interventions treatment 1 terminated NCT04615234
Clinical Validation of a Combinatorial Pharmacogenomic Approach in Major Depressive Disorder No drug interventions Not Available Not Available recruiting NCT04608396
Mechanistic Evaluation of Response in TRD (MERIT) No drug interventions treatment 2 completed NCT04609267
Interactive Voice-Based Administration of the PHQ-9 No drug interventions diagnostic Not Available recruiting NCT04602715
The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression No drug interventions treatment 2 recruiting NCT04598607
Tolerability and Pharmacokinetics of Hypidone Hydrochloride in Healthy Subjects No drug interventions treatment 1 completed NCT04593537
Action Tendencies and Prognosis in Major Depressive Disorder No drug interventions Not Available Not Available completed NCT04543123
Effect of Self-administered tDCS in Patients With MDD treatment 4 completed NCT04541563
Fisher Wallace Neurostimulation & Depression Study No drug interventions treatment Not Available active_not_recruiting NCT04536714
Efficacy of Pythagorean Self-Awareness Intervention for Major Depressive Disorder No drug interventions treatment Not Available completed NCT04528628
Optimization of Diagnosis and Treatment of Depression Based on Multidimensional Clinical Assessment Classification treatment Not Available unknown_status NCT04510519
Scaling Mental Healthcare in COVID-19 With Voice Biomarkers No drug interventions Not Available Not Available completed NCT04469608
Establishing TCM Daycare Model and Teaching Mechanism of Depression Patients No drug interventions treatment Not Available unknown_status NCT04467164
Vagus Nerve Stimulation: Integration of Behavior and Cardiac Modulation No drug interventions basic_science Not Available completed NCT04447430
Light Therapy to Improve Symptoms in Pregnant Women With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT04430556
Brain Hippocampal Volume Relationship With Anxious Symptoms in Major Depressive Patients health_services_research Not Available unknown_status NCT04425278
tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT04423471
Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis No drug interventions Not Available Not Available withdrawn NCT04399070
The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) treatment Not Available unknown_status NCT04364997
Study of Desvenlafaxine in Treating Major Depressive Disorder. treatment 3 completed NCT04355650
Augmented Human Intelligence in Major Depressive Disorder No drug interventions other Not Available completed NCT04353921
PSIL201 Long-term Follow-up Study: Psilocybin or Niacin / Major Depressive Disorder No drug interventions Not Available Not Available terminated NCT04347577
Intestinal Flora and Major Depressive Disorders Not Available Not Available recruiting NCT04325100
Intervention Targeting Motivational Negative Symptoms No drug interventions treatment Not Available completed NCT04295941
Long-term Study With Trazodone Once-a-Day Not Available Not Available completed NCT04294654
Vortioxetine in Patients With Depression and Early Dementia treatment 4 completed NCT04268316
Virtual Reality Behavioral Activation: An Intervention for Major Depressive Disorder No drug interventions treatment Not Available completed NCT04253678
Vortioxetine for Cancer Patients With Depression: An Observational Study Not Available Not Available unknown_status NCT04244253
A Phase 2 Trial of OPC-64005 for Major Depressive Disorder No drug interventions treatment 2 completed NCT04217837
Treatment of Major Depressive Disorder in the UK Using TMS Therapy No drug interventions Not Available Not Available withdrawn NCT04208932
A Kynurenine Pathway-based Molecular Imaging Study of Individualized Diagnosis and Treatment for Major Depressive Disorder No drug interventions Not Available Not Available unknown_status NCT04206969
Assessment of Transcultural Psychotherapy in Child Major Depressive Disorder No drug interventions supportive_care Not Available not_yet_recruiting NCT04199845
8-week of PS128 RCT in Patients With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT04181736
The BIomarker Guided Study for Depression treatment 4 recruiting NCT04159207
A Longitudinal Study of Inflammatory Pathways in Depression No drug interventions Not Available Not Available recruiting NCT04156425
The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression treatment Not Available not_yet_recruiting NCT04138290
Post Marketing Study for the Evaluation of Predictix Antidepressant Clinician Software Support Tool in Prescribing Antidepressant Medication/s for the Treatment of Patients Suffering From Major Depressive Disorder No drug interventions supportive_care 4 unknown_status NCT04137367
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination No drug interventions treatment Not Available completed NCT04124276
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in Patients With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT04114565
Prevalence of Major Depression Among Immigrants in Santiago, Chile No drug interventions Not Available Not Available completed NCT04104698
Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients No drug interventions Not Available Not Available unknown_status NCT04082806
Memory Enhancement by Gamma-hydroxybutyrate vs. Trazodone in Major Depressive Disorder. treatment 2 completed NCT04069819
The Phosphodiesterase-3 Inhibitor Cilostazol as an Adjunctive to Antidepressants in Patients With Major Depressive Disorder. treatment Not Available completed NCT04068467
Evaluation of mHealth for Serious Mental Illness No drug interventions supportive_care Not Available completed NCT04055181
Influence of rTMS on Symptoms and Cognitive Function in Patients With Psychiatric Disorders No drug interventions treatment Not Available completed NCT04039022
Open-Label Safety Study of AXS-05 in Subjects With Depression treatment 3 completed NCT04037111
Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms No drug interventions basic_science Not Available unknown_status NCT04031937
Sensory and Psychomotor Profile in Depression No drug interventions screening Not Available completed NCT04032015
rTMS Study in Depression to Evaluate the Relationship Between Brain Plasticity and Clinical Outcome No drug interventions basic_science Not Available withdrawn NCT04031157
Controlled Study to Evaluate the Safety and Efficacy of the Predictix Antidepressant Clinician Support Tool No drug interventions supportive_care Not Available unknown_status NCT04019704
A Trial of AXS-05 in Patients With Major Depressive Disorder No drug interventions treatment 3 completed NCT04009135
The Internet Therapy for Depression Trial No drug interventions treatment Not Available completed NCT04006834
Hypersomnia in Major Depressive Disorder No drug interventions Not Available Not Available unknown_status NCT04000022
Repetitive Transcranial Magnetic Stimulation in Pharmaco-naĂŻve Patients With Major Depression No drug interventions Not Available Not Available recruiting NCT03999736
Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression No drug interventions treatment 1 / 2 terminated NCT03977675
The Role of HNKs in the Antidepressant Effect of Ketamine basic_science 1 terminated NCT03959735
High Intensity Interval Training in Severe Mental Illness No drug interventions treatment Not Available completed NCT03937596
Adjunctive D-Cycloserine in Major Depressive Disorder treatment 2 completed NCT03925168
Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes No drug interventions treatment Not Available completed NCT03899285
Citalopram Titration in Early Non-responder Patients With Major Depressive Disorders treatment 2 completed NCT03881449
DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole treatment 4 unknown_status NCT03871088
N-3 Fatty Acids as the First-line Antidepressant Therapy: From Biomarkers to Clinical Subtypes No drug interventions basic_science Not Available completed NCT03842345
DELPhI Evaluation of Psychiatric Conditions No drug interventions Not Available Not Available withdrawn NCT03835715
Study With Vortioxetine on Emotional Functioning in Patients With Depression treatment 4 completed NCT03833063
Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression treatment 1 withdrawn NCT03822065
A Relative Bioavailability Food Effect Study of LY03005 treatment 1 completed NCT03822416
Treating Smokers With Mental Illness treatment 2 completed NCT03812588
Contact: Developing New Clinical Management Strategies treatment 4 completed NCT03795688
The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health No drug interventions Not Available Not Available completed NCT03790085
Identification of Multi-modal Bio-markers for Early Diagnosis and Treatment Prediction in Schizophrenia Individuals diagnostic 0 unknown_status NCT03786731
A Transdiagnostic Sleep and Circadian Treatment for Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT03785652
Dose-Finding Clinical Trial to Evaluate the Efficacy and Safety of LY03005 Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD) treatment 1 completed NCT03739632
Study to Explore the Effective Doses and to Assess the Safety and Efficacy of Hypidone Hydrochloride Tablets No drug interventions treatment 2 completed NCT03739203
The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone treatment 3 completed NCT03738215
Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone treatment 3 completed NCT03735576
Cognitive Behavioural Therapy for the Treatment of Late Life Depression No drug interventions treatment Not Available completed NCT03733574
A Study of LY03005 vs Pristiq treatment 1 completed NCT03731728
Group CBT and Exercise in Management of Depression No drug interventions treatment Not Available terminated NCT03721900
Ketamine for Major Depressive Disorder treatment 1 unknown_status NCT03718013
Efficacy and Safety of Accelerated Transcranial Magnetic Stimulation With H1-coil (dTMS) No drug interventions treatment Not Available completed NCT03711045
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk No drug interventions Not Available Not Available unknown_status NCT03703414
Characterization of Microbial, Immune and Epigenetic Biomarkers for Major Depressive Disorder and ECT Treatment No drug interventions Not Available Not Available unknown_status NCT03652597
Neuro-Cardiac-Guided Transcranial Magnetic Stimulation: Replication and Dose-response. No drug interventions basic_science Not Available completed NCT03643159
A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder health_services_research 4 terminated NCT03628027
The Antidepressant Advisor Study No drug interventions other 2 unknown_status NCT03623711
A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression treatment 0 recruiting NCT03620253
Modafinil's Effects on Cognition in Remitted MDD treatment 3 terminated NCT03609190
A Multimodal Neuroimaging Study of Brain Activation Patterns Under Ketamine basic_science 0 completed NCT03606850
Transcranial Magnetic Stimulation Study of Cortical Excitability as Marker of Antidepressant Response: EXCIPSY Study No drug interventions treatment Not Available unknown_status NCT03591224
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy No drug interventions treatment Not Available completed NCT03569475
Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive Disorder treatment 3 completed NCT03558256
The Study of Mindfulness-based Cognitive Therapy and Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT03556124
Transcranial Direct Current Stimulation in Major Depression No drug interventions treatment Not Available completed NCT03555136
Real-life Effectiveness of Vortioxetine in Depression Not Available Not Available completed NCT03554447
Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder treatment Not Available completed NCT03551288
Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-911 in Healthy Subjects No drug interventions treatment 1 completed NCT03548545
tDCS as add-on Treatment to Cognitive-Behavior Therapy in People With MDD No drug interventions treatment Not Available unknown_status NCT03537547
