| Selenium | An ingredient found in a variety of supplements and vitamins. |
| Insulin human | A recombinant form of human insulin used to control hyperglycemia in diabetes mellitus. |
| Insulin lispro | A modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus. |
| Insulin glargine | A modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus. |
| Imiglucerase | A form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. |
| Insulin pork | A purified form of porcine insulin used to control hyperglycemia in diabetes mellitus. |
| Pancrelipase | A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. |
| Alglucerase | A form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease. |
| Laronidase | A form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase. |
| Agalsidase beta | A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. |
| Pyridoxal phosphate | A vitamin available in many formulations to correct vitamin B6 deficiency. |
| Ademetionine | S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as... |
| Biotin | A B-complex vitamin found in many multivitamin products. |
| L-Glutamine | An amino acid commonly found as a component in total parenteral nutrition. |
| Riboflavin | A vitamin used to correct vitamin B2 deficiency. |
| Glutamic acid | An amino acid commonly found as a component in total parenteral nutrition. |
| Calcifediol | An active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients. |
| Thiamine | A vitamin used to correct vitamin B1 deficiency. |
| Ergocalciferol | A vitamin found in many supplement products. |
| Pyridoxine | A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy. |
| Lipoic acid | For nutritional supplementation, also for treating dietary shortage or imbalance. |
| Phentermine | A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. |
| Troglitazone | For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. |
| Pantoprazole | A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. |
| Oxyphenonium | For the treatment of visceral spasms |
| Glimepiride | A sulfonylurea drug used to treat type 2 diabetes mellitus. |
| Acarbose | An alpha-glucosidase inhibitor used in conjunction with diet and exercise for management of type II diabetes mellitus. |
| Calcium glucoheptonate | A calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels. |
| Metformin | A biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS). |
| Omeprazole | A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. |
| Nitisinone | A hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1), which causes intolerance to tyrosine containing foods. |
| Sapropterin | A cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU). |
| Sucralfate | A gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence. |
| Palonosetron | A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. |
| Oxyphencyclimine | For the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders. |
| Rosiglitazone | A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. |
| Acetohexamide | Used in the management of diabetes mellitus type 2 (adult-onset). |
| Miglustat | A glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement. |
| Hyoscyamine | For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease... |
| Lansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Dronabinol | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
| Nabilone | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
| Miglitol | An oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates. |
| Cimetidine | A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. |
| Tridihexethyl | Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus |
| Atropine | A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. |
| Fenfluramine | Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. |
| Mazindol | A sympathomimetic used to treat obesity in combination with lifestyle modifications. |
| Lactulose | A disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy. |
| Levocarnitine | A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. |
| Nizatidine | An H2 receptor antagonist used to treat GERD and a variety of ulcers. |
| Cisapride | A medication used to treat heartburn associated with GERD. |
| Oxandrolone | An androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis. |
| Prednisone | A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. |
| Pirenzepine | An antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. |
| Chlorpropamide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
| Amphotericin B | An antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis. |
| Homatropine methylbromide | A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. |
| Nateglinide | A meglitinide used to treat non insulin dependent diabetes mellitus. |
| Esomeprazole | A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. |
| Scopolamine | An anticholinergic used to treat excessive salivation, colicky abdominal pain, bradycardia, diverticulitis, IBS, and motion sickness. |
| Dolasetron | An antinauseant and antiemetic used in chemotherapy and postoperatively. |
| Potassium chloride | A potassium salt used to treat hypokalemia. |
| Clidinium | A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. |
| Propantheline | An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. |
| Dicyclomine | An antimuscarinic agent used to treat IBS. |
| Loperamide | A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. |
| Tolazamide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Cysteamine | A cystine depleting agent used to treat the effects of cystinosis. |
| Ranitidine | A histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis. |
| Granisetron | A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. |
| Tinidazole | A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. |
| Repaglinide | A antihyperglycemic used to improve glycemic control in diabetes. |
| Phenformin | For the reatment of type II diabetes mellitus. |
| Famotidine | A histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. |
