| Indinavir | A protease inhibitor used to treat HIV infection. |
| Lovastatin | An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. |
| Amlodipine | A calcium channel blocker used to treat hypertension and angina. |
| Nisoldipine | A calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension. |
| Alprazolam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. |
| Quinine | An alkaloid used to treat uncomplicated Plasmodium falciparum malaria. |
| Buspirone | An anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression. |
| Vincristine | A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. |
| Cisapride | A medication used to treat heartburn associated with GERD. |
| Imatinib | A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. |
| Astemizole | A second generation antihistamine used to treat allergy symptoms. |
| Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
| Tamoxifen | A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. |
| Midazolam | A short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. |
| Alfentanil | An opioid agonist used to induce and maintain anesthesia, as well as an analgesic. |
| Tadalafil | A phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. |
| Diazepam | A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. |
| Vardenafil | A phosphodiesterase 5 inhibitor used to treat erectile dysfunction. |
| Tacrolimus | A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis. |
| Sirolimus | An immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis. |
| Triazolam | A benzodiazepine used for short term treatment of insomnia. |
| Telithromycin | An ketolide used to treat community acquired pneumonia of mild to moderate severity. |
| Felodipine | A calcium channel blocker used to treat hypertension. |
| Nitrendipine | For the treatment of mild to moderate hypertension |
| Atorvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Pimozide | An antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder. |
| Chlorpheniramine | A histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. |
| Nifedipine | A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. |
| Clarithromycin | A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection. |
| Saquinavir | An HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency. |
| Aripiprazole | An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. |
| Erythromycin | A macrolide antibiotic used to treat and prevent a variety of bacterial infections. |
| Carbamazepine | An anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia. |
| Sildenafil | A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. |
| Quinidine | A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. |
| Trazodone | A serotonin uptake inhibitor used to treat major depressive disorder. |
| Cyclosporine | A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis. |
| Verapamil | A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. |
| Haloperidol | An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. |
| Azithromycin | A macrolide antibiotic used to treat a variety of bacterial infections. |
| Rosuvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Telaprevir | An NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections. |
| Boceprevir | A hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy. |
| Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
| Amiodarone | A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. |
| Isavuconazole | Indicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label].
Indicated for patients 18 years of age and older for the treatment of... |
| Atazanavir | An antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV. |
| Etravirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Amprenavir | A protease inhibitor used to treat HIV infection. |
| Nelfinavir | A viral protease inhibitor used in the treatment of HIV infection. |
| Fosamprenavir | An antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection. |
| Nefazodone | An antidepressant used in the treatment of depression. |
| Riociguat | A stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. |
| Simeprevir | A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. |
| Temsirolimus | A antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR. |
| Asunaprevir | Asunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis.... |
| Amitriptyline | A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. |
| Clomipramine | A tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder. |
| Cyclobenzaprine | A skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin. |
| Doxepin | A psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia. |
| Imipramine | A tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis. |
| Nortriptyline | A tricyclic antidepressant used in the treatment of depression. |
| Avanafil | A phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction. |
| Conivaptan | An antidiuretic hormone inhibitor used to raise serum sodium levels. |
| Darifenacin | An M3 muscarinic receptor blocker used to treat urinary incontinence. |
| Darunavir | A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. |
| Ebastine | Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria. |
| Everolimus | A mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies. |
| Ibrutinib | An antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. |
| Lomitapide | A microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke. |
| Naloxegol | A peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain. |
| Budesonide | A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. |
| Dasatinib | A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. |
| Dronedarone | An antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation. |
| Eletriptan | A triptan used for the treatment of migraines. |
| Eplerenone | An aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure. |
| Lurasidone | An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder. |
| Maraviroc | A CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection. |
| Quetiapine | A psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder. |
| Ticagrelor | A P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death. |
| Tolvaptan | A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia. |
| Aprepitant | A substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery. |
| Colchicine | An alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF). |
| Eliglustat | A glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers, based on the FDA-approved test. |
| Rilpivirine | A non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1). |
| Rivaroxaban | A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. |
| Methysergide | An ergot alkaloid used for the prophylaxis of migraine and cluster headaches. |
| Tianeptine | Used primarily in the treatment of major depressive disorder and anxiety . It is currently being studied for fibromyalgia pain treatment . |
| Trimipramine | A tricyclic antidepressant used to treat depression. |
| Estradiol | An estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate. |
| Estradiol cypionate | An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism. |
| Estradiol valerate | An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception. |
| Ethinylestradiol | An estradiol used as a contraceptive. |
| Mestranol | A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding. |
| Aminophylline | A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. |
| Theophylline | A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. |
| Bromocriptine | A dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. |
| Cabergoline | A dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes. |
| Dihydroergocornine | A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. |
| Dihydroergocristine | An ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's. |
| Dihydroergocryptine | Not Annotated |
| Dihydroergotamine | An ergot alkaloid used in the acute treatment of migraine headache and cluster headache. |
| Ergoloid mesylate | A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. |
| Ergometrine | An ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony. |