Combinatorial Pharmacogenomics Testing in Treatment-NaĂŻve Major Depressive Disorder No drug interventions treatment 4 terminated NCT03511599
Cycloserine rTMS Plasticity Augmentation in Depression basic_science 1 completed NCT03504475
Bioequivalence Study of Paroxetine Tablets and Paxil® Under Fasting and Fed Conditions in Chinese Healthy Volunteers prevention 1 completed NCT03487198
The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder treatment 3 terminated NCT03460574
Targeting Cognitive Immunization in Depression No drug interventions treatment Not Available completed NCT03446846
A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive Disorder No drug interventions treatment 2 completed NCT03435744
Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial. treatment 3 completed NCT03432221
Switching From SSRI to Desvenlafaxine on Cognitive Functioning Not Available Not Available unknown_status NCT03430869
Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK) diagnostic 2 completed NCT03429361
Testing the Value of Smartphone Assessments of People With Mood Disorders No drug interventions Not Available Not Available completed NCT03414619
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts" No drug interventions diagnostic Not Available completed NCT03388177
Yoga for Young Women With Depression No drug interventions treatment Not Available unknown_status NCT03329287
Simplified Cognitive Behavioral Therapy for Generalized Anxiety Disorder and Depression No drug interventions treatment Not Available unknown_status NCT03313674
Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD No drug interventions diagnostic Not Available completed NCT03310281
Software Treatments for Actively Reducing Severity of Cognitive Deficits in MDD (STARS-MDD) No drug interventions treatment Not Available completed NCT03265340
Clinical Effect of dTMS in Major Depressive Disorder No drug interventions treatment Not Available completed NCT03254342
MRS and Medication Response: A Pilot Study No drug interventions Not Available Not Available terminated NCT03242213
Patient Management of Depression Through Technology: a Study of Digitally Enabled Engagement No drug interventions supportive_care Not Available completed NCT03237078
Lactobacillus Plantarum PS128 in Patients With Major Depressive Disorder and High Level of Inflammation No drug interventions treatment Not Available unknown_status NCT03230682
Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder Not Available Not Available unknown_status NCT03228953
Pharmacogenomic Testing in Major Depressive Disorder No drug interventions health_services_research Not Available terminated NCT03203954
Testing the Neuroscience of Guided Learning in Depression No drug interventions other Not Available completed NCT03193398
BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder treatment 2 completed NCT03191994
Impact of an Eight Week Exercise Intervention in Treating Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT03188185
A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD) No drug interventions treatment 3 completed NCT03187093
Cognitive Dysfunction in MDD Patients treatment 4 unknown_status NCT03183505
Comparison of Anyu Peibo With Placebo in Treatment of MDD，Ⅱb No drug interventions treatment 2 completed NCT03181529
Effects of Psilocybin in Major Depressive Disorder treatment 2 completed NCT03156556
Improving Access to the Treatment of Anxiety and Depression Among Young Adults No drug interventions treatment Not Available completed NCT03143634
The Modular Protocol for Mental Health (MPMH) No drug interventions treatment 1 / 2 completed NCT03121573
Efficacy and Safety of Duloxetine Among Individuals With Depressive Disorder in a 12 Weeks Trial health_services_research Not Available completed NCT03088657
Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study No drug interventions Not Available Not Available unknown_status NCT03084042
Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety No drug interventions Not Available Not Available unknown_status NCT03078322
AV-101 as Adjunct Antidepressant Therapy in Patients With Major Depression treatment 2 completed NCT03067506
Cognitive and Mood Assessment Data in Major Depressive Disorder Using Digital Wearable Technology No drug interventions Not Available Not Available completed NCT03062332
The Gut Microbiota of Bipolar and Depression No drug interventions Not Available Not Available recruiting NCT03053362
THINC-it Vortioxetine - Sensitivity to Change other 2 / 3 completed NCT03051945
Endogenous Opioid Modulation by Ketamine basic_science 3 withdrawn NCT03009448
The Experience of Older Adults Facing Depression for the First Time in Old Age No drug interventions Not Available Not Available unknown_status NCT02998762
Long-Term Follow Up Study No drug interventions Not Available Not Available completed NCT02983838
Research on Pathophysiology and Treatment in Depression Using Brain Derived Neurotrophic Factor and Amyloid Neuroimaging No drug interventions Not Available Not Available unknown_status NCT02972632
Goal Achievement After a Change to Vortioxetine in Adults With Major Depressive Disorder treatment 4 completed NCT02959307
Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3) No drug interventions treatment Not Available completed NCT02943096
Flavanol Augmentation for Antidepressant Non-Responsive Late Life Depression No drug interventions treatment Not Available terminated NCT02940769
Neurobiological Effects of Light on MDD No drug interventions basic_science Not Available terminated NCT02939560
TMS for Adults With Autism and Depression No drug interventions treatment Not Available completed NCT02935647
Burst Suppression Anesthesia for Treatment of Severe Depression treatment 1 completed NCT02934334
Wellness Monitoring for Major Depressive Disorder No drug interventions Not Available Not Available completed NCT02922556
Piloting a Novel, Mobile Cognitive Training Tool for Patients With Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT02900092
Augmentation of Treatment-Resistant Depression With An Analog of the Neuroactive Steroid Allopregnanolone treatment Not Available completed NCT02882711
The UTHealth Ketamine Project treatment 2 terminated NCT02871141
Multimodal Imaging of ECT Effects No drug interventions Not Available Not Available completed NCT02869035
Treatment Outcome in Major Depressive Disorder other 1 completed NCT02860910
Cognitive Behavioral Group Therapy for the Management of Menopause Symptoms in Mood Disorders No drug interventions treatment Not Available completed NCT02855580
Integrating Pharmacogenomic Testing Into a Child Psychiatry Clinic No drug interventions Not Available Not Available completed NCT02843373
Brain-Based Biomarkers in Response to TMS in MDD No drug interventions Not Available Not Available completed NCT02837887
Computerized Cognitive Behavior Therapy in Treating Depression in Patients With Cancer No drug interventions supportive_care Not Available completed NCT02830399
Clinical Trial on Efficacy of rTMS to Improve ECT in Treatment-Resistant Depression No drug interventions treatment Not Available completed NCT02815813
Lifestyle Intervention for Young Adults With Serious Mental Illness No drug interventions treatment Not Available completed NCT02816138
Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study) treatment 4 completed NCT02809677
Treating Caregiver Depression to Improve Childhood Asthma: Impact and Mediators No drug interventions diagnostic Not Available completed NCT02805881
Safety and Feasibility of Combined Trigeminal and Occipital Transcutaneous Nerve Stimulation (CTO-TNS) in Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT02805439
Efficacy and Safety of S 47445 Versus Placebo as Adjunctive Treatment in Depressed Patients Not Fully Recovered From Depressive Symptoms With a Current Antidepressant Treatment treatment 2 completed NCT02802293
Treatment of Depression With Connectivity Guided Robotically Delivered rTMS No drug interventions treatment Not Available terminated NCT02801513
Maintaining Mechanisms of Chronic Depression and Their Changeability No drug interventions basic_science Not Available completed NCT02800226
Pilot Study Comparing 10hz vs Theta Burst Stimulation No drug interventions treatment 3 completed NCT02793258
Impact of tDCS on Emotional Processing in Major Depression No drug interventions treatment Not Available completed NCT02752724
Ketamine Anesthesia for Improvement of Depression in ECT treatment Not Available completed NCT02749721
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder other 4 completed NCT02747134
Combining Emotion Regulation and Mindfulness Skills for Preventing Depression Relapse No drug interventions treatment Not Available completed NCT02720198
Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDD treatment 3 completed NCT02715778
Translational Investigation of Gestational Environment on Neurobehavioral Function in Children No drug interventions Not Available Not Available completed NCT02715128
Disorder-tailored Transcranial Direct Current Stimulation (tDCS) of the Prefrontal Cortex No drug interventions basic_science Not Available unknown_status NCT02711215
Patient Stratification and Treatment Response Prediction in Neuropharmacotherapy Using Hybrid Positron Emmission Tomography/Magnetic Resconance Imaging (PET/MR) basic_science 4 unknown_status NCT02709161
Effects of Amygdala Neurofeedback on Depressive Symptoms No drug interventions treatment Not Available completed NCT02685982
Treating Major Depressive Disorder With Music and Low-frequency Rhythmic Sensory Stimulation No drug interventions treatment Not Available completed NCT02666989
Open-Label Placebo for the Treatment of Depression No drug interventions treatment Not Available unknown_status NCT02661828
Tapering Off Antidepressants No drug interventions treatment Not Available terminated NCT02660528
Tocilizumab Augmentation in Treatment-Refractory Major Depressive Disorder treatment 2 terminated NCT02661061
Ketamine for Relapse Prevention in Recurrent Depressive Disorder other 1 terminated NCT02657980
The Effect of tDCS in Patients With Moderate to Severe Major Depressive Disorder No drug interventions treatment 3 completed NCT02646449
Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial treatment 2 completed NCT02634177
Genecept Assay™ vs. Treatment-as-Usual to Evaluate Efficacy of Assay-Guided Treatment in Adults With MDD No drug interventions treatment Not Available completed NCT02624102
Efficacy of Trial-Based Cognitive Therapy and Behavioral Activation in Treatment of Depression No drug interventions treatment 3 completed NCT02615405
Phospholipid Hypothesis of Depression: From Molecular Biology, Neuroimaging to Behaviour No drug interventions treatment Not Available completed NCT02616549
Multicomponent Yoga Intervention for Major Depressive Disorder No drug interventions treatment 2 completed NCT02614326
MemFlex to Prevent Depressive Relapse No drug interventions prevention 2 completed NCT02612142
Physical EXercise as an Adjunct Treatment for Depression No drug interventions treatment Not Available completed NCT02593643
Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression. treatment 0 completed NCT02586688
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents No drug interventions treatment Not Available unknown_status NCT02579928
Ketamine Infusion for Adolescent Depression and Anxiety treatment 4 completed NCT02568865
Noninvasive Physiologic Sensors to Assess Depression No drug interventions Not Available Not Available completed NCT02562677
TNS for Treating Major Depressive Disorder in the Elderly No drug interventions treatment 1 / 2 unknown_status NCT02553915
Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized Approach treatment 2 / 3 completed NCT02549547
Jump Step - A Participatory Approach to Physical Activity & Mental Wellness No drug interventions treatment Not Available unknown_status NCT02548949
Korean Post Marketing Surveillance to Observe Effectiveness and Safety of PRISTIQ No drug interventions Not Available Not Available completed NCT02544607
Ketamine for Depression: An MRI Study other 4 completed NCT02525978
Heart Rate Variability in Depression No drug interventions other Not Available completed NCT02522377
Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression treatment Not Available completed NCT02508493
Validation of the THINC-it Tool for Cognitive Dysfunction in Major Depressive Disorder No drug interventions Not Available Not Available completed NCT02507219
Study of Ibuprofen Effects on Brain Function basic_science 2 / 3 completed NCT02479464
Clinical Impact of the Antidepressant Pharmacogenomic Algorithm in an Outpatient Therapy-based Clinical Setting No drug interventions other Not Available completed NCT02480400
The Effect of Patient and Investigator Expectation on the Efficacy of Escitalopram in the Treatment Depression health_services_research Not Available completed NCT02473783
The Serotonin Transporter Availability for Prognosing Major Depressive Disorder (MDD) Treatment and Detecting MDD other 2 completed NCT02470026
Noradrenergic Activity, Cognition and Major Depressive Disorder basic_science Not Available completed NCT02459236
A Study of Intermittent Doses of CERC-301 in MDD treatment 2 completed NCT02456948
Adjunct Minocyline in Treatment-resistant Depression treatment 2 completed NCT02443584
Pharmacogenetic Testing on an Outpatient Population With a Depression Diagnosis No drug interventions supportive_care Not Available completed NCT02440815
Multimodal MRI Characteristics of Psychotherapy Response in Late Life Depression No drug interventions basic_science Not Available completed NCT02431806
Safety and Efficacy of Levomilnacipran ER in Adolescent Participants With Major Depressive Disorder treatment 3 completed NCT02429011
MRI Studies of Emotion in Depression No drug interventions Not Available Not Available completed NCT02423824
Cognitive Dysfunction and Glucagon-like Peptide-1 Agonists treatment 3 completed NCT02422303
Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms treatment Not Available terminated NCT02415166
Influenza Challenge in Mood Disorders No drug interventions basic_science Not Available terminated NCT02409823
Clinical Registry of Patients Under Treatment With Atypical Antipsychotics No drug interventions Not Available Not Available completed NCT02400736
Supported Employment in Patient Aligned Care Teams No drug interventions treatment Not Available completed NCT02398877
HPA Axis Activity Due To Early Traumatic Stress and Metabolic Symptoms No drug interventions basic_science Not Available completed NCT02395978
A Phase II Study of PDC-1421 Capsule to Evaluate the Safety and Efficacy in Patients With Major Depressive Disorder No drug interventions treatment 2 completed NCT02389816
A Phase 3 Study of Lu AA21004 in Patients With Major Depressive Disorder treatment 3 completed NCT02383693
Maintenance rTMS for Treatment-resistant Depression (TRD): a One-year Double Blind Controlled Study No drug interventions treatment 2 / 3 unknown_status NCT02378714
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers treatment 4 completed NCT02376257
Improving Therapeutic Learning in Depression: Proof of Concept treatment 2 completed NCT02375308
Efficacy of Cognitive Behavioral to Hypnotherapeutic Treatment of Depression No drug interventions treatment Not Available completed NCT02372799
Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22) treatment 3 completed NCT02366364
Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers treatment 1 completed NCT02362529
Biomarkers of Neuroinflammation and Anti-Inflammatory Treatments in Major Depressive Disorder basic_science 0 completed NCT02356107
5-hydroxytryptophan and Creatine for Treatment Resistant Depression Associated With Hypoxia in Females treatment 4 completed NCT02348827
Family Psychoeducation for Major Depressive Disorder No drug interventions prevention Not Available unknown_status NCT02339285
Transcranial Alternating Current Stimulation for Major Depressive Disorder No drug interventions treatment Not Available completed NCT02334228
Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness No drug interventions prevention Not Available completed NCT02332954
Assessment in Work Productivity and the Relationship With Cognitive Symptoms in Patients With MDD Taking Vortioxetine treatment 4 completed NCT02330679
Prediction of Antidepressant Treatment Response Using Machine Learning Classification Analysis treatment 4 unknown_status NCT02330744
The Neurobiology of Approach Avoidance Training in Depression No drug interventions treatment Not Available completed NCT02308956
Task Sharing for the Care of Severe Mental Disorders in a Low-income Country No drug interventions health_services_research 3 completed NCT02307617
Glutamate Probes in Adolescent Depression No drug interventions Not Available Not Available completed NCT02294305
Vortioxetine Versus Placebo in Major Depressive Disorder Comorbid With Social Anxiety Disorder treatment 4 unknown_status NCT02285608
Partnership in Medication Management (PIMM) in Patients With Mood Disorders No drug interventions health_services_research Not Available unknown_status NCT02283541
Gait, Depression, and Mind-body Therapy in Seniors No drug interventions treatment Not Available completed NCT02279953
Efficacy of Vortioxetine on Cognitive Dysfunction in Patients With Partial or Full Remission of Major Depressive Disorder treatment 3 completed NCT02272517
Efficacy of Vortioxetine Versus Escitalopram on Cognitive Function in Patients With Inadequate Response to Current Antidepressant Treatment of Major Depressive Disorder treatment 3 completed NCT02269540
A New Treatment Approach for Major Depressive Disorder Based Upon Targeting Monoamine Oxidase A (MAO-A) treatment 0 completed NCT02268487
Integral Assessment in Unipolar Depression treatment 4 unknown_status NCT02266693
Transdiagnostic iCBT for Depression and Anxiety No drug interventions treatment Not Available completed NCT02263248
Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine treatment 1 / 2 completed NCT02256566
Cognitive Training for Mood and Anxiety Disorders No drug interventions treatment Not Available completed NCT02238730
Ultrabrief Right Unilateral and Brief Pulse Bitemporal Electroconvulsive Therapy No drug interventions treatment Not Available withdrawn NCT02236702
Kappa Opioid Receptor Imaging in Depression (KOR Depression) No drug interventions Not Available Not Available terminated NCT02230592
PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX No drug interventions Not Available Not Available completed NCT02229188
Games to Overcome Late Life Depression No drug interventions health_services_research Not Available completed NCT02214511
Biomarkers of Social Sensitivity in Major Depression No drug interventions Not Available Not Available completed NCT02209597
Clinical Study of Generic and Brand Bupropion in Depression treatment 4 completed NCT02191124
The Measurement-based Care in Patients With Depressive Disorder: A Randomized Controlled Trial treatment 4 completed NCT02192099
Open Label Extension for GLYX13-C-202, NCT01684163 treatment 2 terminated NCT02185131
Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD. treatment 2 completed NCT02184221
Deep-brain Magnetic Stimulation (DMS) in the Treatment of Major Depressive Disorder No drug interventions treatment Not Available completed NCT02180607
Neuronal Responses to Social Feedback in Major Depressive Disorder No drug interventions Not Available Not Available completed NCT02176824
Chronotherapy Randomized Controlled Trial No drug interventions treatment Not Available terminated NCT02165449
Biomarkers of Fast Acting Therapies in Major Depression treatment 1 completed NCT02158533
A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-4 Study No drug interventions treatment 3 completed NCT02158546
A Study of ALKS 5461 for the Treatment of Major Depressive Disorder (MDD) - the FORWARD-3 Study No drug interventions treatment 3 completed NCT02156622
CID 0911 - Adaptation of A Depression Treatment Intervention for HIV Patients in Cameroon No drug interventions Not Available Not Available completed NCT02149836
Study to Treat Major Depressive Disorder (MDD) With a New Medication treatment 2 completed NCT02141399
A Long-Term Safety Study of ALKS 5461 No drug interventions treatment 3 completed NCT02141776
Comparison of Anodal Transcranial Direct Current Stimulation (t-DCS) and Sham Stimulation in Patients With Treatment-resistant Depression No drug interventions treatment 4 completed NCT02139540
Nitrous Oxide as Treatment for Major Depression - a Pilot Study treatment 2 completed NCT02134808
Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder treatment 4 completed NCT02132286
Serotonin Transporter Genetic Variation and Amygdala Responses to Antidepressant Medications in Major Depression Not Available 4 completed NCT02133001
A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide treatment 2 completed NCT02125799
Accelerated rTMS for Treatment-Resistant Major Depression No drug interventions treatment 2 / 3 completed NCT02099630
Functional and Metabolic Changes in the Course of Antidepressive Treatment No drug interventions Not Available Not Available completed NCT02078817
Ketamine in Adolescents With Treatment-Resistant Depression treatment 2 completed NCT02067793
Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder treatment 2 completed NCT02066077
The Efficacy And Cognitive Impairment Of Modified Electroconvulsive Therapy treatment Not Available completed NCT02055300
Safety, Tolerability and Pharmacokinetics Study of LY03005 treatment 1 completed NCT02053649
Integrated Chronotherapy for Perinatal Depression No drug interventions treatment Not Available completed NCT02051413
Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN) treatment 4 completed NCT02029963
Can Magnetic Brain Stimulation Help Prevent Relapse in Depression? No drug interventions treatment Not Available terminated NCT02028026
The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives treatment 4 withdrawn NCT02024620
Mobile Apps for the Treatment of Depression No drug interventions health_services_research Not Available withdrawn NCT02021149
Enhancing Psychotherapy for Mood Disorders With Whole Body Hyperthermia No drug interventions treatment Not Available terminated NCT02004145
Trial of a Positive Psychology Intervention in Major Depressive Disorder No drug interventions treatment Not Available completed NCT01999010
Mental Health Telemetry for Self-Management in Major Depression No drug interventions treatment Not Available completed NCT01976975
Brain Mechanisms of Human Motivation No drug interventions Not Available Not Available completed NCT01977378
A Study of Sustained-Release Desvenlafaxine Hydrochloride for the Treatment of Major Depressive Disorder treatment 2 / 3 unknown_status NCT01973283
Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults treatment 4 completed NCT01973478
Deep Brain Stimulation in Patients With Chronic Treatment Resistant Depression No drug interventions treatment Not Available completed NCT01957501
Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel No drug interventions Not Available Not Available terminated NCT01947647
Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders No drug interventions treatment Not Available completed NCT01944969
Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder treatment 3 terminated NCT01942785
Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Therapy treatment 3 completed NCT01942187
A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults treatment 4 withdrawn NCT01936506
Cognitive Training for Depression No drug interventions treatment 1 / 2 completed NCT01922219
Predictors of Treatment Outcome With Cognitive Behavioral Therapy for Depression No drug interventions treatment Not Available completed NCT01921543
Deep Brain Stimulation in Treatment Refractory Depression No drug interventions treatment 1 / 2 terminated NCT01919216
Placebo Effects in the Treatment of Depression: Cognitive and Neural Mechanisms treatment 4 completed NCT01919008
Comparison of Plasma Concentration Changes Between Two Types of Tablets of FK949E Administration to Patients With Major Depressive Disorder other 1 completed NCT01916824
Effects of Treatment on Decision-making in Major Depression other 4 completed NCT01896934