| Misoprostol | A prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers. |
| Diethylpropion | An appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction. |
| Methantheline | For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. |
| Alosetron | A 5-HT3 antagonist used to treat diarrhea-predominant IBS. |
| Glycopyrronium | An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. |
| Balsalazide | An aminosalicylate used to treat ulcerative colitis. |
| Glyburide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Lubiprostone | A prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use. |
| Glipizide | A sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release. |
| Dihydrotachysterol | A synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3. |
| Tegaserod | A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. |
| Diphenoxylate | An antidiarrheal medication used with atropine to manage diarrhea. |
| Streptomycin | An aminoglycoside antibiotic indicated to treat mycobacterium tuberculosis and various non-tuberculosis infections. |
| Orlistat | A reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance. |
| Sibutramine | A norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. |
| Papaverine | An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". |
| Gliclazide | A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Rabeprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Pioglitazone | A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. |
| Domperidone | A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. |
| Dexfenfluramine | For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet |
| Clarithromycin | A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. |
| Rifaximin | A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. |
| Metoclopramide | An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. |
| Olsalazine | An anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis. |
| Gliquidone | Used in the treatment of diabetes mellitus type 2. |
| Mitiglinide | For the treatment of type 2 diabetes. |
| Sitagliptin | An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. |
| Idursulfase | A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. |
| Alglucosidase alfa | An acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency. |
| Exenatide | A GLP-1 agonist used in the management of type 2 diabetes mellitus. |
| Pramlintide | An amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy. |
| Galsulfase | A recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme. |
| Glisoxepide | For the treatment of diabetes mellitus type 2. |
| Insulin aspart | A rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| Insulin detemir | A long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| Insulin glulisine | A short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus. |
| Magnesium oxide | A compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health. |
| Glymidine | Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. |
| Paromomycin | An aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. |
| Alizapride | Alizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. |
| Cathine | Used to decrease appetite. |
| Ethylestrenol | An anabolic steroid with some progestational activity and little androgenic effect. [PubChem] |
| Difenoxin | An antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea. |
| Attapulgite | A veterinary antidiarrheal agent used to treat non-infectious diarrhea in animals. |
| Kaolin | A natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding. |
| Ursodeoxycholic acid | A bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. |
| Alverine | Used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to... |
| Isopropamide | For the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis,... |
| Pantothenic acid | A vitamin B5 found in various nutritional supplements. |
| Carbenoxolone | An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is... |
| Tolrestat | For the pharmacological control of certain diabetic complications. |
| Cholic Acid | A bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. |
| Nicotinamide | An ingredient found in a variety of cosmetic products. |
| Pidolic acid | There is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication.
Although pidolic acid may be sold in... |
| Benzoic acid | An antimicrobial food additive. |
| Citric acid | An anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products. |
| Dantron | Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. |
| Oxyphenisatin | A laxative that undergoes enterohepatic circulation. It may cause jaundice. |
| Phenolphthalein | Used for over a century as a laxative. |
| Buformin | Buformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of... |
| Mepenzolate | A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. |
| Lorcaserin | A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. |
| Vildagliptin | A once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. |
| Voglibose | For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications. |
| Cilansetron | For the treatment of symptoms associated with irritable bowel syndrome. |
| Itopride | Investigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous). |
| Dexlansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Obeticholic acid | A bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. |
| Rimonabant | For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated... |
| Alogliptin | A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Alvimopan | An opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis. |
| Dapagliflozin | A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. |
| Saxagliptin | An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. |
| Oxymetholone | An anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias. |
| Prucalopride | A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST). |
