- Testosterone Congeners
- Accession Number
- DBCAT001014 (DBCAT001357, DBCAT003190)
Steroidal compounds related to TESTOSTERONE, the major mammalian male sex hormone. Testosterone congeners include important testosterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with androgenic activities.
- ATC Classification
Drug Drug Description Testosterone A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. Nandrolone phenpropionate For the treatment of refractory deficient red cell production anemias, breast carcinoma, hereditary angioedema, antithrombin III deficiency, fibrinogen excess, growth failure and Turner's syndrome. It is also indicated in the... Trilostane Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Testosterone propionate A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. 19-norandrostenedione The claim that supplemental 19-norandrostenedione has anabolic effects is unsubstantiated. 5-androstenedione 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... Bolasterone Not Available 1-Testosterone 1-Testosterone is an anabolic steroid that differs from testosterone by having a 1,2-double bond instead of 4,5-double bond in its A ring. 4-Hydroxytestosterone 4-Hydroxytestosterone is testosterone substituted with a hydroxy group on the fourth carbon atom. It is an anabolic steroid with no therapeutic indications, which is prohibited from use in sports by... Clostebol Not Available Androstenediol Androstenediol is an intermediate in testosterone biosynthesis, found in the testis or the adrenal glands. Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted... Androstenedione A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as... Boldenone Boldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through... Bolandiol Not Available Calusterone An anabolic steroid which can theoretically aid in restauration and buildup of certain tissues, especially muscle. It is similar to synthetic testosterone and is still in early investigation. It was... Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Stanolone A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... 16-Bromoepiandrosterone Investigated for use/treatment in cystic fibrosis, HIV infection, hepatitis (viral, B), and malaria. Prasterone sulfate Investigated for use/treatment in asthma and burns and burn infections. Trestolone Investigated for use/treatment in contraception and male hormonal deficiencies/abnormalities. Fluasterone Investigated for use/treatment in psoriasis and psoriatic disorders, hyperlipidemia, metabolic disease, cancer/tumors (unspecified), and obesity. Methyltestosterone A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females. Testosterone succinate Not Available Nandrolone decanoate An anabolic steroid indicated for the management of the anemia of renal insufficiency by increasing hemoglobin and red cell mass. Formestane For the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Dienogest An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol. Mibolerone Mibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone. Atamestane Atamestane has been used in trials studying the treatment of Breast Cancer, Breast Neoplasms, and Neoplasms, Hormone-Dependent. Nandrolone An anabolic steroid indicated to increase bone density and muscle mass in patients with osteoporosis. Mesterolone An anabolic steroid indicated in the treatment of low testosterone, hypogonadism, oligozoospermia, and Leydig cell failure. Metenolone An anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes. Testosterone cypionate An androgen used to treat low or absent testosterone. Testosterone enanthate An androgen used to treat low or absent testosterone. Testosterone undecanoate An androgen used to treat low or absent testosterone. Testosterone enantate benzilic acid hydrazone Not Annotated Trestolone acetate Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate... Epitestosterone Epitestosterone is the 17-alpha isomer of testosterone, derived from pregnenolone via the delta5-steroid pathway, and via 5-androstene-3-beta,17-alpha-diol. Epitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone... Clostebol acetate A steroid combined with neomycin in topical formulations for the treatment of minor skin wounds. Testosterone decanoate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone isocaproate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Testosterone phenylpropionate A steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. Prasterone enantate An estrogen indicated for hormone replacement therapy in postmenopausal women.
- Drugs & Drug Targets