Bococizumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Bococizumab
DrugBank Accession Number
DB12456
Background

Bococizumab has been used in trials studying the treatment and prevention of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, and Heterozygous Familial Hypercholesterolemia.

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • Bococizumab
External IDs
  • PF-04950615

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Avoid life-threatening adverse drug events & improve clinical decision support.
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Bococizumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Bococizumab.
AducanumabThe risk or severity of adverse effects can be increased when Aducanumab is combined with Bococizumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Bococizumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Bococizumab.
AmivantamabThe risk or severity of adverse effects can be increased when Bococizumab is combined with Amivantamab.
AnifrolumabThe risk or severity of adverse effects can be increased when Anifrolumab is combined with Bococizumab.
AnsuvimabThe risk or severity of adverse effects can be increased when Bococizumab is combined with Ansuvimab.
Anthrax immune globulin humanThe risk or severity of adverse effects can be increased when Anthrax immune globulin human is combined with Bococizumab.
Antilymphocyte immunoglobulin (horse)The risk or severity of adverse effects can be increased when Antilymphocyte immunoglobulin (horse) is combined with Bococizumab.
Interactions
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Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
45M75JVK38
CAS number
1407495-02-6

References

General References
Not Available
PubChem Substance
347911335
Wikipedia
Bococizumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentHeterozygous Familial Hypercholesterolemia (HeFH)1
3CompletedTreatmentHyperlipidemias5
3TerminatedPreventionCardiovascular Disease (CVD)2
3TerminatedTreatmentCardiovascular Disease (CVD) / Dyslipidemia1
3WithdrawnTreatmentPrimary Hyperlipidemia or Mixed Dyslipidemia1
2CompletedTreatmentDyslipidemia / High Cholesterol2
2CompletedTreatmentHigh Cholesterol2
1CompletedBasic ScienceDyslipidemia / High Cholesterol / Hyperlipidemias / Metabolic Diseases / Metabolism Disorder, Lipid1
1CompletedBasic ScienceHealthy Subjects (HS)1
1CompletedBasic ScienceHigh Cholesterol2

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 20, 2016 22:27 / Updated on February 21, 2021 18:53