| Casopitant | Investigated for use/treatment in urinary incontinence and adverse effects (chemotherapy). |
| Liraglutide | A GLP-1 analog used in the management of type 2 diabetes mellitus and prevention of cardiovascular complications associated with diabetes. |
| Isometheptene | Isometheptene is a sympathomimetic drug which causes vasoconstriction. It is used for treating migraines and tension headaches. |
| Stanozolol | Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating C1-inhibitor deficient hereditary angioedema. C1-inhibitor is a protease that inhibits the complement system (part of the innate immune system),... |
| Velaglucerase alfa | An enzyme replacement therapy used for the long-term treatment of for pediatric and adult patients with type 1 Gaucher disease. |
| Aluminum hydroxide | An antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. |
| Calcium carbonate | An ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach. |
| Drotaverine | Used in the treatment of functional bowel disorders and alleviating pain in renal colic. |
| Glycine betaine | A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. |
| Sacrosidase | An enzyme replacement therapy used for the treatment of congenital sucrase-isomaltase deficiency (CSID). |
| Carglumic acid | An analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency. |
| Chenodeoxycholic acid | A bile acid used for the treatment of primary biliary cirrhosis. |
| Hexocyclium | The World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea. |
| Methylnaltrexone | A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. |
| Phenylbutyric acid | An agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy. |
| Hymecromone | Not Available |
| Roxatidine acetate | For the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also... |
| N-methylnicotinamide | N-methylnicotinamide is an experimental drug with no approved indication. |
| Fidaxomicin | A macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection. |
| Taliglucerase alfa | A hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease. |
| Linagliptin | A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. |
| Linaclotide | A guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature. |
| Teduglutide | A glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support. |
| Canagliflozin | A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. |
| Glycerol phenylbutyrate | A nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions. |
| Magaldrate | An antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. |
| Glibornuride | Glibornuride is a sulfonylurea-type anti-diabetic drug. |
| Fentonium | Fentonium is an atropine derivative. |
| Bromopride | Bromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the... |
| Bisacodyl | A stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults. |
| Benfluorex | Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended... |
| Empagliflozin | An SGLT2 inhibitor used to manage type 2 diabetes mellitus. |
| Eliglustat | A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers, based on the FDA-approved test. |
| Albiglutide | A GLP-1 agonist used to manage type 2 diabetes mellitus. |
| Dulaglutide | A GLP-1 agonist used to manage type 2 diabetes mellitus. |
| Naloxegol | A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. |
| Elosulfase alfa | A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. |
| Trimebutine | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. |
| Pinaverium | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. |
| Asfotase alfa | An enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP). |
| Potassium citrate | An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. |
| Bisoxatin | For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . |
| Lixisenatide | A GLP-1 receptor agonist used for the management of type 2 diabetes mellitus. |
| Picosulfuric acid | A stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults. |
| Cimetropium | Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which... |
| Activated charcoal | A gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons. |
| Polyethylene glycol | A laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures. |
| Butylscopolamine | An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. |
| Sodium fluoride | An ingredient of various dental preparations used to support tooth mineralization and the prevention of dental caries. |
| Insulin beef | Insulin beef has been discontinued in the US and Canada since 2017. |
| Glycerin | It is used as a solvent, emollient, pharmaceutical agent, and sweetening agent. |
| Sodium sulfate | An agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination. |
| Magnesium carbonate | An antacid used for symptomatic relief of heartburn, indigestion, and upset stomach. |
| Sodium fluorophosphate | A fluoride anticaries agent used to prevent and treat dental cavities. |
| Insulin degludec | A long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus. |
| Mineral oil | Mineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive... |
| Selenic acid | An ingredient found in a variety of supplements and vitamins. |
| Docusate | A medication used to treat constipation associated with dry, hard stools, or opioid induced constipation. |
| Stannous fluoride | A medication used to treat dental hypersensitivity, produce enamel, prevent gingivitis and cavities, and prevent periodontal infections. |
| Calcium citrate | An ingredient found in a variety of supplements and vitamins. |
| Potassium bicarbonate | An ingredient used as an antacid or to treat hypokalemia. |
| Magnesium citrate | A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. |
| Castor oil | An ingredient used in a variety of natural health products. |
| Calcium gluconate | An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning. |
| Selenious acid | An ingredient found in supplements, vitamins, parenteral nutrition, and dandruff shampoo. |
| Opium | A medication used to treat moderate to severe pain. |