| Ergotamine | A alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. |
| Lisuride | For the management of Parkinson's Disease |
| Lysergic acid diethylamide | Debate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by... |
| Methylergometrine | An ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery. |
| Terguride | Not Annotated |
| Triamcinolone | A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. |
| Voriconazole | A triazole compound used to treat fungal infections. |
| Esomeprazole | A proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion. |
| Omeprazole | A proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection. |
| Propafenone | A Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias. |
| Lopinavir | An HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection. |
| Tipranavir | A protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor. |
| Phenprocoumon | Used for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation... |
| Teniposide | A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. |
| Ulipristal | A selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed. |
| Disopyramide | A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. |
| Methadone | An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. |
| Alfuzosin | An alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH). |
| Buprenorphine | A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. |
| Fostamatinib | A spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment. |
| Udenafil | Investigated for use/treatment in erectile dysfunction and hypertension. |
| Prednisone | A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. |
| Fluticasone | Fluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is... |
| Pantoprazole | A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. |
| Lansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Dexlansoprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Rabeprazole | A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. |
| Lacidipine | Indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors . |
| Allylestrenol | Allylestrenol was designed to be used for miscarriage prevention, prevention of premature labour and has been investigated for possible use in men for treatment for benign prostatic hyperplasia. |
| Betamethasone | A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. |
| Ciclesonide | A glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents. |
| Cortisone acetate | A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones. |
| Deflazacort | A corticosteroid used to treat Duchenne muscular dystrophy. |
| Dienogest | An oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol. |
| Dexamethasone | A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. |
| Dexamethasone isonicotinate | Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention. |
| Drospirenone | A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions. |
| Estrone | An estrogen used to treat perimenopausal and postmenopausal symptoms. |
| Estrone sulfate | An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders. |
| Etonogestrel | A long-acting synthetic derived progestin contraceptive used in various devices such as contraceptive rings and intradermal implants. |
| Flunisolide | An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma. |
| Fluocortolone | Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders. |
| Fluorometholone | An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. |
| Fluticasone furoate | An inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis. |
| Fluticasone propionate | A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. |
| Hydrocortisone | A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. |
| Hydrocortisone aceponate | For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... |
| Hydrocortisone acetate | A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis. |
| Hydrocortisone butyrate | A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. |
| Hydrocortisone cypionate | For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... |
| Hydrocortisone phosphate | For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many... |
| Hydrocortisone probutate | A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. |
| Hydrocortisone valerate | A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. |
| Hydroxyprogesterone caproate | A synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth. |
| Levonorgestrel | A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives. |
| Medroxyprogesterone acetate | A progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty. |
| Methylprednisolone | A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. |
| Norethisterone | A synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis. |
| Norgestimate | A progesterone used as a contraceptive and to treat acne vulgaris. |
| Norgestrel | A progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women. |
| Paramethasone | For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary... |
| Prasterone | A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. |
| Prednisolone | A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. |
| Progesterone | A hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. |
| Ramelteon | A melatonin receptor agonist used to treat insomnia. |
| Zolpidem | A sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. |
| Zidovudine | A dideoxynucleoside used in the treatment of HIV infection. |
| Diethylstilbestrol | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. |
| Dapsone | A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis. |
| Morphine | An opioid agonist used for the relief of moderate to severe acute and chronic pain. |
| 4-hydroxycoumarin | Not Available |
| Acenocoumarol | An anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction. |
| Clorindione | Clorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans. |
| Diphenadione | Not Annotated |
| Ethyl biscoumacetate | Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226) |
| Fluindione | Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for... |
| Warfarin | A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction. |
| Hexobarbital | For the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful... |
| Azelnidipine | For the treatment of hypertension. |
| Barnidipine | Indicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina. |
| Bencyclane | A vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels. |
| Benidipine | Benidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris. |
| Bepridil | For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). |
| Bioallethrin | Bioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin. |
| Carboxyamidotriazole | Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others. |
| Caroverine | Not Annotated |
| Cilnidipine | Cilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been... |
| Cinnarizine | For the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins. |
| Clevidipine | A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable. |
| Cyclandelate | A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. |
| Darodipine | Darodipine is a calcium channel blocker. |
| Dexniguldipine | Not Annotated |
| Dexverapamil | Not Annotated |
| Dotarizine | Investigated for use/treatment in migraine and cluster headaches. |
| Efonidipine | For the treatment of hypertension. |
| Emopamil | Prevents renal injury after warm & cold ischemia. |
| Eperisone | Eperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression... |
| Ethosuximide | An anticonvulsant used to treat petit mal seizures. |
| Fendiline | Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective. |
| Fish oil | A source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement. |
| Flunarizine | A selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments. |
| Fluspirilene | An antipsychotic agent used in the treatment of schizophrenia. |
| Gallopamil | Gallopamil has been used in trials studying the treatment of Asthma. |
| Isradipine | A dihydropyridine calcium channel blocker used for the treatment of hypertension. |
