(S)-Rolipram

DB03606ExperimentalSmall molecule

A phosphodiesterase inhibitor with antidepressant properties. [PubChem].

Mechanism: Pharmacologically active on 3',5'-cyclic-AMP phosphodiesterase 4B
Curator reviewed
Formula / weight: C₁₆H₂₁NO₃ · 275.348 g/mol (avg)
Also known as: S-rolipram

Resolves to

Compound

Clinical / RWD

Structure

InChIKeyHJORMJIFDVBMOB-GFCCVEGCSA-NSMILES[H][C@@]1(CNC(=O)C1)C1=CC=C(OC)C(OC2CCCC2)=C1

Targets

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with (S)-Rolipram, and which of those have an active Phase 3 trial?

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