| Oxyquinoline | A medication used in combination with other medications to restore vaginal pH. |
| Pectin | Pectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary... |
| Pantethine | Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer... |
| Methylcellulose | A compound used as a bulk forming laxative and is not an approved medication. |
| Zinc gluconate | An ingredient found in a variety of supplements and vitamins. |
| Tocopherol | Tocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and... |
| Methscopolamine | Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... |
| Calcium Phosphate | A compound used in supplements and antacids. |
| Sennosides | A laxative used to treat constipation. |
| Chlorobutanol | No approved therapeutic indications on its own. |
| Sebelipase alfa | A recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency. |
| Domiphen | Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions. |
| Tocofersolan | A derivative of alpha tocopherol used to treat vitamin E deficiencies. |
| Racecadotril | Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and Acute Gastroenteritis. |
| Tropisetron | For the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative. |
| Benfotiamine | Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2. |
| Gefarnate | Gefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease. |
| Moxaverine | Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. |
| Gemigliptin | Gemigliptin is under investigation in Type 2 Diabetes Mellitus. Gemigliptin has been investigated for the treatment of Cancer and Cisplatin Adverse Reaction. |
| Mebeverine | Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms. |
| Lafutidine | Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD). |
| Norethandrolone | Norethandrolone is under investigation in clinical trial NCT00700544 (Treatment Outcome in Elderly Patients). |
| Lactitol | An orally administered osmotic laxative used to treat chronic idiopathic constipation. |
| Phloroglucinol | Phloroglucinol has been used in trials studying the diagnostic of Colonoscopy. |
| Fenoverine | Fenoverine has been used in trials studying the treatment of Irritable Bowel Syndrome. |
| Tiropramide | Tiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome). |
| Calcium glubionate anhydrous | Calcium glubionate is indicated to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain... |
| Sodium lauryl sulfoacetate | Sodium lauryl sulfoacetate is not an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. |
| Nandrolone | Nandrolone, also known as 19-nortestosterone or 19-norandrostenolone, is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. |
| Inositol | An ingredient found in a variety of nutritional products. |
| Oxabolone cipionate | Used as a performance enhancing drug illicitly in athletes. |
| Pepsin | Used as a pancreatic enzyme replacement in pancreatic insufficiency . It is intended to mimic naturally produced human pepsin .
Pepsin powder is prepared from the gastric mucosa of pigs,... |
| Piprozolin | Not Annotated |
| Arginine glutamate | Not Annotated |
| Bismuth subnitrate | A medication used as an antacid. |
| Calcium lactate | An ingredient found in a variety of nutritional products. |
| Perboric acid | In the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid... |
| Phthalylsulfathiazole | Phthalylsulfathiazole is a broad spectrum antibiotic which is part of the drug class, sulfonamides. It was used as an antibiotic for bowel surgery, and for infections of the colon . |
| Magnesium silicate | Magnesium silicate is used to absorb moisture, prevent caking, and to improve the feel of a product. In the pharmaceutical companies, it is used as a dietary supplement, as part... |
| Methylmethionine chloride | Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also... |
| Prifinium | Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome . |
| Acetarsol | An anti infective used to treat a wide variety of infections in the body. |
| Idanpramine | Not Annotated |
| Aluminium acetoacetate | Aluminium acetoacetate is an aluminum containing antacid. |
| Etilamfetamine | Etilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this... |
| Olaflur | Olaflur which is also referred to as elmex gel is an ingredient used in toothpaste which helps in the prevention of dental caries. |
| Sulglicotide | Not Annotated |
| Trepibutone | Not Annotated |
| Hydrotalcite | Not Annotated |
| Nifurzide | Not Annotated |
| Piperidolate | Not Annotated |
| Magnesium aspartate | Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts... |
| Trimethyldiphenylpropylamine | Not Annotated |
| Calcium lactate gluconate | Not Annotated |
| Hydrochloric acid | Not Annotated |
| Benzilone | Not Annotated |
| Difemerine | Not Annotated |
| Adrenalone | Not Annotated |
| Carbutamide | Not Annotated |
| Sulbutiamine | Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic,... |
| Troxipide | Not Annotated |
| Proglumide | Not Annotated |
| Fenpiprane | Not Annotated |
| Citiolone | Not Annotated |
| Guar gum | Not Annotated |
| Diisopromine | Not Annotated |
| Quinbolone | Not Annotated |
| Magnesium peroxide | Not Annotated |
| Cyclobutyrol | Not Annotated |
| Valethamate | Not Annotated |
| Otilonium | Not Annotated |
| Poldine | Not Annotated |
| Clebopride | Not Annotated |
| Alginic acid | Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress . |
| Cerium oxalate | Not Annotated |
| Pentaerithrityl | Not Annotated |
| Nicofetamide | Not Annotated |
| Broxyquinoline | Not Annotated |
| Bevonium | Not Annotated |
| Clobenzorex | Not Annotated |
| Benzoxonium | Not Annotated |
| Succinylsulfathiazole | Not Annotated |
| Rociverine | Not Annotated |
| Metandienone | Not Annotated |
| Calcium pangamate | Not Annotated |
| Metopimazine | Not Annotated |
| Zolimidine | Not Annotated |
| Almasilate | Almasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is... |
| Potassium gluconate | Because of potassium’s wide-ranging roles in the body, low intakes can increase the risk of illness .
