Cytochrome P-450 Substrates

Name
Cytochrome P-450 Substrates
Accession Number
DBCAT005101
Description
Not Available
Drugs
DrugDrug Description
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
CaffeineA stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth.
AnagrelideA platelet-reducing agent used to treat thrombocythemia, and its related complications, secondary to myeloproliferative neoplasms.
RopiniroleA non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
RopivacaineAn analgesic drug used for local or regional anesthesia for surgery and short-term management of pain.
ZolmitriptanA member of the triptan class of 5-HT(1B/1D/1F) receptor agonist drugs used for the acute treatment of migraine with or without aura in adults.
AmitriptylineA tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.
OlanzapineAn antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
ClozapineAn antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
GrepafloxacinA fluoroquinolone antibiotic used to treat various gram positive and gram negative bacterial infections.
MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
TacrineFor the palliative treatment of mild to moderate dementia of the Alzheimer's type.
ImipramineA tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.
DuloxetineA serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
FlutamideAn antiandrogen used for locally confined stage B2-C and D-2 metastatic prostate carcinoma.
HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
NortriptylineA tricyclic antidepressant used in the treatment of depression.
FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
PropranololA non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma.
EstroneAn estrogen used to treat perimenopausal and postmenopausal symptoms.
VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
RiluzoleA glutamate antagonist used to treat amyotrophic lateral sclerosis.
ZileutonA leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma.
EstradiolAn estrogenic steroid used to treat vasomotor symptoms of vulvar and vaginal atrophy in menopause, hypoestrogenism, prevention of postmenopausal osteoporosis, treatment of breast cancer, and advanced androgen-dependent carcinoma of the prostate.
DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
OndansetronA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
RamelteonA melatonin receptor agonist used to treat insomnia.
FrovatriptanA 5-HT1B/1D receptor agonist used to treat migraines.
LevobupivacaineFor the production of local or regional anesthesia for surgery and obstetrics, and for post-operative pain management
CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
PimozideAn antipsychotic used to manage debilitating motor and phonic tics in patients with Tourette's Disorder.
PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
ClomipramineA tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.
RasagilineAn irreversible inhibitor of monoamine oxidase used for the symptomatic management of idiopathic Parkinson's disease as initial monotherapy and as adjunct therapy to levodopa.
ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
ChlorpromazineA phenothiazine antipsychotic used to treat nausea, vomiting, preoperative anxiety, schizophrenia, bipolar disorder, and severe behavioral problems in children.
MephenytoinA phenylhydantoin used to treat refractory partial epilepsy.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
AzelastineA histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis.
AcenocoumarolAn anticoagulant drug used in the prevention of thromboembolic diseases in infarction and transient ischemic attacks, as well as management of deep vein thrombosis and myocardial infarction.
AminophenazoneFormerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water.
PalonosetronA serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
MelatoninAn endogenous hormone produced by the pineal gland that regulates sleep-wake cycles and when provided exogenously has beneficial effects on sleep-onset latency; available as an over-the-counter supplement.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DoxepinA psychotropic agent used for the treatment of depression, anxiety, manic-depressive disorder, and insomnia.
CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
ZolpidemA sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency.
FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
TerbinafineAn allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
CinnarizineFor the treatment of vertigo/meniere's disease, nausea and vomiting, motion sickness and also useful for vestibular symptoms of other origins.
FlunarizineA selective calcium-entry blocker used as migraine prophylaxis in patients with severe and frequent episodes who have not responded adequately to more common treatments.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
PhenacetinUsed principally as an analgesic.
AminophyllineA bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis.
AsenapineAn atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.
BetaxololA cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically).
Estrone sulfateAn estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
GuanabenzAn alpha-2 adrenergic agonist used to treat hypertension.
ThiothixeneAn antipsychotic indicated for the management of schizophrenia.
TrifluoperazineA phenothiazine used to treat depression, anxiety, and agitation.
PromazineA phenothiazine used to manage schizophrenia.
CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
AlbendazoleA benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
BromazepamA short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety.
DesipramineA tricyclic antidepressant used in the treatment of depression.
DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
EthanolFor therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
EtoposideA podophyllotoxin derivative used to treat testicular and small cell lung tumors.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
MalathionA parasympathomimetic organophosphate used to treat head lice.
MaprotilineA tetracyclic antidepressant used to treat depressive illness, major depressive disorder, bipolar disorder, and anxiety associated with depression.
MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
MethoxyfluraneFor use in the induction and maintenance of general anesthesia
MianserinFor the treatment of depression.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
PerphenazineA phenothiazine used to treat schizophrenia as well as nausea and vomiting.
SelegilineA monoamine oxidase inhibitor used to treat major depressive disorder and Parkinson's.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
ZiprasidoneAn atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.
ErlotinibAn EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
CilostazolAn antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication.
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
MuraglitazarInvestigated for use/treatment in diabetes mellitus type 2.
VadimezanInvestigated for use/treatment in solid tumors, lung cancer, ovarian cancer, and prostate cancer.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
PazopanibAn antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy.
UlipristalA selective progesterone receptor modulator used for emergency contraception after unprotected intercourse or in a situation where a planned method of contraception has failed.
LorcaserinA serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities.
ApixabanAn anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery.
AxitinibAn oral VEGFR and kinase inhibitor used for the treatment of advanced renal cell carcinoma after failure of one prior systemic therapy.
PomalidomideA thalidomide analogue used in combination with dexamethasone to treat patients with multiple myeloma.
IxazomibA monoclonal antibody used with other medications to treat multiple myeloma in patients who have received one other therapy already.
BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
RucaparibAn anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.
IcotinibIcotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.
DeutetrabenazineA vesicular monoamine transporter 2 inhibitor used for the symptomatic treatment of chorea in Huntington's disease and tardive dyskinesia.
StiripentolAn anticonvulsant agent used with clobazam and valproate as an adjunct to treat refractory generalized tonic-clonic seizures in Dravet syndrome.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
EnasidenibAn isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation.
Estradiol acetateAn estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
Estradiol benzoateEstradiol benzoate is not currently available in any FDA or Health Canada approved products.
Estradiol cypionateAn estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
Estradiol dienanthateEstradiol dienanthate is not currently available in any FDA or Health Canada approved products.
Estradiol valerateAn estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
ZotepineZotepine, like other atypical antipsychotics, is considered as the first-line treatment in newly diagnosed schizophrenia. It is usually thought to be an option of choice for managing acute schizophrenic episodes...
LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
TasimelteonA melatonin receptor agonist used to treat Non- 24-Hour Sleep-Wake Disorder.
PirfenidoneAn agent used for the treatment of idiopathic pulmonary fibrosis (IPF).
RamosetronFor the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males.
AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
DihydralazineDihydralazine is under investigation in clinical trial NCT00311974 (The Effect of Dihydralazine on Kidney Function and Hormones in Healthy Individuals).
PimobendanNot Annotated
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
PerampanelA non-competitive AMPA glutamate receptor antagonist used to treat partial-onset seizures with or without secondarily generalized seizures, and as adjunctive treatment of primary generalized tonic-clonic seizures in patients with epilepsy.
(R)-warfarinWarfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
6-O-benzylguanine6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others.
8-chlorotheophyllineWhen used in combination with DB01075 as the antiemetic DB00985, 8-chlorotheophylline is indicated for the prevention and treatment of nausea, vomiting, or vertigo of motion sickness.
HypoxanthineHypoxanthine is a purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
LisofyllineLisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
OxtriphyllineA bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema.
XanthineA purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being...
TemafloxacinFor the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
AcefyllineNot Annotated
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
BamifyllineBamifylline is a selective A1 adenosine receptor antagonist.
BromotheophyllineBromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
BufyllineNot Annotated
CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
EntecavirA nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
EtamiphyllineNot Annotated
FenethyllineNot Available
LobucavirLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
PeldesinePeldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
PenciclovirA topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
PentifyllineNot Annotated
PropentofyllineInvestigated for use/treatment in alzheimer's disease.
ProxyphyllineNot Annotated
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
CarmustineAn alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
LomefloxacinA fluoroquinolone used to prevent and treat a wide variety of infections in the body.
HesperetinFor lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
LeflunomideA pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
PraziquantelAn anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis.
TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
BinimetinibA medication used to treat metastatic melanoma with specific mutations.
AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
8-azaguanine8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.
9-DeazaguanineNot Available
9-MethylguanineNot Available
DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
SorafenibA kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.
AgomelatineAgomelatine is indicated to treat major depressive episodes in adults.
TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
DapagliflozinA sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
ApremilastA non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis.
ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
TamoxifenA selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women.
IstradefyllineA selective adenoside A2A receptor antagonist indicated in adjunct to levodopa and carbidopa for the treatment of Parkinson's Disease.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
LoratadineA second generation antihistamine used to manage the symptoms of allergic rhinitis.
GTS-21Investigated for use/treatment in alzheimer's disease and schizophrenia and schizoaffective disorders.
BicifadineFor the treatment of pain.
VortioxetineAn atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD).
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
HalothaneA general inhalation anesthetic used for the induction and maintenance of general anesthesia.
IfosfamideAn alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Valproic acidAn anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
MontelukastA leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis.
CisaprideA medication used to treat heartburn associated with GERD.
ClomethiazoleInvestigated for use/treatment in strokes.
CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
FlunitrazepamFor short-term treatment of severe insomnias, that are not responsive to other hypnotics.
SevofluraneA inhalation anaesthetic agent used for induction and maintenance of general anesthesia during surgical procedures.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
FlurazepamA long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia.
TretinoinA vitamin A derivative used to treat acne vulgaris, certain types of promyelocytic leukemia, and fine wrinkles.
ArformoterolA beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Tegafur-uracilTegafur-uracil is indicated for the first line treatment of metastatic colorectal cancer with concomitant administration of calcium folinate. Colorectal cancer is the third most diagnosed cancer and 30% of the...
AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis....
ArtesunateArtesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
PlitidepsinIntended for the treatment of various forms of cancer.
BupropionA norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.
MeperidineAn opioid agonist with analgesic and sedative properties used to manage severe pain.
PropofolA medication used in general anesthesia and for sedation.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
DosulepinIndicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.
LofepramineNot Annotated
MelitracenNot Annotated
TrimipramineA tricyclic antidepressant used to treat depression.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
PerhexilineFor the management of severe angina pectoris.
TramadolA centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.
SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
SeratrodastSeratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma.
DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
BenzphetamineA sympathomimetic used to manage exogenous obesity short term.
ArtemetherAn antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
BrompheniramineA histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
ClobazamA benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.
ClotiazepamFor the treatment of anxiety disorders.
EpinastineAn H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
EthylmorphineEthylmorphine is an analgesic used for pain relief.
IsofluraneAn inhaled general anesthetic used in surgery.
KetobemidoneFor the treatment of all types of severe pain, such as postoperative, cancer, kidney stones and fractures.
MethyltestosteroneA synthetic anabolic steroid used for the replacement therapy in conditions associated with testosterone deficiencies in males, such as hypogonadism, and treatment of advancing inoperable metastatic breast cancer in females.
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
TemazepamA short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia.
TestosteroneA hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.
BanoxantroneFor the treatment of various forms of cancer.
PrasugrelA P2Y12 platelet inhibitor used to reduce risk of thrombotic cardiovascular events in unstable angina or non-ST-elevation myocardial infarction (NSTEMI), and in patients with STEMI when managed with either primary or delayed PCI.
OspemifeneA non-hormonal estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.
RomidepsinA histone deacetylase (HDAC) inhibitor used to treat cutaneous and peripheral T-cell lymphoma.
VelpatasvirA NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
BrivaracetamAn anticonvulsant used for the treatment of partial-onset seizures that functions by binding to synaptic vesicle glycoprotein 2A (SV2A) in the brain.
Testosterone cypionateAn androgen used to treat low or absent testosterone.
Testosterone enanthateAn androgen used to treat low or absent testosterone.
Testosterone undecanoateAn androgen used to treat low or absent testosterone.
ArtemisininArtemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
EsketamineA NMDA receptor antagonist used for treatment-resistant depression.
HydrocodoneAn opioid agonist used as an analgesic and antitussive agent.
AmlodipineA calcium channel blocker used to treat hypertension and angina.
DiazepamA long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.
DexloxiglumideFor the treatment of Irritable Bowel Syndrome (IBS) and Gastroesophageal Reflux Disease (GERD).
MetoprololA beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction.
VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
AtomoxetineA selective norepinephrine reuptake inhibitor (SNRI) used in the management of Attention Deficit Hyperactivity Disorder (ADHD).
CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
OxycodoneAn opioid used in the management of moderate to severe pain.
ThioridazineA phenothiazine antipsychotic used to treat schizophrenia and generalized anxiety disorder.
RisperidoneA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
AripiprazoleAn atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
TafenoquineAn antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
OpipramolOpipramol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.
ProtriptylineA tricyclic antidepressant that is indicated in the treatment of depression only under close clinical supervision.
ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
ElagolixA gonadotropin releasing hormone receptor antagonist used to treat moderate to severe pain in endometriosis.
AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
AlprenololFor the treatment of hypertension, angina, and arrhythmia
AnisodamineAnisodamine has been investigated for the treatment of Intestinal Diseases.
ArotinololArtinolol was introduced to be used as an antihypertensive agent since 1986. It has been studied for other functions like tremor control for patients with Parkinson disease and it is...
AtenololA synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients.
BefunololUsed in the management of open angle glaucoma. PMID: 12480285.
BevantololFor the treatment of angina pectoris and hypertension.
BopindololFor the management of hypertension, edema, ventricular tachycardias, and atrial fibrillation.
BucindololBucindolol has been investigated in Heart Failure.
BufuralolBufuralol is a new, non-selective -adrenoceptor blocking agent.
BupranololUsed to manage hypertension and tachycardia. Also used to treat glaucoma.
CarteololA beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma.
CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
CloranololNot Annotated
EpanololEpanolol is an beta blocker.
EsatenololEsatenolol is a beta blocker.
EsmololA cardioselective beta-adrenergic blocker used for the short-term control of ventricular rate and heart rate in various types of tachycardia, including perioperative tachycardia and hypertension.
IndenololIndenolol is a drug of the beta-adrenergic blocker class.
LandiololLandiolol has been used in trials studying the treatment of Pharmacokinetics/Dynamics Study.
LevobetaxololUsed in the treatment of open-angle glaucoma and ocular hypertension [FDA Label].
LevobunololA beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
MepindololMepindolol is a 2-methyl derivative of pindolol. It is a beta blocker.
MetipranololA beta-adrenergic antagonist used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
NadololA non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension.
NebivololA beta blocking agent used to treat hypertension and aid in the management of heart failure.
OxprenololA non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety.
PenbutololA beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents.
PindololA beta adrenoceptor antagonist used to treat hypertension, edema, ventricular tachycardias, and atrial fibrillation.
PractololUsed in the emergency treatment of cardiac arrhythmias.
SotalolA methane sulfonanilide beta adrenergic antagonist used to treat life-threatening ventricular arrhythmias and to maintain sinus rhythm in atrial fibrillation or flutter.
TalinololTalinolol has been investigated for the basic science of Gastrointestinal Motility Disorder.
TertatololTertatolol is a beta blocker.
PaliperidoneAn atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
DapoxetineFor the treatment of premature ejaculation.
CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
EscitalopramA selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
LevomilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to treat major depressive disorder (MDD).
NefazodoneAn antidepressant used in the treatment of depression.
TrazodoneA serotonin uptake inhibitor used to treat major depressive disorder.
Fusidic acidA topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
GalantamineA cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
BuprenorphineA partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction.
BuspironeAn anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
BepridilFor the treatment of hypertension, and chronic stable angina (classic effort-associated angina).
FluvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Aripiprazole lauroxilAn antipsychotic used to treat schizophrenia in adults.
ZuclopenthixolAn antipsychotic indicated for the management of schizophrenia. The acuphase formulation is indicated for initial treatment of acute psychosis or exacerbation of psychosis, while the depot formulation is best for maintenance.
FesoterodineAn antimuscarinic agent used in the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency.
PitolisantAn antagonist and inverse agonist at the histamine H3 receptor that is used to treat narcolepsy in adults.
BrexpiprazoleA serotonin–dopamine activity modulator used in the treatment of major depressive disorder as an adjunct and schizophrenia.
EliglustatA glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers, based on the FDA-approved test.
AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
CevimelineA muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome.
ProchlorperazineA phenothiazine derivative used in the treatment of schizophrenia and anxiety and to relieve severe nausea and vomiting.
DarifenacinAn M3 muscarinic receptor blocker used to treat urinary incontinence.
NicergolineFor the treatment of senile dementia, migraines of vascular origin, transient ischemia, platelet hyper-aggregability, and macular degeneration.
DolasetronAn antinauseant and antiemetic used in chemotherapy and postoperatively.
MinaprineFor the treatment of depression
DonepezilAn acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia.
PhenforminFor the reatment of type II diabetes mellitus.
AlmotriptanA 5-HT1B/1D receptor agonist used to treat migraines.
ProcainamideA medication used to treat life threatening ventricular arrhythmias.
TolterodineA muscarinic receptor antagonist used to treat overactive bladder with urinary incontinence, urgency, and frequency.
ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
MoclobemideA monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder.
TiotropiumA long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
DiphenhydramineA H1 receptor antihistamine used in the treatment of seasonal allergies, and various allergic reactions including sneezing, runny nose, itchy/watery eyes, itching of nose or throat, pruritus, urticaria, insect bites/stings, and allergic rashes.
DebrisoquineFor the treatment of moderate and severe hypertension, either alone or as an adjunct, and for the treatment of renal hypertension.
GefitinibA tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
TerfenadineFor the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
MesoridazineA phenothiazine antipsychotic used to treat schizophrenia, organic brain disorders, alcoholism, and psychoneuroses.
MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
OxymorphoneAn opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies.
MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
DihydrocodeineAn opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
SertindoleUsed in the treatment of schizophrenia.
TesmilifeneIntended for the treatment of various forms of cancer.
RotigotineA non-selective dopamine agonist used for the treatment of Parkinson's Disease and Restless Leg Syndrome.
LisurideFor the management of Parkinson's Disease
TrabectedinAn alkylating agent approved for the treatment of unresectable or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma).
4-MethoxyamphetamineNot Available
SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker so it falls under the category...
TiclopidineA platelet aggregation inhibitor used in the prevention of conditions associated with thrombi, such as stroke and transient ischemic attacks (TIA).
AmoxapineA tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
IloperidoneAn atypical antipsychotic agent used for the acute treatment of schizophrenia in adults.
MetamfetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.
PipotiazineAn antipsychotic indicated for the management of chronic, non-agitated schizophrenic patients.
TamsulosinAn alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
TetrabenazineA vesicular monoamine transporter 2 (VMAT) inhibitor used for the management of chorea associated with Huntington's Disease.
TipranavirA protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
EletriptanA triptan used for the treatment of migraines.
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
AmprenavirA protease inhibitor used to treat HIV infection.
AprindineAprindine is a cardiac depressant used in arrhythmias.
AstemizoleA second generation antihistamine used to treat allergy symptoms.
BenzatropineAn anticholinergic drug used to treat Parkinson's disease (PD) and extrapyramidal symptoms, except tardive dyskinesia.
BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DoxazosinAn alpha-1 adrenergic receptor used to treat mild to moderate hypertension and urinary obstruction due to benign prostatic hyperplasia.
IdarubicinAn anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
PentamidineAn antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
PiperazineA medication used to treat roundworm and pinworm.
QuetiapineA psychotropic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.
RemoxiprideAn discontinued atypical antipsychotic selective for dopamine D2 receptors.
SimvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
YohimbineAn alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
VilazodoneAn antidepressant agent used for the treatment of major depressive disorder that targets the 5-HT transporter and 5-HT1A receptors.
RepinotanInvestigated for use/treatment in strokes, cerebral ischemia, and depression.
ClevidipineA dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
EnclomipheneNot Annotated
TapentadolAn opioid used to manage severe pain that has not responded to non-opioid medications, and for which opioid analgesic therapy is appropriate.
MirabegronA beta-3 adrenergic agonist used to treat urge urinary incontinence, urinary frequency and urgency associated with overactive bladder (OAB).
PonatinibA kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML).
AlogliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
NetupitantAn antiemetic agent used in combination with palonosetron to prevent acute and delayed vomiting and nausea caused by chemotherapy.
UmeclidiniumA long-acting muscarinic antagonist used as a long-term maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD).
CariprazineAn atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
EsmirtazapineInvestigated for use/treatment in insomnia and sleep disorders.
Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
VernakalantAn antiarrhythmic medication used to treat patients with atrial fibrillation.
ValbenazineA vesicular monoamine transporter 2 inhibitor used to treat tardive dyskinesia.
PerospironeFor the treatment of schizophrenia and acute cases of bipolar mania.
RupatadineA selective histamine H1 receptor antagonist and platelet activating factor (PAF) antagonist used to treat allergic rhinitis.
LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
OpiumA medication used to treat moderate to severe pain.
IbrutinibAn antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
IpecacAn emetic agent used to induce vomiting in poisoning.
Lysergic acid diethylamideDebate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by...
EncorafenibA kinase inhibitor used to treat unresectable or metastatic melanoma with specific mutations.
LorpiprazoleIn 2016, lorpiprazole was classified in the "Chemical structure-related drug-like criteria of global approved drugs" as an antipsychotic and anxiolytic. An antipsychotic is a medication used to treat a state...
DextropropoxypheneAn opioid analgesic used to treat mild to moderate pain.
ApraclonidineAn alpha adrenergic agonist used to treat raised intraocular pressure.
MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used...
DacomitinibA medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution.
RevefenacinAn anticholinergic agent used to treat COPD.
LisdexamfetamineA central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders.
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
DextroamphetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
MeclizineA histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
DexchlorpheniramineDexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjuctive therapy for allergic and anaphylactic...
SolifenacinA muscarinic antagonist with antispasmodic properties used to treat urge urinary incontinence, urgency, and urinary frequency associated with an overactive bladder.
QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
ButyrfentanylA methylated fentanyl analog with no clinical indications but is commonly used as a recreational drug.
MidodrineAn alpha-adrenergic antagonist used to treat orthostatic hypotension.
LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
CiclesonideA glucocorticoid used in the symptomatic relief of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents.
CannabidiolAn active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer.
AzimilideInvestigated for use/treatment in arrhythmia and atrial fibrillation.
5-methoxy-N,N-dimethyltryptamine5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug,...
NabiximolsIn Canada, Sativex has received a Notice of Compliance (NOC) for use as an as adjunctive treatment for symptomatic relief of spasticity in patients with multiple sclerosis (MS) who have...
EnfluraneA halogenated inhalational anesthetic agent used for the induction and maintenance of anesthesia and for analgesia during labor and delivery.
AnilineAniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor...
EthosuximideAn anticonvulsant used to treat petit mal seizures.
NilvadipineFor the management of vasospastic angina, chronic stable angina and hypertension.
TrimethadioneAn anticonvulsant agent indicated for the control of treatment-refractory petit mal seizures.
DichlorobenzeneDichlorobenzene refers to any of, or a mixture of, three isomers consisting of benzene in which two of the hydrogen atoms are replaced by chlorine atoms: ortho-, meta-, and paradichlorobenzene....
FelbamateAn anticonvulsant used to treat severe epilepsy.
NicotinamideAn ingredient found in a variety of cosmetic products.
ZafirlukastA leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma.
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
IrbesartanAn angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
GlipizideA sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
PhenytoinAn anticonvulsant drug used in the prophylaxis and control of various types of seizures.
RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
PhenprocoumonUsed for the prevention and treatment of thromboembolic disease including venous thrombosis, thromboembolism, and pulmonary embolism as well as for the prevention of ischemic stroke in patients with atrial fibrillation...
(S)-WarfarinWarfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in...
FluindioneFluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for...
LynestrenolLynestrenol has been used in trials studying the basic science of Transsexualism and Gender Dysphoria.
EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
VoriconazoleA triazole compound used to treat fungal infections.
DicoumarolFor decreasing blood clotting. Often used along with heparin for treatment of deep vein thrombosis.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
AcetohexamideUsed in the management of diabetes mellitus type 2 (adult-onset).
GliquidoneUsed in the treatment of diabetes mellitus type 2.
GlisoxepideFor the treatment of diabetes mellitus type 2.
GlibornurideGlibornuride is a sulfonylurea-type anti-diabetic drug.
CarbutamideNot Annotated
MetahexamideNot Annotated
FosphenytoinAn antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
AlprazolamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
BexaroteneA retinoid drug used for cutaneous manifestations of T-cell lymphoma in patients who have not responded well to previous systemic therapy.
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
LacosamideAn antiepileptic drug used to treat partial onset seizures in adults.
PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
HydromorphoneAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
ParamethadioneUsed for the control of absence (petit mal) seizures that are refractory to treatment with other medications.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
SulfamethoxazoleAn oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract.
Candesartan cilexetilAn angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
Arachidonic AcidAn unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides....
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
MestranolA synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
ValsartanAn angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
ThalidomideA medication used to treat newly diagnosed multiple myeloma and erythema nodosum leprosum.
VicrivirocInvestigated for use/treatment in HIV infection and viral infection.
LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
TrimethoprimAn antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
ZopicloneA nonbenzodiazepine hypnotic used for the short-term management of insomnia.
SitaxentanInvestigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
LicofeloneFor the management of osteoarthritis.
ZaltoprofenA non-steroidal anti-inflammatory drug approved for use in Japan in 1993.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
PioglitazoneA thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus.
ProguanilA medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
QuazepamA long -acting benzodiazepine used to manage insomnia.
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
IndisulamInvestigated for use/treatment in lung cancer.
NiclosamideFor the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used...
ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
VismodegibA hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.
TreprostinilA prostacyclin vasodilator for the treatment of pulmonary arterial hypertension to relieve exercise associated symptoms and to prevent clinical deterioration after stopping epoprostenol.
PitavastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
CabozantinibA tyrosine kinase inhibitor used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and medullary thyroid cancer.
OlodaterolA long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
LesinuradA uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
CandesartanCandesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is available as a prodrug in the form of candesartan cilexetil.
PiperaquineFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
Medical CannabisThe use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical...
XimelagatranFor the treatment of acute deep vein thrombosis.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
CoumarinNot Available
TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DesogestrelA synthetic progestin used in contraception, often in combination with ethinyl estradiol.
SiponimodA medication used to treat relapsing multiple sclerosis.
ErdafitinibA fibroblast growth factor receptor tyrosine kinase inhibitor used to treat locally advanced or metastatic urothelial carcinoma.
DexibuprofenFor more information, refer to ibuprofen.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
CapravirineInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
CarisoprodolA centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DexrabeprazoleNot Annotated
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
BarbitalA long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
MethohexitalAn anesthetic used to induce deep sedation.
PentobarbitalA barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
ThiopentalA barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
MethsuximideA succinimide anticonvulsant that increases the seizure threshold. Primarily used for childhood absence seizures. Functions by suppressing paroxysmal spike-and-wave patterns associated with lapses of consciousness in absence seizures.
LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
St. John's WortAn herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
LorlatinibAn anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
EtizolamIndicated for the treatment of generalized anxiety disorder with depression, panic disorder and insomnia.
DexlansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
FedratinibFedratinib is indicated to treat adults with primary or secondary myelofibrosis that is either intermediate-2 or high risk.
CerivastatinA statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events.
RepaglinideA antihyperglycemic used to improve glycemic control in diabetes.
PaclitaxelA taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.
AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
BalaglitazoneBalaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
CiglitazoneDeveloped by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in...
LobeglitazoneLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use...
NetoglitazoneNetoglitazone (MCC-555) is a hypoglycemic agent.
RivoglitazoneRivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co.
OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
AtorvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
DiethylstilbestrolUsed in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery.
EthinylestradiolAn estradiol used as a contraceptive.
SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
EszopicloneA sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep.
CabazitaxelAn antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
HalofantrineAn antimalarial used for the treatment of severe malaria.
MorphineAn opioid agonist used for the relief of moderate to severe acute and chronic pain.
SulfadiazineA sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
TazaroteneAn acetylenic retinoid used to treat fine wrinkles, mottled pigmentation of the skin, acne vulgaris, and plaque psoriasis.
BeraprostFor the treatment of pulmonary hypertension.
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
Mycophenolate mofetilAn inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants.
SelexipagA non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
RiociguatA stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.
OdanacatibInvestigated for use/treatment in osteoporosis .
BrigatinibAn anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
ApalutamideAn androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer.
NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
GlasdegibA sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
LovastatinAn HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke.
IndinavirA protease inhibitor used to treat HIV infection.
NisoldipineA calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
MidazolamA short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders.
AlfentanilAn opioid agonist used to induce and maintain anesthesia, as well as an analgesic.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
TacrolimusA calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
SirolimusAn immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis.
TriazolamA benzodiazepine used for short term treatment of insomnia.
TelithromycinAn ketolide used to treat community acquired pneumonia of mild to moderate severity.
FelodipineA calcium channel blocker used to treat hypertension.
NitrendipineFor the treatment of mild to moderate hypertension
ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
ErythromycinA macrolide antibiotic used to treat and prevent a variety of bacterial infections.
CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
AzithromycinA macrolide antibiotic used to treat a variety of bacterial infections.
TelaprevirAn NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.
BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
IsavuconazoleIndicated for patients 18 years of age and older for the treatment of invasive aspergillosis [FDA Label]. Indicated for patients 18 years of age and older for the treatment of...
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
TemsirolimusA antineoplastic agent used in the treatment of renal cell carcinoma (RCC) that works by inhibiting mTOR.
AvanafilA phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction.
ConivaptanAn antidiuretic hormone inhibitor used to raise serum sodium levels.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
EbastineEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
EverolimusA mammalian target of rapamycin (mTOR) kinase inhibitor used to treat various types of malignancies.
LomitapideA microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke.
NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
EplerenoneAn aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
LurasidoneAn atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
TolvaptanA selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia.
AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
ColchicineAn alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
RivaroxabanA factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
MethysergideAn ergot alkaloid used for the prophylaxis of migraine and cluster headaches.
TianeptineUsed primarily in the treatment of major depressive disorder and anxiety . It is currently being studied for fibromyalgia pain treatment .
BromocriptineA dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome.
CabergolineA dopamine receptor agonist used for the treatment of hyperprolactinemic conditions due to various causes.
DihydroergocornineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
DihydroergocristineAn ergot alkaloid used to delay progressive mental decline in conditions like Alzheimer's.
DihydroergocryptineNot Annotated
DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
Ergoloid mesylateA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
ErgometrineAn ergot alkaloid used for the treatment of postpartum haemorrhage and post abortion hemorrhage in patients with uterine atony.
ErgotamineA alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
MethylergometrineAn ergot alkaloid used to prevent and control uterine atony and hemorrhage before and after delivery.