Frontal Hypoperfusion Effects on Antidepressant Outcomes in Late-Life Depression basic_science 4 completed NCT01894815
Escitalopram, Placebo and tDCS in Depression: a Non-inferiority Trial treatment 3 completed NCT01890356
Maintenance Transcranial Electrical Stimulation for Depression No drug interventions treatment Not Available completed NCT01890083
A Health Intervention to Prevent Depression Hepatitis C Patients No drug interventions prevention 2 / 3 terminated NCT01882452
A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression No drug interventions treatment Not Available completed NCT01877447
Comparison of Two tDCS Protocols for the Treatment of Major Depressive Disorder No drug interventions treatment Not Available completed NCT01876823
Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment treatment 2 / 3 completed NCT01874951
Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence treatment 2 completed NCT01867749
Group Interpersonal Psychotherapy for Treatment of Major Depressive Disorder Following Perinatal Loss No drug interventions treatment Not Available completed NCT01851967
Effectiveness and Acceptability of MoodGYM in Treating Depressive Symptoms in Chinese Americans No drug interventions treatment Not Available completed NCT01838876
Long-term Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT01838681
Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment treatment 3 completed NCT01837797
Efficacy and Safety of Brexpiprazole as Adjunctive Treatment in Elderly Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment treatment 3 terminated NCT01831882
Identifying Biological Markers for Severe Depression No drug interventions Not Available Not Available completed NCT01828931
Lifestyle Intervention for Diabetes and Weight Management in Psychosis No drug interventions treatment Not Available completed NCT01829165
Brain Imaging of rTMS Treatment for Depression No drug interventions treatment Not Available completed NCT01818453
Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression? No drug interventions treatment Not Available completed NCT01814085
A Safety and Efficacy Study of Escitalopram on Acute Treatment of Severe Depression treatment 4 completed NCT01808651
A Study of Fluoxetine in Major Depressive Disorder (MDD) Long-Term Dosing treatment 3 completed NCT01804270
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1 No drug interventions treatment Not Available terminated NCT01804296
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2 No drug interventions treatment Not Available terminated NCT01793324
EMR Data to Assess Monitoring of Patients Treated With Quetiapine No drug interventions Not Available Not Available completed NCT01787240
Neurobiological Bases of Placebo Response in Major Depressive Disorder treatment 4 terminated NCT01774045
A Dose Escalation Phase I Study of PDC-1421 Capsule Targeting in Depression No drug interventions other 1 completed NCT01752608
Efficacy of Electronic Cognitive Behavioral Therapy Application to Treat Major Depressive Disorder No drug interventions treatment Not Available withdrawn NCT01743716
Genetic and Neural Predictors of Adolescent Depression No drug interventions Not Available Not Available unknown_status NCT01741142
Efficacy and Safety Study of ABT-436 in Major Depressive Disorder treatment 2 terminated NCT01734291
Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression No drug interventions treatment Not Available completed NCT01733654
Investigate Efficacy & Safety of RO4995819 vs. Placebo as Adjunct Tx in Patients w/Major Depressive Disorder treatment 2 withdrawn NCT01731678
Transcranial Magnetic Stimulation for Adolescent Depression No drug interventions treatment Not Available completed NCT01725048
Pilot Study to Evaluate Individualized Choice of Antidepressants in Patients With Cancer supportive_care 0 completed NCT01725282
Study to Evaluate the Effect and Safety of Quetiapine Extended Release (XR) (FK949E) in Major Depressive Disorder treatment 2 completed NCT01724112
Study of the Efficacy and Safety of LY2940094 in Participants With Major Depressive Disorder (MDD) treatment 2 completed NCT01721824
The Effect of IPS-MA- A Modified Early Supported Employment Intervention for Individuals With Mood or Anxiety Disorders No drug interventions Not Available Not Available completed NCT01719315
Neurophysiologic Correlates of Hypersomnia No drug interventions Not Available Not Available completed NCT01715805
Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) treatment 3 completed NCT01701141
Depression and Dopamine Transporter Function Study Using C-11 Altropane No drug interventions Not Available Not Available completed NCT01696617
Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder treatment 4 completed NCT01691092
PET Imaging of mGLuR5 With Drug Challenge other Not Available completed NCT01682785
Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder No drug interventions Not Available Not Available unknown_status NCT01671124
The Study of Antidepressant Properties and Safety of Fer-01(Soline®) on the Patients With Depression No drug interventions Not Available Not Available unknown_status NCT01670279
Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder treatment 1 completed NCT01659814
Dopamine Neurotransmission in Major Depression No drug interventions Not Available Not Available completed NCT01655706
Canadian Biomarker Integration Network for Depression Study diagnostic 3 completed NCT01640483
Differential Efficacy of Supportive and Interpretative Psychodynamic Techniques for Dependent and Self-critical Depressive Patients No drug interventions treatment Not Available completed NCT01633437
Oral Tyramine Pressor Response Study of CX157 Tablets in Healthy Male Volunteers treatment 1 completed NCT01625845
Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED) treatment 2 completed NCT01613820
Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder treatment Not Available withdrawn NCT01608399
Clinical Trial of the Effectiveness of Metacognitive Therapy in the Treatment of Patients With Major Depressive Disorder No drug interventions treatment Not Available completed NCT01608295
Vilazodone for Treatment of Geriatric Depression treatment 4 completed NCT01606384
Evaluation of the Potential Effects of SSR149415 on the Hypothalamic-pituitary-adrenal Axis in Outpatients With Major Depressive Disorder treatment 2 completed NCT01601210
Dose-Ranging Trial of Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder No drug interventions treatment 0 completed NCT01598922
Internet Based Cognitive Behavioral Therapy Effects on Depressive Cognitions and Brain Function No drug interventions treatment Not Available completed NCT01594866
Lexapro®'s Efficacy After Dose Escalation in Remission Study treatment 4 completed NCT01589315
Focal Electroconvulsive Therapy for Depression No drug interventions treatment 2 / 3 completed NCT01583998
Electronic-Measurement Based Care for Major Depressive Disorder No drug interventions treatment Not Available withdrawn NCT01582945
Ketamine Infusion for Treatment-resistant Major Depressive Disorder treatment Not Available completed NCT01582815
A Study of JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms treatment 2 completed NCT01582581
Study of Technology-assisted Treatment of Adolescent Depression No drug interventions treatment Not Available completed NCT01579942
Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression No drug interventions Not Available Not Available terminated NCT01573741
Study of Ketamine as an Antidepressant in Major Depressive Disorder treatment 1 / 2 unknown_status NCT01573598
Safety and Efficacy of Vilazodone in Major Depressive Disorder treatment 4 completed NCT01571453
Study of Vortioxetine (Lu AA21004) in Major Depressive Disorder in Asian Countries treatment 3 completed NCT01559857
Pioglitazone in Patients With Mood Disorders treatment 4 completed NCT01557946
Glutamatergic and GABAergic Mediators of Antidepressant Response in Major Depression treatment 4 completed NCT01556048
Pilot Study of Behavioral Activation for Prolonged Grief No drug interventions treatment 1 completed NCT01542957
Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused Intervention No drug interventions treatment Not Available completed NCT01541475
Neuroimaging Study of Bupropion Treatment in Patients With Major Depressive Disorder treatment 4 completed NCT01538199
Transcranial Laser Therapy for Major Depressive Disorder No drug interventions treatment Not Available completed NCT01533285
Exploratory Study on the Mood and Cytokine Levels in Female Healthy Participants and Major Depressive Disorder Patients treatment 0 completed NCT01517503
Acceptance and Commitment Therapy Versus Cognitive Therapy for the Treatment of Major Depressive Disorder No drug interventions treatment Not Available completed NCT01515215
Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depressive Disorder No drug interventions treatment Not Available completed NCT01514435
Changes in Cerebral Glucose Metabolism After Electroconvulsive Therapy (ECT) No drug interventions treatment Not Available completed NCT01502033
Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed Teens No drug interventions treatment Not Available completed NCT01500200
A Study to Evaluate ALKS 5461 in Subjects With Major Depressive Disorder (MDD) No drug interventions treatment 2 completed NCT01492309
Beat the Blues in Pregnancy Study - Transcranial Magnetic Stimulation No drug interventions treatment Not Available completed NCT01488266
Aripiprazole Augmentation Versus Switching to Different Class of Antidepressants in Major Depressive Disorder treatment Not Available unknown_status NCT01488071
A Study of Vortioxetine (Lu AA21004) in Comparison to Agomelatine in Adults Suffering From Major Depression With Inadequate Response to Previous Medication treatment 3 completed NCT01485887
Venlafaxine ER Long-Term Extension Study for Major Depressive Disorder (MDD) treatment 3 completed NCT01483391
Early Intervention for Youth at Risk for Bipolar Disorder No drug interventions prevention Not Available completed NCT01482221
A Study to Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder treatment 2 completed NCT01478113
Stimulant Enhancement of Well-Being Therapy for Depression treatment Not Available terminated NCT01473615
Mindfulness Based Cognitive Therapy for Chronic Pain and Comorbid Unipolar Depression No drug interventions treatment Not Available unknown_status NCT01473394
Safety, Efficacy, and Tolerability of Vilazodone in Major Depressive Disorder treatment 4 completed NCT01469377
Safety and Efficacy of Cariprazine as an Adjunctive to Antidepressant Therapy in Major Depressive Disorder treatment 2 completed NCT01465165
Use of Multiple Brain Imaging Modalities (PET and MRS) to Identify Metabolic Abnormalities in Major Depression No drug interventions Not Available Not Available terminated NCT01457677
ARTDeCo Study: A Study of RO4995819 in Patients With Major Depressive Disorder And Inadequate Response to Ongoing Antidepressant Treatment treatment 2 completed NCT01450150
Transcranial Direct Current Stimulation as an Augmenting Intervention for Major Depression No drug interventions treatment 2 / 3 unknown_status NCT01443715
A Stepped Care Model of Adolescent Depression Treatment in Primary Care No drug interventions treatment 2 / 3 completed NCT01443208
Pharmacokinetics and Safety of Desvenlafaxine in Korean Healthy Subjects Following Single and Multiple Oral Doses of Desvenlafaxine Succinate Sustained Release Tablet basic_science 1 completed NCT01438242
An Open Label Study of the Genecept™ Assay in Treatment Resistant Depression No drug interventions supportive_care Not Available withdrawn NCT01437657
MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy treatment 2 completed NCT01436162
Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder treatment 3 completed NCT01435759
SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder treatment 2 completed NCT01436175
SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study treatment 3 terminated NCT01436149
Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder treatment 3 completed NCT01430767
