Alimentary Tract and Metabolism
- Alimentary Tract and Metabolism
- Accession Number
- ATC Classification
Drug Drug Description Selenium An ingredient found in a variety of supplements and vitamins. Insulin human A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. Insulin lispro A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. Insulin glargine A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. Imiglucerase A form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. Insulin pork A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. Pancrelipase A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. Alglucerase A form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. Laronidase A form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase. Agalsidase beta A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. Pyridoxal phosphate A vitamin available in many formulations to correct vitamin B6 deficiency. Ademetionine S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... Biotin A B-complex vitamin found in many multivitamin products. L-Glutamine An amino acid commonly found as a component in total parenteral nutrition. Riboflavin A vitamin used to correct vitamin B2 deficiency. Glutamic acid An amino acid commonly found as a component in total parenteral nutrition. Calcifediol An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. Thiamine A vitamin used to correct vitamin B1 deficiency. Ergocalciferol A vitamin found in many supplement products. Pyridoxine A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy. Lipoic acid For nutritional supplementation, also for treating dietary shortage or imbalance. Phentermine A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. Troglitazone For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. Pantoprazole A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. Oxyphenonium For the treatment of visceral spasms Glimepiride A sulfonylurea drug used to treat type 2 diabetes mellitus. Acarbose An alpha-glucosidase inhibitor used in adjunctly with diet and exercise for the management of glycemic control in patients with type 2 diabetes mellitus. Calcium glucoheptonate A calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels. Metformin A biguanide antihyperglycemic used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus. It is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS). Omeprazole A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. Nitisinone A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods. Sapropterin A cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). Sucralfate A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence. Palonosetron A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. Oxyphencyclimine A drug used to treat smooth muscle spasticity. Rosiglitazone A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. Acetohexamide Used in the management of diabetes mellitus type 2 (adult-onset). Miglustat A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. Hyoscyamine An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. Lansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Dronabinol A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Nabilone A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Miglitol An oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates. Cimetidine A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. Tridihexethyl Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Fenfluramine Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. Mazindol A sympathomimetic used to treat obesity in combination with lifestyle modifications. Lactulose A disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. Levocarnitine A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. Nizatidine An H2 receptor antagonist used to treat GERD and a variety of ulcers. Cisapride A medication used to treat heartburn associated with GERD. Oxandrolone An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. Prednisone A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. Pirenzepine An antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Chlorpropamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Aprepitant A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. Amphotericin B An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. Homatropine methylbromide A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Nateglinide A meglitinide used to treat non insulin dependent diabetes mellitus. Esomeprazole A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. Scopolamine A belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV). Dolasetron An antinauseant and antiemetic used in chemotherapy and postoperatively. Potassium chloride A potassium salt used to treat hypokalemia. Clidinium A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Dicyclomine An antimuscarinic agent used to treat IBS. Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. Tolazamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Cysteamine A cystine depleting agent used to treat the effects of cystinosis. Ranitidine A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis. Granisetron A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. Tinidazole A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. Repaglinide A antihyperglycemic used to improve glycemic control in diabetes. Phenformin For the reatment of type II diabetes mellitus. Famotidine A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. Misoprostol A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers and to terminate pregnancies. Diethylpropion An appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Balsalazide An aminosalicylate used to treat ulcerative colitis. Glyburide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Lubiprostone A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. Glipizide A sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release. Dihydrotachysterol A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. Tegaserod A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. Diphenoxylate An antidiarrheal medication used with atropine to manage diarrhea. Streptomycin An aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Orlistat A reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance. Sibutramine A norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". Gliclazide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Pioglitazone A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. Domperidone A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. Dexfenfluramine For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet Clarithromycin A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. Rifaximin