TergurideNot Annotated
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
AlfuzosinAn alpha-1 adrenergic antagonist used in the management of benign prostatic hypertrophy (BPH).
FostamatinibA spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
FluticasoneFluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is...
LacidipineIndicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .
AllylestrenolAllylestrenol was designed to be used for miscarriage prevention, prevention of premature labour and has been investigated for possible use in men for treatment for benign prostatic hyperplasia.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Cortisone acetateA steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
DeflazacortA corticosteroid used to treat Duchenne muscular dystrophy.
DienogestAn oral progestin used for the treatment of endometriosis as monotherapy or contraception in combination with ethinylestradiol.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Dexamethasone isonicotinateDexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
DrospirenoneA progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
EtonogestrelA long-acting synthetic derived progestin contraceptive used in various devices such as contraceptive rings and intradermal implants.
FlunisolideAn inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma.
FluocortoloneFluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
FluorometholoneAn ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye.
Fluticasone furoateAn inhaled corticosteroid that can be used as maintenance treatment of asthma and/or chronic obstructive pulmonary disease (COPD) depending on the product. Also available as a nasal spray to manage symptoms of allergic rhinitis.
Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Hydrocortisone aceponateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone acetateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
Hydrocortisone butyrateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone cypionateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone phosphateFor the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many...
Hydrocortisone probutateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydrocortisone valerateA corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses.
Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
LevonorgestrelA progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.
LevothyroxineA synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
Medroxyprogesterone acetateA progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
NorethisteroneA synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis.
NorgestimateA progesterone used as a contraceptive and to treat acne vulgaris.
NorgestrelA progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
ParamethasoneFor the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary...
PrasteroneA steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
4-hydroxycoumarinNot Available
ClorindioneClorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
DiphenadioneNot Annotated
Ethyl biscoumacetateEthyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
AzelnidipineFor the treatment of hypertension.
BarnidipineIndicated for the treatment of mild to moderate essential hypertension and management of chronic stable angina.
BencyclaneA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
BenidipineBenidipine is a potent and long-lasting drug indicated for the treatment of cardiovascular diseases such as hypertension, renoparenchymal hypertension and angina pectoris.
CarboxyamidotriazoleCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
CaroverineNot Annotated
CilnidipineCilnidipine is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnidipine has been...
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
DarodipineDarodipine is a calcium channel blocker.
DexniguldipineNot Annotated
DexverapamilNot Annotated
DotarizineInvestigated for use/treatment in migraine and cluster headaches.
EfonidipineFor the treatment of hypertension.
EmopamilPrevents renal injury after warm & cold ischemia.
EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
FendilineFendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.
Fish oilA source of essential fatty acids used as a source of calories in parenteral nutrition and as a dietary supplement.
FluspirileneAn antipsychotic agent used in the treatment of schizophrenia.
GallopamilGallopamil has been used in trials studying the treatment of Asthma.
IsradipineA dihydropyridine calcium channel blocker used for the treatment of hypertension.
LamotrigineA phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder.
LercanidipineFor the treatment of Hypertension, management of angina pectoris and Raynaud's syndrome
LidoflazineNot Annotated
LomerizineUsed to treat migraines.
ManidipineFor the treatment of hypertension.
LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
MibefradilFor the treatment of angina and high blood pressure.
NaftopidilNaftopidil has been investigated for the treatment of Disorder of Urinary Stent.
NiludipineNiludipine is a calcium channel blocker.
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
NimodipineA calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm.
NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
NiguldipineNiguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
OtiloniumNot Annotated
PenfluridolNot Annotated
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
TerodilineNot Annotated
TetrahydropalmatineTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
TetrandrineNot Annotated
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
SeletracetamInvestigated for use/treatment in epilepsy.
VinpocetineVinpocetine has been investigated for the treatment of Epilepsy.
WIN 55212-2WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. It...
IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
IxabepiloneA microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.
RifampicinAn antibiotic used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and in combination with other antibacterials to treat latent or active tuberculosis.
RifabutinAn antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
RifapentineAn antibiotic agent used in the treatment of pulmonary tuberculosis.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
RegorafenibA kinase inhibitor used to treat patients with metastatic colorectal cancer, unresectable, locally advanced, or metastatic gastrointestinal stromal tumors, and hepatocellular carcinoma.
IvabradineA HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.
VemurafenibA kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation.
CrizotinibA receptor tyrosine kinase inhibitor used to treat metastatic non-small cell lung cancer (NSCLC) where the tumors have been confirmed to be anaplastic lymphoma kinase (ALK), or ROS1-positive.
IsavuconazoniumA triazole antifungal used for the treatment of invasive aspergillosis and mucormycosis.
DofetilideA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
ReboxetineFor the treatment of clinical depression.
VindesineA vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
ToremifeneA first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
VinblastineA vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.
EnalaprilA prodrug of an ACE inhibitor used to treat hypertension and congestive heart failure.
ClofibrateA fibric acid derivative used to treat hypertriglyceridemia and high cholesterol.
MebendazoleA benzimidazole anthelmintic used to treat helminth infections.
ModafinilA stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
RoxithromycinUsed to treat respiratory tract, urinary and soft tissue infections.
FentanylAn opioid analgesic used in anesthesia, for breakthrough cancer pain, or round the clock pain management.
MifepristoneA cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation.
GranisetronA 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.
TiagabineAn antiepileptic used to treat partial seizures.
CocaineAn ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
ParicalcitolA vitamin D analog used to treat hyperparathyroidism associated with stage 3 or greater chronic kidney disease.
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
ZaleplonA sedative used for short term treatment of insomnia in adults.
ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
DoxorubicinA medication used to treat various cancers and Kaposi's Sarcoma.
BusulfanAn alkylating agent used to treat chronic myelogenous leukemia.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
ClonazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures.
SibutramineA norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
DutasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) in adult males by inhibiting 5-alpha reductase.
ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
EstazolamA benzodiazepine used for the short-term management of insomnia.
FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
LevacetylmethadolFor the treatment and management of opiate dependence. It is sometimes used to treat severe pain in terminal patients.
RetapamulinA topical antibiotic agent used for the treatment of impetigo caused by methicillin-susceptible Staphylococcus aureus or Streptococcus pyogenes.
SunitinibA receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST).
PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
RimonabantFor use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated...
LaquinimodInvestigated for use/treatment in multiple sclerosis.
DocetaxelA taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
AmbrisentanA selective type A endothelin receptor antagonist used to treat primary pulmonary arterial hypertension and pulmonary arterial hypertension based on diagnostic classifications.
BisoprololA beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
Clorazepic acidA benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal.
DantroleneA direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
GuanfacineAn alpha-2A adrenergic receptor agonist used to treat ADHD.
MefloquineAn antimalarial agent used as a schizonticidal agent.
NilotinibA kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.
SilodosinAn alpha-1 adrenergic receptor antagonist used to treat symptoms associated with benign prostatic hyperplasia (BPH).
SpiramycinA macrolide antimicrobial agent used in the treatment of various bacterial infections.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
SufentanilAn opioid used to induce and maintain anesthesia, to act as an analgesic in labor and delivery, and to treat severe, acute pain.
BicalutamideAn androgen receptor inhibitor used to treat Stage D2 metastatic carcinoma of the prostate.
SulfinpyrazoneA platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
AdinazolamFor the treatment of anxiety and status epilepticus.
VanoxerineNot Available
CholecalciferolA form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
LumefantrineAn antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
AmbroxolAmbroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
BezafibrateA lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
CarbinoxamineA first generation antihistamine used to treat allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic reactions, and mild allergic reactions.
CephalexinA first generation cephalosporin used to treat certain susceptible bacterial infections.
ClofazimineA riminophenazine antimycobacterial used to treat leprosy.
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
DaunorubicinAn anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
DisulfiramA carbamate derivative used to treat alcohol addiction.
EstramustineAn antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
FamciclovirA nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
FenofibrateA peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia.
FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
ImiquimodA toll-like receptor 7 agonist used to treat non hyperkeratotic, non hypertrophic actinic keratosis, basal cell carcinoma, genital or perianal warts, and condyloma acuminata.
QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
MethaqualoneFor the treatment of insomnia, and as a sedative and muscle relaxant.
NitrazepamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures.
OlopatadineA histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
PrazepamFor the treatment of anxiety disorders.
TasosartanTasosartan is infrequently in the treatment of hypertension and heart failure.
ThiotepaAn alkylating agent used to prevent graft rejection in stem cell transplantation and to treat a variety of malignancies including certain types of adenocarcinoma and superficial bladder carcinomas.
TroleandomycinFor the treatment of bacterial infection.
ZomepiracZomepirac was indicated for the management of mild to severe pain.
KetazolamA long-acting benzodiazepine used to manage anxiety and insomnia.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
IvacaftorA cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used alone or in combination products to treat cystic fibrosis in patients who have specific genetic mutations that are responsive to the medication.
IndacaterolAn inhaled long-acting beta-2 adrenergic agonist used to relax bronchial smooth muscle and improve symptoms and airflow obstruction caused by Chronic Obstructive Pulmonary Disease (COPD) and moderate to severe asthma.
Chenodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis.
PinacidilPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood...
PimecrolimusA topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons.
Brentuximab vedotinA CD30-directed antibody-drug conjugate used to treat various types of lymphoma.
VandetanibAn antineoplastic kinase inhibitor used to treat symptomatic or progressive medullary thyroid cancer in patients with unresectable locally advanced or metastatic disease.
RuxolitinibA kinase inhibitor used to treat various types of myelofibrosis, polycythemia vera in patients who have not responded to or cannot tolerate hydroxyurea, and to treat graft-versus-host disease in cases that are refractory to steroid treatment.
AbirateroneAn antiandrogen used in the treatment of prostate cancer.
TofacitinibA Janus kinase (JAK) inhibitor used to treat rheumatoid and psoriatic arthritis, and ulcerative colitis. It is not recommended to be combined with biologic therapies or potent immunosuppressants like cyclosporine or azathioprine.
BosutinibAn antineoplastic agent used for the treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) in adults with inadequate clinical response to other treatments.
BedaquilineA diarylquinoline antimycobacterial used in combination with other antibacterials to treat pulmonary multidrug resistant tuberculosis (MDR-TB).
CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
Trastuzumab emtansineAn antineoplastic agent and antibody-drug conjugate used to treat HER2-overexpressing breast cancer.
Taurochenodeoxycholic acidTaurochenodeoxycholic acid is likely indicated as a choleretic and cholagogue. It is also being investigated for its role in inflammation and cancer therapy.
MacitentanAn endothelin receptor antagonist used to manage pulmonary arterial hypertension to delay disease progression.
OlaparibA chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.
PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
VilanterolA long-acting beta2-adrenergic agonist used in combination with other bronchodilators for the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.
AliskirenA direct renin inhibitor used to manage hypertension.
ElvitegravirAn antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
RolapitantA neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.
FlibanserinA 5-HT receptor modulator used for the treatment of selected premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD).
DaclatasvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
SonidegibAn antineoplastic agent used for the treatment of locally advanced recurrent basal cell carcinoma (BCC) following surgery and radiation therapy, or in cases where surgery or radiation therapy are not appropriate.
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Synthetic Conjugated Estrogens, AA mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal atrophy and dyspareunia.
Synthetic Conjugated Estrogens, BA mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal dryness.
VenetoclaxA BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Esterified estrogensA female hormone used to treat conditions related to estrogen deficiency and moderate to severe vasomotor menopausal symptoms in women.
SafinamideA MAO-B inhibitor used as an add-on treatment to levodopa/carbidopa for Parkinson's disease during "off" episodes.
GrazoprevirAn antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
ImidafenacinUsed in the treatment of overactive bladder [FDA Label].
NeratinibA protein kinase inhibitor used to treat breast cancer that over expresses the HER2 receptor.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
ElbasvirAn antiviral and NS5A inhibitor used to treat hepatitis C infections.
CopanlisibA medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments.
AbemaciclibA medication used to treat HR+ HER2- advanced or metastatic breast cancer.
BaricitinibA Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist.
MacimorelinA medication used to treat adult growth hormone deficiency.
BlonanserinUsed for the treatment of schizophrenia .
Testosterone propionateA slow-release anabolic steroid no longer used commonly for the treatment of androgen deficiency or promotion of anabolic effects on muscles.
BictegravirAn integrase inhibitor used to treat HIV infections.
TezacaftorA medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis.
TocopherolTocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
VinflunineA vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
TocofersolanA derivative of alpha tocopherol used to treat vitamin E deficiencies.
DelamanidAn antibiotic used to treat multidrug resistant tuberculosis.
FosnetupitantA medication used in combination with others to prevent chemotherapy associated nausea and vomiting.
Dihydro-alpha-ergocryptineA nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
MidecamycinMidecamycin was used for the treatment of infections in the oral cavity, upper and lower respiratory tracts and skin and soft tissue infections. The alone use of midecamycin was mainly...
Segesterone acetateSegesterone acetate in combination with ethinyl estradiol is indicated for use by females of reproductive potential to prevent pregnancy as a combination hormonal contraceptive (CHC). It induces contraception for thirteen...
CobicistatA CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
LinagliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
CobimetinibAn antineoplastic agent and selective inhibitor of the mitogen-activated extracellular kinase (MEK) pathway used to treat unresectable or metastatic melanoma.
OsimertinibA tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma.
CeritinibAn antineoplastic kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) in patients with inadequate clinical response or intolerance to crizotinib.
RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
NintedanibA triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
RoflumilastA selective phosphodiesterase 4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) associated with a history of exacerbations and chronic bronchitis.
SuvorexantA orexin receptor antagonist used to treat insomnia that is characterized by difficulties with sleep onset and/or sleep maintenance.
VorapaxarA platelet aggregation inhibitor used to reduce thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD).
IdelalisibAn antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL).
PranlukastUsed as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists.
EravacyclineA tetracycline antibiotic used to treat complicated intra-abdominal infections.
FosaprepitantAn antiemetic drug used in combination with other antiemetic agents for the prevention of acute and delayed nausea and vomiting caused by chemotherapy.
CethromycinA ketolide antibiotic with broad-spectrum activity against Gram-positive, Gram-negative, and atypical bacteria that may be useful for treating several conditions including community-acquired pneumonia, inhalation anthrax, plague, and tularemia.
DoravirineA non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.
DuvelisibAn inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
IvosidenibAn isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia with a susceptible mutation.
3,5-diiodothyropropionic acidDITPA has been investigated in Congestive Heart Failure.
5-androstenedione5-androstenedione is a prohormone of testosterone. In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. Thus 5-androstenedione is a controlled substance, and its...
AlclometasoneA topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses.
AldosteroneA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
AmcinonideA topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses.
AndrostenedioneA delta-4 C19 steroid that is produced not only in the testis, but also in the ovary and the adrenal cortex. Depending on the tissue type, androstenedione can serve as...
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
ClobetasolClobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.
Clobetasol propionateA corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis.
ClobetasoneA corticosteroid used to treat dry eyes, eczema, and dermatitis.
CorticosteroneAn adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)
CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Cyproterone acetateA steroid used in combination with ethinyl estradiol to treat women with severe acne and symptoms of androgenization. Also used alone at much higher doses for palliative treatment of patients with prostate cancer
NomegestrolNomegestrol is an ingredient in the EMA-authorised product Zoely.
Nomegestrol acetateNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
DesonideA topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Desoxycorticosterone acetateNot Annotated
Desoxycorticosterone pivalateExamined for treatment of adrenocortical insufficiency especially in multiple sclerosis, congenital cerebral palsy, polyarteritis nodosa, and rheumatoid arthritis. Currently only approved in treating cats and dogs for the treatment of...
DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DifluprednateA topical corticosteroid used for the symptomatic treatment of inflammation and pain associated with ocular surgery.
DydrogesteroneUsed to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency. Also used to prevent natural abortion in patients who have a history...
EquileninEquilenin is an estrogenic steroid produced by horses. It has a total of five double bonds in the A- and B-ring. High concentration of equilenin is found in the urine...
EquilinFor the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and...
EtynodiolEtynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers...
Ethynodiol diacetateAn oral contraceptive used to prevent pregnancy.
FludrocortisoneA mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.
FlumethasoneA corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
FluocinonideA high potency corticosteroid commonly used topically for a number of inflammatory skin conditions.
FluprednideneFluprednidene is a corticosteroid.
FluprednisoloneA synthetic glucocorticoid with anti-inflammatory properties.
FlurandrenolideA corticosteroid used to treat corticosteroid-responsive dermatoses.
GestodeneGestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol...
HalcinonideA corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
HE3286For the treatment of rheumatoid arthritis and type 2 diabetes.
Hydrocortisone succinateA corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
HydroxyprogesteroneNot Annotated
LiotrixMay be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic...
Loteprednol etabonateA corticosteroid used to treat allergic conjunctivitis as well as inflammation and pain after ocular surgery.
MedrogestoneA progestin used as an adjunct to control secondary amenorrhea and dysfunctional bleeding in adolescent and adult females, and treat endometrial shedding in menopausal women.
MedrysoneA topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions.
Megestrol acetateA progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
MelengestrolMelengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.
MeprednisoneNot Annotated
MometasoneA corticosteroid with no indications.
Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
NorelgestrominA progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception.
NorethynodrelA synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it...
PrednicarbateA medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions.
PrednylidenePrednylidene is an experimental systemic glucocorticoid.
PregnenoloneA 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
PromegestoneNot Annotated
RimexoloneA glucocorticoid used to treat inflammation of the eye.
TrilostaneUsed in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible.
AtovaquoneAn antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
GestrinoneEndometriosis with or without accompanying sterility. Treatment is limited to a single course of 6 months duration per lifetime [L1699, L1700].
ChlormadinoneNot Annotated
QuingestanolNot Annotated
DemegestoneDemegestone is a progesterone receptor agonist that was previously used to treat luteal insufficiency. It was previously marketed in France as Lutionex, but has since been discontinued.
AgmatineAgmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,...
GemfibrozilA lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia.
IndalpineIndalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse...
MilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
AranidipineAranidipine has been used for many years to treat angina pectoris and hypertension.
PyrazinamideAn antituberculosis agent used as a component of tuberculosis (TB) treatment.
LenvatinibA receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma.
RufinamideAn antiepileptic drug used as adjunctive therapy to treat seizures associated with Lennox-Gastaut Syndrome (LGS).
LorazepamA long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
9-aminocamptothecinAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
MethylprednisoneMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
LarotrectinibA kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments.
GilteritinibAn AXL receptor tyrosine kinase inhibitor used to treat relapsed or refractory acute myeloid leukemia.
BenzodiazepineBenzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary...
BrotizolamBrotizolam is indicated for 2-4 weeks in the treatment of severe or debilitating insomnia.
Vitamin DAn ingredient found in a variety of supplements and vitamins.
7-ethyl-10-hydroxycamptothecinInvestigated for use/treatment in colorectal cancer.
TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
PrucaloprideA P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat coronary revascularization, and stent thrombosis (ST).
DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
PhentermineA sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
TenofovirTenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the...
AlpelisibAlpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor...
SelinexorSelinexor is indicated for the treatment of relapsed or refractory multiple myeloma in combination with dexamethasone.[label] Patients must have received at least 4 prior therapies and have disease which is...
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Vitamin EAn antioxidant vitamin used in many skin creams and multivitamin preparations.
IsotretinoinA retinoid used to treat severe recalcitrant acne.
RivastigmineA cholinesterase inhibitor used to treat mild to moderate dementia in Alzheimer's and Parkinson's.
LevocetirizineAn H1-receptor antagonist used to treat symptoms associated with chronic allergic rhinitis and uncomplicated cases of chronic idiopathic urticaria.
PexidartinibAn antitumor agent that is used for the treatment of rare disease tenosynovial giant cell tumors (TGCT) by inhibiting colony-stimulating factor 1 and its receptor.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
PretomanidPart of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.
HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
EntrectinibEntrectinib is indicated for the treatment of metastatic ROS1-positive non-small cell lung cancer in adults. Entrectinib is also indicated in adults and children over 12 years old for the treatment...
TranylcypromineA monoamine oxidase inhibitor used to treat major depressive disorder.
LefamulinA pleuromutilin antibacterial used to treat community-acquired bacterial pneumonia (CABP).
FlucloxacillinA narrow spectrum penicillin antibiotic that exerts specific activity against Gram positive organisms in skin and soft tissue infections, except those caused by methicillin resistant staphylococcus aureus (MRSA).
MexazolamA benzodiazepine indicated to treat anxiety with or without psychoneurotic conditions.
Calanolide AFor use in combination treatment of HIV infection (AIDS).
RifalazilInvestigated for use/treatment in atherosclerosis, bacterial infection, and peripheral vascular disease.
Polatuzumab vedotinThis medication is indicated to treat adults with relapsed or refractory diffuse large B-cell lymphoma in combination with bendamustine and rituximab that has returned of progressed after 2 or more...
LevamlodipineA calcium channel blocker used to treat hypertension.
Fluprednisolone acetateNot Annotated
Baloxavir marboxilA polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
TenapanorAn NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
AnastrozoleA competitive, selective, non-steroidal aromatase inhibitor used as adjuvant therapy for the treatment of hormone receptor-positive breast cancer in postmenopausal women.
TrifaroteneA topical retinoid indicated for the treatment of acne vulgaris.
ElexacaftorA small molecule CFTR corrector used in combination with tezacaftor and ivacaftor for the treatment of cystic fibrosis patients with one F508del-CFTR mutation.
MitoxantroneA chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
FomepizoleAn inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.
IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
TirapazamineFor the treatment of head and neck cancer.
DalfampridineA potassium channel blocker used for the improvement of motor function in patients with multiple sclerosis (MS).
FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19.
N-Methyl-N-(Methylbenzyl)FormamideNot Available
1,2-dichlorobenzene1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
N,N-dimethylformamideNot Available
NilutamideAn antineoplastic hormone used to treat prostate cancer.
OxiconazoleA topical antifungal used to treat a variety of dermatophyte infections.
Prednisolone acetateA glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions.
HydroxyzineAn antihistamine used to treat anxiety and tension associated with psychoneuroses, as well as allergic conditions such as pruritus and chronic urticaria.
ZanubrutinibA kinase inhibitor used to treat mantle cell lymphoma, a type of B-cell non-Hodgkin lymphoma, in adults who previously received therapy.
VoxelotorA drug used to inhibit the polymerization of hemoglobin S, preventing the painful and sometimes lethal vaso-occlusive crises associated with sickle cell disease.
CenobamateA small molecule drug indicated to treat partial onset seizures in adults.
Enfortumab vedotinAn antibody-drug conjugate comprised of a fully human monoclonal antibody and microtubule-disrupting chemotherapeutic agent used in the treatment of advanced or metastatic urothelial cancer.
Trastuzumab deruxtecanAn antibody used to treat certain types of unresectable or metastatic HER-2 positive breast cancer.
LemborexantA dual orexin antagonist indicated for the treatment of sleep-onset and/or sleep maintenance insomnia.
DarolutamideAn androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer.
LumateperoneA novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia.
UpadacitinibAn oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis in adult patients who did not respond well to methotrexate.
UbrogepantAn oral CGRP antagonist used in the acute treatment of migraine with or without aura.
AvapritinibA selective tyrosine kinase inhibitor being investigated for the treatment of multidrug resistant gastrointestinal tumors.
TazemetostatA methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection.
RimegepantAn oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults.
UmifenovirA dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses.
OsilodrostatAn oral inhibitor of cortisol synthesis used to treat Cushing's disease by normalizing hypercortisolism.
Norethindrone enanthateNot Annotated
OzanimodA sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD).
SelumetinibA MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN).
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
TucatinibA kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer.
PemigatinibA kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients.
RemdesivirA nucleoside analog used to treat RNA virus infections including COVID-19.
AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
AcalabrutinibA Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma.
CapmatinibA kinase inhibitor targeting c-Met receptor tyrosine kinase in the treatment of non-small cell lung cancer with MET exon 14 skipping.
AlectinibA kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
CapecitabineA nucleoside metabolic inhibitor indicated to treat colon, colorectal and breast cancer.
SelpercatinibA RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations.
RipretinibA kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST).
ApomorphineA morphine derivative D2 dopamine agonist used to treat hypomobile "off" episodes of advanced Parkinson's disease.
Betamethasone phosphateA fast acting ester prodrug of a corticosteroid used to treat inflammatory conditions.
LurbinectedinA chemotherapeutic DNA alkylating agent used in the treatment of metastatic small-cell lung cancer.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
FenfluramineFenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
FostemsavirAn antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein.
AbametapirA pediculicide metalloproteinase used topically in the treatment of head lice infection.
RisdiplamAn oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA).
OliceridineA biased opioid agonist indicated for the management of severe acute pain in adult patients. Through preferential activation of G-protein-coupled signalling pathways, oliceridine provides analgesic effect with a comparable or improved safety profile over conventional opioid agonists.
PralsetinibA RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer.