| Lamotrigine | A phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder. |
| Lercanidipine | For the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome |
| Lidoflazine | Not Annotated |
| Lomerizine | Used to treat migraines. |
| Loperamide | A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis. |
| Manidipine | For the treatment of hypertension. |
| Levomenthol | An organic compound used to treat mild to moderate muscle and joint pain. |
| Mibefradil | For the treatment of angina and high blood pressure. |
| Naftopidil | Naftopidil has been investigated for the treatment of Disorder of Urinary Stent. |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. |
| Niludipine | Niludipine is a calcium channel blocker. |
| Nilvadipine | For the management of vasospastic angina, chronic stable angina and hypertension. |
| Nimesulide | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. |
| Nimodipine | A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. |
| Nylidrin | A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. |
| Niguldipine | Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. |
| Otilonium | Not Annotated |
| Penfluridol | Not Annotated |
| Perhexiline | For the management of severe angina pectoris. |
| Pinaverium | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. |
| Prenylamine | Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. |
| Terodiline | Not Annotated |
| Tetrahydropalmatine | Tetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity). |
| Tetrandrine | Not Annotated |
| Tolfenamic acid | In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. |
| Tranilast | For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. |
| Trimebutine | A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. |
| Trimethadione | An anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures. |
| Seletracetam | Investigated for use/treatment in epilepsy. |
| Vinpocetine | Vinpocetine has been investigated for the treatment of Epilepsy. |
| WIN 55212-2 | WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It... |
| Zonisamide | A sulfonamide anticonvulsant used to treat partial seizures. |
| Ivermectin | An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. |
| Ixabepilone | A microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. |
| Rifampicin | An antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis. |
| Rifabutin | An antibiotic used to treat mycobacterium avium complex disease in patients with HIV. |
| Rifapentine | An antibiotic agent used in the treatment of pulmonary tuberculosis. |
| Rifaximin | A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults. |
| Regorafenib | A kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma. |
| Ivabradine | A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. |
| Vemurafenib | A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. |
| Vortioxetine | An atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). |
| Pazopanib | An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. |
| Perampanel | A non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy. |
| Crizotinib | A receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive. |
| Cabozantinib | A tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer. |
| Isavuconazonium | A triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis. |
| Axitinib | An oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy. |
| Codeine | An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. |
| Apixaban | An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. |
| Pioglitazone | A thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. |
| Lapatinib | An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments. |
| Icotinib | Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy. |
| Cevimeline | A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome. |
| Bortezomib | A proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies. |
| Dofetilide | A class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter. |
| Ticlopidine | A platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA). |
| Reboxetine | For the treatment of clinical depression. |
| Ranolazine | An anti-anginal drug used for the treatment of chronic angina. |
| Ziprasidone | An atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia. |
| Conjugated estrogens | A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. |
| Bupivacaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Bexarotene | A retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy. |
| Vindesine | A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL). |
| Gefitinib | A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. |
| Terfenadine | For the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| Vinorelbine | A vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC. |
| Grepafloxacin | A fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections. |
| Mirtazapine | A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite. |
| Sorafenib | A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. |
| Eszopiclone | A sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. |
| Prochlorperazine | A phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting. |
| Loratadine | A second generation antihistamine used to manage the symptoms of allergic rhinitis. |
| Dronabinol | A synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. |
| Montelukast | A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. |
| Albendazole | A benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. |
| Erlotinib | An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers. |
| Rofecoxib | A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. |
| Toremifene | A first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers. |
| Bosentan | A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. |
| Vinblastine | A vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. |
| Enalapril | A prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure. |
| Testosterone | A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. |
| Efavirenz | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV. |
| Clofibrate | A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. |
| Mebendazole | A benzimidazole anthelmintic used to treat helminth infections. |
| Galantamine | A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. |
| Losartan | An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke. |
| Delavirdine | A non-nucleoside reverse transcriptase inhibitor used to treat HIV infection. |
| Nateglinide | A meglitinide used to treat non insulin dependent diabetes mellitus. |
| Zileuton | A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma. |
| Modafinil | A stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. |
| Dolasetron | An antinauseant and antiemetic used in chemotherapy and postoperatively. |
| Clopidogrel | An antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease. |
| Irinotecan | An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. |
| Etoposide | A podophyllotoxin derivative used to treat testicular and small cell lung tumors. |
| Roxithromycin | Used to treat respiratory tract, urinary and soft tissue infections. |
| Fentanyl | An opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management. |
| Mifepristone | A cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. |
| Donepezil | An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. |
| Granisetron | A 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively. |
| Ondansetron | A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively. |
| Tiagabine | An antiepileptic used to treat partial seizures. |
| Cocaine | An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities. |
| Paricalcitol | A vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease. |
| Tinidazole | A nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis. |
| Almotriptan | A 5-HT1B/1D receptor agonist used to treat migraines. |
| Salmeterol | A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. |
| Hydrocodone | An opioid agonist used as an analgesic and antitussive agent. |
| Zaleplon | A sedative used for short term treatment of insomnia in adults. |