A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. Metoclopramide An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. Olsalazine An anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis. Gliquidone A sulfonylurea drug used in the management of diabetes mellitus type 2. Mitiglinide For the treatment of type 2 diabetes. Sitagliptin An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. Idursulfase A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. Alglucosidase alfa An acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency. Exenatide A GLP-1 agonist used in the management of type 2 diabetes mellitus. Pramlintide An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. Galsulfase A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. Glisoxepide For the treatment of diabetes mellitus type 2. Insulin aspart A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin detemir A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Insulin glulisine A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. Magnesium oxide A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Paromomycin An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. Alizapride A dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies. Cathine Used to decrease appetite. Ethylestrenol An anabolic steroid with some progestational activity and little androgenic effect. [PubChem] Difenoxin An antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea. Attapulgite A veterinary antidiarrheal agent used to treat non-infectious diarrhea in animals. Kaolin A natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding. Ursodeoxycholic acid A bile acid used for the treatment of primary biliary cirrhosis (PBC). Alverine A smooth muscle relaxant used to relieve abdominal pain associated with gastrointestinal conditions like heartburn, flatulence, and Irritable Bowel Syndrome. Isopropamide A long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions. Pantothenic acid A vitamin B5 found in various nutritional supplements. Carbenoxolone A drug used to symptomatically treat lip sores and mouth ulcers. Tolrestat For the pharmacological control of certain diabetic complications. Cholic Acid A bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. Nicotinamide An ingredient found in a variety of cosmetic products. Pidolic acid There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in... Benzoic acid An antimicrobial food additive. Citric acid An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products. Dantron A drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx. Oxyphenisatin A laxative that undergoes enterohepatic circulation. It may cause jaundice. Phenolphthalein A drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures. Buformin Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of... Mepenzolate A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. Lorcaserin A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. Vildagliptin A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. Voglibose An alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes. Cilansetron For the treatment of symptoms associated with irritable bowel syndrome. Itopride An acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting. Dexlansoprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Obeticholic acid A bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. Rimonabant For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated... Alogliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. Alvimopan An opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis. Dapagliflozin A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. Saxagliptin An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. Oxymetholone An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. Prucalopride A 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation. Casopitant Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). Liraglutide A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. Isometheptene A sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole. Stanozolol An anabolic steroid used to manage hereditary angioedema. Velaglucerase alfa An enzyme replacement therapy used for the long-term treatment of for pediatric and adult patients with type 1 Gaucher disease. Aluminum hydroxide An antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. Calcium carbonate An ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. Drotaverine A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. Betaine A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Sacrosidase An enzyme replacement therapy used for the treatment of congenital sucrase-isomaltase deficiency (CSID). Carglumic acid An analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency. Chenodeoxycholic acid A bile acid used for the treatment of primary biliary cirrhosis. Hexocyclium The World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea. Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Phenylbutyric acid An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. Hymecromone A coumarin derivative that lacks anticoagulant properties but possesses choleretic and biliary antispasmodic activity. Roxatidine acetate For the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also... N-methylnicotinamide N-methylnicotinamide is an experimental drug with no approved indication. Fidaxomicin A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. Taliglucerase alfa A hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease. Linagliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Linaclotide A guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature. Teduglutide A glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support. Canagliflozin A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. Glycerol phenylbutyrate A nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions. Magaldrate An antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Glibornuride Glibornuride is a sulfonylurea-type anti-diabetic drug. Fentonium Fentonium is an atropine derivative. Bromopride A substituted benzamide, closely related to metoclopramide, used as an antiemetic. Bisacodyl A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. Benfluorex Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... Empagliflozin An SGLT2 inhibitor used to manage type 2 diabetes mellitus. Eliglustat A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers. Albiglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Dulaglutide A GLP-1 agonist used to manage type 2 diabetes mellitus. Naloxegol A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Asfotase alfa An enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP). Potassium citrate