Drugs & Drug Targets
DrugTargetType
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
CaffeineAdenosine receptor A1target
CaffeinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
CaffeineAdenosine receptor A2atarget
CaffeineCytochrome P450 1A2enzyme
CaffeineRyanodine receptor 1target
CaffeineCytochrome P450 3A4enzyme
CaffeineCytochrome P450 2E1enzyme
CaffeineCytochrome P450 2C8enzyme
CaffeineCytochrome P450 2C9enzyme
CaffeineCytochrome P450 1A1enzyme
CaffeineCytochrome P450 1B1enzyme
CaffeineCytochrome P450 2D6enzyme
CaffeineCyclic nucleotide phosphodiesterasetarget
CaffeineDNA-dependent protein kinase catalytic subunittarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformtarget
CaffeinePhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformtarget
CaffeineInositol 1,4,5-trisphosphate receptortarget
CaffeineSerine-protein kinase ATMtarget
CaffeineATP-binding cassette sub-family G member 2transporter
CaffeineAdenosine receptor A2btarget
CaffeineAdenosine receptor A3target
CaffeinePhosphodiesterase enzymestarget
AnagrelidecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AnagrelideCytochrome P450 1A2enzyme
RopiniroleDopamine D2 receptortarget
RopiniroleDopamine D3 receptortarget
RopiniroleDopamine D4 receptortarget
RopiniroleCytochrome P450 1A2enzyme
RopiniroleAlpha adrenergic receptortarget
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
LidocaineSodium channel protein type 5 subunit alphatarget
LidocaineSodium channel protein type 10 subunit alphatarget
LidocaineEpidermal growth factor receptortarget
LidocaineSodium channel protein type 9 subunit alphatarget
LidocaineCytochrome P450 1A2enzyme
LidocaineCytochrome P450 2D6enzyme
LidocaineCytochrome P450 3A4enzyme
LidocaineCytochrome P450 3A5enzyme
LidocaineCytochrome P450 3A7enzyme
LidocaineSolute carrier family 22 member 5transporter
LidocaineP-glycoprotein 1transporter
LidocaineCytochrome P450 2A6enzyme
LidocaineCytochrome P450 2B6enzyme
LidocaineCytochrome P450 2C8enzyme
LidocaineCytochrome P450 2C9enzyme
LidocaineSodium channel protein type 4 subunit alphatarget
LidocaineAlpha-1-acid glycoprotein 1target
LidocaineAlpha-1-acid glycoprotein 2target
Conjugated estrogensEstrogen receptor alphatarget
Conjugated estrogensCytochrome P450 3A4enzyme
Conjugated estrogensCytochrome P450 1A2enzyme
Conjugated estrogensCatechol O-methyltransferaseenzyme
Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
Conjugated estrogensMultidrug resistance-associated protein 4transporter
Conjugated estrogensMultidrug resistance-associated protein 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
Conjugated estrogensSodium/bile acid cotransportertransporter
Conjugated estrogensSolute carrier family 22 member 10transporter
Conjugated estrogensSolute carrier family 22 member 8transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
Conjugated estrogensP-glycoprotein 1transporter
Conjugated estrogensSolute carrier family 22 member 6transporter
Conjugated estrogensOrganic solute transporter subunit alphatransporter
Conjugated estrogensOrganic solute transporter subunit betatransporter
Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
Conjugated estrogensATP-binding cassette sub-family C member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
Conjugated estrogensSolute carrier family 22 member 11transporter
Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
Conjugated estrogensATP-binding cassette sub-family G member 2transporter
Conjugated estrogensThyroxine-binding globulincarrier
Conjugated estrogensSex hormone-binding globulincarrier
Conjugated estrogensSerum albumincarrier
Conjugated estrogensEstrogen receptor betatarget
RopivacaineSodium channel protein type 10 subunit alphatarget
RopivacaineCytochrome P450 1A2enzyme
RopivacaineCytochrome P450 2B6enzyme
RopivacaineCytochrome P450 3A4enzyme
Zolmitriptan5-hydroxytryptamine receptor 1Dtarget
Zolmitriptan5-hydroxytryptamine receptor 1Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Ftarget
ZolmitriptanCytochrome P450 1A2enzyme
ZolmitriptanAmine oxidase [flavin-containing] Aenzyme
Zolmitriptan5-hydroxytryptamine receptor 1Atarget
ZolmitriptanP-glycoprotein 1transporter
Zolmitriptan5-hydroxytryptamine receptor 7target
Zolmitriptan5-hydroxytryptamine receptor 2Atarget
Zolmitriptan5-hydroxytryptamine receptor 2Btarget
Zolmitriptan5-hydroxytryptamine receptor 1Etarget
AmitriptylineSodium-dependent serotonin transportertarget
AmitriptylineSodium-dependent noradrenaline transportertarget
AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
AmitriptylineAlpha-2A adrenergic receptortarget
AmitriptylineCytochrome P450 1A2enzyme
AmitriptylineCytochrome P450 2C19enzyme
AmitriptylineCytochrome P450 2D6enzyme
AmitriptylineSerum albumincarrier
AmitriptylineAlpha-1-acid glycoprotein 1carrier
AmitriptylineHistamine H1 receptortarget
Amitriptyline5-hydroxytryptamine receptor 2Atarget
Amitriptyline5-hydroxytryptamine receptor 1Atarget
AmitriptylineAlpha-1A adrenergic receptortarget
AmitriptylineCytochrome P450 3A4enzyme
AmitriptylineCytochrome P450 3A5enzyme
AmitriptylinePotassium voltage-gated channel subfamily A member 1target
AmitriptylineAlpha-1D adrenergic receptortarget
AmitriptylineDelta-type opioid receptortarget
AmitriptylineKappa-type opioid receptortarget
AmitriptylineHigh affinity nerve growth factor receptortarget
AmitriptylineBDNF/NT-3 growth factors receptortarget
AmitriptylineCytochrome P450 2C9enzyme
AmitriptylineCytochrome P450 2B6enzyme
AmitriptylineCytochrome P450 2C8enzyme
AmitriptylineHistamine H2 receptortarget
AmitriptylineHistamine H4 receptortarget
AmitriptylineSigma non-opioid intracellular receptor 1target
Amitriptyline5-hydroxytryptamine receptor 2Ctarget
AmitriptylineAlpha-1B adrenergic receptortarget
Amitriptyline5-hydroxytryptamine receptor 7target
Amitriptyline5-hydroxytryptamine receptor 1Dtarget
AmitriptylineMu-type opioid receptortarget
Amitriptyline5-hydroxytryptamine receptor 1Btarget
Amitriptyline5-hydroxytryptamine receptor 6target
AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
AmitriptylineUDP-glucuronosyltransferase 2B10enzyme
Amitriptyline5-hydroxytryptamine receptor 1Ctarget
AmitriptylineMuscarinic acetylcholine receptortarget
AmitriptylineHERG human cardiac K+ channeltarget
AmitriptylineP-glycoprotein 1transporter
AmitriptylineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineDopamine D1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M1target
OlanzapineMuscarinic acetylcholine receptor M3target
Olanzapine5-hydroxytryptamine receptor 2Atarget
OlanzapineDopamine D4 receptortarget
OlanzapineHistamine H1 receptortarget
OlanzapineMuscarinic acetylcholine receptor M4target
OlanzapineMuscarinic acetylcholine receptor M2target
OlanzapineDopamine D2 receptortarget
Olanzapine5-hydroxytryptamine receptor 2Ctarget
OlanzapineDopamine D3 receptortarget
OlanzapineAlpha-1B adrenergic receptortarget
OlanzapineCytochrome P450 1A2enzyme
Olanzapine5-hydroxytryptamine receptor 3Atarget
Olanzapine5-hydroxytryptamine receptor 6target
OlanzapineAlpha-1A adrenergic receptortarget
OlanzapineDopamine D5 receptortarget
OlanzapineSerum albumincarrier
OlanzapineAlpha-1-acid glycoprotein 1carrier
OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlanzapineCytochrome P450 2D6enzyme
OlanzapineP-glycoprotein 1transporter
OlanzapineCytochrome P450 2C19enzyme
OlanzapineD(1) dopamine receptortarget
OlanzapineBeta adrenergic receptortarget
Olanzapine5-hydroxytryptamine receptor 1target
OlanzapineGABA(A) Receptor Benzodiazepine Binding Sitetarget
OlanzapineCytochrome P450 2C9enzyme
OlanzapineUDP-glucuronosyltransferase 1-4enzyme
OlanzapineCytochrome P450 3A4enzyme
OlanzapineCytochrome P450 3A Subfamilyenzyme
ClozapineDopamine D4 receptortarget
ClozapineHistamine H1 receptortarget
ClozapineDopamine D2 receptortarget
ClozapineNeuron-specific vesicular protein calcyontarget
ClozapineHistamine H4 receptortarget
Clozapine5-hydroxytryptamine receptor 2Atarget
Clozapine5-hydroxytryptamine receptor 1Atarget
Clozapine5-hydroxytryptamine receptor 2Ctarget
ClozapineDopamine D1 receptortarget
ClozapineCytochrome P450 1A2enzyme
ClozapineCytochrome P450 2D6enzyme
ClozapineDopamine D3 receptortarget
ClozapineMuscarinic acetylcholine receptor M1target
ClozapineMuscarinic acetylcholine receptor M2target
ClozapineMuscarinic acetylcholine receptor M3target
ClozapineMuscarinic acetylcholine receptor M4target
ClozapineMuscarinic acetylcholine receptor M5target
Clozapine5-hydroxytryptamine receptor 1Btarget
Clozapine5-hydroxytryptamine receptor 1Dtarget
Clozapine5-hydroxytryptamine receptor 1Etarget
Clozapine5-hydroxytryptamine receptor 3Atarget
Clozapine5-hydroxytryptamine receptor 6target
Clozapine5-hydroxytryptamine receptor 7target
ClozapineAlpha-1A adrenergic receptortarget
ClozapineAlpha-1B adrenergic receptortarget
ClozapineAlpha-2A adrenergic receptortarget
ClozapineAlpha-2B adrenergic receptortarget
ClozapineAlpha-2C adrenergic receptortarget
ClozapineCytochrome P450 2C9enzyme
ClozapineP-glycoprotein 1transporter
ClozapineCytochrome P450 3A4enzyme
ClozapineCytochrome P450 2C19enzyme
ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
ClozapineUDP-glucuronosyltransferase 1-4enzyme
ClozapineCytochrome P450 1A1enzyme
ClozapineCytochrome P450 2A6enzyme
ClozapineCytochrome P450 2C8enzyme
ClozapineGlutathione S-transferase Ptarget
GrepafloxacinDNA gyrase subunit Atarget
GrepafloxacinDNA topoisomerase 4 subunit Atarget
GrepafloxacinCytochrome P450 3A4enzyme
GrepafloxacinCytochrome P450 1A2enzyme
GrepafloxacinSolute carrier family 22 member 2transporter
GrepafloxacinSolute carrier family 22 member 5transporter
GrepafloxacinCanalicular multispecific organic anion transporter 1transporter
GrepafloxacinP-glycoprotein 1transporter
GrepafloxacinMultidrug resistance-associated protein 1transporter
GrepafloxacinSolute carrier family 22 member 6transporter
Mirtazapine5-hydroxytryptamine receptor 2Atarget
Mirtazapine5HT3 serotonin receptortarget
MirtazapineAlpha-2A adrenergic receptortarget
Mirtazapine5-hydroxytryptamine receptor 2Ctarget
MirtazapineKappa-type opioid receptortarget
MirtazapineHistamine H1 receptortarget
MirtazapineCytochrome P450 1A2enzyme
MirtazapineCytochrome P450 3A4enzyme
MirtazapineCytochrome P450 2D6enzyme
MirtazapineAlpha-1 adrenergic receptorstarget
MirtazapineSodium-dependent serotonin transportertransporter
MexiletineSodium channel protein type 5 subunit alphatarget
MexiletineCytochrome P450 1A2enzyme
MexiletineCytochrome P450 2D6enzyme
MexiletineCytochrome P450 2B6enzyme
MexiletineCytochrome P450 2E1enzyme
MexiletineCytochrome P450 3A4enzyme
MexiletineAryl hydrocarbon receptortarget
TacrineAcetylcholinesterasetarget
TacrineCytochrome P450 1A2enzyme
TacrineCholinesterasetarget
TacrineP-glycoprotein 1transporter
TacrineLiver carboxylesterase 1target
ImipramineSodium-dependent noradrenaline transportertarget
ImipramineSodium-dependent serotonin transportertarget
ImipramineCytochrome P450 1A2enzyme
ImipramineCytochrome P450 2C19enzyme
ImipramineCytochrome P450 2D6enzyme
ImipramineHistamine H1 receptortarget
ImipramineAlpha-1A adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 2Atarget
ImipramineMuscarinic acetylcholine receptor M1target
ImipramineMuscarinic acetylcholine receptor M2target
ImipramineMuscarinic acetylcholine receptor M3target
ImipramineMuscarinic acetylcholine receptor M4target
ImipramineMuscarinic acetylcholine receptor M5target
ImipraminePotassium voltage-gated channel subfamily D member 2target
ImipraminePotassium voltage-gated channel subfamily D member 3target
ImipramineAlpha-1D adrenergic receptortarget
ImipramineAlpha-1-acid glycoprotein 1carrier
ImipramineSolute carrier family 22 member 2transporter
ImipramineSolute carrier family 22 member 3transporter
ImipramineP-glycoprotein 1transporter
ImipramineSolute carrier family 22 member 4transporter
ImipramineCytochrome P450 3A4enzyme
ImipramineCytochrome P450 2B6enzyme
ImipramineCytochrome P450 2C18enzyme
ImipramineCytochrome P450 2E1enzyme
ImipramineCytochrome P450 3A7enzyme
Imipramine5-hydroxytryptamine receptor 2Ctarget
ImipramineAlpha-1B adrenergic receptortarget
Imipramine5-hydroxytryptamine receptor 7target
ImipramineD(1) dopamine receptortarget
ImipramineDopamine D2 receptortarget
ImipraminePotassium voltage-gated channel subfamily H member 2target
ImipramineSodium-dependent dopamine transportertarget
Imipramine5-hydroxytryptamine receptor 1Atarget
Imipramine5-hydroxytryptamine receptor 6target
ImipraminePotassium voltage-gated channel subfamily H member 1target
ImipramineSerum albumincarrier
ImipramineAlpha-1-acid glycoprotein 2target
DuloxetineSodium-dependent serotonin transportertarget
DuloxetineSodium-dependent dopamine transportertarget
DuloxetineSodium-dependent noradrenaline transportertarget
DuloxetineCytochrome P450 1A2enzyme
DuloxetineCytochrome P450 2D6enzyme
DuloxetineCytochrome P450 2C9enzyme
DuloxetineSerum albumincarrier
Duloxetinealpha1-acid glycoproteincarrier
DuloxetineP-glycoprotein 1transporter
FlutamideAndrogen receptortarget
FlutamideCytochrome P450 1A2enzyme
FlutamideCytochrome P450 3A4enzyme
FlutamideCytochrome P450 1A1enzyme
FlutamideCytochrome P450 1B1enzyme
FlutamideCytochrome P450 2C19enzyme
FlutamideCytochrome P450 3A5enzyme
FlutamideAryl hydrocarbon receptortarget
FlutamideNuclear receptor subfamily 1 group I member 2target
HaloperidolDopamine D2 receptortarget
HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
HaloperidolDopamine D1 receptortarget
HaloperidolCytochrome P450 1A2enzyme
HaloperidolCytochrome P450 2D6enzyme
Haloperidol5-hydroxytryptamine receptor 2Atarget
HaloperidolDopamine D3 receptortarget
HaloperidolCytochrome P450 3A4enzyme
HaloperidolCytochrome P450 3A5enzyme
HaloperidolCytochrome P450 3A7enzyme
HaloperidolP-glycoprotein 1transporter
HaloperidolCarbonyl reductase [NADPH] 1enzyme
HaloperidolUDP-glucuronosyltransferase 1-9enzyme
HaloperidolCytochrome P450 2C19enzyme
HaloperidolCytochrome P450 2C9enzyme
HaloperidolMelanin-concentrating hormone receptor 1target
HaloperidolSynaptic vesicular amine transportertarget
Haloperidol5-hydroxytryptamine receptor 2Ctarget
HaloperidolSigma non-opioid intracellular receptor 1target
HaloperidolHistamine H1 receptortarget
HaloperidolMuscarinic acetylcholine receptor M3target
HaloperidolAlpha-1A adrenergic receptortarget
HaloperidolAlpha-2A adrenergic receptortarget
HaloperidolAlpha-2B adrenergic receptortarget
HaloperidolAlpha-2C adrenergic receptortarget
Haloperidol5-hydroxytryptamine receptor 1Atarget
Haloperidol5-hydroxytryptamine receptor 6target
Haloperidol5-hydroxytryptamine receptor 7target
HaloperidolCytochrome P450 1A1enzyme
NortriptylineSodium-dependent serotonin transportertarget
NortriptylineSodium-dependent noradrenaline transportertarget
NortriptylineCytochrome P450 1A2enzyme
NortriptylineCytochrome P450 2D6enzyme
NortriptylineSerum albumincarrier
NortriptylineAlpha-1-acid glycoprotein 1carrier
NortriptylineHistamine H1 receptortarget
Nortriptyline5-hydroxytryptamine receptor 2Atarget
NortriptylineAlpha-1A adrenergic receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Atarget
NortriptylineCytochrome P450 3A4enzyme
NortriptylineCytochrome P450 3A5enzyme
NortriptylineAlpha-1D adrenergic receptortarget
NortriptylineCytochrome P450 2C19enzyme
NortriptylineCytochrome P450 2E1enzyme
Nortriptyline5-hydroxytryptamine receptor 2Ctarget
NortriptylineAlpha-1B adrenergic receptortarget
NortriptylineAlpha-2 adrenergic receptorstarget
NortriptylineBeta adrenergic receptortarget
NortriptylineDopamine D2 receptortarget
NortriptylineSigma receptortarget
Nortriptyline5-hydroxytryptamine receptor 1Ctarget
NortriptylineSodium-dependent noradrenaline transportertransporter
NortriptylineMuscarinic acetylcholine receptortarget
NortriptylineP-glycoprotein 1transporter
FluorouracilThymidylate synthasetarget
FluorouracilCytochrome P450 1A2enzyme
FluorouracilThymidine phosphorylaseenzyme
FluorouracilSerum albumincarrier
FluorouracilCytochrome P450 2C9enzyme
FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
FluorouracilUridine phosphorylase 1enzyme
FluorouracilUridine phosphorylase 2enzyme
FluorouracilDNAtarget
FluorouracilRNAtarget
FluorouracilCytochrome P450 2A6enzyme
FluorouracilCytochrome P450 2C8enzyme
FluorouracilMethylenetetrahydrofolate reductaseenzyme
FluorouracilThymidylate synthaseenzyme
FluorouracilUridine 5'-monophosphate synthaseenzyme
FluorouracilAmidophosphoribosyltransferaseenzyme
FluorouracilSolute carrier family 22 member 7transporter
FluorouracilEquilibrative nucleoside transporter 1transporter
FluorouracilATP-binding cassette sub-family G member 2transporter
FluorouracilCanalicular multispecific organic anion transporter 2transporter
FluorouracilMultidrug resistance-associated protein 4transporter
FluorouracilMultidrug resistance-associated protein 5transporter
FluorouracilThyroxine-binding globulincarrier
PropranololBeta-1 adrenergic receptortarget
PropranololBeta-2 adrenergic receptortarget
PropranololBeta-3 adrenergic receptortarget
Propranolol5-hydroxytryptamine receptor 1Atarget
Propranolol5-hydroxytryptamine receptor 1Btarget
PropranololCytochrome P450 1A2enzyme
PropranololCytochrome P450 2D6enzyme
PropranololAlpha-1-acid glycoprotein 1carrier
PropranololCytochrome P450 2C19enzyme
PropranololCytochrome P450 3A4enzyme
PropranololCytochrome P450 3A5enzyme
PropranololCytochrome P450 3A7enzyme
PropranololSolute carrier family 22 member 2transporter
PropranololP-glycoprotein 1transporter
PropranololCytochrome P450 1A1enzyme
PropranololAmine oxidase [flavin-containing] Aenzyme
PropranololSerum albumincarrier
EstroneEstrogen receptor alphatarget
EstroneCytochrome P450 1A2enzyme
EstroneCytochrome P450 1A1enzyme
EstroneSerum albumincarrier
EstroneSolute carrier organic anion transporter family member 2B1transporter
EstroneP-glycoprotein 1transporter
EstroneSolute carrier organic anion transporter family member 1A2transporter
EstroneATP-binding cassette sub-family G member 2transporter
EstroneSolute carrier organic anion transporter family member 1B1transporter
EstroneCytochrome P450 3A4enzyme
EstroneCytochrome P450 1B1enzyme
EstroneCytochrome P450 2B6enzyme
EstroneCytochrome P450 2C9enzyme
EstroneCytochrome P450 2E1enzyme
EstroneCytochrome P450 3A5enzyme
EstroneEstrogen receptor betatarget
EstroneAndrogen receptortarget
EstroneCytochrome P450 19A1target
EstroneSex hormone-binding globulintarget
EstroneSolute carrier family 22 member 8transporter
VerapamilATP-sensitive inward rectifier potassium channel 11target
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
VerapamilPotassium voltage-gated channel subfamily H member 2target
VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
VerapamilCytochrome P450 1A2enzyme
VerapamilCytochrome P450 3A5enzyme
VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
VerapamilSodium-dependent serotonin transportertarget
VerapamilCytochrome P450 3A4enzyme
VerapamilP-glycoprotein 1transporter
VerapamilSolute carrier family 22 member 1transporter
VerapamilCanalicular multispecific organic anion transporter 2transporter
VerapamilMultidrug resistance-associated protein 4transporter
VerapamilSolute carrier family 22 member 5transporter
VerapamilSolute carrier organic anion transporter family member 1A2transporter
VerapamilMultidrug resistance-associated protein 7transporter
VerapamilSolute carrier family 22 member 4transporter
VerapamilSolute carrier organic anion transporter family member 1B1transporter
VerapamilCytochrome P450 2C8enzyme
VerapamilCytochrome P450 2C9enzyme
VerapamilCytochrome P450 2B6enzyme
VerapamilCytochrome P450 2C19enzyme
VerapamilCytochrome P450 2D6enzyme
VerapamilAlpha-1A adrenergic receptortarget
VerapamilAlpha-1B adrenergic receptortarget
VerapamilAlpha-1D adrenergic receptortarget
VerapamilSerum albumincarrier
VerapamilAlpha-1-acid glycoprotein 1carrier
VerapamilCytochrome P450 2C18enzyme
VerapamilCytochrome P450 2E1enzyme
VerapamilMultidrug resistance-associated protein 1transporter
VerapamilMultidrug and toxin extrusion protein 1transporter
VerapamilMultidrug and toxin extrusion protein 2transporter
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
WarfarinVitamin K epoxide reductase complex subunit 1target
WarfarinCytochrome P450 2C8enzyme
WarfarinCytochrome P450 1A2enzyme
WarfarinCytochrome P450 2C9enzyme
WarfarinAlpha-1-acid glycoprotein 1carrier
WarfarinSerum albumincarrier
WarfarinCytochrome P450 2C19enzyme
WarfarinCytochrome P450 3A4enzyme
WarfarinCytochrome P450 2C18enzyme
WarfarinNuclear receptor subfamily 1 group I member 2target
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
RiluzoleSodium channel protein type 5 subunit alphatarget
RiluzoleCytochrome P450 1A2enzyme
RiluzoleCystine/glutamate transportertarget
RiluzoleATP-binding cassette sub-family G member 2transporter
RiluzoleCytochrome P450 1A1enzyme
ZileutonArachidonate 5-lipoxygenasetarget
ZileutonCytochrome P450 2C9enzyme
ZileutonCytochrome P450 1A2enzyme
ZileutonCytochrome P450 3A4enzyme
ZileutonProstaglandin G/H synthase 1enzyme
ZileutonUDP-glucuronosyltransferase 1-9enzyme
ZileutonSerum albumincarrier
EstradiolEstrogen receptor alphatarget
EstradiolNuclear receptor subfamily 1 group I member 2target
EstradiolSex hormone-binding globulincarrier
EstradiolEstrogen receptor betatarget
EstradiolCytochrome P450 1A2enzyme
EstradiolUDP-glucuronosyltransferase 1-1enzyme
EstradiolSerum albumincarrier
EstradiolFatty acid-binding protein, intestinalcarrier
EstradiolCytochrome P450 3A4enzyme
EstradiolCytochrome P450 3A5enzyme
EstradiolCytochrome P450 3A7enzyme
EstradiolSolute carrier family 22 member 2transporter
EstradiolSolute carrier family 22 member 3transporter
EstradiolMultidrug resistance-associated protein 7transporter
EstradiolSolute carrier family 22 member 11transporter
EstradiolATP-binding cassette sub-family G member 2transporter
EstradiolSolute carrier organic anion transporter family member 1B1transporter
EstradiolP-glycoprotein 1transporter
EstradiolCytochrome P450 1A1enzyme
EstradiolCytochrome P450 1B1enzyme
EstradiolCytochrome P450 2C19enzyme
EstradiolCytochrome P450 2C8enzyme
EstradiolCytochrome P450 2C9enzyme
EstradiolSolute carrier family 22 member 8transporter
EstradiolSolute carrier organic anion transporter family member 1B3transporter
EstradiolSolute carrier organic anion transporter family member 1C1transporter
EstradiolNeuronal acetylcholine receptor subunit alpha-4target
EstradiolG-protein coupled estrogen receptor 1target
EstradiolATP synthase subunit atarget
EstradiolBeclin-1target
EstradiolUDP-glucuronosyltransferase 2B15enzyme
EstradiolCatechol O-methyltransferaseenzyme
EstradiolUDP-glucuronosyltransferases (UGTs)enzyme
DacarbazineDNA polymerase alpha subunit Btarget
DacarbazineCytochrome P450 1A1enzyme
DacarbazineCytochrome P450 1A2enzyme
DacarbazineCytochrome P450 2E1enzyme
Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DacarbazineDNAtarget
Ondansetron5-hydroxytryptamine receptor 3Atarget
OndansetronCytochrome P450 3A4enzyme
OndansetronCytochrome P450 1A2enzyme
OndansetronCytochrome P450 2D6enzyme
OndansetronCytochrome P450 3A5enzyme
OndansetronCytochrome P450 3A7enzyme
Ondansetron5-hydroxytryptamine receptor 4target
Ondansetron5-hydroxytryptamine receptor 1Atarget
Ondansetron5-hydroxytryptamine receptor 1Btarget
OndansetronMu-type opioid receptortarget
OndansetronCytochrome P450 2C9enzyme
OndansetronCytochrome P450 2E1enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
CyclobenzaprineCytochrome P450 1A2enzyme
CyclobenzaprineCytochrome P450 3A4enzyme
CyclobenzaprineCytochrome P450 2D6enzyme
CyclobenzaprineSerum albumincarrier
CyclobenzaprineUDP-glucuronosyltransferase 1-4enzyme
CyclobenzaprineUDP-glucuronosyltransferase 2B10enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Btarget
Cyclobenzaprine5-hydroxytryptamine receptor 2Ctarget
Cyclobenzaprine5-hydroxytryptamine receptor 7target
Cyclobenzaprine5-hydroxytryptamine receptor 6target
CyclobenzaprineSodium-dependent serotonin transportertarget
CyclobenzaprineSodium-dependent noradrenaline transportertarget
CyclobenzaprineToll-like receptor 4target
CyclobenzaprineAldehyde oxidasetarget
RamelteonMelatonin receptor type 1Btarget
RamelteonMelatonin receptor type 1Atarget
RamelteonCytochrome P450 1A2enzyme
RamelteonCytochrome P450 2C19enzyme
RamelteonCytochrome P450 3A4enzyme
RamelteonCytochrome P450 2C9enzyme
Frovatriptan5-hydroxytryptamine receptor 1Dtarget
Frovatriptan5-hydroxytryptamine receptor 1Btarget
FrovatriptanCytochrome P450 1A2enzyme
LevobupivacaineSodium channel protein type 10 subunit alphatarget
LevobupivacaineCytochrome P450 3A4enzyme
LevobupivacaineCytochrome P450 1A2enzyme
CinacalcetExtracellular calcium-sensing receptortarget
CinacalcetCytochrome P450 3A4enzyme
CinacalcetCytochrome P450 2D6enzyme
CinacalcetCytochrome P450 1A2enzyme
PimozideDopamine D2 receptortarget
PimozideCalmodulintarget
PimozidePotassium voltage-gated channel subfamily H member 2target
PimozideCytochrome P450 3A4enzyme
PimozideCytochrome P450 1A2enzyme
PimozideCytochrome P450 3A5enzyme
PimozideCytochrome P450 3A7enzyme
PimozideP-glycoprotein 1transporter
PimozideDopamine D3 receptortarget
PimozideCytochrome P450 2D6enzyme
PropafenoneSodium channel protein type 5 subunit alphatarget
PropafenonePotassium voltage-gated channel subfamily H member 2target
PropafenoneCytochrome P450 1A2enzyme
PropafenoneCytochrome P450 2D6enzyme
PropafenoneCytochrome P450 3A4enzyme
PropafenoneP-glycoprotein 1transporter
PropafenoneBeta-1 adrenergic receptortarget
PropafenoneBeta-2 adrenergic receptortarget
ClomipramineSodium-dependent serotonin transportertarget
ClomipramineSodium-dependent noradrenaline transportertarget
ClomipramineGlutathione S-transferase Ptarget
Clomipramine5-hydroxytryptamine receptor 2Atarget
ClomipramineCytochrome P450 1A2enzyme
ClomipramineCytochrome P450 2D6enzyme
ClomipramineCytochrome P450 2C19enzyme
ClomipramineP-glycoprotein 1transporter
ClomipramineCytochrome P450 3A4enzyme
Clomipramine5-hydroxytryptamine receptor 2Btarget
Clomipramine5-hydroxytryptamine receptor 2Ctarget
ClomipramineSerum albumincarrier
RasagilineApoptosis regulator Bcl-2target
RasagilineAmine oxidase [flavin-containing] Btarget
RasagilineCytochrome P450 1A2enzyme
ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
ChlorzoxazoneCytochrome P450 2E1enzyme
ChlorzoxazoneCytochrome P450 1A2enzyme
ChlorzoxazoneCytochrome P450 2A6enzyme
ChlorzoxazoneCytochrome P450 1A1enzyme
ChlorzoxazoneCytochrome P450 2D6enzyme
ChlorzoxazoneCytochrome P450 3A4enzyme
ChlorpromazineDopamine D2 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Atarget
ChlorpromazineCytochrome P450 2D6enzyme
ChlorpromazineCholinesteraseenzyme
ChlorpromazineCytochrome P450 1A2enzyme
ChlorpromazineSerum albumincarrier
ChlorpromazineP-glycoprotein 1transporter
ChlorpromazineDopamine D1 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 1Atarget
ChlorpromazineAlpha-1A adrenergic receptortarget
ChlorpromazineAlpha-1B adrenergic receptortarget
ChlorpromazineCytochrome P450 2E1enzyme
ChlorpromazineCytochrome P450 3A4enzyme
ChlorpromazineHistamine H1 receptortarget
ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
ChlorpromazineD(1) dopamine receptortarget
ChlorpromazineDopamine D3 receptortarget
ChlorpromazineDopamine D4 receptortarget
ChlorpromazineDopamine D5 receptortarget
Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
Chlorpromazine5-hydroxytryptamine 2 receptortarget
ChlorpromazineAlpha-1 adrenergic receptorstarget