| Exemestane | An aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen. |
| Doxorubicin | A medication used to treat various cancers and Kaposi's Sarcoma. |
| Levobupivacaine | For the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management |
| Letrozole | An aromatase inhibitor used to treat breast cancer in postmenopausal women. |
| Busulfan | An alkylating agent used to treat chronic myelogenous leukemia. |
| Cinacalcet | A calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma. |
| Isosorbide mononitrate | A nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease. |
| Ketoconazole | A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. |
| Oxybutynin | An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. |
| Clonazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. |
| Sibutramine | A norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity. |
| Dutasteride | An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase. |
| Cilostazol | An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. |
| Itraconazole | An antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis. |
| Escitalopram | A selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD). |
| Domperidone | A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. |
| Clindamycin | A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria. |
| Estazolam | A benzodiazepine used for the short-term management of insomnia. |
| Finasteride | An antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase. |
| Halofantrine | An antimalarial used for the treatment of severe malaria. |
| Levacetylmethadol | For the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients. |
| Paclitaxel | A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. |
| Retapamulin | A topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes. |
| Sitagliptin | An oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus. |
| Sunitinib | A receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). |
| Posaconazole | A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients. |
| Alosetron | A 5-HT3 antagonist used to treat diarrhea-predominant IBS. |
| Tiotropium | A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). |
| Solifenacin | A muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder. |
| Palonosetron | A serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting. |
| Valdecoxib | A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. |
| Sertindole | Used in the treatment of schizophrenia. |
| Tesmilifene | Intended for the treatment of various forms of cancer. |
| Etoricoxib | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. |
| Rimonabant | For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated... |
| Vicriviroc | Investigated for use/treatment in HIV infection and viral infection. |
| Laquinimod | Investigated for use/treatment in multiple sclerosis. |
| Fluvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Rotigotine | A non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome. |
| Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
| Risperidone | A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. |
| Selegiline | A monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's. |
| Halothane | A general inhalation anesthetic used for the induction and maintenance of general anesthesia. |
| Ifosfamide | An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma. |
| Meloxicam | An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. |
| Citalopram | A selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression. |
| Fluoxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I. |
| Sertraline | A selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. |
| Mianserin | For the treatment of depression. |
| Antipyrine | An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. |
| Cyclophosphamide | A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma. |
| Trabectedin | An alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma). |
| Venlafaxine | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression. |
| Terbinafine | An allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections. |
| Azelastine | A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. |
| Caffeine | A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. |
| Dextromethorphan | An NMDA receptor antagonist used to treat cases of dry cough. |
| Docetaxel | A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. |
| Lidocaine | A local anesthetic used in a wide variety of superficial and invasive procedures. |
| Propranolol | A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. |
| Ambrisentan | A selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications. |
| Benzphetamine | A sympathomimetic used to manage exogenous obesity short term. |
| Bisoprolol | A beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension. |
| Bromazepam | A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. |
| Calcitriol | An active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. |
| Chlordiazepoxide | A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. |
| Chloroquine | An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. |
| Clobazam | A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. |
| Clorazepic acid | A benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal. |
| Dantrolene | A direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis. |
| Digitoxin | A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. |
| Felbamate | An anticonvulsant used to treat severe epilepsy. |
| Fesoterodine | An antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. |
| Flurazepam | A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. |
| Flutamide | An antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma. |
| Guanfacine | An alpha-2A adrenergic receptor agonist used to treat ADHD. |
| Mefloquine | An antimalarial agent used as a schizonticidal agent. |
| Nilotinib | A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. |
| Oxycodone | An opioid used in the management of moderate to severe pain. |
| Pipotiazine | An antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients. |
| Praziquantel | An anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis. |
| Primaquine | An antimalarial indicated to prevent relapse of vivax malaria. |
| Dextropropoxyphene | An opioid analgesic used to treat mild to moderate pain. |
| Repaglinide | A antihyperglycemic used to improve glycemic control in diabetes. |
| Romidepsin | A histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma. |
| Silodosin | An alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH). |
| Spiramycin | A macrolide antimicrobial agent used in the treatment of various bacterial infections. |
| Tamsulosin | An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. |
| Tetracycline | An antibiotic used to treat a wide variety of susceptible infections. |
| Tolterodine | A muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency. |
| Tramadol | A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. |
| Trimethoprim | An antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. |
| Zopiclone | A nonbenzodiazepine hypnotic used for the short-term management of insomnia. |
| Phenytoin | An anticonvulsant drug used in the prophylaxis and control of various types of seizures. |
| Ketamine | A rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant. |
| Saxagliptin | An DPP-4 inhibitor used for the management of type 2 diabetes mellitus. |
| Sufentanil | An opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain. |
| Bicalutamide | An androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate. |
| Aminophenazone | Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water. |
| Clozapine | An antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. |
| Promazine | A phenothiazine used to manage schizophrenia. |
| Carvedilol | A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. |
| Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| Celecoxib | An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. |
| Glyburide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Sulfinpyrazone | A platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout . |
| Seratrodast | Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. |
| Ketobemidone | For the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures. |
| Adinazolam | For the treatment of anxiety and status epilepticus. |
| Temazepam | A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia. |
| Vanoxerine | Not Available |
| Cholecalciferol | A form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease. |
| Oxymorphone | An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. |
| Orphenadrine | A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. |
| Cabazitaxel | An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. |
| Desvenlafaxine | An antidepressant agent and SNRI used for the treatment of major depressive disorders in adults. |
| Artemether | An antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. |
| Lumefantrine | An antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum. |
| Ambroxol | Ambroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing. |
| Argatroban | A synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use. |
| Bezafibrate | A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. |
| Brinzolamide | A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| Carbinoxamine | A first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions. |
| Cephalexin | A first generation cephalosporin used to treat certain susceptible bacterial infections. |
| Chlorpromazine | A phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children. |
| Chlorzoxazone | A drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions. |
| Clofazimine | A riminophenazine antimycobacterial used to treat leprosy. |
| Clomethiazole | Investigated for use/treatment in strokes. |
| Clotiazepam | For the treatment of anxiety disorders. |
| Cytarabine | A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia. |
| Daunorubicin | An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. |
| Dihydrocodeine | An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. |
| Disulfiram | A carbamate derivative used to treat alcohol addiction. |
| Dorzolamide | A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. |
| Epinastine | An H1 receptor antagonist used to prevent itching in allergic conjunctivitis. |
| Estramustine | An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting. |
| Ethanol | For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical... |
| Ethylmorphine | Ethylmorphine is an analgesic used for pain relief. |
| Famciclovir | A nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster. |
| Fenofibrate | A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. |
| Flunitrazepam | For short-term treatment of severe insomnias, that are not responsive to other hypnotics. |
| Fulvestrant | An estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-. |
| Glipizide | A sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release. |
| Histamine | An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. |
| Imiquimod | A toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata. |
| Quinacrine | For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions. |
| Methaqualone | For the treatment of insomnia, and as a sedative and muscle relaxant. |
| Methoxyflurane | For use in the induction and maintenance of general anesthesia |
| Methyltestosterone | A synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females. |
| Mexiletine | A class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. |
| Nicotine | A stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. |
| Nitrazepam | A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. |
| Olopatadine | A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. |
| Acetaminophen | An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. |
| Permethrin | An insecticide used to prevent infestation with Sarcoptes scabiei (scabies). |
| Perphenazine | A phenothiazine used to treat schizophrenia as well as nausea and vomiting. |
| Meperidine | An opioid agonist with analgesic and sedative properties used to manage severe pain. |
| Phenacetin | Used principally as an analgesic. |
| Prazepam | For the treatment of anxiety disorders. |
| Proguanil | A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria. |
| Quazepam | A long -acting benzodiazepine used to manage insomnia. |
| Ropivacaine | An analgesic drug used for local or regional anesthesia for surgery and short-term management of pain. |
| Sevoflurane | A inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures. |
| Sulfadiazine | A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. |
| Tasosartan | Tasosartan is infrequently in the treatment of hypertension and heart failure. |
| Thiotepa | An alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas. |
| Troleandomycin | For the treatment of bacterial infection. |
| Yohimbine | An alpha-2-adrenergic blocker and sympatholytic found in supplements used to. |
| Zomepirac | Zomepirac was indicated for the management of mild to severe pain. |
| Ketazolam | A long-acting benzodiazepine used to manage anxiety and insomnia. |
| Paramethadione | Used for the control of absence (petit mal) seizures that are refractory to treatment with other medications. |
| Tretinoin | A vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles. |
| Iloperidone | An atypical antipsychotic agent used for the acute treatment of schizophrenia in adults. |
| Vilazodone | An antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors. |
| Clonidine | An alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines. |
| Indapamide | A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. |
| Ivacaftor | A cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication. |
| Banoxantrone | For the treatment of various forms of cancer. |
| Indacaterol | An inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma. |
| Chenodeoxycholic acid | A bile acid used for the treatment of primary biliary cirrhosis. |
| Pinacidil | Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood... |
| Pimecrolimus | A topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons. |
| Vismodegib | A hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. |
| Prasugrel | A P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI. |
| Asenapine | An atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia. |
| Brentuximab vedotin | A CD30-directed antibody-drug conjugate used to treat various types of lymphoma. |
| Lorcaserin | A serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities. |
| Vandetanib | An antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease. |
| Ruxolitinib | A kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment. |
| Abiraterone | An antiandrogen used in the treatment of prostate cancer. |
| Mirabegron | A beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB). |
| Enzalutamide | An androgen receptor inhibitor used to treat castration-resistant prostate cancer. |
| Tofacitinib | A Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine. |
| Bosutinib | An antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments. |
| Ponatinib | A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). |
| Bedaquiline | A diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB). |
| Canagliflozin | A sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM. |
| Alogliptin | A dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus. |
| Ospemifene | A non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. |
| Pomalidomide | A thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma. |
| Dabrafenib | A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. |
| Trastuzumab emtansine | An antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer. |
| Taurochenodeoxycholic acid | Taurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy. |
| Mycophenolate mofetil | An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. |
| Levomilnacipran | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD). |
| Macitentan | An endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression. |
| Dapagliflozin | A sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus. |