An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. Bisoxatin For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . Lixisenatide A GLP-1 receptor agonist used for the management of type 2 diabetes mellitus. Picosulfuric acid A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. Cimetropium Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which... Activated charcoal A gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons. Polyethylene glycol A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Sodium fluoride An ingredient of various dental preparations used to support tooth mineralization and the prevention of dental caries. Insulin beef Insulin beef has been discontinued in the US and Canada since 2017. Glycerin It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent. Sodium sulfate An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. Magnesium carbonate An antacid used for symptomatic relief of heartburn, indigestion, and upset stomach. Sodium fluorophosphate A fluoride anticaries agent used to prevent and treat dental cavities. Insulin degludec A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. Mineral oil Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive... Selenic acid An ingredient found in a variety of supplements and vitamins. Docusate A medication used to treat constipation associated with dry, hard stools, or opioid induced constipation. Stannous fluoride A medication used to treat dental hypersensitivity, produce enamel, prevent gingivitis and cavities, and prevent periodontal infections. Calcium citrate An ingredient found in a variety of supplements and vitamins. Potassium bicarbonate An ingredient used as an antacid or to treat hypokalemia. Magnesium citrate A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. Castor oil An ingredient used in a variety of natural health products. Calcium gluconate An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning. Selenious acid An ingredient found in supplements, vitamins, parenteral nutrition, and dandruff shampoo. Opium A medication used to treat moderate to severe pain. Oxyquinoline A medication used in combination with other medications to restore vaginal pH. Pectin Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary... Pantethine A naturally occurring compound derived from panthothenic acid. It acts as an intermediate in endogenous coenzyme A synthesis and is used as a dietary supplement to treat hypertriglyceridemia. Methylcellulose A compound used as a bulk forming laxative and is not an approved medication. Zinc gluconate An ingredient found in a variety of supplements and vitamins. Tocopherol Tocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and... Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... Calcium Phosphate A compound used in supplements and antacids. Sennosides A laxative used to treat constipation. Chlorobutanol No approved therapeutic indications on its own. Sebelipase alfa A recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency. Domiphen Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions. Tocofersolan A derivative of alpha tocopherol used to treat vitamin E deficiencies. Racecadotril An anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea. Tropisetron A 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting. Benfotiamine A derivative of thiamine thought to be useful in the management of diabetic neuropathy, although evidence is lacking. Gefarnate Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. Gemigliptin A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. Mebeverine An antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses. Lafutidine Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). Norethandrolone Norethandrolone is under investigation in clinical trial NCT00700544 (Treatment Outcome in Elderly Patients). Lactitol An orally administered osmotic laxative used to treat chronic idiopathic constipation. Phloroglucinol A spasmolytic agent to treat colic, as well as spastic pain of the digestive and biliary tracts. Fenoverine A phenothiazine based anti-spasmodic agent indicated in the treatment of irritable bowel syndrome. Tiropramide A medication indicated in the treatment of spastic pain of the gastrointestinal system. Calcium glubionate anhydrous A calcium salt indicated in the treatment of hypocalcemia, hyperkalemia, lead poisoning, and as an adjunct in the treatment of exudative skin conditions. Sodium lauryl sulfoacetate A laxative indicated in the treatment of constipation and bowel preparation for rectal endoscopy. Nandrolone An anabolic steroid indicated to increase bone density and muscle mass in patients with osteoporosis. Inositol An ingredient found in a variety of nutritional products. Oxabolone cipionate Used as a performance enhancing drug illicitly in athletes. Pepsin A protease indicated in the treatment of digestive disorders. Piprozolin Not Annotated Arginine glutamate Two amino acids indicated in the treatment of hyperammonemia and in combination for total parenteral nutrition. Bismuth subnitrate A medication used as an antacid. Calcium lactate An ingredient found in a variety of nutritional products. Perboric acid In the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid... Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Magnesium silicate Magnesium silicate is used to absorb moisture, prevent caking, and to improve the feel of a product. In the pharmaceutical companies, it is used as a dietary supplement, as part... Methylmethionine chloride Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also... Prifinium Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome . Acetarsol An anti infective used to treat a wide variety of infections in the body. Idanpramine Not Annotated Aluminium acetoacetate Aluminium acetoacetate is an aluminum containing antacid. Etilamfetamine Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this... Olaflur A fluoride treatment for patients at risk of dental caries, sensitive teeth, or enamel decalcification. Sulglicotide Not Annotated Trepibutone Not Annotated Hydrotalcite An antacid indicated in the treatment of heartburn and excess gastric acid. Nifurzide Not Annotated Piperidolate Not Annotated Magnesium aspartate Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts... Trimethyldiphenylpropylamine Not Annotated Calcium lactate gluconate A calcium salt indicated in the treatment of rickets, osteomalacia, and the treatment and prevention of calcium deficiency Hydrochloric acid A strong acid used to adjust the pH of injections and ophthalmic solutions. Benzilone Not Annotated Difemerine Not Annotated Adrenalone Not Annotated Carbutamide Not Annotated Sulbutiamine A thiamine derivative indicated in the treatment of