ChlorpromazineAlpha-2 adrenergic receptorstarget
ChlorpromazineMuscarinic acetylcholine receptor M1target
ChlorpromazineMuscarinic acetylcholine receptor M3target
ChlorpromazineSphingomyelin phosphodiesterasetarget
ChlorpromazineCalmodulintarget
Chlorpromazinealpha1-acid glycoproteintarget
Chlorpromazine5-hydroxytryptamine receptor 6target
Chlorpromazine5-hydroxytryptamine receptor 7target
ChlorpromazineHistamine H4 receptortarget
ChlorpromazineBile salt export pumptransporter
MephenytoinSodium channel protein type 5 subunit alphatarget
MephenytoinCytochrome P450 2B6enzyme
MephenytoinCytochrome P450 2C9enzyme
MephenytoinCytochrome P450 2C19enzyme
MephenytoinCytochrome P450 1A2enzyme
MephenytoinCytochrome P450 2D6enzyme
MephenytoinCytochrome P450 2C8enzyme
MephenytoinNuclear receptor subfamily 1 group I member 2target
MephenytoinThyroxine-binding globulincarrier
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
AzelastineHistamine H1 receptortarget
AzelastineCytochrome P450 1A2enzyme
AzelastineCytochrome P450 2D6enzyme
AzelastineCytochrome P450 3A4enzyme
AzelastineCytochrome P450 2C19enzyme
AzelastineCytochrome P450 1A1enzyme
AzelastineCytochrome P450 3A5enzyme
AzelastineCytochrome P450 2C9enzyme
AzelastineCytochrome P450 2C8enzyme
AzelastineP-glycoprotein 1transporter
AzelastineCytochrome P450 2A6enzyme
AzelastineCytochrome P450 2E1enzyme
AzelastineHistamine H2 receptortarget
AzelastinePhospholipase A2target
AzelastineLeukotriene C4 synthasetarget
AzelastineCytochrome P450 2B6enzyme
AcenocoumarolVitamin K epoxide reductase complex subunit 1target
AcenocoumarolCytochrome P450 2C9enzyme
AcenocoumarolCytochrome P450 1A2enzyme
AcenocoumarolSerum albumincarrier
AcenocoumarolAlpha-1-acid glycoprotein 1carrier
AcenocoumarolCytochrome P450 2C19enzyme
AcenocoumarolCytochrome P450 3A4enzyme
AcenocoumarolP-glycoprotein 1transporter
AminophenazoneCytochrome P450 2C19enzyme
AminophenazoneCytochrome P450 1A2enzyme
AminophenazoneCytochrome P450 2C8enzyme
AminophenazoneSolute carrier family 22 member 6transporter
AminophenazoneCytochrome P450 2C9enzyme
AminophenazoneCytochrome P450 2D6enzyme
AminophenazoneCytochrome P450 3A4enzyme
AminophenazoneCytochrome P450 2C18enzyme
AminophenazoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Palonosetron5-hydroxytryptamine receptor 3Atarget
PalonosetronCytochrome P450 2D6enzyme
PalonosetronCytochrome P450 3A4enzyme
PalonosetronCytochrome P450 1A2enzyme
MelatoninAcetylserotonin O-methyltransferasetarget
MelatoninMelatonin receptor type 1Atarget
MelatoninMelatonin receptor type 1Btarget
MelatoninNuclear receptor ROR-betatarget
MelatoninCalmodulintarget
MelatoninCalreticulintarget
MelatoninRibosyldihydronicotinamide dehydrogenase [quinone]target
MelatoninMyeloperoxidasetarget
MelatoninEstrogen receptor alphatarget
MelatoninEosinophil peroxidasetarget
MelatoninCytochrome P450 1A1enzyme
MelatoninCytochrome P450 1A2enzyme
MelatoninCytochrome P450 2C19enzyme
MelatoninCytochrome P450 2C9enzyme
MelatoninAcetylserotonin O-methyltransferaseenzyme
MelatoninIndoleamine 2,3-dioxygenase 1enzyme
MelatoninMyeloperoxidaseenzyme
MelatoninCytochrome P450 1B1enzyme
MelatoninSolute carrier family 22 member 8transporter
MelatoninCytochrome P450 19A1enzyme
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
DoxepinSodium-dependent serotonin transportertarget
DoxepinSodium-dependent noradrenaline transportertarget
DoxepinHistamine H1 receptortarget
DoxepinHistamine H2 receptortarget
DoxepinCytochrome P450 2D6enzyme
DoxepinMuscarinic acetylcholine receptor M1target
DoxepinMuscarinic acetylcholine receptor M2target
DoxepinMuscarinic acetylcholine receptor M3target
DoxepinMuscarinic acetylcholine receptor M4target
DoxepinMuscarinic acetylcholine receptor M5target
DoxepinAlpha-1A adrenergic receptortarget
Doxepin5-hydroxytryptamine receptor 1Atarget
Doxepin5-hydroxytryptamine receptor 2Atarget
DoxepinCytochrome P450 2C19enzyme
DoxepinCytochrome P450 2C9enzyme
DoxepinCytochrome P450 1A2enzyme
DoxepinP-glycoprotein 1transporter
Doxepin5-hydroxytryptamine receptor 2Btarget
Doxepin5-hydroxytryptamine receptor 2Ctarget
DoxepinAlpha-1B adrenergic receptortarget
DoxepinAlpha-1D adrenergic receptortarget
DoxepinCytochrome P450 3A4enzyme
Doxepin5-hydroxytryptamine receptor 6target
DoxepinHistamine H4 receptortarget
DoxepinPotassium voltage-gated channel subfamily H member 2target
DoxepinSerum albumincarrier
DoxepinAlpha-1-acid glycoprotein 1carrier
CarbamazepineVoltage-gated sodium channel alpha subunittarget
CarbamazepineCytochrome P450 2C8enzyme
CarbamazepineCytochrome P450 2B6enzyme
CarbamazepineCytochrome P450 3A4enzyme
CarbamazepineCytochrome P450 1A2enzyme
CarbamazepineCytochrome P450 2C19enzyme
CarbamazepineCytochrome P450 2C9enzyme
CarbamazepineP-glycoprotein 1transporter
CarbamazepineCytochrome P450 3A5enzyme
CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
CarbamazepineRalA-binding protein 1transporter
CarbamazepineCanalicular multispecific organic anion transporter 1transporter
CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
CarbamazepineNuclear receptor subfamily 1 group I member 2target
CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-1target
ZolpidemCytochrome P450 3A4enzyme
ZolpidemCytochrome P450 1A2enzyme
ZolpidemGamma-aminobutyric acid receptor subunit alpha-2target
ZolpidemGamma-aminobutyric acid receptor subunit alpha-3target
ZolpidemCytochrome P450 2C9enzyme
ZolpidemCytochrome P450 2C19enzyme
ZolpidemCytochrome P450 2D6enzyme
ZolpidemGamma-aminobutyric acid receptor subunit gamma-2target
FluoxetineSodium-dependent serotonin transportertarget
FluoxetineCytochrome P450 2C9enzyme
FluoxetineCytochrome P450 2D6enzyme
FluoxetineCYP2B proteinenzyme
FluoxetineCytochrome P450 1A2enzyme
FluoxetineCytochrome P450 3A4enzyme
FluoxetineCytochrome P450 2C19enzyme
FluoxetineP-glycoprotein 1transporter
FluoxetineCytochrome P450 2B6enzyme
FluoxetineCytochrome P450 3A5enzyme
FluoxetineSerum albumincarrier
FluoxetineAlpha-1-acid glycoprotein 1carrier
FluoxetinePotassium voltage-gated channel subfamily H member 2target
Fluoxetine5-hydroxytryptamine receptor 2Ctarget
FluoxetineCyclin-dependent kinases regulatory subunit 1target
FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
FluoxetineNeuronal acetylcholine receptor subunit beta-4target
AntipyrineCytochrome P450 2C8enzyme
AntipyrineCytochrome P450 2C9enzyme
AntipyrineCytochrome P450 1A2enzyme
AntipyrineCytochrome P450 2C19enzyme
AntipyrineCytochrome P450 3A4enzyme
AntipyrineSolute carrier family 22 member 6transporter
AntipyrineCytochrome P450 2A6enzyme
AntipyrineCytochrome P450 2B6enzyme
AntipyrineCytochrome P450 2C18enzyme
AntipyrineCytochrome P450 2D6enzyme
AntipyrineCytochrome P450 2E1enzyme
AntipyrineProstaglandin G/H synthase 2target
AntipyrineProstaglandin G/H synthase 1target
TerbinafineSqualene monooxygenasetarget
TerbinafineCytochrome P450 2D6enzyme
TerbinafineCytochrome P450 2C9enzyme
TerbinafineCytochrome P450 1A2enzyme
TerbinafineCytochrome P450 3A4enzyme
TerbinafineCytochrome P450 2C8enzyme
TerbinafineCytochrome P450 2C19enzyme
TerbinafineProstaglandin G/H synthase 1enzyme
TerbinafineSerum albumincarrier
Terbinafinealpha1-acid glycoproteincarrier
TerbinafineABC multidrug transporter MDR2transporter
TerbinafineSqualene monooxygenasetarget
CinnarizineHistamine H1 receptortarget
CinnarizineDopamine D2 receptortarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
CinnarizineCytochrome P450 2D6enzyme
CinnarizineCytochrome P450 2B6enzyme
CinnarizineCytochrome P450 2C9enzyme
CinnarizineCytochrome P450 1A1enzyme
CinnarizineCytochrome P450 1A2enzyme
CinnarizineCytochrome P450 2A6enzyme
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Starget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
CinnarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
CinnarizineD(1) dopamine receptortarget
CinnarizineMuscarinic acetylcholine receptortarget
CinnarizineCytochrome P450 3A4enzyme
FlunarizineHistamine H1 receptortarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
FlunarizineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
FlunarizineCalmodulintarget
FlunarizineCytochrome P450 2D6enzyme
FlunarizineCytochrome P450 2C9enzyme
FlunarizineCytochrome P450 1A1enzyme
FlunarizineCytochrome P450 1A2enzyme
FlunarizineCytochrome P450 2A6enzyme
FlunarizineCytochrome P450 3A4enzyme
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
AminophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
AminophyllineAdenosine receptor A3target
AminophyllineAdenosine receptor A1target
AminophyllineCytochrome P450 1A2enzyme
AminophyllineCytochrome P450 2E1enzyme
AminophyllineCytochrome P450 3A4enzyme
AminophyllineHistone deacetylase 2target
Asenapine5-hydroxytryptamine receptor 1Atarget
Asenapine5-hydroxytryptamine receptor 1Btarget
Asenapine5-hydroxytryptamine receptor 2Atarget
Asenapine5-hydroxytryptamine receptor 2Btarget
Asenapine5-hydroxytryptamine receptor 2Ctarget
Asenapine5-hydroxytryptamine receptor 6target
Asenapine5-hydroxytryptamine receptor 7target
AsenapineAlpha-2A adrenergic receptortarget
AsenapineAlpha-2B adrenergic receptortarget
AsenapineAlpha-2C adrenergic receptortarget
AsenapineAlpha-1A adrenergic receptortarget
AsenapineDopamine D1 receptortarget
AsenapineDopamine D2 receptortarget
AsenapineDopamine D3 receptortarget
AsenapineDopamine D4 receptortarget
AsenapineHistamine H1 receptortarget
AsenapineHistamine H2 receptortarget
AsenapineCytochrome P450 1A2enzyme
AsenapineCytochrome P450 2D6enzyme
Asenapine5-hydroxytryptamine receptor 5Atarget
AsenapineUDP-glucuronosyltransferase 1-4enzyme
AsenapineCytochrome P450 3A4enzyme
AsenapineBeta-1 adrenergic receptortarget
AsenapineBeta-2 adrenergic receptortarget
AsenapineSerum albumincarrier
Asenapinealpha1-acid glycoproteincarrier
BetaxololBeta-1 adrenergic receptortarget
BetaxololBeta-2 adrenergic receptortarget
BetaxololCytochrome P450 1A2enzyme
BetaxololCytochrome P450 2D6enzyme
Estrone sulfateCytochrome P450 1A2enzyme
Estrone sulfateCytochrome P450 3A4enzyme
Estrone sulfateEstrogen receptor alphatarget
Estrone sulfateEstrogen receptor betatarget
Estrone sulfateSex hormone-binding globulincarrier
Estrone sulfateSerum albumincarrier
Estrone sulfateCytochrome P450 2C9enzyme
Estrone sulfateMultidrug and toxin extrusion protein 1transporter
Estrone sulfateMultidrug and toxin extrusion protein 2transporter
GuanabenzAlpha-2A adrenergic receptortarget
GuanabenzCytochrome P450 1A2enzyme
GuanabenzAlpha-2B adrenergic receptortarget
ThiothixeneCytochrome P450 1A2enzyme
ThiothixeneCytochrome P450 2D6enzyme
ThiothixeneDopamine D2 receptortarget
ThiothixeneDopamine D1 receptortarget
Thiothixene5-hydroxytryptamine receptor 2Atarget
ThiothixeneSolute carrier family 22 member 1transporter
ThiothixeneSerum albumincarrier
TrifluoperazineDopamine D2 receptortarget
TrifluoperazineAlpha-1A adrenergic receptortarget
TrifluoperazineNeuron-specific vesicular protein calcyontarget
TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
TrifluoperazineCytochrome P450 1A2enzyme
TrifluoperazineP-glycoprotein 1transporter
TrifluoperazineCalmodulintarget
TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
TrifluoperazineProtein S100-A4target
PromazineDopamine D2 receptortarget
Promazine5-hydroxytryptamine receptor 2Atarget
Promazine5-hydroxytryptamine receptor 2Ctarget
PromazineAlpha-1A adrenergic receptortarget
PromazineMuscarinic acetylcholine receptor M1target
PromazineHistamine H1 receptortarget
PromazineCytochrome P450 2C19enzyme
PromazineCytochrome P450 1A2enzyme
PromazineCytochrome P450 3A4enzyme
PromazineCytochrome P450 2C9enzyme
PromazineCytochrome P450 2D6enzyme
CarvedilolAlpha-1A adrenergic receptortarget
CarvedilolBeta-1 adrenergic receptortarget
CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
CarvedilolBeta-2 adrenergic receptortarget
CarvedilolVascular endothelial growth factor Atarget
CarvedilolNatriuretic peptides Btarget
CarvedilolGap junction alpha-1 proteintarget
CarvedilolPotassium voltage-gated channel subfamily H member 2target
CarvedilolVascular cell adhesion protein 1target
CarvedilolCytochrome P450 2C9enzyme
CarvedilolCytochrome P450 2D6enzyme
CarvedilolXanthine dehydrogenase/oxidaseenzyme
CarvedilolP-glycoprotein 1transporter
CarvedilolCytochrome P450 1A2enzyme
CarvedilolCytochrome P450 3A4enzyme
CarvedilolCytochrome P450 1A1enzyme
CarvedilolCytochrome P450 2E1enzyme
CarvedilolAlpha-1D adrenergic receptortarget
CarvedilolAlpha-1B adrenergic receptortarget
CarvedilolAlpha-2C adrenergic receptortarget
CarvedilolAlpha-2B adrenergic receptortarget
CarvedilolAlpha-2A adrenergic receptortarget
CarvedilolE-selectintarget
CarvedilolHypoxia-inducible factor 1-alphatarget
CarvedilolInward rectifier potassium channel 4target
CarvedilolUDP-glucuronosyltransferase 1-1enzyme
CarvedilolSerum albumincarrier
CarvedilolUDP-glucuronosyltransferase 2B4enzyme
CarvedilolUDP-glucuronosyltransferase 2B7enzyme
CarvedilolInward rectifier potassium channel 2target
CarvedilolAlpha-1 adrenergic receptorstarget
GenisteinEstrogen receptor betatarget
GenisteinDNA topoisomerase 2-alphatarget
GenisteinProtein-tyrosine kinase 2-betatarget
GenisteinP-glycoprotein 1transporter
GenisteinMultidrug resistance-associated protein 1transporter
GenisteinATP-binding cassette sub-family G member 2transporter
GenisteinCytochrome P450 1A2enzyme
GenisteinNuclear receptor coactivator 1target
GenisteinEstrogen receptor alphatarget
GenisteinNuclear receptor coactivator 2target
GenisteinTransthyretincarrier
GenisteinSteroid hormone receptor ERR2target
GenisteinSteroid hormone receptor ERR1target
GenisteinNuclear receptor subfamily 1 group I member 2target
GenisteinRAC-alpha serine/threonine-protein kinasetarget
GenisteinG-protein coupled estrogen receptor 1target
GenisteinCytochrome P450 1B1target
GenisteinSex hormone-binding globulintarget
GenisteinCytochrome P450 1A1enzyme
GenisteinSolute carrier organic anion transporter family member 1B1transporter
GenisteinSolute carrier organic anion transporter family member 2B1transporter
GenisteinCytochrome P450 2C8enzyme
GenisteinCytochrome P450 2C9enzyme
GenisteinCytochrome P450 3A1enzyme
GenisteinCytochrome P450 3A2enzyme
GenisteinCytochrome P450 3A4enzyme
ResveratrolTransthyretincarrier
ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
ResveratrolProstaglandin G/H synthase 1target
ResveratrolCasein kinase II subunit alphatarget
ResveratrolProstaglandin G/H synthase 2target
ResveratrolNAD-dependent protein deacetylase sirtuin-1target
ResveratrolCytochrome P450 1A1enzyme
ResveratrolCytochrome P450 3A4enzyme
ResveratrolCytochrome P450 1A2enzyme
ResveratrolCytochrome P450 1B1enzyme
ResveratrolArachidonate 15-lipoxygenasetarget
ResveratrolArachidonate 5-lipoxygenasetarget
ResveratrolAryl hydrocarbon receptortarget
ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
ResveratrolIntegrin alpha-5target
ResveratrolIntegrin beta-3target
ResveratrolSerum albumincarrier
ResveratrolAmyloid beta A4 proteintarget
ResveratrolAlpha-synucleintarget
ResveratrolEstrogen receptor alphatarget
ResveratrolMelatonin receptor type 1Atarget
ResveratrolMelatonin receptor type 1Btarget
ResveratrolC-type lectin domain family 14 member Atarget
ResveratrolNuclear receptor subfamily 1 group I member 2target
ResveratrolNuclear receptor subfamily 1 group I member 3target
ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
ResveratrolCarbonyl reductase [NADPH] 1target
ResveratrolPeroxisome proliferator-activated receptor alphatarget
ResveratrolPeroxisome proliferator-activated receptor gammatarget
ResveratrolRAC-alpha serine/threonine-protein kinasetarget
ResveratrolFar upstream element-binding protein 2target
ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
AlbendazoleTubulin alpha-1A chaintarget
AlbendazoleTubulin beta-4B chaintarget
AlbendazoleCytochrome P450 3A4enzyme
AlbendazoleFumarate reductase flavoprotein subunittarget
AlbendazoleCytochrome P450 1A1enzyme
AlbendazoleCytochrome P450 1A2enzyme
AlbendazoleTubulin beta-2 chaintarget
AlbendazoleCytochrome P450 2C19enzyme
AlbendazoleP-glycoprotein 1transporter
BromazepamCytochrome P450 1A2enzyme
BromazepamCytochrome P450 2C19enzyme
BromazepamCytochrome P450 2E1enzyme
BromazepamGABA(A) Receptortarget
BromazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DesipramineMuscarinic acetylcholine receptor M1target
DesipramineSodium-dependent noradrenaline transportertarget
DesipramineBeta-2 adrenergic receptortarget
DesipramineMuscarinic acetylcholine receptor M2target
DesipramineSodium-dependent serotonin transportertarget
DesipramineHistamine H1 receptortarget
DesipramineBeta-1 adrenergic receptortarget
DesipramineCytochrome P450 2D6enzyme
DesipramineMuscarinic acetylcholine receptor M3target
DesipramineMuscarinic acetylcholine receptor M4target
DesipramineMuscarinic acetylcholine receptor M5target
DesipramineAlpha-1 adrenergic receptorstarget
Desipramine5-hydroxytryptamine receptor 2Atarget
DesipramineAlpha-1-acid glycoprotein 1carrier
DesipramineCytochrome P450 2B6enzyme
DesipramineCytochrome P450 3A4enzyme
DesipramineSolute carrier family 22 member 2transporter
DesipramineSolute carrier family 22 member 1transporter
DesipramineSolute carrier family 22 member 3transporter
DesipramineSolute carrier family 22 member 5transporter
DesipramineP-glycoprotein 1transporter
DesipramineSolute carrier family 22 member 4transporter
DesipramineCytochrome P450 1A2enzyme
DesipramineCytochrome P450 2E1enzyme
DesipramineSphingomyelin phosphodiesterasetarget
Desipramine5-hydroxytryptamine receptor 1Atarget
Desipramine5-hydroxytryptamine receptor 2Ctarget
DesipramineDopamine D2 receptortarget
DesipramineAlpha-2 adrenergic receptorstarget
DexfenfluramineSodium-dependent serotonin transportertarget
Dexfenfluramine5-hydroxytryptamine receptor 2Ctarget
DexfenfluramineCytochrome P450 2D6enzyme
DexfenfluramineCytochrome P450 1A2enzyme
DexfenfluramineCytochrome P450 2E1enzyme
DomperidoneDopamine D2 receptortarget
DomperidoneCytochrome P450 3A4enzyme
DomperidoneCytochrome P450 3A5enzyme
DomperidoneCytochrome P450 3A7enzyme
DomperidoneP-glycoprotein 1transporter
DomperidoneCytochrome P450 1A2enzyme
DomperidoneCytochrome P450 2B6enzyme
DomperidoneCytochrome P450 2C8enzyme
DomperidoneCytochrome P450 2D6enzyme
DomperidoneDopamine D3 receptortarget
EthanolGamma-aminobutyric acid receptor subunit alpha-1target
EthanolGlutamate receptor ionotropic, NMDA 3Atarget
EthanolGlycine receptor subunit alpha-1target
EthanolGlycine receptor subunit alpha-2target
EthanolCytochrome P450 2E1enzyme
EthanolCytochrome P450 1A1enzyme
EthanolCytochrome P450 1A2enzyme
EthanolCytochrome P450 2B6enzyme
EthanolCytochrome P450 2C19enzyme
EthanolCytochrome P450 2C9enzyme
EthanolCytochrome P450 3A4enzyme
EthanolCytochrome P450 4A11enzyme
EthanolAlcohol dehydrogenase 1Aenzyme
EthanolAlcohol dehydrogenase 1Benzyme
EthanolAlcohol dehydrogenase 1Cenzyme
EthanolAlcohol dehydrogenase class-3enzyme
EthanolVoltage-dependent L-type calcium channel subunit beta-1target
Ethanol5-hydroxytryptamine receptor 3Atarget
EthanolAlcohol dehydrogenase 4enzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-2target
EthanolNeuronal acetylcholine receptor subunit alpha-10target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EthanolGamma-aminobutyric acid receptor subunit alpha-5target
EthanolGamma-aminobutyric acid receptor subunit alpha-4target
EthanolAlcohol dehydrogenase class 4 mu/sigma chainenzyme
EthanolGamma-aminobutyric acid receptor subunit alpha-3target
EthanolGlutamate receptor 1target
EthanolVoltage-dependent calcium channel gamma-1 subunittarget
EthanolNeuronal acetylcholine receptor subunit alpha-2target
EthanolGamma-aminobutyric acid receptor subunit alpha-6target
EthanolGlutamate receptor 2target
EthanolGlutamate receptor 4target
EthanolGlutamate receptor 3target
EthanolNeuronal acetylcholine receptor subunit alpha-4target
EthanolNeuronal acetylcholine receptor subunit beta-2target
EthanolG protein-activated inward rectifier potassium channel 1target
EthanolG protein-activated inward rectifier potassium channel 2target
EthanolVascular cell adhesion protein 1target
EthanolEquilibrative nucleoside transporter 1target
EthanolG protein-activated inward rectifier potassium channel 4target
EthanolNeuronal acetylcholine receptor subunit alpha-7target
EthanolNeuronal acetylcholine receptor subunit alpha-9target
EthanolGamma-aminobutyric acid receptor subunit beta-1target
EthanolGamma-aminobutyric acid receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit beta-2target
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Starget
EthanolVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
EthanolAlcohol dehydrogenase 6enzyme
EthanolNeuronal acetylcholine receptor subunit beta-4target
EthanolNeuronal acetylcholine receptor subunit alpha-3target
EthanolNeuronal acetylcholine receptor subunit alpha-5target
EthanolNeuronal acetylcholine receptor subunit alpha-6target
EthanolNeuronal acetylcholine receptor subunit beta-3target
EthanolGamma-aminobutyric acid receptor subunit gamma-1target
EthanolGamma-aminobutyric acid receptor subunit gamma-3target
EthanolGamma-aminobutyric acid receptor subunit epsilontarget
EthanolGamma-aminobutyric acid receptor subunit pitarget
EthanolGamma-aminobutyric acid receptor subunit thetatarget
EthanolGamma-aminobutyric acid receptor subunit deltatarget
EthanolAlcohol dehydrogenase [NADP(+)]enzyme
EthanolEquilibrative nucleoside transporter 2target
Ethanol5-hydroxytryptamine receptor 3Etarget
Ethanol5-hydroxytryptamine receptor 3Btarget
Ethanol5-hydroxytryptamine receptor 3Dtarget
Ethanol5-hydroxytryptamine receptor 3Ctarget
EthanolVoltage-dependent calcium channel gamma-2 subunittarget
EthanolG protein-activated inward rectifier potassium channel 3target
EthanolNeural cell adhesion molecule L1target
EtoposideDNA topoisomerase 2-alphatarget
EtoposideCytochrome P450 3A4enzyme
EtoposideCanalicular multispecific organic anion transporter 2transporter
EtoposideMultidrug resistance-associated protein 6transporter
EtoposideP-glycoprotein 1transporter
EtoposideMultidrug resistance-associated protein 1transporter
EtoposideMultidrug resistance-associated protein 7transporter
EtoposideCanalicular multispecific organic anion transporter 1transporter
EtoposideATP-binding cassette sub-family G member 2transporter
EtoposideCytochrome P450 1A2enzyme
EtoposideCytochrome P450 2E1enzyme
EtoposideCytochrome P450 3A5enzyme
EtoposideUDP-glucuronosyltransferase 1-1enzyme
EtoposideDNA topoisomerase 2-betatarget
EtoposideGlutathione S-transferase theta-1enzyme
EtoposideGlutathione S-transferase Penzyme
EtoposideProstaglandin G/H synthase 2enzyme
EtoposideProstaglandin G/H synthase 1enzyme
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
MaprotilineHistamine H1 receptortarget
MaprotilineSodium-dependent noradrenaline transportertarget
MaprotilineAlpha-1 adrenergic receptorstarget
MaprotilineCytochrome P450 2D6enzyme
MaprotilineAlpha-1-acid glycoprotein 1carrier
MaprotilineMuscarinic acetylcholine receptor M1target
MaprotilineMuscarinic acetylcholine receptor M2target
MaprotilineMuscarinic acetylcholine receptor M3target
MaprotilineMuscarinic acetylcholine receptor M4target
MaprotilineMuscarinic acetylcholine receptor M5target
MaprotilineCytochrome P450 1A2enzyme
Maprotiline5-hydroxytryptamine receptor 2Atarget
Maprotiline5-hydroxytryptamine receptor 2Ctarget
Maprotiline5-hydroxytryptamine receptor 7target
MaprotilineDopamine D2 receptortarget
MaprotilineAlpha-2 adrenergic receptorstarget
MethadoneNMDA receptortarget
MethadoneMu-type opioid receptortarget
MethadoneCytochrome P450 2B6enzyme
MethadoneCytochrome P450 3A4enzyme
MethadoneCytochrome P450 2C19enzyme
MethadoneDelta-type opioid receptortarget
MethadoneCytochrome P450 3A7enzyme
MethadoneCytochrome P450 2D6enzyme
MethadoneP-glycoprotein 1transporter
MethadoneCytochrome P450 2C8enzyme
MethadoneCytochrome P450 19A1enzyme
MethadoneCytochrome P450 1A2enzyme
MethadoneCytochrome P450 2C18enzyme
MethadoneCytochrome P450 2C9enzyme
Methadone5-hydroxytryptamine receptor 3Atarget
MethadoneAlpha-1-acid glycoprotein 1carrier
MethadoneSerum albumincarrier
MethadoneNeuronal acetylcholine receptor subunit alpha-7target
MethadoneNeuronal acetylcholine receptor subunit alpha-3target
MethadoneNeuronal acetylcholine receptor subunit alpha-4target
MethadoneNeuronal acetylcholine receptor subunit beta-2target
MethoxyfluraneCalcium-transporting ATPase type 2C member 1target
MethoxyfluraneNADH-ubiquinone oxidoreductase chain 1target
MethoxyfluraneGamma-aminobutyric acid receptor subunit alpha-1target
MethoxyfluranePotassium voltage-gated channel subfamily A member 1target
MethoxyfluraneGlutamate receptor 1target
MethoxyfluraneGlycine receptor subunit alpha-1target
MethoxyfluraneCytochrome P450 2E1enzyme
MethoxyfluraneCytochrome P450 1A2enzyme
MethoxyfluraneCytochrome P450 2A6enzyme
MethoxyfluraneCytochrome P450 2B6enzyme
MethoxyfluraneCytochrome P450 2C9enzyme
MethoxyfluraneCytochrome P450 2D6enzyme
MethoxyfluraneCytochrome P450 3A4enzyme
MethoxyfluraneGABA(A) Receptortarget
MianserinHistamine H1 receptortarget
MianserinAlpha-2A adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Atarget
Mianserin5-hydroxytryptamine receptor 2Ctarget
MianserinCytochrome P450 2D6enzyme
MianserinSodium-dependent serotonin transportertarget
MianserinCytochrome P450 3A4enzyme
MianserinCytochrome P450 1A2enzyme
MianserinCytochrome P450 2B6enzyme
MianserinSodium-dependent noradrenaline transportertarget
MianserinHistamine H4 receptortarget
Mianserin5-hydroxytryptamine receptor 1Atarget
MianserinAlpha-2C adrenergic receptortarget
Mianserin5-hydroxytryptamine receptor 2Btarget
Mianserin5-hydroxytryptamine receptor 1Ftarget
MianserinAlpha-2B adrenergic receptortarget
MianserinDopamine D3 receptortarget
MianserinKappa-type opioid receptortarget
MianserinSodium-dependent dopamine transportertarget
Mianserin5-hydroxytryptamine receptor 7target
MianserinDopamine D2 receptortarget
Mianserin5-hydroxytryptamine receptor 6target
MianserinAlpha-1 adrenergic receptorstarget
MianserinD(1) dopamine receptortarget
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
PerphenazineDopamine D1 receptortarget
PerphenazineDopamine D2 receptortarget
PerphenazineCalmodulintarget
PerphenazineCytochrome P450 2D6enzyme
PerphenazineCytochrome P450 1A2enzyme
PerphenazineCytochrome P450 2C18enzyme
PerphenazineCytochrome P450 2C19enzyme
PerphenazineCytochrome P450 2C8enzyme
PerphenazineCytochrome P450 2C9enzyme
PerphenazineCytochrome P450 3A4enzyme
SelegilineAmine oxidase [flavin-containing] Btarget
SelegilineCytochrome P450 2B6enzyme
SelegilineAmine oxidase [flavin-containing] Atarget
SelegilineCytochrome P450 2A6enzyme
SelegilineCytochrome P450 3A4enzyme
SelegilineP-glycoprotein 1transporter
SelegilineCytochrome P450 1A2enzyme
SelegilineCytochrome P450 2C19enzyme
SelegilineCytochrome P450 2C8enzyme
SelegilineCytochrome P450 2C9enzyme
SelegilineCytochrome P450 2D6enzyme
SelegilineCytochrome P450 2E1enzyme
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TolperisoneCytochrome P450 1A2enzyme
ZiprasidoneAlpha-1A adrenergic receptortarget
ZiprasidoneDopamine D2 receptortarget
Ziprasidone5-hydroxytryptamine receptor 2Ctarget
ZiprasidoneDopamine D3 receptortarget
Ziprasidone5-hydroxytryptamine receptor 1Atarget
Ziprasidone5-hydroxytryptamine receptor 1Dtarget
ZiprasidoneHistamine H1 receptortarget
Ziprasidone5-hydroxytryptamine receptor 2Atarget
ZiprasidoneDopamine D4 receptortarget
