Androstanes
- Name
- Androstanes
- Accession Number
- DBCAT000981
- Description
The family of steroids from which the androgens are derived.
- Drugs
Drug Drug Description 1-Testosterone 1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. 16-Bromoepiandrosterone Investigated for use/treatment in cystic fibrosis, HIV infection, hepatitis (viral, B), and malaria. 19-norandrostenedione The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated. 4-Hydroxytestosterone 4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by... 5-androstenedione 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... 5alpha-androstane-3beta,17alpha-diol 5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion. Abiraterone An antiandrogen used in the treatment of metastatic castration-resistant prostate cancer and metastatic high-risk castration-sensitive prostate cancer. Afimoxifene For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring. Amafolone Amafolone is a small molecule drug. Amafolone has a monoisotopic molecular weight of 305.24 Da. Androstenediol Androstenediol is an intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted... Androstenedione A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as... Apoptone Investigated for use/treatment in cancer/tumors (unspecified). Atamestane Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Azastene Azastene is a small molecule drug. Azastene has a monoisotopic molecular weight of 355.25 Da. Bezisterim For the treatment of rheumatoid arthritis and type 2 diabetes. Bolasterone Not Available Boldenone Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through... Boldenone undecylenate Not Annotated Boldione Not Available Calusterone An anabolic steroid which can theoretically aid in restauration and buildup of certain tissues, especially muscle. It is similar to synthetic testosterone and is still in early investigation. It was... Clostebol Not Available Clostebol acetate A steroid combined with neomycin in topical formulations for the treatment of minor skin wounds. Drospirenone A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. Drostanolone Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy. Drostanolone propionate For use in females, for palliation of androgenresponsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal. Epitestosterone Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone... Epitiostanol Epitiostanol is a small molecule drug. Epitiostanol has a monoisotopic molecular weight of 306.2 Da. Epristeride Epristeride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Epristeride is a androgen/anabolic steroid. Epristeride has a monoisotopic molecular weight of... Exemestane An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. Finasteride An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. Fluasterone Investigated for use/treatment in psoriasis and psoriatic disorders, hyperlipidemia, metabolic disease, cancer/tumors (unspecified), and obesity. Fluoxymesterone A synthetic androgenic anabolic steroid that used in the treatment of hypogonadism and delayed puberty in males, as well as breast neoplasms in women. Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Fluticasone furoate An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Formebolone No approved indications. Studied experimentally as a treatment for non-pituitary growth retardation. Formestane For the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Furazabol Not Available Galeterone Galeterone has been used in trials studying the treatment of Prostate Cancer. HE-2200 Investigated for use/treatment in adverse effects (chemotherapy), hyperlipidemia, autoimmune diseases, and hepatitis (viral, B). Istaroxime Investigated for use/treatment in heart disease. Loteprednol A corticosteroid indicated in the treatment of pain and inflammation after cataract surgery. Loteprednol etabonate A corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery. Mebolazine Mebolazine is a small molecule drug. Mebolazine has a monoisotopic molecular weight of 632.53 Da. Mepitiostane Mepitiostane is a small molecule drug. Mepitiostane has a monoisotopic molecular weight of 404.27 Da. Mesterolone An anabolic steroid indicated in the treatment of low testosterone, hypogonadism, oligozoospermia, and Leydig cell failure. Metandienone An anabolic steroid indicated for appetite stimulation in patients with anorexia. Metenolone An anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes. Methylhexaneamine Not Annotated Methyltestosterone A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females. Minamestane Minamestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Minamestane is a aromatase inhibitor. Minamestane has a monoisotopic molecular weight of... Nordinone Nordinone is a small molecule drug. Nordinone has a monoisotopic molecular weight of 300.21 Da. Oxandrolone An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. Oxymetholone An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. Pancuronium A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Plomestane Plomestane is a small molecule drug. The usage of the INN stem '-mestane' in the name indicates that Plomestane is a aromatase inhibitor. Plomestane has a monoisotopic molecular weight of... Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Prasterone enantate An estrogen indicated for hormone replacement therapy in postmenopausal women. Prasterone sulfate Investigated for use/treatment in asthma and burns and burn infections. Quinbolone Not Annotated Rapacuronium A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures. Rocuronium A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery. Rostafuroxin Rostafuroxin has been used in trials studying the treatment of Essential Hypertension. Roxibolone Roxibolone is a small molecule drug. Roxibolone has a monoisotopic molecular weight of 360.19 Da. Stanolone A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... Stanozolol An anabolic steroid used to manage hereditary angioedema. Testolactone A medication used to treat advanced breast cancer. Testosterone A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. Testosterone cypionate An androgen used to treat low or absent testosterone. Testosterone decanoate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone enantate benzilic acid hydrazone Not Annotated Testosterone enanthate An androgen used to treat low or absent testosterone. Testosterone isocaproate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone phenylpropionate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone propionate A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. Testosterone succinate Not Available Testosterone undecanoate An androgen indicated for testosterone replacement therapy in adult males with primary hypogonadism and hypogonadotropic hypogonadism. Tiomesterone Tiomesterone is a small molecule drug. The usage of the INN stem '-terone' in the name indicates that Tiomesterone is a antiandrogen. Tiomesterone has a monoisotopic molecular weight of 450.19... Tipredane Tipredane is a small molecule drug. Tipredane has a monoisotopic molecular weight of 410.17 Da. Trilostane Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Turosteride Turosteride is a small molecule drug. The usage of the INN stem '-steride' in the name indicates that Turosteride is a androgen/anabolic steroid. Turosteride has a monoisotopic molecular weight of... Vecuronium A nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures. Wortmannin Wortmannin is a steroid metabolite of Penicillium funiculosum and Talaromyces wortmannii fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks). - Drugs & Drug Targets