NCT06606418
Effect of Acupuncture for Rapid Eye Movement Sleep Behavior Disorder No drug interventions treatment Not Available not_yet_recruiting NCT04020198
A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies No drug interventions Not Available Not Available unknown_status NCT05307770
Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder No drug interventions supportive_care Not Available terminated NCT00817726
RBD Longitudinal as Prognostic for PD No drug interventions Not Available Not Available active_not_recruiting NCT04534023
A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies treatment 2 recruiting NCT04886076
Sleep Profiles in REM Sleep Behavior Disorder No drug interventions Not Available Not Available unknown_status NCT04266457
Establishing Alpha-synuclein RT-QuIC Assay as a Diagnostic Technique in REM Sleep Behaviour Disorder No drug interventions Not Available Not Available withdrawn NCT06600438
Slowing Parkinson's Early Through Exercise Dosage - United Kingdom No drug interventions prevention 0 not_yet_recruiting NCT04048603
Search for Biomarkers of Neurodegenerative Diseases in Idiopathic REM Sleep Behavior Disorder No drug interventions Not Available Not Available unknown_status NCT05109364
Terazosin and Parkinson's Disease Extension Study treatment 2 recruiting NCT06441864
Behavioral Treatment for Nightmares in REM Sleep Behavior Disorder No drug interventions treatment Not Available recruiting NCT03671798
Establish a National Registry of REM Sleep Behavior Disorder No drug interventions Not Available Not Available unknown_status NCT01674998
Understanding the Natural History of REM Sleep Behavior Disorder No drug interventions Not Available Not Available unknown_status NCT06467461
Identification of Prodromal Neurodegeneration in Serotonergic-Induced REM Sleep Behavior Disorder No drug interventions basic_science Not Available recruiting NCT05721911
Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology No drug interventions Not Available Not Available not_yet_recruiting NCT03133611
Detecting Parkinson's Disease Through Speech Analysis No drug interventions diagnostic Not Available unknown_status NCT06140511
DREAMER - IsolateD REM Sleep Without Atonia as a Risk Factor for REM Sleep Behavior disordER No drug interventions Not Available Not Available not_yet_recruiting NCT02984137
Prospective Neuroimaging Investigation of Idiopathic REM Sleep Behavior Disorder No drug interventions diagnostic Not Available completed NCT03595475
Prodromal Markers of First-degree Relatives of Patients With Psychiatric Disorders Comorbid With RBD No drug interventions Not Available Not Available completed NCT05514106
MIBG in Aging and Neurologic Disorders No drug interventions diagnostic 4 enrolling_by_invitation NCT05904717
Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder treatment 2 recruiting NCT04386317
Terazosin Effect on Cardiac Changes in Early Parkinson's Disease treatment 2 recruiting NCT03775096
Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136) treatment 2 recruiting NCT02640339
Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease No drug interventions Not Available Not Available completed NCT02554331
Gait and REM Sleep Behavior Disorder No drug interventions diagnostic Not Available terminated NCT01453127
DaTSCAN Imaging in Aging and Neurodegenerative Disease diagnostic 4 enrolling_by_invitation NCT05471960
Neuroplasticity in RBD No drug interventions basic_science Not Available recruiting NCT02789592
Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease treatment 2 unknown_status NCT03671772
Progression of Prodromal Markers of α-synucleinopathy Neurodegeneration in the FDRs of Patients With RBD No drug interventions Not Available Not Available completed NCT05611372
Efficacy and Safety of Rasagiline in Prodromal Parkinson's Disease treatment 2 / 3 not_yet_recruiting NCT05353881
Prodromal Markers in Recurrent Dream Enactment Behaviors Without REM Sleep Without Atonia No drug interventions Not Available Not Available recruiting NCT04152655
A Study of Efficacy and Safety of Idebenone vs. Placebo in Prodromal Parkinson Disease treatment 2 / 3 unknown_status NCT02836743
Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study treatment 4 unknown_status NCT05262543
PREdictive Risk Factors of Conversion Into Idiopathic RBD. Italian Study No drug interventions Not Available Not Available recruiting NCT06270290
The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls No drug interventions Not Available Not Available recruiting NCT06329453
Intestinal Immunity in Neurologic Disease No drug interventions Not Available Not Available recruiting NCT03353207
Striatal Dopamine Transmission in Individuals With Isolated Rapid Eye Movement Sleep With Atonia: a Search for Precursor Biomarker for Neurodegeneration No drug interventions Not Available Not Available completed NCT03288909
Ultra High Field Magnetic Resonance Imaging as a Biomarker for Premotor Parkinson's Disease No drug interventions Not Available Not Available unknown_status NCT01799915
Natural History Study of Synucleinopathies No drug interventions Not Available Not Available recruiting NCT06193252
Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands No drug interventions prevention Not Available recruiting NCT03255642
Efficacy and Safety of Melatonin and Clonazepam for IRBD treatment Not Available completed NCT04071899
French Validation of a Severity Scale in REM Sleep Behavior Disorder (SEV-TCSP) No drug interventions Not Available Not Available unknown_status NCT05256836
Effects of Tablet Computer-based Cognitive Training in Patients With Idiopathic REM Sleep Behavior Disorder No drug interventions treatment Not Available suspended NCT01401413
Study to Determine Whether Ramelteon Helps People With REM Sleep Behavior Disorder treatment 4 completed NCT02824341
Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder No drug interventions diagnostic Not Available completed NCT02708186
Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD) treatment 2 completed NCT04006925
Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate treatment 4 completed NCT05826457
North American Prodromal Synucleinopathy Consortium Stage 2 No drug interventions Not Available Not Available recruiting NCT03645226
Gut Microbiota Across Early Stages of Synucleinopathy: From High-risk Relatives, REM Sleep Behavior Disorder to Early Parkinson's Disease No drug interventions Not Available Not Available completed NCT03675282
Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls No drug interventions other 1 / 2 completed NCT03660982
Familial Aggregation and Biomarkers in REM Sleep Behaviour Disorder. No drug interventions Not Available Not Available unknown_status NCT02871427
Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder treatment 2 terminated NCT03072940
Brain Imaging in the Idiopathic REM Sleep Behavior Disorder (ALICE) No drug interventions Not Available Not Available completed NCT03623672
North American Prodromal Synucleinopathy Consortium No drug interventions Not Available Not Available unknown_status NCT04218968
Cardiac Changes in Early Parkinson's Disease: A Follow up Study treatment 2 enrolling_by_invitation NCT03376568
Investigation of Clinical Feature and Brain Function in Narcoleptic Patients No drug interventions Not Available Not Available unknown_status NCT05353868
Gut Microbiota in the Progression of Alpha-synucleinopathies No drug interventions Not Available Not Available recruiting NCT01547481
MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder. No drug interventions Not Available Not Available completed NCT02312908
Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism treatment 2 completed NCT03047408
Evolution of RBD in PD No drug interventions prevention Not Available unknown_status