Ziprasidone5-hydroxytryptamine receptor 7target
ZiprasidoneCytochrome P450 3A4enzyme
ZiprasidoneAlpha-2A adrenergic receptortarget
ZiprasidoneAlpha-1B adrenergic receptortarget
ZiprasidoneAlpha-2B adrenergic receptortarget
ZiprasidoneAlpha-2C adrenergic receptortarget
ZiprasidoneDopamine D1 receptortarget
ZiprasidoneDopamine D5 receptortarget
ZiprasidoneMuscarinic acetylcholine receptor M1target
ZiprasidoneMuscarinic acetylcholine receptor M2target
ZiprasidoneMuscarinic acetylcholine receptor M3target
ZiprasidoneMuscarinic acetylcholine receptor M4target
ZiprasidoneMuscarinic acetylcholine receptor M5target
Ziprasidone5-hydroxytryptamine receptor 1Btarget
Ziprasidone5-hydroxytryptamine receptor 1Etarget
Ziprasidone5-hydroxytryptamine receptor 6target
ZiprasidoneAldehyde oxidaseenzyme
ZiprasidoneSerum albumincarrier
ZiprasidoneP-glycoprotein 1transporter
ZiprasidoneAlpha-1-acid glycoprotein 1carrier
Ziprasidone5-hydroxytryptamine 3 receptortarget
Ziprasidone5-hydroxytryptamine receptor 5Atarget
ErlotinibEpidermal growth factor receptortarget
ErlotinibCytochrome P450 3A4enzyme
ErlotinibATP-binding cassette sub-family G member 2transporter
ErlotinibP-glycoprotein 1transporter
ErlotinibNuclear receptor subfamily 1 group I member 2target
ErlotinibCytochrome P450 3A5enzyme
ErlotinibCytochrome P450 1A1enzyme
ErlotinibCytochrome P450 1A2enzyme
ErlotinibCytochrome P450 1B1enzyme
ErlotinibCytochrome P450 2D6enzyme
ErlotinibCytochrome P450 2C8enzyme
ErlotinibUDP-glucuronosyltransferase 1-1enzyme
ErlotinibSerum albumincarrier
ErlotinibAlpha-1-acid glycoprotein 1carrier
ErlotinibSolute carrier organic anion transporter family member 2B1transporter
CilostazolcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
CilostazolCytochrome P450 2C19enzyme
CilostazolCytochrome P450 3A4enzyme
CilostazolCytochrome P450 3A5enzyme
CilostazolCytochrome P450 3A7enzyme
CilostazolCytochrome P450 1A2enzyme
CilostazolCytochrome P450 2D6enzyme
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineP-glycoprotein 1transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
MuraglitazarPeroxisome proliferator-activated receptor alphatarget
MuraglitazarPeroxisome proliferator-activated receptor gammatarget
MuraglitazarCytochrome P450 1A2enzyme
MuraglitazarUDP-glucuronosyltransferase 1-3enzyme
MuraglitazarUDP-glucuronosyltransferase 1-1enzyme
MuraglitazarCytochrome P450 2C8enzyme
VadimezanUDP-glucuronosyltransferase 1-9enzyme
VadimezanUDP-glucuronosyltransferase 2B7enzyme
VadimezanCytochrome P450 1A2enzyme
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
PazopanibVascular endothelial growth factor receptor 1target
PazopanibVascular endothelial growth factor receptor 2target
PazopanibVascular endothelial growth factor receptor 3target
PazopanibPlatelet-derived growth factor receptor alphatarget
PazopanibPlatelet-derived growth factor receptor betatarget
PazopanibMast/stem cell growth factor receptor Kittarget
PazopanibCytochrome P450 3A4enzyme
PazopanibCytochrome P450 2D6enzyme
PazopanibCytochrome P450 2C8enzyme
PazopanibCytochrome P450 1A2enzyme
PazopanibP-glycoprotein 1transporter
PazopanibATP-binding cassette sub-family G member 2transporter
PazopanibSolute carrier organic anion transporter family member 1B1transporter
PazopanibUDP-glucuronosyltransferase 1-1transporter
PazopanibFibroblast growth factor receptor 3target
PazopanibTyrosine-protein kinase ITK/TSKtarget
PazopanibFibroblast growth factor 1target
PazopanibSH2B adapter protein 3target
UlipristalProgesterone receptortarget
UlipristalGlucocorticoid receptortarget
UlipristalAndrogen receptortarget
UlipristalCytochrome P450 3A4enzyme
UlipristalCytochrome P450 1A2enzyme
UlipristalSerum albumincarrier
UlipristalAlpha-1-acid glycoprotein 1carrier
Lorcaserin5-hydroxytryptamine receptor 2Ctarget
LorcaserinCytochrome P450 1A2enzyme
LorcaserinCytochrome P450 2A6enzyme
LorcaserinCytochrome P450 2B6enzyme
LorcaserinCytochrome P450 2C19enzyme
LorcaserinCytochrome P450 2D6enzyme
LorcaserinCytochrome P450 3A4enzyme
LorcaserinDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
LorcaserinCytochrome P450 1A1enzyme
ApixabanCoagulation factor Xtarget
ApixabanCytochrome P450 3A4enzyme
ApixabanCytochrome P450 1A2enzyme
ApixabanCytochrome P450 2C8enzyme
ApixabanCytochrome P450 2C9enzyme
ApixabanCytochrome P450 2C19enzyme
ApixabanCytochrome P450 2J2enzyme
ApixabanP-glycoprotein 1transporter
ApixabanATP-binding cassette sub-family G member 2transporter
ApixabanCytochrome P450 3A5enzyme
AxitinibVascular endothelial growth factor receptor 1target
AxitinibVascular endothelial growth factor receptor 2target
AxitinibVascular endothelial growth factor receptor 3target
AxitinibCytochrome P450 3A4enzyme
AxitinibCytochrome P450 3A5enzyme
AxitinibCytochrome P450 1A2enzyme
AxitinibCytochrome P450 2C19enzyme
AxitinibUDP-glucuronosyltransferase 1-1enzyme
AxitinibP-glycoprotein 1transporter
AxitinibSolute carrier organic anion transporter family member 1B1transporter
PomalidomideCytochrome P450 1A2enzyme
PomalidomideCytochrome P450 3A4enzyme
PomalidomideP-glycoprotein 1transporter
PomalidomideProtein cereblontarget
PomalidomideTumor necrosis factortarget
PomalidomideProstaglandin G/H synthase 2target
IxazomibCytochrome P450 3A4enzyme
IxazomibCytochrome P450 1A2enzyme
IxazomibCytochrome P450 2B6enzyme
IxazomibCytochrome P450 2C8enzyme
IxazomibCytochrome P450 2D6enzyme
IxazomibCytochrome P450 2C19enzyme
IxazomibCytochrome P450 2C9enzyme
BendamustineCytochrome P450 1A2enzyme
RucaparibPoly [ADP-ribose] polymerase 1target
RucaparibPoly [ADP-ribose] polymerase 2target
RucaparibPoly [ADP-ribose] polymerase 3target
RucaparibCytochrome P450 2D6enzyme
RucaparibCytochrome P450 1A2enzyme
RucaparibCytochrome P450 3A4enzyme
RucaparibP-glycoprotein 1transporter
RucaparibATP-binding cassette sub-family G member 2transporter
RucaparibMultidrug and toxin extrusion protein 1transporter
RucaparibMultidrug and toxin extrusion protein 2transporter
RucaparibSolute carrier family 22 member 1transporter
RucaparibMultidrug resistance-associated protein 4transporter
RucaparibSolute carrier organic anion transporter family member 1B1transporter
RucaparibSolute carrier organic anion transporter family member 1B3transporter
RucaparibSolute carrier family 22 member 6transporter
RucaparibSolute carrier family 22 member 8transporter
RucaparibCytochrome P450 3A5enzyme
RucaparibCytochrome P450 3A7enzyme
RucaparibCytochrome P450 3A43enzyme
RucaparibCytochrome P450 2C19enzyme
RucaparibCytochrome P450 2C9enzyme
RucaparibCytochrome P450 2C8enzyme
RucaparibUDP-glucuronosyltransferase 1-1enzyme
IcotinibEpidermal growth factor receptortarget
IcotinibCytochrome P450 3A4enzyme
IcotinibCytochrome P450 1A2enzyme
IcotinibCytochrome P450 3A5enzyme
DeutetrabenazineSynaptic vesicular amine transportertarget
DeutetrabenazineCarbonyl reductase [NADPH] 1enzyme
DeutetrabenazineCarbonyl reductase [NADPH] 3enzyme
DeutetrabenazineCytochrome P450 2D6enzyme
DeutetrabenazineCytochrome P450 1A2enzyme
DeutetrabenazineCytochrome P450 3A5enzyme
DeutetrabenazineCytochrome P450 3A4enzyme
StiripentolCytochrome P450 2C19enzyme
StiripentolCytochrome P450 2D6enzyme
StiripentolCytochrome P450 3A4enzyme
StiripentolCytochrome P450 1A2enzyme
StiripentolCytochrome P450 2C9enzyme
StiripentolGABA(A) Receptortarget
StiripentolL-lactate dehydrogenase A chaintarget
StiripentolL-lactate dehydrogenase B chaintarget
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
EnasidenibCytochrome P450 1A2enzyme
EnasidenibCytochrome P450 2B6enzyme
EnasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
EnasidenibCytochrome P450 2C8enzyme
EnasidenibCytochrome P450 2C9enzyme
EnasidenibCytochrome P450 2C19enzyme
EnasidenibCytochrome P450 2D6enzyme
EnasidenibCytochrome P450 3A4enzyme
EnasidenibUDP-glucuronosyltransferase 1-1enzyme
EnasidenibUDP-glucuronosyltransferase 1-3enzyme
EnasidenibUDP-glucuronosyltransferase 1-4enzyme
EnasidenibUDP-glucuronosyltransferase 1-9enzyme
EnasidenibUDP-glucuronosyltransferase 2B7enzyme
EnasidenibUDP-glucuronosyltransferase 2B15enzyme
EnasidenibP-glycoprotein 1transporter
EnasidenibATP-binding cassette sub-family G member 2transporter
EnasidenibSolute carrier family 22 member 6transporter
EnasidenibSolute carrier organic anion transporter family member 1B1transporter
EnasidenibSolute carrier family 22 member 2transporter
EnasidenibSolute carrier organic anion transporter family member 1B3transporter
EnasidenibSolute carrier family 22 member 8transporter
Estradiol acetateEstrogen receptor alphatarget
Estradiol acetateNuclear receptor subfamily 1 group I member 2target
Estradiol acetateSex hormone-binding globulincarrier
Estradiol acetateEstrogen receptor betatarget
Estradiol acetateCytochrome P450 1A2enzyme
Estradiol acetateUDP-glucuronosyltransferase 1-1enzyme
Estradiol acetateSerum albumincarrier
Estradiol acetateFatty acid-binding protein, intestinalcarrier
Estradiol acetateCytochrome P450 3A4enzyme
Estradiol acetateCytochrome P450 3A5enzyme
Estradiol acetateCytochrome P450 3A7enzyme
Estradiol acetateSolute carrier family 22 member 2transporter
Estradiol acetateSolute carrier family 22 member 1transporter
Estradiol acetateSolute carrier family 22 member 3transporter
Estradiol acetateSolute carrier organic anion transporter family member 2B1transporter
Estradiol acetateSolute carrier organic anion transporter family member 1A2transporter
Estradiol acetateMultidrug resistance-associated protein 7transporter
Estradiol acetateSolute carrier family 22 member 11transporter
Estradiol acetateATP-binding cassette sub-family G member 2transporter
Estradiol acetateSolute carrier organic anion transporter family member 1B1transporter
Estradiol acetateP-glycoprotein 1transporter
Estradiol acetateCytochrome P450 1A1enzyme
Estradiol acetateCytochrome P450 1B1enzyme
Estradiol acetateCytochrome P450 2C19enzyme
Estradiol acetateCytochrome P450 2C8enzyme
Estradiol acetateCytochrome P450 2C9enzyme
Estradiol acetateSolute carrier family 22 member 8transporter
Estradiol acetateSolute carrier organic anion transporter family member 1B3transporter
Estradiol acetateSolute carrier organic anion transporter family member 1C1transporter
Estradiol acetateSolute carrier organic anion transporter family member 4A1transporter
Estradiol acetateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol acetateNuclear receptor coactivator 2target
Estradiol acetateG-protein coupled estrogen receptor 1target
Estradiol acetateATP synthase subunit atarget
Estradiol acetateBeclin-1target
Estradiol acetateEstradiol 17-beta-dehydrogenase 2target
Estradiol acetateEstrogen-related receptor gammatarget
Estradiol benzoateEstrogen receptor alphatarget
Estradiol benzoateNuclear receptor subfamily 1 group I member 2target
Estradiol benzoateSex hormone-binding globulincarrier
Estradiol benzoateEstrogen receptor betatarget
Estradiol benzoateCytochrome P450 1A2enzyme
Estradiol benzoateUDP-glucuronosyltransferase 1-1enzyme
Estradiol benzoateSerum albumincarrier
Estradiol benzoateFatty acid-binding protein, intestinalcarrier
Estradiol benzoateCytochrome P450 3A4enzyme
Estradiol benzoateCytochrome P450 3A5enzyme
Estradiol benzoateCytochrome P450 3A7enzyme
Estradiol benzoateSolute carrier family 22 member 2transporter
Estradiol benzoateSolute carrier family 22 member 1transporter
Estradiol benzoateSolute carrier family 22 member 3transporter
Estradiol benzoateSolute carrier organic anion transporter family member 2B1transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1A2transporter
Estradiol benzoateMultidrug resistance-associated protein 7transporter
Estradiol benzoateSolute carrier family 22 member 11transporter
Estradiol benzoateATP-binding cassette sub-family G member 2transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1B1transporter
Estradiol benzoateP-glycoprotein 1transporter
Estradiol benzoateCytochrome P450 1A1enzyme
Estradiol benzoateCytochrome P450 1B1enzyme
Estradiol benzoateCytochrome P450 2C19enzyme
Estradiol benzoateCytochrome P450 2C8enzyme
Estradiol benzoateCytochrome P450 2C9enzyme
Estradiol benzoateSolute carrier family 22 member 8transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1B3transporter
Estradiol benzoateSolute carrier organic anion transporter family member 1C1transporter
Estradiol benzoateSolute carrier organic anion transporter family member 4A1transporter
Estradiol benzoateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol benzoateNuclear receptor coactivator 2target
Estradiol benzoateG-protein coupled estrogen receptor 1target
Estradiol benzoateATP synthase subunit atarget
Estradiol benzoateBeclin-1target
Estradiol benzoateEstradiol 17-beta-dehydrogenase 2target
Estradiol benzoateEstrogen-related receptor gammatarget
Estradiol cypionateEstrogen receptor alphatarget
Estradiol cypionateNuclear receptor subfamily 1 group I member 2target
Estradiol cypionateSex hormone-binding globulincarrier
Estradiol cypionateEstrogen receptor betatarget
Estradiol cypionateCytochrome P450 1A2enzyme
Estradiol cypionateUDP-glucuronosyltransferase 1-1enzyme
Estradiol cypionateSerum albumincarrier
Estradiol cypionateFatty acid-binding protein, intestinalcarrier
Estradiol cypionateCytochrome P450 3A4enzyme
Estradiol cypionateCytochrome P450 3A5enzyme
Estradiol cypionateCytochrome P450 3A7enzyme
Estradiol cypionateSolute carrier family 22 member 2transporter
Estradiol cypionateSolute carrier family 22 member 1transporter
Estradiol cypionateSolute carrier family 22 member 3transporter
Estradiol cypionateSolute carrier organic anion transporter family member 2B1transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1A2transporter
Estradiol cypionateMultidrug resistance-associated protein 7transporter
Estradiol cypionateSolute carrier family 22 member 11transporter
Estradiol cypionateATP-binding cassette sub-family G member 2transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1B1transporter
Estradiol cypionateP-glycoprotein 1transporter
Estradiol cypionateCytochrome P450 1A1enzyme
Estradiol cypionateCytochrome P450 1B1enzyme
Estradiol cypionateCytochrome P450 2C19enzyme
Estradiol cypionateCytochrome P450 2C8enzyme
Estradiol cypionateCytochrome P450 2C9enzyme
Estradiol cypionateSolute carrier family 22 member 8transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1B3transporter
Estradiol cypionateSolute carrier organic anion transporter family member 1C1transporter
Estradiol cypionateSolute carrier organic anion transporter family member 4A1transporter
Estradiol cypionateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol cypionateNuclear receptor coactivator 2target
Estradiol cypionateG-protein coupled estrogen receptor 1target
Estradiol cypionateATP synthase subunit atarget
Estradiol cypionateBeclin-1target
Estradiol cypionateEstradiol 17-beta-dehydrogenase 2target
Estradiol cypionateEstrogen-related receptor gammatarget
Estradiol dienanthateEstrogen receptor alphatarget
Estradiol dienanthateNuclear receptor subfamily 1 group I member 2target
Estradiol dienanthateSex hormone-binding globulincarrier
Estradiol dienanthateEstrogen receptor betatarget
Estradiol dienanthateCytochrome P450 1A2enzyme
Estradiol dienanthateUDP-glucuronosyltransferase 1-1enzyme
Estradiol dienanthateSerum albumincarrier
Estradiol dienanthateFatty acid-binding protein, intestinalcarrier
Estradiol dienanthateCytochrome P450 3A4enzyme
Estradiol dienanthateCytochrome P450 3A5enzyme
Estradiol dienanthateCytochrome P450 3A7enzyme
Estradiol dienanthateSolute carrier family 22 member 2transporter
Estradiol dienanthateSolute carrier family 22 member 1transporter
Estradiol dienanthateSolute carrier family 22 member 3transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 2B1transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1A2transporter
Estradiol dienanthateMultidrug resistance-associated protein 7transporter
Estradiol dienanthateSolute carrier family 22 member 11transporter
Estradiol dienanthateATP-binding cassette sub-family G member 2transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1B1transporter
Estradiol dienanthateP-glycoprotein 1transporter
Estradiol dienanthateCytochrome P450 1A1enzyme
Estradiol dienanthateCytochrome P450 1B1enzyme
Estradiol dienanthateCytochrome P450 2C19enzyme
Estradiol dienanthateCytochrome P450 2C8enzyme
Estradiol dienanthateCytochrome P450 2C9enzyme
Estradiol dienanthateSolute carrier family 22 member 8transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1B3transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 1C1transporter
Estradiol dienanthateSolute carrier organic anion transporter family member 4A1transporter
Estradiol dienanthateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol dienanthateNuclear receptor coactivator 2target
Estradiol dienanthateG-protein coupled estrogen receptor 1target
Estradiol dienanthateATP synthase subunit atarget
Estradiol dienanthateBeclin-1target
Estradiol dienanthateEstradiol 17-beta-dehydrogenase 2target
Estradiol dienanthateEstrogen-related receptor gammatarget
Estradiol valerateEstrogen receptor alphatarget
Estradiol valerateNuclear receptor subfamily 1 group I member 2target
Estradiol valerateSex hormone-binding globulincarrier
Estradiol valerateEstrogen receptor betatarget
Estradiol valerateCytochrome P450 1A2enzyme
Estradiol valerateUDP-glucuronosyltransferase 1-1enzyme
Estradiol valerateSerum albumincarrier
Estradiol valerateFatty acid-binding protein, intestinalcarrier
Estradiol valerateCytochrome P450 3A4enzyme
Estradiol valerateCytochrome P450 3A5enzyme
Estradiol valerateCytochrome P450 3A7enzyme
Estradiol valerateSolute carrier family 22 member 2transporter
Estradiol valerateSolute carrier family 22 member 1transporter
Estradiol valerateSolute carrier family 22 member 3transporter
Estradiol valerateSolute carrier organic anion transporter family member 2B1transporter
Estradiol valerateSolute carrier organic anion transporter family member 1A2transporter
Estradiol valerateMultidrug resistance-associated protein 7transporter
Estradiol valerateSolute carrier family 22 member 11transporter
Estradiol valerateATP-binding cassette sub-family G member 2transporter
Estradiol valerateSolute carrier organic anion transporter family member 1B1transporter
Estradiol valerateP-glycoprotein 1transporter
Estradiol valerateCytochrome P450 1A1enzyme
Estradiol valerateCytochrome P450 1B1enzyme
Estradiol valerateCytochrome P450 2C19enzyme
Estradiol valerateCytochrome P450 2C8enzyme
Estradiol valerateCytochrome P450 2C9enzyme
Estradiol valerateSolute carrier family 22 member 8transporter
Estradiol valerateSolute carrier organic anion transporter family member 1B3transporter
Estradiol valerateSolute carrier organic anion transporter family member 1C1transporter
Estradiol valerateSolute carrier organic anion transporter family member 4A1transporter
Estradiol valerateNeuronal acetylcholine receptor subunit alpha-4target
Estradiol valerateNuclear receptor coactivator 2target
Estradiol valerateG-protein coupled estrogen receptor 1target
Estradiol valerateATP synthase subunit atarget
Estradiol valerateBeclin-1target
Estradiol valerateEstradiol 17-beta-dehydrogenase 2target
Estradiol valerateEstrogen-related receptor gammatarget
ZotepineD(1) dopamine receptortarget
ZotepineDopamine D2 receptortarget
Zotepine5-hydroxytryptamine receptor 2Atarget
Zotepine5-hydroxytryptamine receptor 6target
Zotepine5-hydroxytryptamine receptor 7target
ZotepineSodium-dependent noradrenaline transportertarget
ZotepineSodium-dependent serotonin transportertarget
ZotepineCytochrome P450 1A2enzyme
ZotepineCytochrome P450 3A4enzyme
LofexidineAlpha-2A adrenergic receptortarget
LofexidineAlpha-1A adrenergic receptortarget
Lofexidine5-hydroxytryptamine receptor 1Atarget
Lofexidine5-hydroxytryptamine receptor 7target
Lofexidine5-hydroxytryptamine receptor 2Ctarget
Lofexidine5-hydroxytryptamine receptor 1Dtarget
LofexidineCytochrome P450 2D6enzyme
LofexidineCytochrome P450 1A2enzyme
LofexidineCytochrome P450 2C19enzyme
LofexidineATP-binding cassette sub-family B member 5transporter
LofexidineMultidrug and toxin extrusion protein 1transporter
TasimelteonMelatonin receptor type 1Atarget
TasimelteonMelatonin receptor type 1Btarget
TasimelteonCytochrome P450 3A4enzyme
TasimelteonCytochrome P450 1A2enzyme
PirfenidoneFurintarget
PirfenidoneCytochrome P450 1A2enzyme
Ramosetron5-hydroxytryptamine receptor 3Atarget
RamosetronCytochrome P450 1A2enzyme
AcetaminophenProstaglandin G/H synthase 1target
AcetaminophenProstaglandin G/H synthase 2target
AcetaminophenCytochrome P450 1A2enzyme
AcetaminophenCytochrome P450 2E1enzyme
AcetaminophenP-glycoprotein 1transporter
AcetaminophenCytochrome P450 2D6enzyme
AcetaminophenCytochrome P450 2A6enzyme
AcetaminophenCytochrome P450 3A4enzyme
AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
AcetaminophenSulfotransferase 1A1enzyme
AcetaminophenSulfotransferase 1A3/1A4enzyme
AcetaminophenArylamine N-acetyltransferase 2enzyme
AcetaminophenProstaglandin E synthase 3target
AcetaminophenTransient receptor potential cation channel subfamily V member 1target
AcetaminophenSerum albumincarrier
AcetaminophenFatty-acid amide hydrolase 1enzyme
AcetaminophenGlutathione S-transferase Penzyme
AcetaminophenGlutathione S-transferase Mu 1enzyme
ClopidogrelP2Y purinoceptor 12target
ClopidogrelCytochrome P450 3A4enzyme
ClopidogrelCytochrome P450 2B6enzyme
ClopidogrelCytochrome P450 3A5enzyme
ClopidogrelCytochrome P450 2C19enzyme
ClopidogrelCytochrome P450 2C9enzyme
ClopidogrelCytochrome P450 1A2enzyme
ClopidogrelCytochrome P450 2C8enzyme
ClopidogrelLiver carboxylesterase 1enzyme
ClopidogrelP-glycoprotein 1transporter
ClopidogrelSolute carrier family 22 member 1transporter
ClopidogrelSolute carrier family 22 member 2transporter
FluvoxamineSodium-dependent serotonin transportertarget
FluvoxamineCytochrome P450 1A2enzyme
FluvoxamineCytochrome P450 2D6enzyme
FluvoxamineCytochrome P450 2C9enzyme
FluvoxamineCytochrome P450 2C19enzyme
FluvoxamineCytochrome P450 1A1enzyme
FluvoxamineCytochrome P450 3A4enzyme
FluvoxamineCytochrome P450 3A Subfamilyenzyme
FluvoxamineP-glycoprotein 1transporter
FluvoxamineCytochrome P450 2B6enzyme
FluvoxaminePotassium voltage-gated channel subfamily H member 2target
FluvoxamineBile salt export pumptransporter
TegafurCytochrome P450 2A6enzyme
TegafurThymidylate synthasetarget
TegafurCytochrome P450 1A2enzyme
TegafurCytochrome P450 2C8enzyme
TegafurCytochrome P450 2E1enzyme
TegafurCytochrome P450 3A5enzyme
TegafurThyroxine-binding globulincarrier
AmiodaroneBeta adrenergic receptortarget
AmiodaroneHERG human cardiac K+ channeltarget
AmiodaroneCytochrome P450 2C8enzyme
AmiodaroneCytochrome P450 2C9enzyme
AmiodaroneCytochrome P450 2D6enzyme
AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmiodaroneVoltage gated L-type calcium channeltarget
AmiodaroneCytochrome P450 3A4enzyme
AmiodaroneCytochrome P450 1A2enzyme
AmiodaroneCytochrome P450 1A1enzyme
AmiodaroneP-glycoprotein 1transporter
AmiodaroneCytochrome P450 2C19enzyme
AmiodaroneCytochrome P450 2A6enzyme
AmiodaroneThyroid hormone receptortarget
AmiodaronePeroxisome proliferator-activated receptor gammatarget
AmiodaroneBile salt export pumptransporter
AmiodaroneSolute carrier family 22 member 2transporter
AmiodaroneCytochrome P450 2J2enzyme
AmiodaronePeroxisome proliferator-activated receptor alphatarget
AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
AmiodaroneSerum albumincarrier
DihydralazineCytochrome P450 1A2enzyme
PimobendanCytochrome P450 1A2enzyme
RanitidineHistamine H2 receptortarget
RanitidineCytochrome P450 1A2enzyme
RanitidineCytochrome P450 2D6enzyme
RanitidineSolute carrier family 22 member 1transporter
RanitidineP-glycoprotein 1transporter
RanitidineSolute carrier family 22 member 8transporter
RanitidineCytochrome P450 3A4enzyme
RanitidineAcetylcholinesterasetarget
RanitidineSolute carrier family 22 member 2transporter
RanitidineAcetylcholinesteraseenzyme
PerampanelGlutamate receptor 1target
PerampanelCytochrome P450 3A4enzyme
PerampanelCytochrome P450 3A5enzyme
PerampanelCytochrome P450 1A2enzyme
PerampanelCytochrome P450 2B6enzyme
(R)-warfarinSerum albumincarrier
(R)-warfarinCytochrome P450 2C8enzyme
(R)-warfarinCytochrome P450 2C9enzyme
(R)-warfarinCytochrome P450 2C18enzyme
(R)-warfarinCytochrome P450 2C19enzyme
(R)-warfarinCytochrome P450 1A2enzyme
(R)-warfarinCytochrome P450 1A1enzyme
(R)-warfarinCytochrome P450 3A4enzyme
6-O-benzylguanineCytochrome P450 3A4enzyme
8-chlorotheophyllineAdenosine receptor A2atarget
8-chlorotheophyllineCytochrome P450 1A2enzyme
HypoxanthinePurine nucleoside phosphorylasetarget
HypoxanthineCytochrome P450 1A2enzyme
LisofyllineCytochrome P450 1A2enzyme
OxtriphyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
OxtriphyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
OxtriphyllineAdenosine receptor A2atarget
OxtriphyllineAdenosine receptor A1target
OxtriphyllineCytochrome P450 1A2enzyme
OxtriphyllineSolute carrier family 22 member 7transporter
OxtriphyllineHistone deacetylase 2target
XanthinePurine nucleoside phosphorylase 2target
XanthineXanthine phosphoribosyltransferasetarget
XanthineCytochrome P450 1A2enzyme
TemafloxacinDNA gyrase subunit Atarget
TemafloxacinDNA topoisomerase 4 subunit Atarget
TemafloxacinCytochrome P450 1A2enzyme
AcefyllineCytochrome P450 1A2enzyme
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
BamifyllineCytochrome P450 1A2enzyme
BromotheophyllineCytochrome P450 1A2enzyme
BufyllineCytochrome P450 1A2enzyme
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme
EntecavirDNAtarget
EtamiphyllineCytochrome P450 1A2enzyme
FenethyllineCytochrome P450 1A2enzyme
PeldesinePurine nucleoside phosphorylasetarget
PemetrexedThymidylate synthasetarget
PemetrexedDihydrofolate reductasetarget
PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
PemetrexedDeoxycytidine kinaseenzyme
PemetrexedBifunctional purine biosynthesis protein PURHtarget
PemetrexedEquilibrative nucleoside transporter 1enzyme
PemetrexedSolute carrier family 22 member 8transporter
PenciclovirDNA polymerase catalytic subunittarget
PenciclovirThymidine kinasetarget
PentifyllineCytochrome P450 1A2enzyme
PropentofyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
PropentofyllineCytochrome P450 1A2enzyme
ProxyphyllineCytochrome P450 1A2enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
NicotineNeuronal acetylcholine receptor subunit alpha-2target
NicotineNeuronal acetylcholine receptor subunit beta-2target
NicotineNeuronal acetylcholine receptor subunit alpha-7target
NicotineNeuronal acetylcholine receptor subunit alpha-4target
NicotineNeuronal acetylcholine receptor subunit alpha-10target
NicotineNeuronal acetylcholine receptor subunit alpha-9target
NicotineCytochrome P450 2A6enzyme
NicotineCytochrome P450 2E1enzyme
NicotineCytochrome P450 2A13enzyme
NicotineCytochrome P450 2B6enzyme
NicotineNeuronal acetylcholine receptor subunit beta-4target
NicotineNeuronal acetylcholine receptor subunit alpha-3target
NicotineNeuronal acetylcholine receptor subunit alpha-5target
NicotineNeuronal acetylcholine receptor subunit alpha-6target
NicotineNeuronal acetylcholine receptor subunit beta-3target
NicotineSolute carrier family 22 member 2transporter
NicotineSolute carrier family 22 member 1transporter
NicotineSolute carrier family 22 member 3transporter
NicotineSolute carrier family 22 member 5transporter
NicotineSolute carrier family 22 member 4transporter
NicotineCytochrome P450 1A1enzyme