Measuring Adherence to Medication for Depression and Attention-deficit Hyperactivity Disorder No drug interventions Not Available Not Available completed NCT01428661
Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder treatment 2 / 3 completed NCT01426997
Phenotype Depression Study No drug interventions Not Available Not Available completed NCT01426516
Pharmacogenomics for Antidepressant Guidance and Education 1 (PAGE-1_AG1) No drug interventions other Not Available terminated NCT01427439
A Prospective Epidemiological Research on Functioning Outcomes Related to Major Depressive Disorder No drug interventions Not Available Not Available completed NCT01424111
Exploring Biomarkers for Depression Not Available Not Available completed NCT01423253
Major Depressive Disorder With Mixed Features - Extension treatment 3 completed NCT01421342
VA Augmentation and Switching Treatments for Improving Depression Outcomes treatment 3 completed NCT01422213
Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive Disorder treatment 3 completed NCT01418638
The Metabolic Effects of Antidepressants in Patients Diagnosed With Major Depressive Disorder No drug interventions Not Available Not Available unknown_status NCT01415154
Maintenance NeuroStar Transcranial Magnetic Stimulation (TMS) in Patients With Major Depressive Disorder No drug interventions treatment Not Available completed NCT01409317
Neural Predictors and Longitudinal Neural Correlates of Deep Transcranial Magnetic Stimulation for Treating Major Depression No drug interventions treatment 2 / 3 completed NCT01409096
Study Using Pregnenolone to Treat Bipolar Depression treatment 4 completed NCT01395147
Long-Term Extension Study of Lu AA21004 in Participants With Major Depressive Disorder treatment 3 completed NCT01392287
Treatment Resistant Geriatric Depression in Primary Care basic_science 1 completed NCT01385709
The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels No drug interventions Not Available Not Available completed NCT01381107
ALK33BUP-201: Safety and Tolerability Study of ALKS 33-BUP (ALKS 5461) Administration in Subjects With MDD Not Available 1 / 2 completed NCT01380691
A Study of LY2216684 in Healthy Participants treatment 1 completed NCT01377194
Safety and Efficacy of Levomilnacipran ER (Levomilnacipran SR) in Major Depressive Disorder treatment 3 completed NCT01371708
A 6-Month Extension Study To The B2061032 Study To Evaluate The Safety, Tolerability, And Efficacy Of DVS SR In The Treatment Of Child And Adolescent Outpatients With MDD treatment 3 completed NCT01372150
A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD treatment 3 completed NCT01371734
A Study Of DVS SR In Treatment Of Children And Adolescent Outpatients With MDD treatment 3 completed NCT01370499
A Study of LY2216684 in Participants With Major Depression Disorder treatment 3 completed NCT01370733
Synchronized Transcranial Magnetic Stimulation (sTMS) in Major Depressive Disorder No drug interventions treatment 3 completed NCT01357083
The Study of Serum Melatonin Rhythm Levels in Patients With Major Depressive Disorder No drug interventions Not Available Not Available completed NCT01353963
Desvenlafaxine Succinate (Pristiq): Postmarketing Surveillance Study Among Filipino Patients Not Available Not Available terminated NCT01344733
A Non Interventional Study to Investigating the Ratio of Mis-diagnosed Bipolar Symptoms in Patient With Major Depressive Disorder (MDD) No drug interventions Not Available Not Available completed NCT01342536
African American Depression Intervention Trial (AADI) No drug interventions treatment 3 completed NCT01342120
PHARMO Institute Seroquel Safety Study No drug interventions Not Available Not Available completed NCT01337609
Study of Probiotic GanedenBC30 for Irritable Bowel Syndrome and Major Depressive Disorder No drug interventions treatment 4 terminated NCT01330485
Deficits in Emotion Regulation Skills as a Maintaining Factor in Major Depressive Disorder No drug interventions treatment Not Available completed NCT01326793
Internet-Based Depression Screening for College Students No drug interventions screening Not Available completed NCT01325532
Efficacy and Safety of Cranial Electrical Stimulation (CES) for Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT01323478
Open-label Safety Extension Study of 15 and 20 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults treatment 3 completed NCT01318434
A Paroxetine- and Placebo-Controlled Study of 50 mg/Day and 100 mg/Day of EB-1010 Among Outpatients With Major Depressive Disorder Who Have Responded Inadequately to Prior Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) treatment 2 / 3 completed NCT01312922
Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD) treatment 3 completed NCT01309776
Comparison of Tianeptine Versus Escitalopram Patients Major Depressive Disorder treatment 4 completed NCT01309542
Long-Term Safety Of DVS-233 SR In Patients With Major Depressive Disorder treatment 3 completed NCT01305889
The Effect of Problem Solving Therapy and Antidepressant Therapy on Cerebral Perfusion and Brain Derived Neurotropic Factor (BDNF) in Depressed Elders treatment Not Available completed NCT01304147
Intranasal Ketamine in Treatment-Resistant Depression treatment Not Available completed NCT01288079
A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder. treatment 2 terminated NCT01275144
A Study of the Effect of LY2216684 on Lorazepam treatment 1 completed NCT01273376
Safety and Efficacy of RX-10100 to Treat Major Depressive Disorder treatment 2 completed NCT01269710
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study No drug interventions Not Available Not Available completed NCT01266590
A Study of LY2216684 and Digoxin in Healthy Subjects treatment 1 completed NCT01263197
A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol treatment 1 completed NCT01263119
A Study of LY2216684 and Warfarin in Healthy Subjects treatment 1 completed NCT01263236
A Study of LY2940094 in Major Depressive Disorder other 1 completed NCT01263093
A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of Clopidogrel treatment 1 completed NCT01263106
A Study of LY2216684 and Theophylline in Healthy Subjects treatment 1 completed NCT01260649
N-methyl-D-aspartate Antagonist (Ketamine) Augmentation of Electroconvulsive Treatment for Severe Major Depression treatment 4 terminated NCT01254305
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder treatment 2 completed NCT01250873
A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline treatment 1 completed NCT01244854
Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness No drug interventions health_services_research Not Available completed NCT01239888
Oxytocin and Tibolone Adjuncts in Treatment Resistant Depression - A Pilot Study treatment 1 unknown_status NCT01226238
Online Self-help for Depressed Patients Awaiting Psychotherapy No drug interventions treatment Not Available terminated NCT01217645
Study to Assess the Distribution, Metabolism and Excretion of [14C]AZD6765 After a Single-Dose Intravenous Administration No drug interventions basic_science 1 completed NCT01211756
Oxytocin Add-on for Stable Depressed Patients treatment Not Available terminated NCT01207271
A Comparison of Cognitive and Dynamic Therapy for Depression in Community Settings No drug interventions treatment Not Available completed NCT01203683
Testing the Effectiveness of a Computer-based Program for Depression No drug interventions treatment 3 completed NCT01198561
Repetitive Transcranial Magnetic Stimulation(rTMS) in the Treatment of Depression No drug interventions Not Available Not Available unknown_status NCT01197508
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder. treatment 3 completed NCT01191333
The Effectiveness of rTMS in Depressed VA Patients No drug interventions treatment Not Available completed NCT01189318
Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder treatment 2 withdrawn NCT01189591
Slow-wave Sleep Deprivation in Depression No drug interventions basic_science Not Available completed NCT01185340
A Study in Participants With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor treatment 3 completed NCT01185977
Biomarkers of Antidepressant Treatment in Adolescents With Major Depression (The Adolescents MDD Study) treatment 4 completed NCT01182103
Epigenetic Regulation of BDNF in Major Depression No drug interventions Not Available Not Available completed NCT01180400
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT01175616
Creatine Augmentation in Veterans With SSRI-Resistant Major Depression treatment 4 withdrawn NCT01162382
Repetitive Transcranial Magnetic Stimulation for Treating Depression: A Functional Magnetic Resonance Imaging Study No drug interventions basic_science Not Available terminated NCT01156415
Open-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD) treatment 3 terminated NCT01157078
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder (MDD) treatment 3 completed NCT01152554
A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT01153347
A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT01149889
Transcranial Direct Current Stimulation to Treat Major Depressive Disorder No drug interventions treatment 2 / 3 completed NCT01149213
Follow-up Study of Transcranial Direct Current Stimulation to Treat Major Depressive Disorder No drug interventions treatment 2 / 3 completed NCT01148979
Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder. treatment 4 completed NCT01145872
The Effects and Mechanisms of Mindfulness Based Cognitive Therapy (MBCT) on Depressive Symptoms and Depression Relapse No drug interventions prevention 3 completed NCT01145755
6-week Study Treatment to Evaluate the Safety and Effectiveness of AZD2066 in Patients With Major Depressive Disorder treatment 2 terminated NCT01140906
Randomised Placebo-controlled Duloxetine-referenced Study of Efficacy and Safety of 15 and 20 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Adults treatment 3 completed NCT01114477
NeuroStar TMS Therapy System: Utilization and Outcomes No drug interventions Not Available Not Available completed NCT01110889
Efficacy, Safety and Tolerability of Agomelatine Sublingual Tablets in the Treatment of Major Depressive Disorder treatment 3 completed NCT01109030
Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder treatment 2 / 3 completed NCT01103271
Pilot Study of Open-label Placebo to Treat Major Depressive Disorder No drug interventions treatment 2 completed NCT01098240
A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression treatment 2 terminated NCT01085812
Relapse-Prevention Study With Levomilnacipran ER (F2695 SR) in Patients With Major Depressive Disorder treatment 3 completed NCT01082237
Biomarkers for Outcomes In Late-life Depression (BOLD) treatment 4 completed NCT01070134
Mindfulness-based Behavioural Therapy (MIBT) Versus Psychodynamic Therapy for Patients With Major Depressive Disorder in Psychotherapeutic Day Treatment. A Randomised Clinical Pilot Trial No drug interventions treatment Not Available unknown_status NCT01070329
A Study in Depression and Associated Painful Physical Symptoms treatment 4 completed NCT01051466
A Study of the Neurobiology of Depression basic_science 4 completed NCT01052077
Study of the Safety and Efficacy of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder treatment 2 completed NCT01043289
Light Therapy for Depression During Pregnancy No drug interventions treatment Not Available completed NCT01034462
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder treatment 3 completed NCT01031810
PET Biomarkers in Treatment Resistant Depression treatment 4 terminated NCT01022632
Effect of Curcumin as Nutraceutical in Patients of Depression treatment Not Available completed NCT01020799
AZD7268 Safety and Tolerability Study treatment 2 completed NCT01001559
Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis Not Available Not Available completed NCT01000805
A Study of Duloxetine in Major Depressive Disorder (MDD) and Associated Painful Symptoms treatment 4 completed NCT00998959
