Post-Poliomyelitis Syndrome (DBCOND0037338)

Identifiers

Synonyms

Post-Poliomyélitis Syndrom / Postpoliomyelitis Syndrome / Postpolio Syndrome / Post Polio Syndrome, PPS / Post polio syndrome / Post-Polio Syndrome / Post poliomyelitis syndrome (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Pyridostigmine	A cholinesterase inhibitor used for symptomatic treatment of myasthenia gravis and congenital myasthenic syndromes and to reverse neuromuscular blockade by nondepolarizing muscle relaxants.	Acetylcholinesterasetarget Cholinesterasetarget Acetylcholinesteraseenzyme Cholinesteraseenzyme Cytochrome P450 3A4enzyme Coagulation factor Xtarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04004390	Treatment of Post-poliomyelitis Syndrome by Intravenous Immunoglobulin	No drug interventions	Not Available	Not Available	completed
NCT00004553	Electromyography to Diagnose Neuromuscular Disorders	No drug interventions	Not Available	Not Available	completed
NCT00001185	Study of "Post-Polio Syndrome"	No drug interventions	Not Available	Not Available	completed
NCT01271530	Arm Cycling to Improve Fitness in Polio Survivors	No drug interventions	treatment	Not Available	completed
NCT06320444	Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease	No drug interventions	Not Available	Not Available	recruiting
NCT05663008	Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis	No drug interventions	Not Available	Not Available	recruiting
NCT01549847	A Randomized, Double Blind, Placebo Controlled Trial L-carnitine and Piracetam in the Treatment of Weakness, Muscle Fatigue and Muscle Pain in the Postpoliomyelitis Syndrome	Levocarnitine Piracetam	treatment	3	withdrawn
NCT00067496	Modafinil to Treat Fatigue in Post-Polio Syndrome	Modafinil	treatment	3	terminated
NCT00487487	Study of Mental Fatigue in Polio Survivors	No drug interventions	Not Available	Not Available	unknown_status
NCT04387864	Whole Body Vibration on Muscle Strength in Patients With Postpolio Syndrome	No drug interventions	treatment	Not Available	completed
NCT00160082	Efficacy and Safety of Xepol (Human Immunoglobulin) in Subjects With Post-Polio Syndrome (PPS)	No drug interventions	treatment	Not Available	completed
NCT02176863	Study of the Efficacy and Safety of Immune Globulin Intravenous (Human) Flebogamma® 5% DIF in Patients With Post-polio Syndrome	Human immunoglobulin G	treatment	2 / 3	terminated
NCT00231439	Post-Poliosyndrome Treated With Intravenous Immunoglobulin (IvIg)	No drug interventions	treatment	2 / 3	completed
NCT03561623	Spinal Cord Gray Matter Imaging in Post Polio Syndrome	No drug interventions	Not Available	Not Available	unknown_status
NCT03064711	Activity and Fatigue of the Respiratory Muscles and Pulmonary Characteristics in Post-Polio Patients	No drug interventions	basic_science	Not Available	completed
NCT02801071	L-Citrulline in Patients With Post-Polio Syndrome	Citrulline	treatment	3	completed
NCT02815878	Enhance Wellness for Individuals With Long-Term Physical Disabilities	No drug interventions	health_services_research	Not Available	completed
NCT02089880	Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis	No drug interventions	supportive_care	Not Available	active_not_recruiting
NCT01537575	Intravenous Immunoglobulins for Post-Polio Syndrome	Human immunoglobulin G	treatment	3	completed
NCT01402570	Glutathione and Health With Post-Polio Syndrome	No drug interventions	treatment	Not Available	completed
NCT05644522	Nomad P-KAFO Study	No drug interventions	treatment	Not Available	recruiting