asthenia. Troxipide Not Annotated Proglumide Not Annotated Fenpiprane Not Annotated Citiolone Not Annotated Guar gum Not Annotated Diisopromine Not Annotated Quinbolone Not Annotated Magnesium peroxide Not Annotated Cyclobutyrol Not Annotated Valethamate An anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Poldine Not Annotated Clebopride A dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy. Alginic acid Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress . Cerium oxalate Not Annotated Pentaerithrityl Not Annotated Nicofetamide Not Annotated Broxyquinoline Not Annotated Bevonium Not Annotated Clobenzorex Not Annotated Benzoxonium An antiseptic indicated in skin disinfection and prevention of infections. Succinylsulfathiazole Not Annotated Rociverine An antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms. Metandienone An anabolic steroid indicated for appetite stimulation in patients with anorexia. Calcium pangamate Not Annotated Metopimazine Not Annotated Zolimidine Not Annotated Almasilate Almasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is... Potassium gluconate A potassium supplement indicated in the treatment and prevention of hypokalemia. Aluminium glycinate A medication indicated to treat heartburn, indigestion, acid reflux, ulcers, and gas. Acetoxolone Not Annotated Aloglutamol Aloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro. Montmorillonite A purified clay indicated in the treatment of intestinal pain and diarrhea. Tiemonium iodide Not Annotated Dimethylaminopropionylphenothiazine Not Annotated Metahexamide Not Annotated Dihexyverine Not Annotated Penthienate Not Annotated Tibezonium iodide Not Annotated Sodium tartrate It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to... Metenolone An anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes. Diphemanil Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). Sulfaguanidine Not Annotated Camylofin Not Annotated Tidiacic arginine Not Annotated Magnesium gluconate A mineral supplement used to treat or prevent hypomagnesemia. Glycyrrhizic acid Glycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to... Fenpiverinium An anticholinergic agent indicated in the treatment of smooth muscle spasms. Niperotidine Not Annotated Tilactase A beta-D-galactosidase use to treat lactose intolerance. Dexrabeprazole A proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers. Emetonium iodide Not Annotated Magnesium orotate Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat... Chlorbenzoxamine Not Annotated Calcium levulinate This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and... Epomediol Not Annotated Proxazole Not Annotated Enprostil Not Annotated Calcium silicate Not Annotated Methylatropine Not Annotated Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. Pipenzolate An antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia. Timepidium Not Annotated Mefenorex Not Annotated Anethole trithione A medication used to treat dry mouth associated with medication or radiotherapy of the head and neck. Nifuroxazide An antibiotic indicated in the treatment of susceptible gastrointestinal infections. Becaplermin A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. Ascorbic acid A vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron. Calcitriol An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Vitamin A A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. Cholecalciferol A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Doxycycline A tetracycline antibiotic used to treat a wide variety of bacterial infections. Calcium acetate A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Vancomycin A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. Nystatin A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species. Magnesium sulfate A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. Naltrexone A narcotic antagonist used in opioid overdose. Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Mannitol A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. Tetracycline An antibiotic used to treat a wide variety of susceptible infections. Sulfasalazine A salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Colistin A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. Natamycin A macrolide antifungal used to treat fungal infections of the eye. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Chlorhexidine An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. Metronidazole A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. Neomycin An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. Minocycline A tetracycline analog used to treat a wide variety of infections in the body. Amlexanox Used as a paste in the mouth to treat aphthous ulcers (canker sores). Amoxicillin A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Levofloxacin A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. Calcium chloride An ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate. Kanamycin An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Calcium A mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency. Alfacalcidol A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia. Iron An essential element commonly used for the treatment of patients with documented iron deficiency. Sorbitol A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. Prasterone A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. Stanolone A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... Beta carotene A vitamin A precursor found in various nutritional supplements and health products. Hexetidine An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa. Benzydamine A locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy. Tixocortol A corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis. Chlortetracycline The first tetracycline antibiotic most commonly used for veterinary purposes. Magnesium hydroxide An inorganic compound used as a laxative and antacid. Sodium chloride An ingredient found in a variety of nutritional products as a source of electrolytes and water. Zinc sulfate A drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. Dexpanthenol An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). Magnesium chloride An ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies. Hydrogen peroxide A compound used as a disinfectant and sterilizer. Emepronium Not Annotated Mepartricin A medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis. Zinc acetate A medication used to treat zinc deficiency. Magnesium levulinate A supplement to treat magnesium deficiency. Magnesium lactate Not Available Aluminium phosphate Not Available Plantago ovata seed A plant extract indicated in the treatment of occasional constipation. Loperamide oxide Not Annotated Calcium polycarbophil A bulk forming laxative used to treat constipation. Ornithine An amino acid commonly found as a component in total parenteral nutrition. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Naloxone An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. Crofelemer An antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy. Migalastat An alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant. Triethylenetetramine A copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate. Cinitapride A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying. Metreleptin A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. Uridine triacetate A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. Rolapitant A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy. Rebamipide A gastroprotective agent used in combination with other similar therapies (e.g. proton pump inhibitors) to treat gastritis and protect the gastric mucosa. Naldemedine An opioid antagonist used to to treat opioid-induced constipation. Ipragliflozin Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. Ertugliflozin A SGLT2 inhibitor used to treat type 2 diabetes mellitus. Vestronidase alfa A recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII. Velmanase alfa A recombinant human lysosomal alpha-mannosidase used to treat non-neurological symptoms of mild to moderate alpha-mannosidosis. Evogliptin Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. Plecanatide A laxative used to treat chronic idiopathic constipation and IBS with constipation. Cerliponase alfa An enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency. Semaglutide A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. Telotristat A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. Polymyxin B A polymyxin antibiotic used to treat a wide variety of infections in the body. Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. Karaya gum An extract from Karaya gum used in allergy testing. Mosapride A prokinetic 5-HT4 receptor agonist used to stimulate gastric motility. Vonoprazan A potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication. Rifamycin An antibacterial used to treat traveler's diarrhea. Sotagliflozin An orally administered dual SGLT1/2 inhibitor used alongside insulin to improve glycemic control in patients with type 1 diabetes mellitus. Pegvaliase An enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment. Agalsidase alfa A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. Pitofenone A medication used in the treatment of spastic pain caused by menstrual cramps, the digestive system, and the urinary tract. Idursulfase beta Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase). Bismuth subcitrate potassium A colloid used for the treatment of peptic ulcer and gastro-esophageal reflux disease (GERD). Silibinin A flavonolignan with hepatoprotective effects used to treat toxic liver damage and as an adjunct in the management of chronic conditions such as cirrhosis and hepatitis. Sodium phosphate, monobasic A source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake. Yeast An extract from Yeast used in allergy testing. Rifabutin An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. Lonafarnib A potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies. Lobeglitazone Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... Phenylacetic acid An agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle. Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Triheptanoin Triheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders. Setmelanotide Setmelanotide is indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome. Tenapanor An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). Teneligliptin Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus. Luseogliflozin An SGLT2 inhibitor used to manage type 2 diabetes mellitus. Imeglimin Imeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus. Pegunigalsidase alfa A recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease. Givosiran A 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria. Beinaglutide Beinaglutide is under investigation in clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus). Lumasiran Lumasiran is an interfering RNA that silences hydroxyacid oxidase 1 for the treatment of primary hypoxaluria type 1. Avalglucosidase alfa A lysosomal glycogen-specific enzyme that is used to treat patients one year of age and older with late-onset Pompe disease, or lysosomal acid alpha-glucosidase (GAA) deficiency. Maralixibat An ileal bile acid transporter inhibitor indicated to treat cholestatic pruritus in patients with Alagille syndrome. Odevixibat An ileal sodium/bile acid cotransporter inhibitor indicated in the treatment of pruritus in patients with progressive familial intrahepatic cholestasis. Metadoxine A medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy. Fosdenopterin An exogenous form of cyclic pyranopterin monophosphate (cPMP) used as a replacement substrate in patients with molybdenum cofactor deficiency (MoCD) type A. Tegoprazan Tegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases.[A234215, A234220] This drug is a potent and high-selective potassium-competitive acid blocker... Atidarsagene autotemcel A gene therapy comprising autologous CD34+ enriched stem cells encoding the human arylsulfatase A (ARSA) gene used to treat metachromatic leukodystrophy (MLD). Topiramate An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. Oxytetracycline A tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections. Omega-3 fatty acids An ingredient found in a variety of supplements and vitamins. Acotiamide Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia. Elobixibat Elobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation. Octenidine An antiseptic agent used topically, on mucous membranes, and prior to surgery. Olipudase alfa A recombinant human acid sphingomyelinase used to treat Acid Sphingomyelinase Deficiency (ASMD) in children and adults. Pegzilarginase Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency). Dorzagliatin Dorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM). Tirzepatide A dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise. Teprenone A medication indicated in the treatment of acute gastroenteritis, exacerbations of gastric inflammation, and gastric ulcers. Cipaglucosidase alfa Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in... Elivaldogene autotemcel A gene replacement therapy for treating early cerebral adrenoleukodystrophy comprising autologous hematopoietic stem cells transduced with a viral vector encoding ABCD1 complementary DNA for human adrenoleukodystrophy protein.
- Drugs & Drug Targets