Stress Reduction Intervention for Enhancing Treatment Outcome for Depressed Minority Patients No drug interventions treatment Not Available completed NCT00988663
The Impact of Memantine on Electroconvulsive Therapy (ECT): Will it Improve Response and Protect Against Cognitive Problems? treatment Not Available withdrawn NCT00984087
rTMS for Adolescents and Young Adults No drug interventions treatment 2 withdrawn NCT00973934
Magnetic Seizure Therapy (MST) for the Treatment of Major Depression No drug interventions treatment 2 completed NCT00969150
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder treatment 3 completed NCT00969709
Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Major Depressive Disorder treatment 3 completed NCT00953745
Dopaminergic Effects of Adjunctive Aripiprazole on the Brain in Treatment-Resistant Depression other Not Available completed NCT00952653
Study Evaluating the Effect of Desvenlafaxine on the Pharmacokinetics of Midazolam treatment 4 completed NCT00943033
Study of Mindfulness-Based Cognitive Therapy No drug interventions treatment Not Available completed NCT00939718
Comparison of Vitamin B12 Supplementation to Selective Serotonin Reuptake Inhibitor (SSRI) Versus SSRI Antidepressant Treatment Alone No drug interventions treatment Not Available unknown_status NCT00931775
Citalopram Versus Citalopram Plus Pindolol in Major Depressive Disorder treatment 2 completed NCT00926835
Effect of Antidepressants on the Treatment for Korean Major Depressive Disorder Patients treatment 4 terminated NCT00924976
Improving Representative Payeeship for People With Psychiatric Disabilities and Their Families No drug interventions health_services_research Not Available completed NCT00919932
Using a Text-message System to Engage Depressed Adolescents in Cognitive-behavioral Therapy Homework No drug interventions treatment Not Available completed NCT00905424
Exploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antidepressant treatment 2 completed NCT00889369
Duloxetine for Major Depression in Peri-/Postmenopausal Women treatment 4 unknown_status NCT00887224
Relapse Prevention Study Of Desvenlafaxine Succinate Sustained Release In Outpatients With Major Depressive Disorder treatment 3 completed NCT00885222
Antidepressant Effect of Deep Brain Stimulation in Parkinson's Disease Patients No drug interventions treatment Not Available completed NCT00883519
The Efficacy of Parent Involvement in the Treatment of Adolescent Depression No drug interventions treatment 1 / 2 completed NCT00876343
Study of Aripiprazole as an Adjunctive Therapy in Patients With Major Depressive Disorder treatment 3 completed NCT00873795
Compare the Efficacy and Tolerability of the Combination of Aripiprazole and Selective Serotonin Reuptake Inhibitors (SSRIs) Used in Major Depression treatment Not Available completed NCT00871299
Practicing Alternative Techniques to Heal From Depression: The PATH-D Study No drug interventions treatment Not Available completed NCT00869765
Transcranial Direct Current Stimulation (tDCS) Augmentation by D-Cycloserine as a Treatment for Depression treatment 2 completed NCT00870805
Ultrabrief Pulsewidth Electroconvulsive Therapy (ECT) No drug interventions treatment 4 completed NCT00868374
Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder treatment 3 terminated NCT00863798
Study Evaluating Desvenlafaxine Succinate Sustained Release In Adults With Major Depressive Disorder treatment 3 completed NCT00854100
Safety and Efficacy of Cariprazine As Adjunctive Therapy In Major Depressive Disorder treatment 2 completed NCT00851006
Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram treatment 2 completed NCT00849901
A Study in the Treatment of Children and Adolescents With Major Depressive Disorder treatment 3 completed NCT00849693
A Study in the Treatment of Children and Adolescents With Major Depressive Disorder treatment 3 completed NCT00831415
Study Evaluating Long-Term Safety of Desvenlafaxine Succinate Sustained Release With Japanese Adult Subjects in Major Depressive Disorder (MDD) treatment 3 completed NCT00822744
An Eight-week Study of SSR411298 as Treatment for Major Depressive Disorder in Elderly Patients treatment 2 completed NCT00818506
Associations Between Depression and Cardiovascular Disease - a Study of Patients With Late Onset Depression No drug interventions Not Available Not Available completed NCT00816322
The Effect of Fish Oil in Major Depressive Disorder No drug interventions prevention Not Available completed NCT00812227
Neural Correlates of Psychodynamic Psychotherapy for Depression No drug interventions treatment Not Available completed NCT00811252
Randomised Placebo-controlled Duloxetine-referenced Study of Efficacy and Safety of 5 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder in Elderly Patients treatment 3 completed NCT00809770
Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill No drug interventions treatment Not Available completed NCT00807105
Evaluation of the H-coil Transcranial Magnetic Stimulation TMS Device - Safety and Feasibility Study for Acute and Maintenance Treatment in Major Depressive Episode No drug interventions treatment 2 completed NCT00807248
Short-term Study of Combination Treatment of Escitalopram and Gaboxadol in Major Depressive Disorder treatment 2 completed NCT00798707
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) in the Treatment of Major Depressive Disorder treatment 3 completed NCT00789854
Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients treatment 3 completed NCT00788918
Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS) Not Available Not Available completed NCT00785434
Efficacy and Safety of Escitalopram Doses up to 50mg in Treatment of MDD treatment 4 completed NCT00782964
Antidepressant Incomplete Response Depression No drug interventions Not Available Not Available completed NCT00781677
Using Neuroimaging to Investigate Major Depressive Disorder No drug interventions Not Available Not Available completed NCT00781742
AZD6765 Severe Major Depressive Disorder (MDD) IV treatment 2 completed NCT00775203
A Randomized, Double-blind, Two-arm Study Comparing the Efficacy and Safety of Trazodone Contramid® OAD and Placebo in the Treatment of Unipolar Major Depressive Disorder. treatment 3 completed NCT00766870
Efficacy and Safety of Lu AA34893 in Patients With Major Depressive Disorder treatment 2 terminated NCT00761306
Open-label Safety Extension Study of 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults treatment 2 completed NCT00744406
Patient Dimensions as Predictors of Varied Treatment Responses and Outcomes in Patients With Major Depression treatment 2 completed NCT00745017
Stress Generation and Recurrent Depression: The Role of Differential Treatment Response No drug interventions treatment 1 completed NCT00742573
Incorporating Patient Treatment Choice to Improve Treatment Retention in Depressed Hispanics treatment 2 completed NCT00739908
A Study of CX157 (TriRima) for the Treatment of Depression treatment 2 completed NCT00735709
Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder treatment 3 completed NCT00733668
Efficacy of SEROQUEL in Selective Serotonin Reuptake Inhibitors (SSRI)-Resistant Major Depressive Disorder treatment 2 completed NCT00731653
Open Label Extension Assessing the Tolerability of BCI-024 in Combination With BCI-049 in Patients With Major Depressive Disorder (MDD) treatment 2 completed NCT00729755
Creatine Augmentation Treatment in Major Depressive Disorder Subjects No drug interventions treatment Not Available completed NCT00723970
Quetiapine Extended Release (XR) for the Treatment of Menopausal Depression treatment 4 completed NCT00715559
Cysteamine Therapy for Major Depressive Disorder treatment Not Available terminated NCT00705185
Exploring a Potential Blood Test to Diagnose Major Depressive Disorder No drug interventions Not Available Not Available completed NCT00696293
Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults treatment 4 completed NCT00694304
Open-label Safety Extension Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults treatment 3 completed NCT00693849
International Study to Predict Optimised Treatment - in Depression health_services_research 4 unknown_status NCT00692445
TC-5214 as add-on the Treatment of Major Depressive Disorder treatment 2 completed NCT00688818
Quetiapine in Co-Morbid Depressive and Anxiety Disorders treatment Not Available completed NCT00683852
A Double-Blind, Placebo-Controlled Study of Aripiprazole Adjunctive to Antidepressant Therapy treatment 3 completed NCT00659347
Efficacy and Safety of DOV 21,947 in the Treatment of Major Depressive Disorder No drug interventions treatment 2 terminated NCT00644358
A One Year Open Label Study Assessing the Safety and Tolerability of Vilazodone in Patients With Major Depressive Disorder (MDD) treatment 3 completed NCT00642694
Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon treatment 3 terminated NCT00635219
Randomised Placebo-controlled Duloxetine-referenced Efficacy and Safety Study of 2.5, 5 and 10 mg of Vortioxetine (Lu AA21004) in Acute Treatment of Major Depressive Disorder treatment 3 completed NCT00633399
Ziprasidone Augmentation of SSRIs for Patients With Major Depressive Disorder (MDD) That do Not Sufficiently Respond to Treatment With SSRIs treatment 2 completed NCT00628914
Brain Mechanisms and Targeting Insomnia in Major Depression treatment 4 unknown_status NCT00621270
Safety and Effectiveness Study of BCI-540 Versus Placebo in the Treatment of Major Depressive Disorder With Concomitant Anxiety No drug interventions treatment 2 completed NCT00619619
Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Child And Adolescent Outpatients With Major Depressive Disorder Not Available 2 completed NCT00617045
Duloxetine for the Treatment of Postpartum Depression treatment Not Available withdrawn NCT00612807
Treatment of Mood and Marriage Study (TOMMS) treatment 1 / 2 completed NCT00610259
Brief Behavioral Therapy for Insomnia (bBT-I) for Depressed Outpatients With Refractory Insomnia No drug interventions treatment 2 / 3 completed NCT00609453
Brain Imaging of Psychotherapy for Depression No drug interventions Not Available Not Available completed NCT00599911
Dose-finding Study With Lu AA24530 in Major Depressive Disorder treatment 2 completed NCT00596817
Efficacy of Vortioxetine (Lu AA21004) in the Prevention of Relapse of Major Depressive Episodes treatment 3 completed NCT00581009
The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients treatment 1 / 2 completed NCT00578669
Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms treatment 3 completed NCT00578383
Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device No drug interventions treatment Not Available completed NCT00570050
Effect of Intranasal Insulin on Depressive Symptoms in Major Depressive Disorder treatment 3 completed NCT00561509
Multi-Country Observational Study to Collect the Frequency of Sexual Dysfunction With Antidepressant Treatment, Either With SSRIs or Duals at 8 Weeks and 6 Months No drug interventions Not Available Not Available completed NCT00562367
Biochemical Brain Changes Correlated With The Antidepressant Effect Of Thyroid Hormones basic_science Not Available completed NCT00555997
A 12-Week, Placebo Controlled Trial of Ziprasidone as Monotherapy for Major Depressive Disorder treatment 2 completed NCT00536471
A Study Comparing Duloxetine and Placebo in Assessing Energy and Vitality in Major Depressive Disorder (MDD) Patients treatment 4 completed NCT00533832
Pivotal Trial (D02) of Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression (TRD) No drug interventions treatment Not Available completed NCT00531947
Phase IV:Safety and Efficacy of EMSAM in Adolescents With Major Depression treatment 4 completed NCT00526383
Do Antidepressants Induce Metabolic Syndromes METADAP Study No drug interventions treatment Not Available completed NCT00521352
Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Panic Disorder With Comorbid Major Depression No drug interventions treatment 2 completed NCT00518986
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression treatment 4 completed NCT00519428
Does Dual Therapy Hasten Antidepressant Response? treatment 4 completed NCT00517985
