Mild pain (DBCOND0117805)

Identifiers

Synonyms

Mild Pain / Mild Pain NOS / Mild pain (finding)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Acetaminophen	An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Cytochrome P450 1A2enzyme Cytochrome P450 2E1enzyme ATP-dependent translocase ABCB1transporter Cytochrome P450 2D6enzyme Cytochrome P450 2A6enzyme Cytochrome P450 3A4enzyme UDP-glucuronosyltransferase 1A1enzyme UDP-glucuronosyltransferase 1-6enzyme UDP-glucuronosyltransferase 1A9enzyme UDP-glucuronosyltransferase 2B15enzyme Sulfotransferase 1A1enzyme Sulfotransferase 1A3enzyme Arylamine N-acetyltransferase 2enzyme Prostaglandin E synthase 3target Transient receptor potential cation channel subfamily V member 1target Albumincarrier Fatty-acid amide hydrolase 1enzyme Glutathione S-transferase Penzyme Glutathione S-transferase Mu 1enzyme Sodium-dependent noradrenaline transportertarget Sodium-dependent serotonin transportertarget
Choline magnesium trisalicylate	Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target
Clove oil	Clove oil is primarily indicated in conditions like colic, flatulence, and toothache .	Vascular cell adhesion protein 1target C-X-C motif chemokine 10target Collagen alpha-1(I) chaintarget Granulocyte-macrophage colony-stimulating factor receptor subunit alphatarget
Codeine	An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.	Mu-type opioid receptortarget Delta-type opioid receptortarget Kappa-type opioid receptortarget Cytochrome P450 2D6enzyme Cytochrome P450 3A4enzyme Solute carrier family 22 member 1transporter UDP-glucuronosyltransferase 2B7enzyme UDP-glucuronosyltransferase 2B4enzyme
Diflunisal	An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Transthyretincarrier Albumincarrier Solute carrier family 22 member 6transporter UDP-glucuronosyltransferase 1A8enzyme UDP-glucuronosyltransferase 1A9enzyme
Fenoprofen	An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Albumincarrier Peroxisome proliferator-activated receptor alphatarget Peroxisome proliferator-activated receptor gammatarget
Ibuprofen	An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Cytochrome P450 2C9enzyme Albumincarrier ATP-binding cassette sub-family C member 4transporter Multidrug resistance-associated protein 1transporter Solute carrier organic anion transporter family member 1A2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier organic anion transporter family member 2B1transporter ATP-dependent translocase ABCB1transporter UDP-glucuronosyltransferase 1A3enzyme UDP-glucuronosyltransferase 1A9enzyme UDP-glucuronosyltransferase 2B4enzyme UDP-glucuronosyltransferase 2B7enzyme Cytochrome P450 2C8enzyme Cytochrome P450 2C19enzyme Apoptosis regulator Bcl-2target Thrombomodulintarget Fatty acid-binding protein, intestinaltarget Peroxisome proliferator-activated receptor gammatarget Cystic fibrosis transmembrane conductance regulatortarget Peroxisome proliferator-activated receptor alphatarget Platelet glycoprotein Ib alpha chaintarget Protein S100-A7target Alpha-methylacyl-CoA racemaseenzyme Cytochrome P450 3A4enzyme C-X-C chemokine receptor type 1target C-X-C chemokine receptor type 2target Interleukin-8target
Ketoprofen	An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target C-X-C chemokine receptor type 1target Albumincarrier ATP-binding cassette sub-family C member 4transporter Solute carrier organic anion transporter family member 1A2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier family 22 member 7transporter Cytochrome P450 2C9enzyme Cytochrome P450 2C8enzyme UDP-glucuronosyltransferase 1A1enzyme
Levomenthol	An organic compound used to treat mild to moderate muscle and joint pain.	Transient receptor potential cation channel subfamily A member 1target Transient receptor potential cation channel subfamily M member 8target Transient receptor potential cation channel subfamily V member 3target Kappa-type opioid receptortarget Voltage-dependent L-type calcium channeltarget Cytochrome P450 3A4enzyme
Meclofenamic acid	An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.	Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Polyunsaturated fatty acid 5-lipoxygenasetarget Solute carrier family 22 member 6transporter Solute carrier organic anion transporter family member 1C1transporter Potassium voltage-gated channel subfamily KQT member 2target Potassium voltage-gated channel subfamily KQT member 3target Thyroxine-binding globulincarrier
Mefenamic acid	An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.	Prostaglandin G/H synthase 2target Prostaglandin G/H synthase 1target Cytochrome P450 2C9enzyme Cytochrome P450 2C8enzyme Albumincarrier UDP-glucuronosyltransferase 1A9enzyme Cytochrome P450 1A2enzyme UDP-glucuronosyltransferase 2B7enzyme
Orphenadrine	A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.	Glutamate receptor ionotropic, NMDA 1target Glutamate receptor ionotropic, NMDA 2Dtarget Glutamate receptor ionotropic, NMDA 3Btarget Glutamate receptor ionotropic, NMDA 3Atarget Histamine H1 receptortarget Cytochrome P450 2B6enzyme Cytochrome P450 2E1enzyme Cytochrome P450 3A4enzyme Sodium-dependent noradrenaline transportertarget Sodium channel protein type 10 subunit alphatarget Cytochrome P450 1A2enzyme Cytochrome P450 2D6enzyme Albumincarrier
Pentazocine	An analgesic used to treat moderate to severe pain.	Mu-type opioid receptortarget Kappa-type opioid receptortarget Sigma non-opioid intracellular receptor 1target ATP-dependent translocase ABCB1transporter
Peppermint oil	An ingredient used in a variety of natural health products and is not an approved medication.	Cytochrome P450 1A2enzyme Cytochrome P450 3A4enzyme
Salicylamide	Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin....	No drug targets

Clinical Trials

Not Available