NicotineCytochrome P450 1A2enzyme
NicotineCytochrome P450 2C19enzyme
NicotineCytochrome P450 2C8enzyme
NicotineCytochrome P450 2C9enzyme
NicotineCytochrome P450 2D6enzyme
NicotineCytochrome P450 3A4enzyme
NicotineAmine oxidase [flavin-containing] Aenzyme
NicotineAmine oxidase [flavin-containing] Benzyme
NicotineCytochrome P450 19A1target
NicotineCholine O-acetyltransferasetarget
CarmustineGlutathione reductase, mitochondrialtarget
CarmustineDNAtarget
CarmustineRNAtarget
LomefloxacinDNA gyrase subunit Atarget
LomefloxacinDNA topoisomerase 4 subunit Atarget
LomefloxacinDNA topoisomerase 2-alphatarget
LomefloxacinCytochrome P450 1A2enzyme
LomefloxacinSolute carrier family 22 member 5transporter
LomefloxacinCanalicular multispecific organic anion transporter 1transporter
HesperetinMicrosomal triglyceride transfer protein large subunittarget
HesperetinSterol O-acyltransferase 1target
HesperetinSterol O-acyltransferase 2target
HesperetinCytochrome P450 1A2enzyme
HesperetinATP-binding cassette sub-family G member 2transporter
HesperetinSex hormone-binding globulintarget
LeflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
LeflunomideCytochrome P450 1A2enzyme
LeflunomideCytochrome P450 2C9enzyme
LeflunomideAryl hydrocarbon receptortarget
LeflunomideProtein-tyrosine kinase 2-betatarget
LeflunomideATP-binding cassette sub-family G member 2transporter
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
ThiabendazoleFumarate reductase flavoprotein subunittarget
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleCytochrome P450 1A1enzyme
NifedipineCytochrome P450 3A4enzyme
NifedipineCytochrome P450 2E1enzyme
NifedipineCytochrome P450 2D6enzyme
NifedipineCalmodulintarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
NifedipinePotassium voltage-gated channel subfamily D member 3target
NifedipineVoltage-dependent T-type calcium channeltarget
NifedipineCytochrome P450 1A2enzyme
NifedipineCytochrome P450 2A6enzyme
NifedipineCytochrome P450 2C8enzyme
NifedipineCanalicular multispecific organic anion transporter 2transporter
NifedipineP-glycoprotein 1transporter
NifedipineCanalicular multispecific organic anion transporter 1transporter
NifedipineCytochrome P450 1A1enzyme
NifedipineCytochrome P450 2B6enzyme
NifedipineNuclear receptor subfamily 1 group I member 2target
NifedipineSolute carrier organic anion transporter family member 1B1transporter
NifedipineBile salt export pumptransporter
NifedipineCytochrome P450 2C9enzyme
NifedipineSerum albumincarrier
Nifedipinealpha1-acid glycoproteincarrier
NifedipineCytochrome P450 3A5enzyme
PrimaquineCytochrome P450 1A1enzyme
PrimaquineCytochrome P450 1A2enzyme
PrimaquineCytochrome P450 3A4enzyme
PrimaquineKeratin, type II cytoskeletal 7target
PrimaquineCytochrome P450 1B1enzyme
PrimaquineCytochrome P450 2D6enzyme
PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
PrimaquineFe(II)-protoporphyrin IXtarget
PrimaquineP-glycoprotein 1transporter
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
PraziquantelSchistosome calcium ion (Ca2+) channelstarget
PraziquantelCytochrome P450 3A4enzyme
PraziquantelCytochrome P450 1A2enzyme
PraziquantelCytochrome P450 2C19enzyme
PraziquantelCytochrome P450 3A43enzyme
PraziquantelCytochrome P450 3A5enzyme
PraziquantelCytochrome P450 3A7enzyme
TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
TriamtereneAmiloride-sensitive sodium channel subunit betatarget
TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
TriamtereneCytochrome P450 1A2enzyme
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
Benzyl alcoholCytochrome P450 2C8enzyme
Benzyl alcoholCytochrome P450 1A1enzyme
Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
Benzyl alcoholCytochrome P450 1A2enzyme
Benzyl alcoholCytochrome P450 2E1enzyme
Benzyl alcoholCytochrome P450 2D6enzyme
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
BinimetinibInterleukin-6target
BinimetinibTumor necrosis factortarget
BinimetinibInterleukin-1 betatarget
BinimetinibUDP-glucuronosyltransferase 1-1enzyme
BinimetinibCytochrome P450 1A2enzyme
BinimetinibCytochrome P450 2C19enzyme
BinimetinibMitogen-activated protein kinase kinase kinase 1target
BinimetinibDual specificity mitogen-activated protein kinase kinase 2target
AzathioprineThiopurine S-methyltransferaseenzyme
AzathioprineXanthine dehydrogenase/oxidaseenzyme
AzathioprineGlutathione S-transferase A1enzyme
AzathioprineGlutathione S-transferase A2enzyme
AzathioprineGlutathione S-transferase Mu 1enzyme
AzathioprineRas-related C3 botulinum toxin substrate 1target
AzathioprineCytochrome P450 1A2enzyme
AzathioprineHypoxanthine-guanine phosphoribosyltransferaseenzyme
AzathioprineNucleotide triphosphate diphosphatase NUDT15enzyme
AzathioprineEquilibrative nucleoside transporter 2transporter
AzathioprineSolute carrier family 28 member 3transporter
AzathioprineP-glycoprotein 1transporter
AzathioprineSolute carrier family 43 member 3transporter
AzathioprineSerum albumincarrier
AzathioprineInosine-5'-monophosphate dehydrogenase 1enzyme
AzathioprineInosine-5'-monophosphate dehydrogenase 2enzyme
AzathioprineGMP synthase [glutamine-hydrolyzing]enzyme
AzathioprineInosine triphosphate pyrophosphataseenzyme
8-azaguaninePurine nucleoside phosphorylasetarget
8-azaguanineCytochrome P450 1A2enzyme
9-DeazaguanineHypoxanthine-guanine phosphoribosyltransferasetarget
9-DeazaguanineCytochrome P450 1A2enzyme
9-MethylguanineDihydroneopterin aldolasetarget
9-MethylguanineCytochrome P450 1A2enzyme
DisopyramideSodium channel protein type 5 subunit alphatarget
DisopyramideAlpha-1-acid glycoprotein 1carrier
DisopyramideCytochrome P450 3A4enzyme
DisopyramideMuscarinic acetylcholine receptor M1target
DisopyramideMuscarinic acetylcholine receptor M2target
DisopyramideMuscarinic acetylcholine receptor M3target
DisopyramidePotassium voltage-gated channel subfamily D member 2target
DisopyramidePotassium voltage-gated channel subfamily D member 3target
DisopyramideSolute carrier family 22 member 2transporter
DisopyramideSolute carrier family 22 member 1transporter
DisopyramidePotassium voltage-gated channel subfamily H member 2target
DisopyramideAlpha-1-acid glycoprotein 2target
DisopyramideCytochrome P450 1A2enzyme
Alosetron5-hydroxytryptamine receptor 3Atarget
AlosetronCytochrome P450 1A2enzyme
AlosetronCytochrome P450 2C9enzyme
AlosetronCytochrome P450 3A4enzyme
AlosetronCytochrome P450 2E1enzyme
SorafenibSerine/threonine-protein kinase B-raftarget
SorafenibReceptor-type tyrosine-protein kinase FLT3target
SorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
SorafenibVascular endothelial growth factor receptor 3target
SorafenibPlatelet-derived growth factor receptor betatarget
SorafenibMast/stem cell growth factor receptor Kittarget
SorafenibVascular endothelial growth factor receptor 2target
SorafenibCytochrome P450 3A4enzyme
SorafenibUDP-glucuronosyltransferase 1-9enzyme
SorafenibCytochrome P450 2B6enzyme
SorafenibCytochrome P450 2C8enzyme
SorafenibCytochrome P450 3A5enzyme
SorafenibCytochrome P450 3A7enzyme
SorafenibCytochrome P450 2C9enzyme
SorafenibMultidrug resistance-associated protein 4transporter
SorafenibP-glycoprotein 1transporter
SorafenibCanalicular multispecific organic anion transporter 1transporter
SorafenibATP-binding cassette sub-family G member 2transporter
SorafenibCytochrome P450 1A2enzyme
SorafenibCytochrome P450 2C19enzyme
SorafenibCytochrome P450 2D6enzyme
SorafenibUDP-glucuronosyltransferase 1-1enzyme
SorafenibRalA-binding protein 1transporter
SorafenibFibroblast growth factor receptor 1target
SorafenibProto-oncogene tyrosine-protein kinase receptor Rettarget
SorafenibVascular endothelial growth factor receptor 1target
SorafenibSolute carrier organic anion transporter family member 1B1transporter
Agomelatine5-hydroxytryptamine receptor 2Ctarget
AgomelatineMelatonin receptor type 1Btarget
AgomelatineMelatonin receptor type 1Atarget
AgomelatineCytochrome P450 2C9enzyme
AgomelatineCytochrome P450 1A2enzyme
TocainideSodium channel protein type 5 subunit alphatarget
TocainideSerum albumincarrier
TocainideCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
DapagliflozinSodium/glucose cotransporter 2target
DapagliflozinCytochrome P450 1A1enzyme
DapagliflozinCytochrome P450 1A2enzyme
DapagliflozinCytochrome P450 2A6enzyme
DapagliflozinCytochrome P450 2C9enzyme
DapagliflozinCytochrome P450 2D6enzyme
DapagliflozinCytochrome P450 3A4enzyme
DapagliflozinUDP-glucuronosyltransferase 1-9enzyme
DapagliflozinUDP-glucuronosyltransferase 2B4enzyme
DapagliflozinUDP-glucuronosyltransferase 2B7enzyme
DapagliflozinP-glycoprotein 1transporter
ApremilastPhosphodiesterase isozyme 4target
ApremilastCytochrome P450 3A4enzyme
ApremilastCytochrome P450 2A6enzyme
ApremilastCytochrome P450 1A2enzyme
ApremilastP-glycoprotein 1transporter
ParoxetineSodium-dependent serotonin transportertarget
ParoxetineSodium-dependent noradrenaline transportertarget
Paroxetine5-hydroxytryptamine receptor 2Atarget
ParoxetineCytochrome P450 2D6enzyme
ParoxetineCytochrome P450 2C9enzyme
ParoxetineP-glycoprotein 1transporter
ParoxetineCytochrome P450 2B6enzyme
ParoxetineCytochrome P450 1A2enzyme
ParoxetineCytochrome P450 3A4enzyme
ParoxetineAlpha-1 adrenergic receptorstarget
ParoxetineAlpha-2 adrenergic receptorstarget
ParoxetineBeta adrenergic receptortarget
ParoxetineDopamine D2 receptortarget
ParoxetineHistamine H1 receptortarget
ParoxetineSerotonin Receptorstarget
ParoxetineMuscarinic acetylcholine receptortarget
Paroxetine5-hydroxytryptamine receptor 2Btarget
ParoxetineD(1) dopamine receptortarget
ParoxetineCytochrome P450 2C19enzyme
TamoxifenEstrogen receptor alphatarget
TamoxifenEstrogen receptor betatarget
TamoxifenCytochrome P450 2C9enzyme
TamoxifenCytochrome P450 3A4enzyme
TamoxifenCytochrome P450 2D6enzyme
TamoxifenCytochrome P450 2C8enzyme
TamoxifenCytochrome P450 2B6enzyme
TamoxifenLiver carboxylesterase 1enzyme
TamoxifenCytochrome P450 3A5enzyme
TamoxifenCytochrome P450 1A1enzyme
TamoxifenCytochrome P450 1B1enzyme
TamoxifenCytochrome P450 2C19enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
TamoxifenDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TamoxifenCytochrome P450 3A7enzyme
TamoxifenP-glycoprotein 1transporter
TamoxifenATP-binding cassette sub-family G member 2transporter
TamoxifenCytochrome P450 19A1enzyme
TamoxifenCytochrome P450 2A6enzyme
TamoxifenCytochrome P450 2E1enzyme
TamoxifenUDP-glucuronosyltransferase 1-10enzyme
TamoxifenSulfotransferase 1A1enzyme
TamoxifenCanalicular multispecific organic anion transporter 1transporter
Tamoxifen3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerasetarget
TamoxifenProtein kinase Ctarget
TamoxifenAndrogen receptortarget
TamoxifenPotassium voltage-gated channel subfamily H member 2target
TamoxifenNuclear receptor subfamily 1 group I member 2target
TamoxifenEstrogen-related receptor gammatarget
TamoxifenSex hormone-binding globulintarget
TamoxifenBile salt export pumptransporter
TamoxifenThyroxine-binding globulincarrier
TamoxifenBile salt sulfotransferaseenzyme
TamoxifenCytochrome P450 1A2enzyme
TamoxifenUDP-glucuronosyltransferase 2B7enzyme
TamoxifenUDP-glucuronosyltransferase 2B17enzyme
TamoxifenEstrogen sulfotransferaseenzyme
TamoxifenATP-binding cassette sub-family A member 1transporter
TamoxifenMitogen-activated protein kinase 8target
TamoxifenSerum albumincarrier
IstradefyllineCytochrome P450 1A1enzyme
IstradefyllineCytochrome P450 3A4enzyme
IstradefyllineCytochrome P450 3A5enzyme
IstradefyllineCytochrome P450 1A2enzyme
IstradefyllineCytochrome P450 2B6enzyme
IstradefyllineCytochrome P450 2C8enzyme
IstradefyllineCytochrome P450 2C9enzyme
IstradefyllineCytochrome P450 2C18enzyme
IstradefyllineCytochrome P450 2D6enzyme
IstradefyllineCytochrome P450 3A Subfamilyenzyme
IstradefyllineP-glycoprotein 1transporter
IstradefyllineAdenosine receptor A2atarget
IstradefyllineAdenosine receptor A1target
IstradefyllineSerum albumincarrier
Istradefyllinealpha1-acid glycoproteincarrier
IstradefyllineATP-binding cassette sub-family G member 2transporter
IstradefyllineSolute carrier organic anion transporter family member 1B1transporter
IstradefyllineSolute carrier organic anion transporter family member 1B3transporter
IstradefyllineSolute carrier family 22 member 6transporter
IstradefyllinePOU domain, class 2, transcription factor 2transporter
IstradefyllineMultidrug and toxin extrusion protein 1transporter
IstradefyllineMultidrug and toxin extrusion protein 2transporter
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
LoratadineHistamine H1 receptortarget
LoratadineCytochrome P450 3A4enzyme
LoratadineCytochrome P450 2C19enzyme
LoratadineCytochrome P450 2D6enzyme
LoratadineCytochrome P450 2C8enzyme
LoratadineP-glycoprotein 1transporter
LoratadinePotassium voltage-gated channel subfamily H member 2target
LoratadineBile salt export pumptransporter
LoratadineCytochrome P450 1A1enzyme
LoratadineCytochrome P450 1A2enzyme
LoratadineCytochrome P450 2B6enzyme
LoratadineCytochrome P450 2C9enzyme
LoratadineCytochrome P450 3A5enzyme
LoratadineUDP-glucuronosyltransferase 2B10enzyme
LoratadineUDP-glucuronosyltransferase 1-1enzyme
LoratadineUDP-glucuronosyltransferase 1-3enzyme
LoratadineUDP-glucuronosyltransferase 2B15enzyme
GTS-21Neuronal acetylcholine receptor subunit alpha-7target
GTS-21Cytochrome P450 1A2enzyme
GTS-21Cytochrome P450 2E1enzyme
BicifadineSodium-dependent noradrenaline transportertarget
BicifadineSodium-dependent serotonin transportertarget
BicifadineDopamine D2 receptortarget
BicifadineCytochrome P450 2D6enzyme
BicifadineAmine oxidase [flavin-containing] Benzyme
BicifadineCytochrome P450 1A2enzyme
BicifadineAmine oxidase [flavin-containing] Aenzyme
VortioxetineSodium-dependent serotonin transportertarget
Vortioxetine5-hydroxytryptamine receptor 3Atarget
Vortioxetine5-hydroxytryptamine receptor 7target
Vortioxetine5-hydroxytryptamine receptor 1Btarget
Vortioxetine5-hydroxytryptamine receptor 1Atarget
VortioxetineBeta-1 adrenergic receptortarget
VortioxetineSodium-dependent noradrenaline transportertarget
VortioxetineCytochrome P450 2D6enzyme
VortioxetineCytochrome P450 3A4enzyme
VortioxetineCytochrome P450 3A5enzyme
VortioxetineCytochrome P450 2C19enzyme
VortioxetineCytochrome P450 2C9enzyme
VortioxetineCytochrome P450 2A6enzyme
VortioxetineCytochrome P450 2C8enzyme
VortioxetineCytochrome P450 2B6enzyme
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
LetrozoleCytochrome P450 19A1target
LetrozoleCytochrome P450 3A4enzyme
LetrozoleCytochrome P450 2A6enzyme
LetrozoleCytochrome P450 19A1enzyme
LetrozoleCytochrome P450 2C19enzyme
LetrozoleUDP-glucuronosyltransferase 2B7enzyme
LetrozoleSerum albumincarrier
LetrozoleP-glycoprotein 1transporter
HalothaneGamma-aminobutyric acid receptor subunit alpha-1target
HalothaneGlycine receptor subunit alpha-1target
HalothaneCalcium-activated potassium channel subunit alpha-1target
HalothaneNADH-ubiquinone oxidoreductase chain 1target
HalothaneIntermediate conductance calcium-activated potassium channel protein 4target
HalothaneRhodopsintarget
HalothaneG protein-activated inward rectifier potassium channel 2target
HalothaneG protein-activated inward rectifier potassium channel 1target
HalothaneGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2target
HalothaneNeuropeptide S receptortarget
HalothaneCytochrome P450 2E1enzyme
HalothaneCytochrome P450 2A6enzyme
HalothaneCytochrome P450 3A4enzyme
HalothaneGlutamate receptor ionotropic, NMDA 3Atarget
HalothaneGlutamate receptor ionotropic, NMDA 3Btarget
HalothaneGlutamate receptor ionotropic, NMDA 2Atarget
HalothanePotassium channel subfamily K member 3target
HalothanePotassium channel subfamily K member 9target
HalothaneSerum albumincarrier
HalothaneCytochrome P450 2B6enzyme
HalothaneCytochrome P450 2C9enzyme
HalothaneGABA(A) Receptortarget
HalothanePlasma membrane calcium-transporting ATPasetarget
IfosfamideCytochrome P450 2B6enzyme
IfosfamideDNAtarget
IfosfamideCytochrome P450 3A4enzyme
IfosfamideCytochrome P450 3A5enzyme
IfosfamideCytochrome P450 2C9enzyme
IfosfamideCytochrome P450 2C8enzyme
IfosfamideCytochrome P450 2A6enzyme
IfosfamideCytochrome P450 2C19enzyme
IfosfamideCytochrome P450 2C18enzyme
IfosfamideProstaglandin G/H synthase 1enzyme
IfosfamideNuclear receptor subfamily 1 group I member 2target
Valproic acidHistone deacetylase 9target
Valproic acidShort/branched chain specific acyl-CoA dehydrogenase, mitochondrialtarget
Valproic acidCytochrome P450 2A6enzyme
Valproic acidCytochrome P450 2B6enzyme
Valproic acidCytochrome P450 2C9enzyme
Valproic acidSolute carrier family 22 member 5transporter
Valproic acidSolute carrier family 22 member 6transporter
Valproic acidSolute carrier family 22 member 8transporter
Valproic acidMonocarboxylate transporter 1transporter
Valproic acidSolute carrier family 22 member 7transporter
Valproic acidCytochrome P450 3A5enzyme
Valproic acidUDP-glucuronosyltransferase 1-9enzyme
Valproic acidProstaglandin G/H synthase 1enzyme
Valproic acidCytochrome P450 1A2enzyme
Valproic acidCytochrome P450 2C19enzyme
Valproic acidCytochrome P450 3A4enzyme
Valproic acidUDP-glucuronosyltransferase 1-4enzyme
Valproic acidUDP-glucuronosyltransferase 1-8enzyme
Valproic acidUDP-glucuronosyltransferase 1-10enzyme
Valproic acidUDP-glucuronosyltransferase 1-6enzyme
Valproic acidUDP-glucuronosyltransferase 1-3enzyme
Valproic acidUDP-glucuronosyltransferase 2B7enzyme
Valproic acidUDP-glucuronosyltransferase 2B15enzyme
Valproic acid2-oxoglutarate dehydrogenase, mitochondrialtarget
Valproic acidSuccinate-semialdehyde dehydrogenase, mitochondrialtarget
Valproic acidSodium channel proteintarget
Valproic acidHistone deacetylase 2target
Valproic acidPeroxisome proliferator-activated receptor alphatarget
Valproic acidPeroxisome proliferator-activated receptor deltatarget
Valproic acidPeroxisome proliferator-activated receptor gammatarget
Valproic acidSerum albumincarrier
Valproic acidUDP-glucuronosyltransferase 1-1enzyme
Valproic acidSolute carrier organic anion transporter family member 2B1transporter
NevirapineCytochrome P450 3A4enzyme
NevirapineCytochrome P450 2B6enzyme
NevirapineCytochrome P450 3A5enzyme
NevirapineCytochrome P450 2C9enzyme
NevirapineCytochrome P450 2A6enzyme
NevirapineCytochrome P450 2D6enzyme
NevirapineReverse transcriptase/RNaseHtarget
NevirapineSerum albumincarrier
NevirapineCytochrome P450 1A2enzyme
NevirapineSolute carrier family 22 member 1transporter
NevirapineCytochrome P450 3A7enzyme
MontelukastCysteinyl leukotriene receptor 1target
MontelukastArachidonate 5-lipoxygenasetarget
MontelukastCytochrome P450 3A4enzyme
MontelukastCytochrome P450 2C9enzyme
MontelukastCytochrome P450 2C8enzyme
MontelukastSolute carrier organic anion transporter family member 2B1transporter
MontelukastProstaglandin G/H synthase 1enzyme
MontelukastCytochrome P450 2A6enzyme
Cisapride5-hydroxytryptamine receptor 4target
Cisapride5-hydroxytryptamine receptor 3Atarget
CisapridePotassium voltage-gated channel subfamily H member 2target
Cisapride5-hydroxytryptamine receptor 2Atarget
CisaprideCytochrome P450 3A4enzyme
CisaprideCytochrome P450 3A5enzyme
CisaprideCytochrome P450 3A7enzyme
CisaprideCytochrome P450 2A6enzyme
CisaprideCytochrome P450 2B6enzyme
CisaprideCytochrome P450 2C19enzyme
CisaprideCytochrome P450 2C8enzyme
CisaprideCytochrome P450 2C9enzyme
CisaprideCytochrome P450 2D6enzyme
ClomethiazoleGamma-aminobutyric acid receptor subunit alpha-1target
ClomethiazoleCytochrome P450 2A6enzyme
ClomethiazoleCytochrome P450 2B6enzyme
ClomethiazoleCytochrome P450 2C19enzyme
ClomethiazoleCytochrome P450 3A4enzyme
CyclophosphamideDNAtarget
CyclophosphamideCytochrome P450 2B6enzyme
CyclophosphamideCytochrome P450 2C9enzyme
CyclophosphamideCytochrome P450 3A4enzyme
CyclophosphamideCytochrome P450 2C19enzyme
CyclophosphamideCytochrome P450 2A6enzyme
CyclophosphamideCytochrome P450 2C18enzyme
CyclophosphamideCytochrome P450 2C8enzyme
CyclophosphamideCytochrome P450 3A5enzyme
CyclophosphamideNuclear receptor subfamily 1 group I member 2target
FlunitrazepamCytochrome P450 2C19enzyme
FlunitrazepamUDP-glucuronosyltransferase 2B7enzyme
FlunitrazepamCytochrome P450 2A6enzyme
FlunitrazepamCytochrome P450 2B6enzyme
FlunitrazepamCytochrome P450 2C9enzyme
FlunitrazepamCytochrome P450 3A4enzyme
FlunitrazepamCytochrome P450 2E1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-1enzyme
FlunitrazepamUDP-glucuronosyltransferase 1-3enzyme
FlunitrazepamGABA(A) Receptortarget
FlunitrazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
SevofluraneCalcium-transporting ATPase type 2C member 1target
SevofluraneNADH-ubiquinone oxidoreductase chain 1target
SevofluraneGlycine receptor subunit alpha-1target
SevofluraneGlutamate receptor 1target
SevofluraneGamma-aminobutyric acid receptor subunit alpha-1target
SevofluraneCytochrome P450 2E1enzyme
SevofluraneSerum albumincarrier
SevofluraneCytochrome P450 2A6enzyme
SevofluraneCytochrome P450 2B6enzyme
SevofluraneCytochrome P450 3A4enzyme
SevofluraneGABA(A) Receptortarget
SevofluraneMitochondrial potassium channeltarget
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
FlurazepamCytochrome P450 3A4enzyme
FlurazepamP-glycoprotein 1transporter
FlurazepamCytochrome P450 2E1enzyme
FlurazepamCytochrome P450 2A6enzyme
FlurazepamSolute carrier family 22 member 2transporter
FlurazepamGABA(A) Receptortarget
FlurazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
TretinoinRetinoic acid receptor gammatarget
TretinoinRetinoic acid receptor RXR-betatarget
TretinoinRetinal dehydrogenase 1target
TretinoinRetinoic acid-induced protein 3target
TretinoinRetinoic acid receptor RXR-gammatarget
TretinoinRetinal dehydrogenase 2target
TretinoinRetinoic acid receptor responder protein 1target
TretinoinCytochrome P450 2C8enzyme
TretinoinCellular retinoic acid-binding protein 1transporter
TretinoinCellular retinoic acid-binding protein 2transporter
TretinoinCytochrome P450 2B6enzyme
TretinoinCytochrome P450 3A4enzyme
TretinoinCytochrome P450 3A5enzyme
TretinoinCytochrome P450 2A6enzyme
TretinoinCytochrome P450 3A7enzyme
TretinoinCytochrome P450 2C18enzyme
TretinoinCytochrome P450 2C9enzyme
TretinoinCytochrome P450 4A11enzyme
TretinoinCytochrome P450 1A1enzyme
TretinoinRetinoic acid receptor alphatarget
TretinoinRetinoic acid receptor betatarget
TretinoinLipocalin-1target
TretinoinOdorant-binding protein 2atarget
TretinoinRetinol-binding protein 4target
TretinoinSerum albumincarrier
Tretinoin[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrialtarget
TretinoinRetinoic acid receptor RXR-alphatarget
TretinoinCytochrome P450 26A1target
TretinoinCytochrome P450 26B1target
TretinoinCytochrome P450 26C1target
TretinoinHematopoietic prostaglandin D synthasetarget
ArformoterolBeta-2 adrenergic receptortarget
ArformoterolCytochrome P450 2D6enzyme
ArformoterolCytochrome P450 2C19enzyme
ArformoterolCytochrome P450 2A6enzyme
ArformoterolCytochrome P450 2C9enzyme
Tegafur-uracilCytochrome P450 2A6enzyme
Tegafur-uracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
Tegafur-uracilDihydropyrimidine dehydrogenase [NADP(+)]target
Tegafur-uracilThymidylate synthasetarget
Tegafur-uracilRNAtarget
Tegafur-uracilDNAtarget
Tegafur-uracilSolute carrier family 22 member 7transporter
Tegafur-uracilEquilibrative nucleoside transporter 1transporter
Tegafur-uracilEquilibrative nucleoside transporter 2transporter
Tegafur-uracilSodium/nucleoside cotransporter 1transporter
Tegafur-uracilSodium/nucleoside cotransporter 2transporter
Tegafur-uracilSolute carrier family 28 member 3transporter
AsunaprevirGenome polyproteintarget
AsunaprevirCytochrome P450 3A4enzyme
AsunaprevirCytochrome P450 3A5enzyme
AsunaprevirCytochrome P450 2A6enzyme
AsunaprevirCytochrome P450 2B6enzyme
AsunaprevirCytochrome P450 2C9enzyme
AsunaprevirCytochrome P450 2C19enzyme
AsunaprevirCytochrome P450 2D6enzyme
AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
AsunaprevirP-glycoprotein 1transporter
ArtesunateMalaria protein EXP-1target
ArtesunateCytochrome P450 2A6enzyme
ArtesunateUDP-glucuronosyltransferase 2B7enzyme
ArtesunateUDP-glucuronosyltransferase 1-9enzyme
ArtesunateATP-binding cassette sub-family G member 2transporter
ArtesunateP-glycoprotein 1transporter
ArtesunateSolute carrier organic anion transporter family member 1B1transporter
ArtesunateSolute carrier family 22 member 8transporter
ArtesunateSerum albumincarrier
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
PlitidepsinCytochrome P450 3A4enzyme
PlitidepsinCytochrome P450 2A6enzyme
PlitidepsinCytochrome P450 2E1enzyme
PlitidepsinCytochrome P450 4A11enzyme
BupropionSodium-dependent dopamine transportertarget
BupropionSodium-dependent noradrenaline transportertarget
BupropionCytochrome P450 2B6enzyme
BupropionCytochrome P450 2D6enzyme
BupropionAlpha-1-acid glycoprotein 1carrier
BupropionNeuronal acetylcholine receptor subunit alpha-3target
BupropionCytochrome P450 2C9enzyme
BupropionCytochrome P450 2E1enzyme
BupropionSolute carrier family 22 member 2transporter
Bupropion5-hydroxytryptamine receptor 3Atarget
MeperidineKappa-type opioid receptortarget
MeperidineCytochrome P450 2D6enzyme
MeperidineCytochrome P450 2B6enzyme
MeperidineGlutamate receptor ionotropic, NMDA 1target
MeperidineGlutamate receptor ionotropic, NMDA 2Btarget
MeperidineGlutamate receptor ionotropic, NMDA 2Atarget
MeperidineGlutamate receptor ionotropic, NMDA 2Ctarget
MeperidineGlutamate receptor ionotropic, NMDA 2Dtarget
MeperidineCytochrome P450 2C19enzyme
MeperidineCytochrome P450 3A4enzyme
MeperidineSerum albumincarrier
MeperidineAlpha-1-acid glycoprotein 1carrier
MeperidineMuscarinic acetylcholine receptortarget
MeperidineMu-type opioid receptortarget
MeperidineSodium-dependent dopamine transportertarget
MeperidineSodium-dependent noradrenaline transportertarget
MeperidineSodium-dependent serotonin transportertarget
MeperidineLiver carboxylesterase 1target
MeperidineCytochrome P450 1A2enzyme
MeperidineP-glycoprotein 1transporter
PropofolCytochrome P450 2B6enzyme
PropofolUDP-glucuronosyltransferase 1-1enzyme
PropofolUDP-glucuronosyltransferase 1-9enzyme
PropofolGamma-aminobutyric acid receptor subunit beta-2target
PropofolGamma-aminobutyric acid receptor subunit beta-3target
PropofolSerum albumincarrier
PropofolSodium channel protein type 4 subunit alphatarget
PropofolSodium channel protein type 2 subunit alphatarget
PropofolFatty-acid amide hydrolase 1enzyme
PropofolCytochrome P450 2C9enzyme
PropofolUDP-glucuronosyltransferase 1-8enzyme
PropofolCytochrome P450 2E1enzyme
PropofolCytochrome P450 1B1enzyme
PropofolCytochrome P450 1A1enzyme
PropofolCytochrome P450 1A2enzyme
PropofolCytochrome P450 2C18enzyme
PropofolCytochrome P450 2C19enzyme
PropofolCytochrome P450 2C8enzyme
PropofolUDP-glucuronosyltransferase 1-6enzyme
PropofolGABA(A) Receptortarget
PropofolP-glycoprotein 1transporter
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineCholinesterasetarget
KetamineNitric oxide synthase, braintarget
Dosulepin5-hydroxytryptamine receptor 1Atarget
Dosulepin5-hydroxytryptamine receptor 2Atarget
DosulepinCytochrome P450 2D6enzyme
DosulepinCytochrome P450 1A2enzyme
DosulepinCytochrome P450 2C19enzyme
DosulepinCytochrome P450 2C9enzyme
DosulepinHistamine H1 receptortarget
DosulepinMuscarinic acetylcholine receptor M1target
DosulepinMuscarinic acetylcholine receptor M2target
DosulepinMuscarinic acetylcholine receptor M3target
DosulepinMuscarinic acetylcholine receptor M4target
DosulepinMuscarinic acetylcholine receptor M5target
DosulepinSodium-dependent noradrenaline transportertarget