Potassium supplements are indicated to prevent hypokalemia in patients who would be at... |
| Aluminium glycinate | Not Annotated |
| Acetoxolone | Not Annotated |
| Aloglutamol | Aloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro. |
| Montmorillonite | Not Annotated |
| Tiemonium iodide | Not Annotated |
| Dimethylaminopropionylphenothiazine | Not Annotated |
| Metahexamide | Not Annotated |
| Dihexyverine | Not Annotated |
| Penthienate | Not Annotated |
| Tibezonium iodide | Not Annotated |
| Sodium tartrate | It acts as an emulsifier and pH control agent in food products , .
In the laboratory, it is used while performing the Karl Fischer equation, which is used to... |
| Metenolone | Not Annotated |
| Diphemanil | Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). |
| Sulfaguanidine | Not Annotated |
| Camylofin | Not Annotated |
| Tidiacic arginine | Not Annotated |
| Magnesium gluconate | A mineral supplement used to treat or prevent hypomagnesemia. |
| Glycyrrhizic acid | Glycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to... |
| Fenpiverinium | Not Annotated |
| Niperotidine | Not Annotated |
| Tilactase | A beta-D-galactosidase use to treat lactose intolerance. |
| Dexrabeprazole | Not Annotated |
| Emetonium iodide | Not Annotated |
| Magnesium orotate | Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat... |
| Chlorbenzoxamine | Not Annotated |
| Calcium levulinate | This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and... |
| Epomediol | Not Annotated |
| Proxazole | Not Annotated |
| Enprostil | Not Annotated |
| Calcium silicate | Not Annotated |
| Methylatropine | Not Annotated |
| Caroverine | Not Annotated |
| Pipenzolate | Not Annotated |
| Timepidium | Not Annotated |
| Mefenorex | Not Annotated |
| Anethole trithione | A medication used to treat dry mouth associated with medication or radiotherapy of the head and neck. |
| Nifuroxazide | Not Annotated |
| Becaplermin | A recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area. |
| Ascorbic acid | A vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron. |
| Calcitriol | An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. |
| Vitamin A | A vitamin important for retinal function that is used clinically to correct vitamin A deficiency. |
| Cholecalciferol | A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. |
| Trospium | An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). |
| Doxycycline | A tetracycline antibiotic used to treat a wide variety of bacterial infections. |
| Calcium acetate | A phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism. |
| Beclomethasone dipropionate | An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. |
| Betamethasone | A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. |
| Vancomycin | A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections. |
| Triamcinolone | A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. |
| Nystatin | A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species. |
| Magnesium sulfate | A drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany. |
| Naltrexone | A narcotic antagonist used in opioid overdose. |
| Hydrocortisone | A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. |
| Mannitol | A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. |
| Tetracycline | An antibiotic used to treat a wide variety of susceptible infections. |
| Sulfasalazine | An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. |
| Colistin | A polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria. |
| Natamycin | A macrolide antifungal used to treat fungal infections of the eye. |
| Prednisolone | A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. |
| Chlorhexidine | An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. |
| Metronidazole | A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. |
| Neomycin | An aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body. |
| Cromoglicic acid | A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. |
| Minocycline | A tetracycline analog used to treat a wide variety of infections in the body. |
| Amlexanox | Used as a paste in the mouth to treat aphthous ulcers (canker sores). |
| Amoxicillin | A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections. |
| Tolbutamide | A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Levofloxacin | A fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague. |
| Calcium chloride | An ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate. |
| Kanamycin | An aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. |
| Budesonide | A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. |
| Dexamethasone | A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. |
| Ephedrine | An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. |