Duloxetine for Perimenopausal Depression treatment 4 completed NCT00505518
Investigating the Effectiveness of Telepsychiatry for Treating Major Depression in a Chinese American Nursing Home No drug interventions treatment Not Available completed NCT00489775
Duloxetine Versus Paroxetine for Major Depression treatment 3 completed NCT00485420
eCare for Moods: An Internet-based Management Program No drug interventions health_services_research Not Available completed NCT00479726
Lilly's Emotional and Physical Symptoms of Depression Study (LEAPS) treatment 4 completed NCT00474708
Study Comparing the Efficacy of Venlafaxine XR Vs. SSRIs and Conventional Antidepressants in Depressed Patients treatment 4 completed NCT00467402
Efficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive Disorder prevention 3 completed NCT00464711
Brain GABA Levels and Treatment Response in Major Depressive Disorder treatment 4 completed NCT00463242
A Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD) treatment 3 completed NCT00452595
Study Evaluating DVS-233 for Treatment of Outpatients With Major Depressive Disorder treatment 3 completed NCT00452543
Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism treatment 4 completed NCT00432614
Efficacy and Safety of SR58611A co-Administered With Escitalopram in Adults With Major Depressive Disorder treatment 3 completed NCT00433238
Screening for Mental Health Concerns for at-Risk Community Living Chinese Seniors No drug interventions screening 1 unknown_status NCT00422162
A Study Evaluating Duloxetine in Patients Hospitalized for Severe Depression treatment 4 completed NCT00421369
Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response. treatment Not Available completed NCT00414323
Evaluation of the Effects of Duloxetine on Norepinephrine treatment 1 completed NCT00411099
Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder treatment 3 completed NCT00404755
Dichotic Listening as a Predictor of Medication Response in Depression treatment 4 completed NCT00402220
A Double-blind Sham Controlled Trial of rTMS in Treatment Resistant Major Depression No drug interventions treatment Not Available completed NCT00400088
Lithium Versus Paroxetine in Patients With Major Depression Who Have a Family History of Bipolar Disorder or Suicide treatment 3 terminated NCT00385307
Efficacy and Safety of SR58611A in Patients With Major Depressive Disorder (SIRIUS) treatment 3 completed NCT00384436
Fixed Dose Comparison of Escitalopram to an Active Comparator in Severely Depressed Patients treatment 4 completed NCT00377299
A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence treatment Not Available completed NCT00373477
A Study of the Cost Effectiveness of Generalist Care Managers for Depression Treatment in Medicaid Recipients No drug interventions treatment Not Available completed NCT00369798
Antidepressant Effects on cAMP Specific Phosphodiesterase (PDE4) in Depressed Patients treatment 1 completed NCT00369746
STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse Not Available Not Available completed NCT00367341
Imaging Predictors of Treatment Response in Depression treatment Not Available completed NCT00361218
Biological Markers of Response to Treatment in Major Depressive Disorder treatment 3 completed NCT00360256
Genetic Study of Liver Enzymes in Patients With Side Effects From Antidepressants No drug interventions Not Available Not Available completed NCT00353028
Fluvoxamine Maleate in the Treatment of Depression/Depressive State : A Post-marketing Clinical Study in Children and Adolescents treatment 4 completed NCT00351910
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder treatment 3 completed NCT00335205
A Placebo Controlled Trial of the Dopamine D-2 Receptor Agonist Ropinirole in Treatment of 60 Patients With Refractory Bipolar Depression. treatment 4 unknown_status NCT00332670
Light Therapy for Elderly Depression No drug interventions treatment 2 / 3 terminated NCT00331799
Pilot Study of Duloxetine in Psychological Resilience treatment 2 completed NCT00326105
Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive Disorders treatment 3 completed NCT00326144
Efficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in the Treatment of Major Depressive Disorders treatment 3 completed NCT00321152
A Study of 6(S)-5-MTHF Among Serotonin Reuptake Inhibitor(SSRI)-Resistant Outpatients With Major Depressive Disorder (MDD) No drug interventions treatment 4 completed NCT00320372
Treatment-Resistant Depression Registry No drug interventions Not Available Not Available completed NCT00320268
Safety & Efficacy Study of Quetiapine Fumarate (SEROQUEL®) vs. Placebo in Major Depressive Disorder treatment 3 completed NCT00313417
Creatine as a New Therapeutic Strategy in Depression No drug interventions treatment 4 terminated NCT00305045
Treating Refractory Major Depressive Disorder With Repetitive Transcranial Magnetic Stimulation No drug interventions treatment Not Available completed NCT00296933
Memory Functioning and Antidepressant Treatment treatment 3 completed NCT00278941
Quetiapine Fumarate as Monotherapy in the Maintenance Treatment of Patients With Major Depressive Disorder treatment 3 completed NCT00277823
Study Evaluating Desvenlafaxine Sustained-Release (DVS-SR) in Adult Outpatients With Major Depressive Disorder No drug interventions treatment 3 completed NCT00262665
Randomized, Placebo-controlled Trial of an AMPAkine in Major Depressive Disorder treatment 2 withdrawn NCT00252330
Efficacy and Safety of SR58611A in Patients With Major Depressive Disorder treatment 3 completed NCT00252356
Efficacy and Safety of SR58611A in Patients With Major Depressive Disorder treatment 3 completed NCT00245557
Magnetic Resonance Imaging Study of Geriatric Depression treatment Not Available completed NCT00243425
Patient-Centered Depression Care for African Americans No drug interventions treatment Not Available unknown_status NCT00242229
Study Evaluating DVS-233 SR in Elderly Outpatients With Major Depressive Disorder Not Available Not Available completed NCT00239954
Escitalopram Combination Comparison Study for Adult Patients With Major Depressive Disorder treatment 3 unknown_status NCT00232700
Investigation of a Combination Treatment of Escitalopram and rTMS treatment Not Available completed NCT00229398
Medical and Psychiatric Co-Morbidity Among Treatment Resistant Patients With Major Depression Disorder No drug interventions Not Available Not Available completed NCT00226278
Safety Study of ORG 34517 for Major Depression With Psychotic Features treatment 2 completed NCT00223197
Pregnenolone Trial for Depression in Bipolar Disorders or Recurrent Major Depressive Disorder With Substance Abuse treatment 4 completed NCT00215228
Effects of Duloxetine vs. Escitalopram on Heart Rate Variability in Depression treatment 2 / 3 completed NCT00208169
Abilify Therapy for Reducing Comorbid Substance Abuse treatment 4 completed NCT00208897
Does Fluoxetine Have an Effect on the CNS CRF Systems in Women Abused in Childhood? treatment Not Available completed NCT00209066
Treatment of Reduced Heart Rate Variability Associated With Major Depression With Electroconvulsive Therapy No drug interventions Not Available Not Available completed NCT00209105
Characterizing Psychological Consequences of Childhood Trauma No drug interventions Not Available Not Available completed NCT00205933
Behavioral Processes Underlying Reward Processing in Depression No drug interventions Not Available Not Available completed NCT00204152
Treatment for Chronic Depression No drug interventions treatment 3 terminated NCT00191594
Open-Label Duloxetine Extension Phase in Patients Who Have Completed Previous Duloxetine Trials treatment 3 completed NCT00191932
Switching to Duloxetine From Other Antidepressants treatment 4 completed NCT00188942
A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder diagnostic 4 completed NCT00186446
Treatment of Nicotine Dependence and Acute Depression treatment 4 completed NCT00182533
Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood Disorders treatment 4 terminated NCT00179283
Sertraline vs. Venlafaxine XR treatment 3 completed NCT00168272
Priming rTMS In Major Depression No drug interventions treatment Not Available completed NCT00168376
A Randomised Double-Blind Trial of Targeted Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder No drug interventions educational_counseling_training Not Available completed NCT00166114
Depression, Epinephrine, and Platelet Function treatment 4 completed NCT00157547
Quantitative EEG (QEEG) as a Predictor of Treatment Outcome in Depression treatment 4 completed NCT00149825
Combining Antidepressant Medication and Psychotherapy for Insomnia to Improve Depression Outcome treatment 2 completed NCT00146523
An International Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression treatment 3 completed NCT00130676
A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression treatment 3 completed NCT00128479
A United States Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression treatment 3 completed NCT00128505
An International Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression treatment 3 completed NCT00125554
Metyrapone as Additive Treatment in Major Depression treatment 2 completed NCT00108407
Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse No drug interventions Not Available Not Available completed NCT00108979
Study of Escitalopram in Adult Patients With Major Depressive Disorder treatment 3 completed NCT00104611
Study of a Repetitive Transcranial Magnetic Stimulation (rTMS) Device for the Treatment of Major Depressive Disorder No drug interventions treatment 3 completed NCT00095745
A Long-Term Study of Aripiprazole in Patients With Major Depressive Disorder treatment 3 completed NCT00096642
Cognitive Behavioral Therapy for Early-Onset Depression No drug interventions treatment Not Available completed NCT00095758
A Study of Adjunctive Aripiprazole in Patients With Major Depressive Disorder treatment 3 completed NCT00095134
Study Comparing Adjunctive Risperidone Versus Placebo in Major Depressive Disorder That Is Not Responding to Standard Therapy treatment 3 completed NCT00092911
Study Evaluating DVS-233 SR in Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00090649
Study Evaluating DVS-233 SR And Venlafaxine ER In Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00087737
Study Evaluating DVS-233 SR and Venlafaxine ER in Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00075296
FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression No drug interventions Not Available Not Available completed NCT00073203
A 6 Week Study to Determine the Effectiveness of R228060 in Adult Subjects With Major Depressive Disorder treatment 2 completed NCT00072774
Study Evaluating DVS-233 SR In Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00063206
Study Evaluating DVS-233 in Adult Outpatients With Major Depressive Disorder treatment 3 completed NCT00059579
Brain Regulation of Emotions in People With Depression and Anhedonia No drug interventions Not Available Not Available completed NCT00049972
Major Depressive Disorder Study In Adults treatment 4 completed NCT00048594
Long Term Treatment of Patients With Major Depressive Disorder With MK0869 (0869-065)(COMPLETED) treatment 3 completed NCT00048607
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-062)(COMPLETED) treatment 3 completed NCT00042575
Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression treatment 3 completed NCT00042562
Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression treatment 3 completed NCT00042029
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-073) treatment 3 completed NCT00035009
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-059) treatment 3 completed NCT00034983
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-066)(COMPLETED) treatment 3 completed NCT00034944
Treatment of Patients With Major Depressive Disorder With MK0869 (0869-063) treatment 3 completed NCT00000375
Continuation Electroconvulsive Therapy Vs Medication to Prevent Relapses in Patients With Major Depressive Disorder treatment 4 completed NCT04701840