DosulepinSodium-dependent serotonin transportertarget
DosulepinAlpha-1 adrenergic receptorstarget
DosulepinAlpha-2 adrenergic receptorstarget
TrimipramineSodium-dependent serotonin transportertarget
TrimipramineSodium-dependent noradrenaline transportertarget
TrimipramineCytochrome P450 2D6enzyme
TrimipramineSodium-dependent dopamine transportertarget
Trimipramine5-hydroxytryptamine receptor 2Atarget
Trimipramine5-hydroxytryptamine receptor 1Atarget
TrimipramineAlpha-1A adrenergic receptortarget
TrimipramineAlpha-1B adrenergic receptortarget
TrimipramineDopamine D2 receptortarget
TrimipramineAlpha-2B adrenergic receptortarget
TrimipramineHistamine H1 receptortarget
TrimipramineCytochrome P450 2C19enzyme
TrimipramineP-glycoprotein 1transporter
TrimipramineCytochrome P450 2C9enzyme
Trimipramine5-hydroxytryptamine receptor 2Ctarget
Trimipramine5-hydroxytryptamine receptor 3Atarget
Trimipramine5-hydroxytryptamine receptor 1Dtarget
TrimipramineAlpha-2A adrenergic receptortarget
TrimipramineD(1) dopamine receptortarget
TrimipramineBeta adrenergic receptortarget
TrimipramineMuscarinic acetylcholine receptortarget
Trimipramine5-hydroxytryptamine receptor 1Ctarget
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
LoperamideVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
LoperamideMu-type opioid receptortarget
LoperamideCalmodulintarget
LoperamidePro-opiomelanocortintarget
LoperamideDelta-type opioid receptortarget
LoperamideCytochrome P450 3A4enzyme
LoperamideP-glycoprotein 1transporter
LoperamideKappa-type opioid receptortarget
LoperamideCytochrome P450 2C8enzyme
LoperamideCytochrome P450 2B6enzyme
LoperamideCytochrome P450 2D6enzyme
LoperamideNuclear receptor subfamily 1 group I member 3target
PerhexilineCarnitine O-palmitoyltransferase 1, liver isoformtarget
PerhexilineCarnitine O-palmitoyltransferase 2, mitochondrialtarget
PerhexilineCytochrome P450 2D6enzyme
PerhexilineCytochrome P450 2B6enzyme
PerhexilineCytochrome P450 3A4enzyme
PerhexilinePotassium voltage-gated channel subfamily H member 2target
TramadolMu-type opioid receptortarget
TramadolSodium-dependent noradrenaline transportertarget
Tramadol5-hydroxytryptamine receptor 2Ctarget
TramadolKappa-type opioid receptortarget
TramadolSodium-dependent serotonin transportertarget
TramadolCytochrome P450 2D6enzyme
TramadolDelta-type opioid receptortarget
TramadolCytochrome P450 3A4enzyme
TramadolCytochrome P450 2B6enzyme
TramadolAlpha-7 nicotinic cholinergic receptor subunittarget
TramadolMuscarinic acetylcholine receptor M3target
TramadolMuscarinic acetylcholine receptor M1target
TramadolUDP-glucuronosyltransferase 1-1enzyme
TramadolNeurokinin 1 receptortarget
TramadolSodium channel protein type 2 subunit alphatarget
TramadolTransient receptor potential cation channel subfamily V member 1target
TramadolNMDA receptortarget
TramadolAdenosine receptor A1target
TramadolAlpha-2 adrenergic receptorstarget
SertralineSodium-dependent serotonin transportertarget
SertralineCytochrome P450 2B6enzyme
SertralineCytochrome P450 2C19enzyme
SertralineCytochrome P450 2C9enzyme
SertralineCytochrome P450 2D6enzyme
SertralineSodium-dependent dopamine transportertarget
SertralineCYP2B proteinenzyme
SertralineCytochrome P450 3A4enzyme
SertralineAmine oxidase [flavin-containing] Benzyme
SertralineAmine oxidase [flavin-containing] Aenzyme
SertralineP-glycoprotein 1transporter
SertralineSerum albumincarrier
SertralineSigma receptortarget
SertralineSodium-dependent noradrenaline transportertarget
SertralineEquilibrative nucleoside transporter 4target
SertralineCytochrome P450 2E1enzyme
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
MethylphenobarbitalCytochrome P450 2C19enzyme
MethylphenobarbitalCytochrome P450 2B6enzyme
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
MethylphenobarbitalGlutamate receptor 2target
MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
IrinotecanDNA topoisomerase I, mitochondrialtarget
IrinotecanDNA topoisomerase 1target
IrinotecanCytochrome P450 3A4enzyme
IrinotecanCytochrome P450 3A5enzyme
IrinotecanUDP-glucuronosyltransferase 1-1enzyme
IrinotecanUDP-glucuronosyltransferase 1-9enzyme
IrinotecanLiver carboxylesterase 1enzyme
IrinotecanCytochrome P450 3A7enzyme
IrinotecanCytochrome P450 2B6enzyme
IrinotecanSolute carrier family 22 member 3transporter
IrinotecanSolute carrier organic anion transporter family member 1B1transporter
IrinotecanMultidrug resistance-associated protein 1transporter
IrinotecanATP-binding cassette sub-family G member 2transporter
IrinotecanSerum albumincarrier
IrinotecanCocaine esteraseenzyme
IrinotecanCholinesteraseenzyme
IrinotecanP-glycoprotein 1transporter
IrinotecanCanalicular multispecific organic anion transporter 1transporter
PromethazineDopamine D2 receptortarget
PromethazineHistamine H1 receptortarget
PromethazineMuscarinic acetylcholine receptor M4target
PromethazineMuscarinic acetylcholine receptor M1target
PromethazineMuscarinic acetylcholine receptor M5target
PromethazineMuscarinic acetylcholine receptor M2target
PromethazineMuscarinic acetylcholine receptor M3target
PromethazineCalmodulintarget
PromethazineCytochrome P450 2D6enzyme
PromethazineCytochrome P450 2B6enzyme
PromethazineP-glycoprotein 1transporter
PromethazineCytochrome P450 2C9enzyme
PromethazineHistamine H2 receptortarget
PromethazineAlpha adrenergic receptortarget
PromethazineP2 Purinoceptorstarget
PromethazineVoltage-gated sodium channel alpha subunittarget
PromethazineVoltage-gated Potassium Channelstarget
PromethazineCanalicular multispecific organic anion transporter 2transporter
PromethazineMultidrug resistance-associated protein 4transporter
PromethazineSerum albumincarrier
SeratrodastCytochrome P450 2C9enzyme
SeratrodastCytochrome P450 3A4enzyme
SeratrodastCytochrome P450 2C8enzyme
SeratrodastCytochrome P450 2C19enzyme
SeratrodastCytochrome P450 2B6enzyme
SeratrodastUDP-glucuronosyltransferase 1-9enzyme
SeratrodastProstaglandin G/H synthase 1enzyme
SeratrodastCytochrome P450 2A6enzyme
SeratrodastThromboxane A2 receptortarget
DextromethorphanSigma non-opioid intracellular receptor 1target
DextromethorphanHCG20471, isoform CRA_ctarget
DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DextromethorphanSodium-dependent serotonin transportertarget
DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DextromethorphanCytochrome P450 2D6enzyme
DextromethorphanCytochrome P450 3A4enzyme
DextromethorphanCytochrome P450 3A7enzyme
DextromethorphanCytochrome P450 2C9enzyme
DextromethorphanCytochrome P450 2B6enzyme
DextromethorphanCytochrome P450 2C19enzyme
DextromethorphanMembrane-associated progesterone receptor component 1target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DextromethorphanMu-type opioid receptortarget
DextromethorphanDelta-type opioid receptortarget
DextromethorphanKappa-type opioid receptortarget
DextromethorphanNADPH oxidasetarget
DextromethorphanSodium-dependent noradrenaline transportertarget
DextromethorphanUDP-glucuronosyltransferase 2B4enzyme
DextromethorphanUDP-glucuronosyltransferase 2B7enzyme
DextromethorphanUDP-glucuronosyltransferase 2B15enzyme
DextromethorphanUDP-glucuronosyltransferase 2B17enzyme
BenzphetamineAlpha-2A adrenergic receptortarget
BenzphetamineAlpha-1A adrenergic receptortarget
BenzphetamineCytochrome P450 3A4enzyme
BenzphetamineCytochrome P450 2B6enzyme
BenzphetamineNADPH--cytochrome P450 reductaseenzyme
BenzphetamineSynaptic vesicular amine transportertarget
BenzphetamineSodium-dependent dopamine transportertarget
ArtemetherCytochrome P450 3A4enzyme
ArtemetherCytochrome P450 3A5enzyme
ArtemetherCytochrome P450 2B6enzyme
ArtemetherCytochrome P450 2C9enzyme
ArtemetherCytochrome P450 2C19enzyme
BrompheniramineHistamine H1 receptortarget
BrompheniramineMuscarinic acetylcholine receptor M1target
BrompheniramineMuscarinic acetylcholine receptor M2target
BrompheniramineMuscarinic acetylcholine receptor M3target
BrompheniramineMuscarinic acetylcholine receptor M4target
BrompheniramineMuscarinic acetylcholine receptor M5target
ClobazamCytochrome P450 2C19enzyme
ClobazamCytochrome P450 3A4enzyme
ClobazamCytochrome P450 2B6enzyme
ClobazamCytochrome P450 2C18enzyme
ClobazamSodium- and chloride-dependent GABA transporter 1transporter
ClobazamSodium- and chloride-dependent GABA transporter 3transporter
ClobazamP-glycoprotein 1transporter
ClobazamGABA(A) Receptortarget
ClobazamCytochrome P450 2D6enzyme
ClobazamGABA(A) Receptor Benzodiazepine Binding Sitetarget
ClotiazepamCytochrome P450 2B6enzyme
ClotiazepamCytochrome P450 2C18enzyme
ClotiazepamCytochrome P450 2C19enzyme
ClotiazepamCytochrome P450 3A4enzyme
ClotiazepamGABA(A) Receptortarget
ClotiazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
EpinastineHistamine H1 receptortarget
EpinastineHistamine H2 receptortarget
EpinastineAlpha-1A adrenergic receptortarget
EpinastineAlpha-2A adrenergic receptortarget
Epinastine5-hydroxytryptamine receptor 2Atarget
Epinastine5-hydroxytryptamine receptor 7target
EpinastineP-glycoprotein 1transporter
EpinastineCytochrome P450 2B6enzyme
EpinastineCytochrome P450 2D6enzyme
EpinastineCytochrome P450 3A4enzyme
EthylmorphineCytochrome P450 2D6enzyme
EthylmorphineNADPH--cytochrome P450 reductaseenzyme
EthylmorphineMu-type opioid receptortarget
EthylmorphineCytochrome P450 2B6enzyme
EthylmorphineCytochrome P450 3A4enzyme
IsofluraneCalcium-transporting ATPase type 2C member 1target
IsofluraneATP synthase subunit delta, mitochondrialtarget
IsofluraneGamma-aminobutyric acid receptor subunit alpha-1target
IsofluranePotassium voltage-gated channel subfamily A member 1target
IsofluraneGlutamate receptor 1target
IsofluraneGlycine receptor subunit alpha-1target
IsofluraneCalmodulintarget
IsofluraneCytochrome P450 2E1enzyme
IsofluraneSerum albumincarrier
IsofluraneCytochrome P450 2B6enzyme
IsofluraneNADH-ubiquinone oxidoreductase chain 1enzyme
IsofluraneGABA(A) Receptortarget
IsofluraneNeuronal acetylcholine receptor subunit alpha-4target
IsofluraneNeuronal acetylcholine receptor subunit beta-2target
KetobemidoneProstaglandin G/H synthase 1enzyme
KetobemidoneCytochrome P450 2C9enzyme
KetobemidoneCytochrome P450 3A4enzyme
KetobemidoneUDP-glucuronosyltransferase 1-9enzyme
KetobemidoneCytochrome P450 2B6enzyme
KetobemidoneCytochrome P450 2C19enzyme
KetobemidoneCytochrome P450 2C8enzyme
KetobemidoneMu-type opioid receptortarget
KetobemidoneKappa-type opioid receptortarget
KetobemidoneDelta-type opioid receptortarget
KetobemidoneNMDA receptortarget
MethyltestosteroneCytochrome P450 2B6enzyme
MethyltestosteroneCytochrome P450 3A4enzyme
MethyltestosteroneAndrogen receptortarget
MethyltestosteroneSolute carrier organic anion transporter family member 1A2transporter
MethyltestosteroneSolute carrier family 22 member 8transporter
MethyltestosteroneSerum albumincarrier
MethyltestosteroneSex hormone-binding globulincarrier
MethyltestosteroneEstrogen receptor alphatarget
MethyltestosteroneCytochrome P450 19A1enzyme
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
TemazepamCytochrome P450 3A4enzyme
TemazepamCytochrome P450 2B6enzyme
TemazepamCytochrome P450 2C9enzyme
TemazepamGABA(A) Receptortarget
TemazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
TestosteroneAndrogen receptortarget
TestosteroneCytochrome P450 3A4enzyme
TestosteroneCytochrome P450 19A1enzyme
TestosteroneAmine oxidase [flavin-containing] Aenzyme
TestosteroneCholesterol side-chain cleavage enzyme, mitochondrialenzyme
TestosteroneSerum albumincarrier
TestosteroneSex hormone-binding globulincarrier
TestosteroneCytochrome P450 3A5enzyme
TestosteroneCytochrome P450 3A7enzyme
TestosteroneSolute carrier family 22 member 8transporter
TestosteroneSolute carrier family 22 member 7transporter
TestosteroneSodium/bile acid cotransportertransporter
TestosteroneATP-binding cassette sub-family G member 2transporter
TestosteroneCytochrome P450 1A1enzyme
TestosteroneCytochrome P450 1B1enzyme
TestosteroneCytochrome P450 2A13enzyme
TestosteroneCytochrome P450 2B6enzyme
TestosteroneCytochrome P450 2C19enzyme
TestosteroneCytochrome P450 2C8enzyme
TestosteroneCytochrome P450 2C9enzyme
TestosteroneCytochrome P450 3A43enzyme
TestosteroneEstrogen receptor alphatarget
TestosteroneMineralocorticoid receptortarget
TestosteroneSolute carrier organic anion transporter family member 1B3transporter
BanoxantroneDNA topoisomerase 2-alphatarget
BanoxantroneCytochrome P450 3A4enzyme
BanoxantroneCytochrome P450 1A1enzyme
BanoxantroneCytochrome P450 2B6enzyme
PrasugrelP2Y purinoceptor 12target
PrasugrelCocaine esteraseenzyme
PrasugrelCytochrome P450 3A4enzyme
PrasugrelCytochrome P450 2B6enzyme
PrasugrelCytochrome P450 2C9enzyme
PrasugrelCytochrome P450 2C19enzyme
PrasugrelSerum albumincarrier
OspemifeneEstrogen receptor alphatarget
OspemifeneCytochrome P450 3A4enzyme
OspemifeneCytochrome P450 2C9enzyme
OspemifeneCytochrome P450 2C19enzyme
OspemifeneCytochrome P450 2B6enzyme
OspemifeneCytochrome P450 2D6enzyme
RomidepsinCytochrome P450 3A4enzyme
RomidepsinCytochrome P450 3A5enzyme
RomidepsinP-glycoprotein 1transporter
RomidepsinSolute carrier organic anion transporter family member 1B3transporter
RomidepsinCytochrome P450 1A1enzyme
RomidepsinCytochrome P450 2B6enzyme
RomidepsinCytochrome P450 2C19enzyme
RomidepsinHistone deacetylase 1target
RomidepsinHistone deacetylase 2target
RomidepsinHistone deacetylase 4target
RomidepsinHistone deacetylase 6target
RomidepsinMultidrug resistance-associated protein 1target
VelpatasvirCytochrome P450 2B6enzyme
VelpatasvirCytochrome P450 2C8enzyme
VelpatasvirCytochrome P450 3A4enzyme
VelpatasvirNonstructural protein 5Atarget
VelpatasvirP-glycoprotein 1transporter
VelpatasvirATP-binding cassette sub-family G member 2transporter
VelpatasvirSolute carrier organic anion transporter family member 1B1transporter
VelpatasvirSolute carrier organic anion transporter family member 1B3transporter
VelpatasvirSolute carrier organic anion transporter family member 2B1transporter
BrivaracetamSynaptic vesicle glycoprotein 2Atarget
BrivaracetamSodium channel proteintarget
BrivaracetamCytochrome P450 3A4enzyme
BrivaracetamCytochrome P450 2C19enzyme
BrivaracetamCytochrome P450 2B6enzyme
BrivaracetamCytochrome P450 2C9enzyme
Testosterone cypionateAndrogen receptortarget
Testosterone cypionateCytochrome P450 3A4enzyme
Testosterone cypionateAmine oxidase [flavin-containing] Aenzyme
Testosterone cypionateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone cypionateSerum albumincarrier
Testosterone cypionateSex hormone-binding globulincarrier
Testosterone cypionateCytochrome P450 3A5enzyme
Testosterone cypionateCytochrome P450 3A7enzyme
Testosterone cypionateSolute carrier organic anion transporter family member 1A2transporter
Testosterone cypionateSolute carrier family 22 member 8transporter
Testosterone cypionateSolute carrier family 22 member 7transporter
Testosterone cypionateP-glycoprotein 1transporter
Testosterone cypionateSodium/bile acid cotransportertransporter
Testosterone cypionateSolute carrier family 22 member 3transporter
Testosterone cypionateSolute carrier family 22 member 4transporter
Testosterone cypionateATP-binding cassette sub-family G member 2transporter
Testosterone cypionateCytochrome P450 1A1enzyme
Testosterone cypionateCytochrome P450 2A13enzyme
Testosterone cypionateCytochrome P450 2B6enzyme
Testosterone cypionateCytochrome P450 2C19enzyme
Testosterone cypionateCytochrome P450 2C8enzyme
Testosterone cypionateCytochrome P450 2C9enzyme
Testosterone cypionateCytochrome P450 3A43enzyme
Testosterone cypionateEstrogen receptor alphatarget
Testosterone cypionateMineralocorticoid receptortarget
Testosterone cypionate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone cypionateCytochrome P450 19A1enzyme
Testosterone enanthateAndrogen receptortarget
Testosterone enanthateCytochrome P450 3A4enzyme
Testosterone enanthateAmine oxidase [flavin-containing] Aenzyme
Testosterone enanthateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone enanthateSerum albumincarrier
Testosterone enanthateSex hormone-binding globulincarrier
Testosterone enanthateCytochrome P450 3A5enzyme
Testosterone enanthateCytochrome P450 3A7enzyme
Testosterone enanthateSolute carrier organic anion transporter family member 1A2transporter
Testosterone enanthateSolute carrier family 22 member 8transporter
Testosterone enanthateSolute carrier family 22 member 7transporter
Testosterone enanthateP-glycoprotein 1transporter
Testosterone enanthateSodium/bile acid cotransportertransporter
Testosterone enanthateSolute carrier family 22 member 3transporter
Testosterone enanthateSolute carrier family 22 member 4transporter
Testosterone enanthateATP-binding cassette sub-family G member 2transporter
Testosterone enanthateCytochrome P450 1A1enzyme
Testosterone enanthateCytochrome P450 2A13enzyme
Testosterone enanthateCytochrome P450 2B6enzyme
Testosterone enanthateCytochrome P450 2C19enzyme
Testosterone enanthateCytochrome P450 2C8enzyme
Testosterone enanthateCytochrome P450 2C9enzyme
Testosterone enanthateCytochrome P450 3A43enzyme
Testosterone enanthateEstrogen receptor alphatarget
Testosterone enanthateMineralocorticoid receptortarget
Testosterone enanthate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone enanthateCytochrome P450 19A1enzyme
Testosterone undecanoateAndrogen receptortarget
Testosterone undecanoateCytochrome P450 3A4enzyme
Testosterone undecanoateAmine oxidase [flavin-containing] Aenzyme
Testosterone undecanoateCholesterol side-chain cleavage enzyme, mitochondrialenzyme
Testosterone undecanoateSerum albumincarrier
Testosterone undecanoateSex hormone-binding globulincarrier
Testosterone undecanoateCytochrome P450 3A5enzyme
Testosterone undecanoateCytochrome P450 3A7enzyme
Testosterone undecanoateSolute carrier organic anion transporter family member 1A2transporter
Testosterone undecanoateSolute carrier family 22 member 8transporter
Testosterone undecanoateSolute carrier family 22 member 7transporter
Testosterone undecanoateP-glycoprotein 1transporter
Testosterone undecanoateSodium/bile acid cotransportertransporter
Testosterone undecanoateSolute carrier family 22 member 4transporter
Testosterone undecanoateATP-binding cassette sub-family G member 2transporter
Testosterone undecanoateCytochrome P450 1A1enzyme
Testosterone undecanoateCytochrome P450 1B1enzyme
Testosterone undecanoateCytochrome P450 2A13enzyme
Testosterone undecanoateCytochrome P450 2B6enzyme
Testosterone undecanoateCytochrome P450 2C19enzyme
Testosterone undecanoateCytochrome P450 2C8enzyme
Testosterone undecanoateCytochrome P450 2C9enzyme
Testosterone undecanoateCytochrome P450 3A43enzyme
Testosterone undecanoateEstrogen receptor alphatarget
Testosterone undecanoateMineralocorticoid receptortarget
Testosterone undecanoate3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
Testosterone undecanoateSolute carrier family 22 member 2transporter
Testosterone undecanoateMultidrug and toxin extrusion protein 1transporter
Testosterone undecanoateSolute carrier organic anion transporter family member 1B3transporter
Testosterone undecanoateCytochrome P450 19A1enzyme
ArtemisininCytochrome P450 2B6enzyme
EsketamineNMDA receptortarget
EsketamineCytochrome P450 2B6enzyme
EsketamineCytochrome P450 3A4enzyme
EsketamineCytochrome P450 2C19enzyme
EsketamineCytochrome P450 2C9enzyme
EsketamineGlutamate receptor ionotropic, NMDA 2Btarget
EsketamineElongation factor 2target
EsketamineBrain-derived neurotrophic factortarget
EsketamineBDNF/NT-3 growth factors receptortarget
HydrocodoneMu-type opioid receptortarget
HydrocodoneDelta-type opioid receptortarget
HydrocodoneCytochrome P450 3A4enzyme
HydrocodoneCytochrome P450 2D6enzyme
HydrocodoneCytochrome P450 2B6enzyme
HydrocodoneCytochrome P450 2C19enzyme
HydrocodoneSigma non-opioid intracellular receptor 1target
AmlodipineCarbonic anhydrase 1target
AmlodipineCytochrome P450 3A4enzyme
AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
AmlodipineCytochrome P450 1A1enzyme
AmlodipineCytochrome P450 2B6enzyme
AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
AmlodipineCytochrome P450 3A5enzyme
AmlodipineP-glycoprotein 1transporter
AmlodipineCytochrome P450 2C8enzyme
AmlodipineCytochrome P450 2D6enzyme
AmlodipineSphingomyelin phosphodiesterasetarget
AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
AmlodipineVoltage-dependent N-type calcium channeltarget
DiazepamCytochrome P450 3A4enzyme
DiazepamSerum albumincarrier
DiazepamCytochrome P450 2C9enzyme
DiazepamCytochrome P450 2C19enzyme
DiazepamCytochrome P450 3A5enzyme
DiazepamCytochrome P450 3A7enzyme
DiazepamP-glycoprotein 1transporter
DiazepamCytochrome P450 2B6enzyme
DiazepamProstaglandin G/H synthase 1enzyme
DiazepamCytochrome P450 2C18enzyme
DiazepamCytochrome P450 2C8enzyme
DiazepamCytochrome P450 2E1enzyme
DiazepamGABA(A) Receptortarget
DiazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DexloxiglumideCholecystokinin receptor type Atarget
DexloxiglumideCytochrome P450 3A4enzyme
DexloxiglumideCytochrome P450 2C9enzyme
DexloxiglumideCytochrome P450 3A5enzyme
DexloxiglumideCytochrome P450 2B6enzyme
DexloxiglumideCytochrome P450 2E1enzyme
MetoprololBeta-1 adrenergic receptortarget
MetoprololCytochrome P450 2D6enzyme
MetoprololBeta-2 adrenergic receptortarget
MetoprololSolute carrier family 22 member 2transporter
MetoprololSerum albumincarrier
MetoprololCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent serotonin transportertarget
VenlafaxineSodium-dependent noradrenaline transportertarget
VenlafaxineCytochrome P450 2D6enzyme
VenlafaxineCytochrome P450 3A4enzyme
VenlafaxineSodium-dependent dopamine transportertarget
VenlafaxineP-glycoprotein 1transporter
VenlafaxineATP-binding cassette sub-family G member 2transporter
AtomoxetineSodium-dependent noradrenaline transportertarget
AtomoxetineCytochrome P450 2D6enzyme
AtomoxetineSodium-dependent serotonin transportertarget
AtomoxetineCytochrome P450 2C19enzyme
AtomoxetineNMDA receptortarget
AtomoxetineSerum albumincarrier
Atomoxetinealpha1-acid glycoproteincarrier
AtomoxetineHigh affinity immunoglobulin gamma Fc receptor Icarrier
AtomoxetineG protein-activated inward rectifier potassium channel 1target
AtomoxetineKappa-type opioid receptortarget
CodeineMu-type opioid receptortarget
CodeineDelta-type opioid receptortarget
CodeineKappa-type opioid receptortarget
CodeineCytochrome P450 2D6enzyme
CodeineCytochrome P450 3A4enzyme
CodeineSolute carrier family 22 member 1transporter
CodeineUDP-glucuronosyltransferase 2B7enzyme
CodeineUDP-glucuronosyltransferase 2B4enzyme
TimololBeta-1 adrenergic receptortarget
TimololBeta-2 adrenergic receptortarget
TimololCytochrome P450 2D6enzyme
TimololP-glycoprotein 1transporter
TimololCytochrome P450 2C19enzyme
TimololLysozymetarget
OxycodoneMu-type opioid receptortarget
OxycodoneKappa-type opioid receptortarget
OxycodoneDelta-type opioid receptortarget
OxycodoneCytochrome P450 2D6enzyme
OxycodoneCytochrome P450 3A4enzyme
OxycodoneCytochrome P450 3A5enzyme
OxycodoneSerum albumincarrier
Oxycodonealpha1-acid glycoproteincarrier
ThioridazineAlpha-1A adrenergic receptortarget
ThioridazineDopamine D2 receptortarget
Thioridazine5-hydroxytryptamine receptor 2Atarget
ThioridazineDopamine D1 receptortarget
ThioridazineCytochrome P450 2C19enzyme
ThioridazineCytochrome P450 2D6enzyme
ThioridazineAlpha-1B adrenergic receptortarget
ThioridazinePotassium voltage-gated channel subfamily H member 2target
ThioridazineCytochrome P450 2E1enzyme
RisperidoneCytochrome P450 2D6enzyme
RisperidoneCytochrome P450 3A4enzyme
RisperidoneP-glycoprotein 1transporter
RisperidoneSerum albumincarrier
RisperidoneAlpha-1-acid glycoprotein 1carrier
Risperidone5-hydroxytryptamine receptor 2Atarget
RisperidoneDopamine D2 receptortarget
RisperidoneAlpha-1B adrenergic receptortarget
RisperidoneAlpha-2B adrenergic receptortarget
RisperidoneAlpha-1A adrenergic receptortarget
RisperidoneAlpha-2C adrenergic receptortarget
RisperidoneHistamine H1 receptortarget
Risperidone5-hydroxytryptamine receptor 2Ctarget
Risperidone5-hydroxytryptamine receptor 1Dtarget
Risperidone5-hydroxytryptamine receptor 1Atarget
Risperidone5-hydroxytryptamine receptor 7target
RisperidoneD(2L) dopamine receptortarget
RisperidoneDopamine D1 receptortarget
FlecainideSodium channel protein type 5 subunit alphatarget
FlecainideCytochrome P450 2D6enzyme
FlecainideSodium channel protein type 4 subunit alphatarget
FlecainideCytochrome P450 2C9enzyme
FlecainidePotassium voltage-gated channel subfamily H member 2target
Flecainidealpha1-acid glycoproteincarrier
FlecainideSerum albumincarrier
FlecainideCytochrome P450 1A2enzyme
FlecainideP-glycoprotein 1transporter
FlecainideMultidrug and toxin extrusion protein 1transporter
FlecainideRyanodine receptor 2target
AripiprazoleDopamine D2 receptortarget
Aripiprazole5-hydroxytryptamine receptor 1Atarget
Aripiprazole5-hydroxytryptamine receptor 2Atarget
AripiprazoleCytochrome P450 3A4enzyme
AripiprazoleCytochrome P450 2D6enzyme
Aripiprazole5-hydroxytryptamine receptor 1Btarget
Aripiprazole5-hydroxytryptamine receptor 1Dtarget
Aripiprazole5-hydroxytryptamine receptor 1Etarget
AripiprazoleDopamine D1 receptortarget
AripiprazoleDopamine D5 receptortarget
AripiprazoleDopamine D3 receptortarget
AripiprazoleDopamine D4 receptortarget
Aripiprazole5-hydroxytryptamine receptor 2Ctarget
Aripiprazole5-hydroxytryptamine receptor 3Atarget
Aripiprazole5-hydroxytryptamine receptor 6target
Aripiprazole5-hydroxytryptamine receptor 7target
AripiprazoleHistamine H1 receptortarget
AripiprazoleAlpha-1A adrenergic receptortarget
AripiprazoleAlpha-1B adrenergic receptortarget
AripiprazoleAlpha-2A adrenergic receptortarget
AripiprazoleAlpha-2B adrenergic receptortarget
AripiprazoleAlpha-2C adrenergic receptortarget
AripiprazoleCytochrome P450 3A5enzyme
AripiprazoleCytochrome P450 3A7enzyme
AripiprazoleSerum albumincarrier
Aripiprazole5-hydroxytryptamine receptor 2Btarget
Aripiprazole5-hydroxytryptamine receptor 5Atarget
AripiprazoleBeta-1 adrenergic receptortarget
AripiprazoleBeta-2 adrenergic receptortarget
AripiprazoleHistamine H2 receptortarget
AripiprazoleHistamine H3 receptortarget
AripiprazoleHistamine H4 receptortarget
AripiprazoleMuscarinic acetylcholine receptor M1target
AripiprazoleMuscarinic acetylcholine receptor M2target
AripiprazoleMuscarinic acetylcholine receptor M3target
AripiprazoleMuscarinic acetylcholine receptor M4target
AripiprazoleMuscarinic acetylcholine receptor M5target
AripiprazoleKappa-type opioid receptortarget
AripiprazoleMu-type opioid receptortarget
AripiprazoleDelta-type opioid receptortarget
AripiprazoleGlutamate (NMDA) receptortarget
AripiprazoleSodium-dependent dopamine transportertarget
AripiprazoleSodium-dependent serotonin transportertarget
TafenoquineCytochrome P450 2D6enzyme
TafenoquineFerredoxin--NADP reductase, apicoplastenzyme
TafenoquineSolute carrier family 22 member 2transporter
TafenoquineMultidrug and toxin extrusion protein 1transporter
TafenoquineMultidrug and toxin extrusion protein 2transporter
ProtriptylineSodium-dependent noradrenaline transportertarget
ProtriptylineSodium-dependent serotonin transportertarget
ProtriptylineP-glycoprotein 1transporter
ProgesteroneProgesterone receptortarget
ProgesteroneEstrogen receptor alphatarget
ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
ProgesteroneCytochrome P450 2C19enzyme
ProgesteroneCytochrome P450 2C9enzyme
ProgesteroneCytochrome P450 3A4enzyme
ProgesteroneCytochrome P450 3A5enzyme
ProgesteroneCytochrome P450 3A7enzyme
ProgesteroneP-glycoprotein 1transporter