| Apremilast | A non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis. |
| Olaparib | A chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy. |
| Palbociclib | An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer. |
| Vilanterol | A long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. |
| Aliskiren | A direct renin inhibitor used to manage hypertension. |
| Elvitegravir | An antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. |
| Cariprazine | An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder. |
| Parecoxib | A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. |
| Brexpiprazole | A serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia. |
| Rolapitant | A neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy. |
| Flibanserin | A 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). |
| Daclatasvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Sonidegib | An antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate. |
| Panobinostat | A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. |
| Ixazomib | A monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already. |
| Selexipag | A non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension. |
| Dasabuvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Paritaprevir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
| Synthetic Conjugated Estrogens, A | A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal atrophy and dyspareunia. |
| Synthetic Conjugated Estrogens, B | A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal dryness. |
| Venetoclax | A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. |
| Esterified estrogens | A female hormone used to treat conditions related to estrogen deficiency and moderate to severe vasomotor menopausal symptoms in women. |
| Rucaparib | An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. |
| Safinamide | A MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes. |
| Deutetrabenazine | A vesicular monoamine transporter 2 inhibitor used for the symptomatic treatment of chorea in Huntington's disease and tardive dyskinesia. |
| Dexchlorpheniramine maleate | A first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. |
| Velpatasvir | A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. |
| Brivaracetam | An anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain. |
| Valbenazine | A vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia. |
| Odanacatib | Investigated for use/treatment in osteoporosis . |
| Grazoprevir | An antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections. |
| Perospirone | For the treatment of schizophrenia and acute cases of bipolar mania. |
| Etizolam | Indicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia. |
| Rupatadine | A selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis. |
| Imidafenacin | Used in the treatment of overactive bladder [FDA Label]. |
| Neratinib | A protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor. |
| Voxilaprevir | A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. |
| Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| Midostaurin | An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL). |
| Elbasvir | An antiviral and NS5A inhibitor used to treat hepatitis C infections. |
| Copanlisib | A medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments. |
| Abemaciclib | A medication used to treat HR+ HER2- advanced or metastatic breast cancer. |
| Brigatinib | An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. |
| Baricitinib | A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. |
| Macimorelin | A medication used to treat adult growth hormone deficiency. |
| Blonanserin | Used for the treatment of schizophrenia . |
| Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
| Testosterone cypionate | An androgen used to treat low or absent testosterone. |
| Testosterone enanthate | An androgen used to treat low or absent testosterone. |
| Testosterone undecanoate | An androgen used to treat low or absent testosterone. |
| Estradiol acetate | An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause. |
| Estradiol benzoate | Estradiol benzoate is not currently available in any FDA or Health Canada approved products. |
| Estradiol dienanthate | Estradiol dienanthate is not currently available in any FDA or Health Canada approved products. |
| Piperaquine | For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638. |
| Testosterone propionate | A slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles. |
| Bictegravir | An integrase inhibitor used to treat HIV infections. |
| Apalutamide | An androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer. |
| Zotepine | Zotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes... |
| Pitolisant | An antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults. |
| Tezacaftor | A medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis. |
| Opium | A medication used to treat moderate to severe pain. |
| Tocopherol | Tocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and... |
| alpha-Tocopherol acetate | A form of vitamin E used to treat and prevent vitamin deficiencies. |
| Propiverine | An antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency. |
| Nabiximols | In Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have... |
| Medical Cannabis | The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical... |
| Vinflunine | A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed. |
| Tocofersolan | A derivative of alpha tocopherol used to treat vitamin E deficiencies. |
| Delamanid | An antibiotic used to treat multidrug resistant tuberculosis. |
| Fosnetupitant | A medication used in combination with others to prevent chemotherapy associated nausea and vomiting. |
| Dihydro-alpha-ergocryptine | A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity. |
| Ipecac | An emetic agent used to induce vomiting in poisoning. |
| Midecamycin | Midecamycin was used for the treatment of infections in the oral cavity, upper and lower respiratory tracts and skin and soft tissue infections. The alone use of midecamycin was mainly... |
| Aripiprazole lauroxil | An antipsychotic used to treat schizophrenia in adults. |
| Encorafenib | A kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations. |
| Segesterone acetate | Segesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen... |
| Fosphenytoin | An antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. |
| Cobicistat | A CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection. |
| Dapoxetine | For the treatment of premature ejaculation. |
| Linagliptin | A dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus. |
| Cobimetinib | An antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma. |
| Osimertinib | A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. |
| Netupitant | An antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy. |
| Ceritinib | An antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib. |
| Ribociclib | A kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer. |
| Nintedanib | A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer. |
| Roflumilast | A selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis. |
| Suvorexant | A orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance. |
| Tasimelteon | A melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder. |
| Vorapaxar | A platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD). |
| Zuclopenthixol | An antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance. |
| Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
| Lacosamide | An antiepileptic drug used to treat partial onset seizures in adults. |
| Pranlukast | Used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. |
| Eravacycline | A tetracycline antibiotic used to treat complicated intra-abdominal infections. |
| Fosaprepitant | An antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy. |
| Cethromycin | A ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia. |
| Tegafur | An antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers. |
| Doravirine | A non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections. |