| Calcium | A mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency. |
| Alfacalcidol | A vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure. |
| Iron | An essential element commonly used for the treatment of patients with documented iron deficiency. |
| Sorbitol | A product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener. |
| Prasterone | A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. |
| Stanolone | A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure... |
| Beta carotene | A vitamin A precursor found in various nutritional supplements and health products. |
| Hexetidine | An topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa. |
| Benzydamine | A locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy. |
| Tixocortol | A corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis. |
| Chlortetracycline | The first tetracycline antibiotic most commonly used for veterinary purposes. |
| Magnesium hydroxide | An inorganic compound used as a laxative and antacid. |
| Sodium chloride | An ingredient found in a variety of nutritional products as a source of electrolytes and water. |
| Zinc sulfate | A drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. |
| Dexpanthenol | An alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN). |
| Magnesium chloride | An ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies. |
| Hydrogen peroxide | A compound used as a disinfectant and sterilizer. |
| Emepronium | Not Annotated |
| Mepartricin | Not Annotated |
| Zinc acetate | A medication used to treat zinc deficiency. |
| Magnesium levulinate | Not Available |
| Magnesium lactate | Not Available |
| Aluminium phosphate | Not Available |
| Plantago ovata seed | Not Annotated |
| Loperamide oxide | Not Annotated |
| Calcium polycarbophil | A bulk forming laxative used to treat constipation. |
| Ornithine | An amino acid commonly found as a component in total parenteral nutrition. |
| Rosuvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
| Crofelemer | An antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy. |
| Migalastat | An alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant. |
| Triethylenetetramine | A copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate. |
| Cinitapride | It is indicated to treat gastrointestinal disorders associated with motility disturbances like gastroesophageal reflux disease (GERD), non-ulcer dyspepsia and delayed gastric emptying. |
| Metreleptin | A leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy. |
| Uridine triacetate | A pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine. |
| Eluxadoline | A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea. |
| Rolapitant | A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy. |
| Rebamipide | Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer. |
| Naldemedine | An opioid antagonist used to to treat opioid-induced constipation. |
| Ipragliflozin | Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2. |
| Ertugliflozin | A SGLT2 inhibitor used to treat type 2 diabetes mellitus. |
| Vestronidase alfa | A recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII. |
| Velmanase alfa | Recombinant Human Alpha Mannosidase has been investigated for the treatment of Alpha Mannosidosis and Alpha-Mannosidosis. |
| Evogliptin | Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2. |
| Plecanatide | A laxative used to treat chronic idiopathic constipation and IBS with constipation. |
| Cerliponase alfa | An enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency. |
| Semaglutide | A glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus. |
| Telotristat | A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat. |
| Polymyxin B | A polymyxin antibiotic used to treat a wide variety of infections in the body. |
| Acetylsalicylic acid | A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. |
| Karaya gum | An extract from Karaya gum used in allergy testing. |
| Mosapride | Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). Mosapride has been investigated for the treatment and diagnostic of Constipation, Type... |
| Vonoprazan | Vonoprazan has been used in trials studying the treatment of Erosive Esophagitis. |
| Rifamycin | An antibacterial used to treat traveler's diarrhea. |
| Sotagliflozin | Sotagliflozin has been used in trials studying the treatment of Renal impairment, Hepatic Impairment, Type 1 Diabetes Mellitus, and High Level of Sugar (Glucose) in the Blood. |
| Pegvaliase | An enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment. |
| Agalsidase alfa | A recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide. |
| Pitofenone | Not Annotated |
| Idursulfase beta | Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase). |