Accelerated TBS for Adolescent Suicidal Ideation No drug interventions treatment Not Available not_yet_recruiting NCT03401164
Target Engagement of D-cycloserine (DCS) treatment 2 not_yet_recruiting NCT00479414
Lilly's Emotional and Physical Symptoms of Depression Study treatment 4 completed NCT00479453
Lilly's Emotional and Physical Symptoms of Depression treatment 4 completed NCT02559947
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder diagnostic 4 not_yet_recruiting NCT00843674
Psychotherapy for Depressed Women With Abuse Histories No drug interventions treatment 2 completed NCT02348411
A Feasibility Study to Evaluate Safety and Initial Effectiveness of ExAblate Transcranial MR Guided Focused Ultrasound for Bilateral Anterior Capsulotomy in the Treatment of Medication-Refractory MDD No drug interventions treatment Not Available completed NCT03406052
Smartphone-enabled Health Coaching Intervention for Youth Diagnosed With Major Depressive Disorders No drug interventions supportive_care Not Available suspended NCT00825058
Efficacy and Safety of SR58611 Compared to Placebo and Paroxetine treatment 3 completed NCT01347138
Health Care Management for the Elderly in Community Through Screening No drug interventions screening Not Available completed NCT06239740
Effects of Electroacupuncture on Cognitive Symptoms in Major Depressive Disorder No drug interventions treatment Not Available completed NCT04497493
Efficacy of Transcranial Direct Current Stimulation (tDCS) for the Treatment of Major Depressive Disorder No drug interventions treatment Not Available recruiting NCT02972398
N-Acetyl Cysteine Supplementation in Therapy Refractory Major Depressive Disorders treatment Not Available recruiting NCT02942251
Relapse Predicting Model for First Episode Depression No drug interventions prevention Not Available unknown_status NCT02829671
Loneliness and Occurrence of Suicide Attempts and Suicidal Ideas No drug interventions other Not Available completed NCT02681822
Multi-center Imaging Genetics Studies in China No drug interventions Not Available Not Available unknown_status NCT02590185
MetAbolism vaRiability of VEnLafaxine No drug interventions treatment Not Available unknown_status NCT02449447
Blended Depression Therapy: Cognitive Behaviour Therapy Face-to-face and Via Internet No drug interventions treatment Not Available completed NCT01377896
The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription Behaviours No drug interventions Not Available Not Available completed NCT00855530
Long Term Safety and Tolerability of SR58611 in Patients With Major Depressive Disorder treatment 3 completed NCT00825019
Efficacy and Safety of One Single Dose of SR58611 Compared to Placebo and Paroxetine treatment 3 completed NCT04482296
Effect of Zinc Supplementation on Depression in SSRI-treated Major Depressive Disorder Patients treatment Not Available completed NCT04279522
The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD) No drug interventions treatment Not Available completed NCT01808976
Can Mental Health Apps Work in the Real World? A Feasibility Pilot Study. No drug interventions other Not Available completed NCT04880460
Effect of Magnesium Supplementation in Selective Serotonin Reuptake Inhibitors Treated Major Depressive Disorder Patients No drug interventions treatment 2 completed NCT04076644
Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder No drug interventions treatment Not Available completed NCT06572683
Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder No drug interventions treatment Not Available enrolling_by_invitation NCT05169346
Neurofeedback to Treat Depression No drug interventions treatment Not Available recruiting NCT06319378
Cancer Related Major Depression Treated With a Single Dose of Psilocybin treatment 2 recruiting NCT06130371
Stress, Inflammation and Neuroimaging in Major Depressive Disorder as Compared to Premenstrual Dysphoric Disorder No drug interventions Not Available Not Available recruiting NCT06261177
Take-home Functional Electrical Stimulation for MDD No drug interventions treatment Not Available active_not_recruiting NCT05537285
Individualized Neuromodulation for Anhedonic Depression No drug interventions treatment Not Available recruiting NCT05528315
SAD/MAD of ABX-002-1902 Investigating the Safety, Pharmacokinetics/Pharmacodynamics of in Healthy Subjects treatment 1 completed NCT04226352
Three Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive Disorder other 1 completed NCT04220996
Vortioxetine in Patients With Depression Coexisting With General Anxiety Disorder (GAD) treatment 4 completed NCT04071886
Effect of Short-Term Mindfulness-Based Training For Major Depression Disorder: An Eye-Tracking Study No drug interventions treatment Not Available unknown_status NCT03971305
A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With Systemic ALK(+) ALCL No drug interventions Not Available Not Available recruiting NCT03765138
Combined Treatment of Prolonged Exposure and Pramipexole for Posttraumatic Stress Disorder and Depression treatment 3 terminated NCT03754712
Effect of Vitamin D Administration Along With SSRIs in Patients With Major Depressive Disorder No drug interventions treatment Not Available unknown_status NCT03126682
Effect of Bupropion on Seizure Threshold in Depressed Patients treatment 4 completed NCT03083340
Implementation of a Self-Help Depression Program Among Orthopedic Patients No drug interventions treatment Not Available withdrawn NCT02013609
Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work Environment treatment 3 completed NCT01913366
Senior Peer Alliance for Rural Research On Wellness No drug interventions treatment Not Available completed NCT01501812
Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders No drug interventions Not Available Not Available unknown_status NCT01190514
Phase 1 Study To Test the Bioequivalence Between Two 25 mg Tablets vs. One 50 mg Tablet Under Fast/Fed Condition and Evaluate Food Effect of Desvenlafaxine Succinate Sustained Release (DVS SR) treatment 1 completed NCT04405791
Efficacy of Clinical Application of Transcranial Low Intensity Focused Ultrasonic Stimulation for Patients With Major Deperessive Disorder - Exploratory Clinical Trial No drug interventions treatment 3 completed NCT00330616
Study Of Bupropion SR (323U66) In Patients With Major Depressive Disorder In Japan No drug interventions treatment 2 completed NCT01594996
European Drug Utilization Study No drug interventions Not Available Not Available completed NCT05762458
The Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression No drug interventions treatment 2 not_yet_recruiting NCT01701258
An Investigation of Early Life Stress and Depression basic_science 1 completed NCT05504486
Open-label Brexpiprazole fMRI Trial in Adults With Major Depressive Disorder and Anxiety basic_science 4 withdrawn NCT00960986
A Duloxetine Dosing Strategy Study in Korean Patients With Major Depressive Disorder treatment 4 completed NCT02109939
Genomics Used to Improve DEpression Decisions No drug interventions treatment Not Available completed NCT00057239
An 8 Week Depression Study In Adults Diagnosed With Major Depressive Disorder treatment 2 completed NCT03874130
Scopolamine in Healthy Volunteers treatment 1 unknown_status NCT02380066
Comparison of Anyu Peibo With Placebo in Treatment of MDD No drug interventions treatment 2 completed NCT04403373
Effectiveness of Walking Exercise in Improving Depression in Older Adults With Major Depressive Disorder, A Pilot Study No drug interventions treatment Not Available completed NCT00448292
A Efficacy Study of PRX-00023 in Patients With Major Depressive Disorder treatment 2 completed NCT00064467
Lethargic Depression Study treatment 3 completed NCT02015546
Switching From Generic Selective Serotonin Reuptake Inhibitors (SSRIs) and Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs) to Three Different Dose Initiation Strategies With Vilazodone treatment 3 completed NCT03642964
A Study in Patients With Major Depressive Disorder No drug interventions treatment 2 active_not_recruiting NCT01253421
The Effects of Dopamine on Reward Processing treatment 1 completed NCT02191384
Comparison of Orcinoside With Placebo in Treatment of MDD No drug interventions treatment 2 completed NCT06409325
Effectiveness of MST Versus ECT for Major Depressive Episode No drug interventions treatment Not Available recruiting NCT06385405
Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment No drug interventions treatment Not Available recruiting NCT06044818
Validation of Accexible as a Tool for Screening and Monitoring Depression. No drug interventions Not Available Not Available recruiting NCT05966532
Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression No drug interventions Not Available Not Available recruiting NCT05938179
A Study of HS-10353 in Adult Participants With Major Depressive Disorder No drug interventions treatment 2 not_yet_recruiting NCT05417087
Single Dose Oral Bioequivalence Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets treatment 1 completed NCT05416957
Food Effect Bioavailability Study of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets No drug interventions treatment 1 completed NCT05541302
Retrospective TMS Therapy for Adults With MDD No drug interventions Not Available Not Available completed NCT05018013
Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression treatment 2 recruiting NCT04853407
A Study to Evaluate the Efficacy and Safety of Ansofaxine Hydrochloride Extended-release Tablets in the Treatment of Major Depressive Disorder (MDD) treatment 3 completed NCT03012724
Efficacy of H7-Coil DTMS Compared to H1-Coil DTMS in Subjects With Major Depression Disorder (MDD) No drug interventions treatment Not Available unknown_status NCT02395263
Comparison of Yuxintine With Placebo in Treatment of MDD No drug interventions treatment 2 unknown_status NCT02012218
Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adjunctive Therapy treatment 3 completed NCT01912196
Add-On Study of MSI-195 (S-Adenosyl-L-Methionine, SAMe) for Patients With Major Depressive Disorder (MDD) No drug interventions treatment 2 completed NCT01790919
Improving Depression Outcome by Enhancing Memory for Cognitive Therapy No drug interventions treatment 2 completed NCT01683019
Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression No drug interventions treatment Not Available completed NCT01483053
Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD) treatment 4 unknown_status NCT01477203
Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders diagnostic 4 completed NCT01187407
A Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) Treatment treatment 3 completed NCT01123707
To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) treatment 3 terminated NCT01111539
Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) treatment 3 terminated NCT01111565
Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) treatment 3 terminated NCT01111552
Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD) treatment 3 terminated NCT00958204
Light, Ion, and Fluoxetine Efficacy (LIFE) in Depression treatment 3 completed NCT00839176
Efficacy Study of RX-10100 to Treat Major Depressive Disorder (MDD) treatment 2 completed NCT00768430
Optimization of IV Ketamine for Treatment Resistant Depression treatment 2 completed NCT00702598
The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working People No drug interventions treatment Not Available completed NCT00411242
Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder treatment 3 completed NCT00051272
Effects Of Antidepressants On Sexual Functioning In Adults treatment 3 completed NCT00051259
Effects of Antidepressants on Sexual Functioning treatment 3 completed NCT01944657
Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study No drug interventions treatment Not Available withdrawn NCT02474680
Evaluation of Pharmacogenetic Testing In a Mental Health Population and Economic Outcomes No drug interventions Not Available Not Available completed NCT01525524
Treatment of Major Depressive Disorder Post Stroke With Transcranial Direct Current Stimulation No drug interventions treatment 2 completed