| Duvelisib | An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. |
| Nevirapine | A non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection. |
| (R)-warfarin | Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in... |
| Ivosidenib | An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation. |
| 3,5-diiodothyropropionic acid | DITPA has been investigated in Congestive Heart Failure. |
| 5-androstenedione | 5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its... |
| Alclometasone | A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. |
| Aldosterone | A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. |
| Amcinonide | A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses. |
| Androstenedione | A delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as... |
| Beclomethasone dipropionate | An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. |
| Clobetasol | Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. |
| Clobetasol propionate | A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis. |
| Clobetasone | A corticosteroid used to treat dry eyes, eczema, and dermatitis. |
| Corticosterone | An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) |
| Corticotropin | A diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency. |
| Cyproterone acetate | A steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer |
| Nomegestrol | Nomegestrol is an ingredient in the EMA-authorised product Zoely. |
| Nomegestrol acetate | Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders. |
| Desogestrel | A synthetic progestin used in contraception, often in combination with ethinyl estradiol. |
| Desonide | A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. |
| Desoxycorticosterone acetate | Not Annotated |
| Desoxycorticosterone pivalate | Examined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of... |
| Difluocortolone | A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis. |
| Difluprednate | A topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery. |
| Dydrogesterone | Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history... |
| Equilenin | Equilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine... |
| Equilin | For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and... |
| Etynodiol | Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers... |
| Ethynodiol diacetate | An oral contraceptive used to prevent pregnancy. |
| Fludrocortisone | A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. |
| Flumethasone | A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. |
| Fluocinolone acetonide | A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye. |
| Fluocinonide | A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions. |
| Fluprednidene | Fluprednidene is a corticosteroid. |
| Fluprednisolone | A synthetic glucocorticoid with anti-inflammatory properties. |
| Flurandrenolide | A corticosteroid used to treat corticosteroid-responsive dermatoses. |
| Gestodene | Gestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol... |
| Halcinonide | A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. |
| HE3286 | For the treatment of rheumatoid arthritis and type 2 diabetes. |
| Hydrocortisone succinate | A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. |
| Hydroxyprogesterone | Not Annotated |
| Liotrix | May be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic... |
| Loteprednol etabonate | A corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery. |
| Lynestrenol | Lynestrenol has been used in trials studying the basic science of Transsexualism and Gender Dysphoria. |
| Medrogestone | A progestin used as an adjunct to control secondary amenorrhea and dysfunctional bleeding in adolescent and adult females, and treat endometrial shedding in menopausal women. |
| Medrysone | A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions. |
| Megestrol acetate | A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy. |
| Melengestrol | Melengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals. |
| Meprednisone | Not Annotated |
| Mometasone | A corticosteroid with no indications. |
| Mometasone furoate | A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. |
| Norelgestromin | A progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception. |
| Norethynodrel | A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it... |
| Prednicarbate | A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. |
| Prednylidene | Prednylidene is an experimental systemic glucocorticoid. |
| Pregnenolone | A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. |
| Promegestone | Not Annotated |
| Rimexolone | A glucocorticoid used to treat inflammation of the eye. |
| Trilostane | Used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. |
| Atovaquone | An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria. |
| Gestrinone | Endometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700]. |
| Chlormadinone | Not Annotated |
| Quingestanol | Not Annotated |
| Demegestone | Demegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued. |
| (S)-Warfarin | Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in... |
| Thiamylal | Used for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state. |
| Agmatine | Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,... |
| Gemfibrozil | A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. |
| Balaglitazone | Balaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2. |
| Ciglitazone | Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.
Ciglitazone was never used as a medication, but it sparked interest in... |
| Lobeglitazone | Lobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use... |
| Netoglitazone | Netoglitazone (MCC-555) is a hypoglycemic agent. |
| Rivoglitazone | Rivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co. |
| Rosiglitazone | A thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. |
| Paliperidone | An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders. |
| 6-O-benzylguanine | 6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others. |
| Duloxetine | A serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. |
| Fluvoxamine | A selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder. |
| Indalpine | Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse... |
| Milnacipran | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder. |
| Fusidic acid | A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. |
| Aranidipine | Aranidipine has been used for many years to treat angina pectoris and hypertension. |
| Pyrazinamide | An antituberculosis agent used as a component of tuberculosis (TB) treatment. |
| Lenvatinib | A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. |
| Lorpiprazole | In 2016, lorpiprazole was classified in the "Chemical structure-related drug-like criteria of global approved drugs" as an antipsychotic and anxiolytic. An antipsychotic is a medication used to treat a state... |
| Propacetamol | Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. |
| Valproic acid | An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures. |
| Pentamidine | An antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. |
| Rufinamide | An antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS). |
| Lorazepam | A long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. |
| St. John's Wort | An herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety. |
| 9-aminocamptothecin | Aminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others. |
| Methylprednisone | Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others. |
| Dacomitinib | A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. |
| Nebivolol | A beta blocking agent used to treat hypertension and aid in the management of heart failure. |
| Larotrectinib | A kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments. |
| Lorlatinib | An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. |
| Gilteritinib | An AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia. |
| Benzodiazepine | Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary... |
| Brotizolam | Brotizolam is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia. |
