Antimetabolites

DBCAT000276Therapeutic categoryL01B

Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033). A DrugBank category of 73 drugs. 41 of them are approved.

ATC classification: L — ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 — ANTINEOPLASTIC AGENTS
L01B — ANTIMETABOLITES
Drugs: 2-deoxyglucose
2'-Deoxyuridine
5,6-dihydro-5-azacytidine
6-diazo-5-oxo-L-norleucine
8-azaguanine
Acivicin
Alirocumab
Allopurinol
Ancitabine
Azacitidine
Azacosterol
Azathioprine
Bendazac
Bococizumab
Broxuridine
Buthionine sulfoximine
Capecitabine
Carmofur
Choline
Cladribine
Clofarabine
Cycloserine
Cytarabine
Decitabine
Dezaguanine
and 48 more with a free account

What you can answer from here — as of May 04, 2026

73DrugsEach linked to its full drug card

119Drug targetsEvery drug–target pair in the class, with bond type

6,906Marketed productsAcross the regions we cover, with dosage forms and routes

20Routes of administrationHow the drugs in this class are given

1SubcategoryNarrower classes within this one

Which targets do Antimetabolites share, and which companies have late-stage candidates in this class?

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