| Vitamin D | An ingredient found in a variety of supplements and vitamins. |
| Desipramine | A tricyclic antidepressant used in the treatment of depression. |
| Doxazosin | An alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia. |
| 7-ethyl-10-hydroxycamptothecin | Investigated for use/treatment in colorectal cancer. |
| Prucalopride | A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST). |
| Glasdegib | A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy. |
| Doxycycline | A tetracycline antibiotic used to treat a wide variety of bacterial infections. |
| Phentermine | A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. |
| Metoprolol | A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. |
| Esketamine | A NMDA receptor antagonist used for treatment-resistant depression. |
| Siponimod | A medication used to treat relapsing multiple sclerosis. |
| Erdafitinib | A fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma. |
| Tenofovir alafenamide | A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. |
| Tenofovir | Tenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the... |
| Alpelisib | Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor... |
| Selinexor | Selinexor is indicated for the treatment of relapsed or refractory multiple myeloma in combination with dexamethasone.[label] Patients must have received at least 4 prior therapies and have disease which is... |
| Metronidazole | A nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections. |
| Clotrimazole | A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis. |
| Triclabendazole | An anthelmintic drug used to treat fascioliasis. |
| Vitamin E | An antioxidant vitamin used in many skin creams and multivitamin preparations. |
| Isotretinoin | A retinoid used to treat severe recalcitrant acne. |
| Rivastigmine | A cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's. |
| Paroxetine | A selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder. |
| Levocetirizine | An H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria. |
| Butyrfentanyl | A methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug. |
| Pexidartinib | An antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor. |
| Bimatoprost | A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. |
| Pretomanid | Part of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis. |
| Hydroxychloroquine | An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus. |
| Entrectinib | Entrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment... |
| Fedratinib | Fedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk. |
| Tranylcypromine | A monoamine oxidase inhibitor used to treat major depressive disorder. |
| Lefamulin | A pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP). |
| Sulfamethoxazole | An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. |
| Istradefylline | A selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease. |
| Zafirlukast | A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. |
| Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. |
| Flucloxacillin | A narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA). |
| Mexazolam | A benzodiazepine indicated to treat anxiety with or without psychoneurotic conditions. |
| Metoclopramide | An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. |
| Dexloxiglumide | For the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD). |
| Calanolide A | For use in combination treatment of HIV infection (AIDS). |
| Plitidepsin | Intended for the treatment of various forms of cancer. |
| Rifalazil | Investigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease. |
| Azimilide | Investigated for use/treatment in arrhythmia and atrial fibrillation. |
| Capravirine | Investigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection. |
| Polatuzumab vedotin | This medication is indicated to treat adults with relapsed or refractory diffuse large B-cell lymphoma in combination with bendamustine and rituximab that has returned of progressed after 2 or more... |
| Levamlodipine | A calcium channel blocker used to treat hypertension. |
| Fluprednisolone acetate | Not Annotated |
| Baloxavir marboxil | A polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza. |
| Tenapanor | An NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). |
| Anastrozole | A competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women. |
| Trifarotene | A topical retinoid indicated for the treatment of acne vulgaris. |
| Elexacaftor | A small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation. |
| Prednisolone acetate | A glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions. |
| Hydroxyzine | An antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria. |
| Zanubrutinib | A kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy. |
| Voxelotor | A drug used to inhibit the polymerization of hemoglobin S, preventing the painful and sometimes lethal vaso-occlusive crises associated with sickle cell disease. |
| Cenobamate | A small molecule drug indicated to treat partial onset seizures in adults. |
| Enfortumab vedotin | An antibody-drug conjugate comprised of a fully human monoclonal antibody and microtubule-disrupting chemotherapeutic agent used in the treatment of advanced or metastatic urothelial cancer. |
| Trastuzumab deruxtecan | An antibody used to treat certain types of unresectable or metastatic HER-2 positive breast cancer. |
| Lemborexant | A dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia. |
| Darolutamide | An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer. |
| Upadacitinib | An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis in adult patients who did not respond well to methotrexate. |
| Lumateperone | A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia. |
| Ubrogepant | An oral CGRP antagonist used in the acute treatment of migraine with or without aura. |
| Avapritinib | A selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors. |
| Tazemetostat | A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. |
| Rimegepant | An oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults. |
| Umifenovir | A dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses. |
| Osilodrostat | An oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism. |
| Norethindrone enanthate | Not Annotated |
| Ozanimod | A sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD). |
| Methotrexate | An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. |
| Selumetinib | A MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN). |
| Prednisolone phosphate | A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions. |
| Tucatinib | A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer. |
| Pemigatinib | A kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients. |
| Remdesivir | A nucleoside analog used to treat RNA virus infections including COVID-19. |
| Aldesleukin | A recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma. |
| Acalabrutinib | A Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. |
| Capmatinib | A kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping. |
| Alectinib | A kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. |
| Belinostat | A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). |
| Selpercatinib | A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations. |
| Ripretinib | A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST). |
| Apomorphine | A morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease. |
| Betamethasone phosphate | A fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions. |
| Lurbinectedin | A chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer. |
| Dexamethasone acetate | Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is... |
| Fenfluramine | Fenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures. |
| Fostemsavir | An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. |
| Risdiplam | An oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA). |
| Oliceridine | A biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists. |
| Pralsetinib | A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer. |