ProgesteroneSolute carrier family 22 member 2transporter
ProgesteroneSolute carrier family 22 member 1transporter
ProgesteroneSolute carrier family 22 member 3transporter
ProgesteroneBile salt export pumptransporter
ProgesteroneMultidrug resistance-associated protein 1transporter
ProgesteroneSodium/bile acid cotransportertransporter
ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
ProgesteroneCytochrome P450 1A1enzyme
ProgesteroneCytochrome P450 1B1enzyme
ProgesteroneCytochrome P450 2A6enzyme
ProgesteroneCytochrome P450 2D6enzyme
ProgesteroneMineralocorticoid receptortarget
ProgesteroneKappa-type opioid receptortarget
ProgesteroneAlpha-1-acid glycoprotein 1target
ProgesteroneGlucocorticoid receptortarget
ProgesteroneAndrogen receptortarget
ProgesteroneSex hormone-binding globulintarget
ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
ProgesteroneATP-binding cassette sub-family G member 2transporter
ProgesteroneEstrogen receptor betatarget
ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
ElagolixGonadotropin-releasing hormone receptortarget
ElagolixCytochrome P450 3A Subfamilyenzyme
ElagolixCytochrome P450 2D6enzyme
ElagolixCytochrome P450 2C8enzyme
ElagolixP-glycoprotein 1transporter
ElagolixSolute carrier organic anion transporter family member 1B1transporter
AcebutololBeta-1 adrenergic receptortarget
AcebutololCytochrome P450 2D6enzyme
AcebutololBeta-2 adrenergic receptortarget
AcebutololP-glycoprotein 1transporter
AlprenololBeta-1 adrenergic receptortarget
AlprenololBeta-2 adrenergic receptortarget
Alprenolol5-hydroxytryptamine receptor 1Atarget
AlprenololCytochrome P450 2D6enzyme
AlprenololBeta-3 adrenergic receptortarget
AnisodamineCytochrome P450 2D6enzyme
ArotinololBeta-1 adrenergic receptortarget
ArotinololBeta-2 adrenergic receptortarget
ArotinololAlpha-1 adrenergic receptorstarget
ArotinololSerum albumincarrier
ArotinololAlpha-1-acid glycoprotein 1carrier
ArotinololCytochrome P450 2D6enzyme
AtenololBeta-1 adrenergic receptortarget
AtenololBeta-2 adrenergic receptortarget
AtenololCytochrome P450 2D6enzyme
AtenololBile salt export pumptransporter
AtenololSerum albumincarrier
BefunololBeta-1 adrenergic receptortarget
BefunololBeta-2 adrenergic receptortarget
BefunololCytochrome P450 2D6enzyme
BevantololBeta-1 adrenergic receptortarget
BevantololBeta-2 adrenergic receptortarget
BevantololAlpha-1A adrenergic receptortarget
BevantololCytochrome P450 2D6enzyme
BopindololBeta-1 adrenergic receptortarget
BopindololBeta-2 adrenergic receptortarget
Bopindolol5-hydroxytryptamine receptor 1Atarget
Bopindolol5-hydroxytryptamine receptor 1Btarget
BopindololBeta-3 adrenergic receptortarget
BopindololCytochrome P450 2D6enzyme
BucindololCytochrome P450 2D6enzyme
BufuralolCytochrome P450 2D6enzyme
BufuralolBeta adrenergic receptortarget
BupranololBeta-1 adrenergic receptortarget
BupranololBeta-2 adrenergic receptortarget
BupranololBeta-3 adrenergic receptortarget
BupranololCytochrome P450 2D6enzyme
CarteololBeta-2 adrenergic receptortarget
CarteololBeta-1 adrenergic receptortarget
CarteololCytochrome P450 2D6enzyme
CeliprololBeta-1 adrenergic receptortarget
CeliprololBeta-2 adrenergic receptortarget
CeliprololBeta-3 adrenergic receptortarget
CeliprololAlpha-2A adrenergic receptortarget
CeliprololAlpha-2B adrenergic receptortarget
CeliprololAlpha-2C adrenergic receptortarget
CeliprololCytochrome P450 2D6enzyme
CloranololCytochrome P450 2D6enzyme
EpanololCytochrome P450 2D6enzyme
EsatenololCytochrome P450 2D6enzyme
EsmololBeta-1 adrenergic receptortarget
EsmololCytochrome P450 2D6enzyme
IndenololCytochrome P450 2D6enzyme
LandiololCytochrome P450 2D6enzyme
LevobetaxololBeta-1 adrenergic receptortarget
LevobetaxololCytochrome P450 2D6enzyme
LevobunololBeta-1 adrenergic receptortarget
LevobunololBeta-2 adrenergic receptortarget
LevobunololCytochrome P450 2D6enzyme
MepindololCytochrome P450 2D6enzyme
MetipranololBeta-1 adrenergic receptortarget
MetipranololBeta-2 adrenergic receptortarget
MetipranololCytochrome P450 2D6enzyme
NadololBeta-1 adrenergic receptortarget
NadololBeta-2 adrenergic receptortarget
NadololP-glycoprotein 1transporter
NadololPOU domain, class 2, transcription factor 1transporter
NadololPOU domain, class 2, transcription factor 2transporter
NadololMultidrug and toxin extrusion protein 1transporter
NadololMultidrug and toxin extrusion protein 2transporter
Nadololalpha1-acid glycoproteincarrier
NebivololBeta-1 adrenergic receptortarget
NebivololCytochrome P450 2D6enzyme
NebivololBeta-2 adrenergic receptortarget
NebivololCytochrome P450 3A4enzyme
NebivololSerum albumincarrier
NebivololBeta-3 adrenergic receptortarget
NebivololCytochrome P450 2C19enzyme
OxprenololBeta-1 adrenergic receptortarget
OxprenololBeta-2 adrenergic receptortarget
OxprenololSolute carrier family 22 member 2transporter
OxprenololCytochrome P450 2D6enzyme
OxprenololBeta-3 adrenergic receptortarget
PenbutololAlpha-1-acid glycoprotein 1carrier
PenbutololBeta-1 adrenergic receptortarget
PenbutololBeta-2 adrenergic receptortarget
Penbutolol5-hydroxytryptamine receptor 1Atarget
Penbutolol5-hydroxytryptamine receptor 1Btarget
PenbutololCytochrome P450 2D6enzyme
PindololBeta-1 adrenergic receptortarget
PindololBeta-2 adrenergic receptortarget
Pindolol5-hydroxytryptamine receptor 1Atarget
Pindolol5-hydroxytryptamine receptor 1Btarget
PindololCytochrome P450 2D6enzyme
PindololBeta-3 adrenergic receptortarget
PractololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
SotalolPotassium voltage-gated channel subfamily H member 2target
SotalolBeta-1 adrenergic receptortarget
SotalolBeta-2 adrenergic receptortarget
SotalolCytochrome P450 2D6enzyme
TalinololCytochrome P450 2D6enzyme
TalinololP-glycoprotein 1transporter
TalinololCanalicular multispecific organic anion transporter 1transporter
TertatololCytochrome P450 2D6enzyme
PaliperidoneDopamine D2 receptortarget
Paliperidone5-hydroxytryptamine receptor 2Atarget
PaliperidoneHistamine H1 receptortarget
PaliperidoneAlpha-1A adrenergic receptortarget
PaliperidoneAlpha-1B adrenergic receptortarget
PaliperidoneDopamine D3 receptortarget
PaliperidoneDopamine D4 receptortarget
PaliperidoneDopamine D1 receptortarget
PaliperidoneAlpha-2A adrenergic receptortarget
PaliperidoneAlpha-2B adrenergic receptortarget
PaliperidoneAlpha-2C adrenergic receptortarget
Paliperidone5-hydroxytryptamine receptor 1Atarget
Paliperidone5-hydroxytryptamine receptor 1Dtarget
Paliperidone5-hydroxytryptamine receptor 2Ctarget
Paliperidone5-hydroxytryptamine receptor 7target
PaliperidoneCytochrome P450 3A4enzyme
PaliperidoneCytochrome P450 2D6enzyme
PaliperidoneCytochrome P450 3A5enzyme
PaliperidoneP-glycoprotein 1transporter
Dapoxetine5-hydroxytryptamine receptor 1Atarget
Dapoxetine5-hydroxytryptamine receptor 1Btarget
Dapoxetine5-hydroxytryptamine receptor 2Ctarget
DapoxetineCytochrome P450 3A4enzyme
DapoxetineCytochrome P450 2D6enzyme
CitalopramSodium-dependent serotonin transportertarget
CitalopramCytochrome P450 2C19enzyme
CitalopramCytochrome P450 2D6enzyme
CitalopramCytochrome P450 3A4enzyme
CitalopramP-glycoprotein 1transporter
CitalopramCytochrome P450 1A2enzyme
CitalopramHistamine H1 receptortarget
EscitalopramSodium-dependent serotonin transportertarget
EscitalopramCytochrome P450 3A4enzyme
EscitalopramCytochrome P450 2D6enzyme
EscitalopramSodium-dependent dopamine transportertarget
EscitalopramSodium-dependent noradrenaline transportertarget
EscitalopramMuscarinic acetylcholine receptor M1target
EscitalopramHistamine H1 receptortarget
EscitalopramCytochrome P450 2C19enzyme
EscitalopramMonoamine oxidaseenzyme
EscitalopramP-glycoprotein 1transporter
Escitalopram5-hydroxytryptamine receptor 1Atarget
Escitalopram5-hydroxytryptamine receptor 2Atarget
Escitalopram5-hydroxytryptamine receptor 2Ctarget
EscitalopramAlpha-1 adrenergic receptorstarget
EscitalopramAlpha-2 adrenergic receptorstarget
EscitalopramDopamine D2 receptortarget
LevomilnacipranCytochrome P450 3A4enzyme
LevomilnacipranCytochrome P450 2C8enzyme
LevomilnacipranCytochrome P450 2C19enzyme
LevomilnacipranCytochrome P450 2D6enzyme
LevomilnacipranCytochrome P450 2J2enzyme
LevomilnacipranSodium-dependent serotonin transportertarget
LevomilnacipranSodium-dependent noradrenaline transportertarget
LevomilnacipranP-glycoprotein 1transporter
Nefazodone5-hydroxytryptamine receptor 2Atarget
NefazodoneSodium-dependent serotonin transportertarget
NefazodoneSodium-dependent noradrenaline transportertarget
NefazodoneAlpha-1A adrenergic receptortarget
NefazodoneAlpha-1B adrenergic receptortarget
NefazodoneCytochrome P450 3A4enzyme
NefazodoneCytochrome P450 2D6enzyme
NefazodoneSodium-dependent dopamine transportertarget
NefazodoneAlpha-2A adrenergic receptortarget
Nefazodone5-hydroxytryptamine receptor 1Atarget
NefazodoneCYP2B proteinenzyme
NefazodoneP-glycoprotein 1transporter
Nefazodone5-hydroxytryptamine receptor 2Ctarget
NefazodonePotassium voltage-gated channel subfamily H member 2target
NefazodoneCytochrome P450 3A Subfamilyenzyme
NefazodoneSolute carrier organic anion transporter family member 1B3transporter
NefazodoneSolute carrier organic anion transporter family member 2B1transporter
NefazodoneBile salt export pumptransporter
Trazodone5-hydroxytryptamine receptor 2Atarget
TrazodoneSodium-dependent serotonin transportertarget
TrazodoneAlpha-1A adrenergic receptortarget
TrazodoneAlpha-2A adrenergic receptortarget
TrazodoneHistamine H1 receptortarget
Trazodone5-hydroxytryptamine receptor 1Atarget
TrazodoneCytochrome P450 2D6enzyme
TrazodoneCytochrome P450 3A4enzyme
Trazodone5-hydroxytryptamine receptor 2Ctarget
TrazodoneCytochrome P450 3A5enzyme
TrazodoneCytochrome P450 3A7enzyme
TrazodoneP-glycoprotein 1transporter
Trazodone5-hydroxytryptamine receptor 1Ctarget
Fusidic acidChloramphenicol acetyltransferase 3target
Fusidic acidChloramphenicol acetyltransferasetarget
Fusidic acidBile salt export pumptransporter
Fusidic acidCanalicular multispecific organic anion transporter 1transporter
Fusidic acidElongation factor Gtarget
Fusidic acidCytochrome P450 2D6enzyme
Fusidic acidCytochrome P450 3A4enzyme
Fusidic acidUDP-glucuronosyltransferase 1-1enzyme
Fusidic acidATP-binding cassette sub-family G member 2transporter
Fusidic acidSolute carrier organic anion transporter family member 1B1transporter
GalantamineAcetylcholinesterasetarget
GalantamineCytochrome P450 3A4enzyme
GalantamineCytochrome P450 2D6enzyme
GalantamineCholinesterasetarget
GalantamineP-glycoprotein 1transporter
GalantamineNeuronal acetylcholine receptor subunit alpha-7target
GalantamineMuscle nicotinic acetylcholine receptortarget
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
BuprenorphineKappa-type opioid receptortarget
BuprenorphineMu-type opioid receptortarget
BuprenorphineCytochrome P450 3A4enzyme
BuprenorphineCytochrome P450 2D6enzyme
BuprenorphineP-glycoprotein 1transporter
BuprenorphineATP-binding cassette sub-family G member 2transporter
BuprenorphineCytochrome P450 2C9enzyme
BuprenorphineCytochrome P450 3A5enzyme
BuprenorphineCytochrome P450 2C8enzyme
BuprenorphineCytochrome P450 3A7enzyme
BuprenorphineDelta-type opioid receptortarget
BuprenorphineCytochrome P450 2C18enzyme
BuprenorphineCytochrome P450 2C19enzyme
BuprenorphineNociceptin receptortarget
Buspirone5-hydroxytryptamine receptor 1Atarget
BuspironeDopamine D2 receptortarget
BuspironeCytochrome P450 3A4enzyme
BuspironeCytochrome P450 3A5enzyme
BuspironeCytochrome P450 3A7enzyme
BuspironeP-glycoprotein 1transporter
BuspironeCytochrome P450 2D6enzyme
BuspironeSerum albumincarrier
BuspironeAlpha-1-acid glycoprotein 1carrier
BuspironeDopamine D3 receptortarget
BuspironeDopamine D4 receptortarget
BuspironeAlpha-1 adrenergic receptorstarget
BepridilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
BepridilSodium/potassium-transporting ATPase subunit alpha-1target
BepridilPotassium voltage-gated channel subfamily KQT member 1target
BepridilTroponin C, slow skeletal and cardiac musclestarget
BepridilCalmodulintarget
BepridilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
BepridilVoltage-dependent calcium channel subunit alpha-2/delta-2target
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
BepridilCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
BepridilP-glycoprotein 1transporter
BepridilCytochrome P450 2D6enzyme
BepridilPotassium voltage-gated channel subfamily H member 2target
BepridilCytochrome P450 3A4enzyme
Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
FluvastatinCytochrome P450 2C9enzyme
FluvastatinCytochrome P450 3A4enzyme
FluvastatinCytochrome P450 2C8enzyme
FluvastatinCytochrome P450 2D6enzyme
FluvastatinCytochrome P450 2C19enzyme
FluvastatinCytochrome P450 1A1enzyme
FluvastatinSolute carrier organic anion transporter family member 1B1transporter
FluvastatinSolute carrier organic anion transporter family member 1B3transporter
FluvastatinSolute carrier organic anion transporter family member 2B1transporter
FluvastatinSolute carrier family 15 member 1transporter
FluvastatinCytochrome P450 3A5enzyme
FluvastatinUDP-glucuronosyltransferase 1-1enzyme
FluvastatinUDP-glucuronosyltransferase 1-3enzyme
FluvastatinUDP-glucuronosyltransferase 2B7enzyme
FluvastatinCanalicular multispecific organic anion transporter 1transporter
FluvastatinCytochrome P450 2B6enzyme
FluvastatinHistone deacetylase 2target
Aripiprazole lauroxilDopamine D2 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Atarget
Aripiprazole lauroxilCytochrome P450 3A4enzyme
Aripiprazole lauroxilCytochrome P450 2D6enzyme
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Btarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Dtarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 1Etarget
Aripiprazole lauroxilDopamine D1 receptortarget
Aripiprazole lauroxilDopamine D5 receptortarget
Aripiprazole lauroxilDopamine D3 receptortarget
Aripiprazole lauroxilDopamine D4 receptortarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 2Ctarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 3Atarget
Aripiprazole lauroxil5-hydroxytryptamine receptor 6target
Aripiprazole lauroxil5-hydroxytryptamine receptor 7target
Aripiprazole lauroxilHistamine H1 receptortarget
Aripiprazole lauroxilAlpha-1A adrenergic receptortarget
Aripiprazole lauroxilAlpha-1B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2A adrenergic receptortarget
Aripiprazole lauroxilAlpha-2B adrenergic receptortarget
Aripiprazole lauroxilAlpha-2C adrenergic receptortarget
Aripiprazole lauroxilMuscarinic acetylcholine receptor M1target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M2target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M3target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M4target
Aripiprazole lauroxilMuscarinic acetylcholine receptor M5target
Aripiprazole lauroxilCytochrome P450 3A5enzyme
Aripiprazole lauroxilCytochrome P450 3A7enzyme
Aripiprazole lauroxilSerum albumincarrier
ZuclopenthixolDopamine D1 receptortarget
ZuclopenthixolDopamine D5 receptortarget
ZuclopenthixolDopamine D2 receptortarget
ZuclopenthixolCytochrome P450 2D6enzyme
ZuclopenthixolAlpha-1A adrenergic receptortarget
ZuclopenthixolAlpha-2A adrenergic receptortarget
Zuclopenthixol5-hydroxytryptamine receptor 2Atarget
ZuclopenthixolHistamine H1 receptortarget
ZuclopenthixolCytochrome P450 3A4enzyme
FesoterodineMuscarinic acetylcholine receptor M1target
FesoterodineMuscarinic acetylcholine receptor M3target
FesoterodineCytochrome P450 3A4enzyme
FesoterodineMuscarinic acetylcholine receptor M2target
FesoterodineMuscarinic acetylcholine receptor M4target
FesoterodineMuscarinic acetylcholine receptor M5target
FesoterodineCytochrome P450 2D6enzyme
FesoterodineP-glycoprotein 1transporter
PitolisantHistamine H3 receptortarget
PitolisantCytochrome P450 3A4enzyme
PitolisantCytochrome P450 2D6enzyme
PitolisantCytochrome P450 1A2enzyme
PitolisantCytochrome P450 2B6enzyme
PitolisantSolute carrier family 22 member 1transporter
PitolisantPotassium voltage-gated channel subfamily H member 2target
PitolisantSerum albumincarrier
PitolisantAlpha-1-acid glycoprotein 1carrier
BrexpiprazoleCytochrome P450 2D6enzyme
BrexpiprazoleCytochrome P450 3A4enzyme
Brexpiprazole5-hydroxytryptamine receptor 1Atarget
BrexpiprazoleDopamine D2 receptortarget
Brexpiprazole5-hydroxytryptamine receptor 2Atarget
BrexpiprazoleAlpha-2C adrenergic receptortarget
BrexpiprazoleAlpha-1B adrenergic receptortarget
EliglustatCeramide glucosyltransferasetarget
EliglustatCytochrome P450 2D6enzyme
EliglustatCytochrome P450 3A4enzyme
EliglustatP-glycoprotein 1transporter
AmphetamineSodium-dependent dopamine transportertarget
AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
AmphetamineTrace amine-associated receptor 1target
AmphetamineCytochrome P450 2D6enzyme
AmphetamineSolute carrier family 22 member 3transporter
AmphetamineSolute carrier family 22 member 5transporter
AmphetamineSynaptic vesicular amine transportertarget
AmphetamineCytochrome P450 2A6enzyme
AmphetamineSodium-dependent noradrenaline transportertarget
AmphetamineAlpha adrenergic receptortarget
AmphetamineBeta adrenergic receptortarget
AmphetamineDopamine D2 receptortarget
AmphetamineAmine oxidase [flavin-containing] Btarget
AmphetamineSodium-dependent serotonin transportertarget
AmphetamineMonoamine oxidasetarget
Amphetaminevesicular monoamine transporter 2 (VMAT2)target
CevimelineMuscarinic acetylcholine receptor M1target
CevimelineMuscarinic acetylcholine receptor M3target
CevimelineCytochrome P450 3A4enzyme
CevimelineCytochrome P450 2D6enzyme
CevimelineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
ProchlorperazineDopamine D2 receptortarget
ProchlorperazineCytochrome P450 2D6enzyme
ProchlorperazineHistamine H1 receptortarget
ProchlorperazineAlpha-1 adrenergic receptorstarget
ProchlorperazineAlpha-2 adrenergic receptorstarget
DarifenacinMuscarinic acetylcholine receptor M3target
DarifenacinCytochrome P450 3A4enzyme
DarifenacinCytochrome P450 2D6enzyme
DarifenacinMuscarinic acetylcholine receptor M1target
DarifenacinMuscarinic acetylcholine receptor M2target
DarifenacinMuscarinic acetylcholine receptor M4target
DarifenacinMuscarinic acetylcholine receptor M5target
NicergolineAlpha-1A adrenergic receptortarget
NicergolineCytochrome P450 2D6enzyme
Dolasetron5-hydroxytryptamine receptor 3Atarget
DolasetronCytochrome P450 3A4enzyme
DolasetronCytochrome P450 2D6enzyme
DolasetronCytochrome P450 2C9enzyme
MinaprineDopamine D1 receptortarget
MinaprineDopamine D2 receptortarget
Minaprine5-hydroxytryptamine receptor 2Atarget
Minaprine5-hydroxytryptamine receptor 2Btarget
Minaprine5-hydroxytryptamine receptor 2Ctarget
MinaprineSodium-dependent serotonin transportertarget
MinaprineCytochrome P450 2D6enzyme
MinaprineMuscarinic acetylcholine receptor M1target
MinaprineAcetylcholinesterasetarget
MinaprineAmine oxidase [flavin-containing] Atarget
DonepezilAcetylcholinesterasetarget
Donepezil5-hydroxytryptamine receptor 2Atarget
DonepezilCytochrome P450 3A4enzyme
DonepezilCytochrome P450 2D6enzyme
DonepezilCytochrome P450 2C9enzyme
DonepezilCholinesterasetarget
DonepezilNitric oxide synthase, braintarget
DonepezilTumor necrosis factor-inducible gene 6 proteintarget
DonepezilInterleukin-1 betatarget
DonepezilNuclear factor NF-kappa-Btarget
DonepezilATP-binding cassette sub-family G member 2transporter
DonepezilNMDA receptortarget
Phenformin5'-AMP-activated protein kinase catalytic subunit alpha-1target
PhenforminCytochrome P450 2D6enzyme
PhenforminSolute carrier family 22 member 2transporter
PhenforminSolute carrier family 22 member 1transporter
PhenforminATP-sensitive inward rectifier potassium channel 8target
Almotriptan5-hydroxytryptamine receptor 1Dtarget
Almotriptan5-hydroxytryptamine receptor 1Btarget
AlmotriptanCytochrome P450 3A4enzyme
AlmotriptanCytochrome P450 2D6enzyme
AlmotriptanAmine oxidase [flavin-containing] Aenzyme
AlmotriptanDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
AlmotriptanCytochrome P450 2C19enzyme
AlmotriptanCytochrome P450 2E1enzyme
AlmotriptanCytochrome P450 2C8enzyme
ProcainamideSodium channel protein type 5 subunit alphatarget
ProcainamideDNA (cytosine-5)-methyltransferase 1target
ProcainamideCytochrome P450 2D6enzyme
ProcainamideCholinesteraseenzyme
ProcainamideSolute carrier family 22 member 2transporter
ProcainamideSolute carrier family 22 member 1transporter
ProcainamideSolute carrier family 22 member 3transporter
ProcainamideSolute carrier family 22 member 5transporter
ProcainamideSolute carrier family 22 member 4transporter
ProcainamidePotassium voltage-gated channel subfamily H member 2target
ProcainamideMultidrug and toxin extrusion protein 1transporter
ProcainamideMultidrug and toxin extrusion protein 2transporter
TolterodineMuscarinic acetylcholine receptor M1target
TolterodineMuscarinic acetylcholine receptor M2target
TolterodineMuscarinic acetylcholine receptor M3target
TolterodineCytochrome P450 2D6enzyme
TolterodineCytochrome P450 3A4enzyme
TolterodineCytochrome P450 2C9enzyme
TolterodineCytochrome P450 2C19enzyme
TolterodineMuscarinic acetylcholine receptor M4target
TolterodineMuscarinic acetylcholine receptor M5target
ChlorpheniramineHistamine H1 receptortarget
ChlorpheniramineCytochrome P450 3A4enzyme
ChlorpheniramineCytochrome P450 2D6enzyme
ChlorpheniramineSodium-dependent serotonin transportertarget
ChlorpheniramineSodium-dependent noradrenaline transportertarget
ChlorpheniramineSodium-dependent dopamine transportertarget
ChlorpheniramineCytochrome P450 3A5enzyme
ChlorpheniramineCytochrome P450 3A7enzyme
ChlorpheniramineSolute carrier family 22 member 2transporter
ChlorpheniramineSolute carrier family 22 member 1transporter
EncainideSodium channel protein type 5 subunit alphatarget
EncainideCytochrome P450 2D6enzyme
MoclobemideAmine oxidase [flavin-containing] Atarget
MoclobemideCytochrome P450 2C19enzyme
MoclobemideCytochrome P450 2D6enzyme
MoclobemideAmine oxidase [flavin-containing] Aenzyme
MoclobemideAmine oxidase [flavin-containing] Benzyme
MoclobemideCytochrome P450 2C9enzyme
MoclobemideMonoamine oxidasetarget
MoclobemideAmine oxidase [flavin-containing] Btarget
TiotropiumMuscarinic acetylcholine receptor M3target
TiotropiumCytochrome P450 2D6enzyme
TiotropiumCytochrome P450 3A4enzyme
TiotropiumMuscarinic acetylcholine receptor M1target
TiotropiumMuscarinic acetylcholine receptor M2target
TiotropiumSolute carrier family 22 member 5transporter
TiotropiumSolute carrier family 22 member 4transporter
TiotropiumMuscarinic acetylcholine receptor M4target
TiotropiumMuscarinic acetylcholine receptor M5target
DiphenhydramineHistamine H1 receptortarget
DiphenhydramineCytochrome P450 2D6enzyme
DiphenhydramineCytochrome P450 2C9enzyme
DiphenhydramineCytochrome P450 2C19enzyme
DiphenhydramineSolute carrier family 22 member 2transporter
DiphenhydramineSolute carrier family 22 member 5transporter
DiphenhydramineProstaglandin G/H synthase 1enzyme
DiphenhydramineMuscarinic acetylcholine receptor M2target
DebrisoquineSodium-dependent noradrenaline transportertarget
DebrisoquineCytochrome P450 2D6enzyme
DebrisoquineP-glycoprotein 1transporter
DebrisoquineCytochrome P450 1A1enzyme
GefitinibEpidermal growth factor receptortarget
GefitinibCytochrome P450 3A4enzyme
GefitinibCytochrome P450 2D6enzyme
GefitinibP-glycoprotein 1transporter
GefitinibATP-binding cassette sub-family G member 2transporter
GefitinibCytochrome P450 3A5enzyme
GefitinibCytochrome P450 1A1enzyme
GefitinibCytochrome P450 2C9enzyme
GefitinibCytochrome P450 2C19enzyme
GefitinibSerum albumincarrier
GefitinibAlpha-1-acid glycoprotein 1carrier
TerfenadineHistamine H1 receptortarget
TerfenadinePotassium voltage-gated channel subfamily H member 2target
TerfenadineCytochrome P450 3A4enzyme
TerfenadineCytochrome P450 2D6enzyme
TerfenadineMuscarinic acetylcholine receptor M3target
TerfenadineCytochrome P450 3A5enzyme
TerfenadineCytochrome P450 3A7enzyme
TerfenadineP-glycoprotein 1transporter
TerfenadineCytochrome P450 2C8enzyme
TerfenadineCytochrome P450 2J2enzyme
TerfenadineMuscarinic acetylcholine receptor M1target
TerfenadineMuscarinic acetylcholine receptor M5target
TerfenadineMuscarinic acetylcholine receptor M4target
TerfenadineMuscarinic acetylcholine receptor M2target
TerfenadineBile salt export pumptransporter
DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DiltiazemCytochrome P450 3A4enzyme
DiltiazemCytochrome P450 2C19enzyme
DiltiazemCytochrome P450 2D6enzyme
DiltiazemCytochrome P450 3A5enzyme
DiltiazemCytochrome P450 3A7enzyme
DiltiazemP-glycoprotein 1transporter
DiltiazemCytochrome P450 2C8enzyme
DiltiazemSerum albumincarrier
DiltiazemAlpha-1-acid glycoprotein 1carrier
DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
MesoridazineDopamine D2 receptortarget
Mesoridazine5-hydroxytryptamine receptor 2Atarget
MesoridazineCytochrome P450 2D6enzyme
MequitazineHistamine H1 receptortarget
MequitazineCytochrome P450 2D6enzyme
MequitazineCytochrome P450 3A4enzyme
OxymorphoneMu-type opioid receptortarget
OxymorphoneCytochrome P450 2D6enzyme
OxymorphoneDelta-type opioid receptortarget
OxymorphoneCytochrome P450 3A4enzyme
MethotrimeprazineDopamine D3 receptortarget
MethotrimeprazineHistamine H1 receptortarget
MethotrimeprazineMuscarinic acetylcholine receptor M1target
MethotrimeprazineMuscarinic acetylcholine receptor M2target
MethotrimeprazineMuscarinic acetylcholine receptor M3target
MethotrimeprazineMuscarinic acetylcholine receptor M4target
MethotrimeprazineMuscarinic acetylcholine receptor M5target
MethotrimeprazineAlpha-1A adrenergic receptortarget
MethotrimeprazineAlpha-1B adrenergic receptortarget
MethotrimeprazineAlpha-1D adrenergic receptortarget
MethotrimeprazineCytochrome P450 2D6enzyme
MethotrimeprazineDopamine D2 receptortarget
MethotrimeprazineDopamine D1 receptortarget
MethotrimeprazineDopamine D5 receptortarget
MethotrimeprazineDopamine D4 receptortarget
MethotrimeprazineAlpha-2A adrenergic receptortarget
MethotrimeprazineAlpha-2B adrenergic receptortarget
MethotrimeprazineAlpha-2C adrenergic receptortarget
Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
MethotrimeprazineCytochrome P450 2E1enzyme
DihydrocodeineCytochrome P450 2D6enzyme
DihydrocodeineCytochrome P450 3A4enzyme
Sertindole5-hydroxytryptamine receptor 2Atarget
Sertindole5-hydroxytryptamine receptor 2Ctarget
SertindoleDopamine D2 receptortarget
SertindoleAlpha-1A adrenergic receptortarget
SertindoleAlpha-1B adrenergic receptortarget
SertindoleAlpha-1D adrenergic receptortarget
SertindolePotassium voltage-gated channel subfamily H member 2target
Sertindole5-hydroxytryptamine receptor 6target
SertindoleCytochrome P450 2D6enzyme
SertindoleCytochrome P450 3A4enzyme
TesmilifeneP-glycoprotein 1target
TesmilifeneHistamine H1 receptortarget
TesmilifeneCytochrome P450 3A4enzyme
TesmilifeneCytochrome P450 2D6enzyme
TesmilifeneCytochrome P450 1A1enzyme
RotigotineDopamine D3 receptortarget
RotigotineDopamine D5 receptortarget
RotigotineDopamine D4 receptortarget
RotigotineDopamine D2 receptortarget
Rotigotine5-hydroxytryptamine receptor 1Atarget
RotigotineDopamine D1 receptortarget
RotigotineCytochrome P450 2D6enzyme
RotigotineCytochrome P450 3A4enzyme
RotigotineAlpha-2B adrenergic receptortarget
LisurideDopamine D1 receptortarget
Lisuride5-hydroxytryptamine receptor 1Atarget
LisurideDopamine D2 receptortarget
LisurideAlpha-2A adrenergic receptortarget
LisurideAlpha-2B adrenergic receptortarget
LisurideAlpha-2C adrenergic receptortarget
LisurideDopamine D3 receptortarget
Lisuride5-hydroxytryptamine receptor 1Dtarget
Lisuride5-hydroxytryptamine receptor 2Btarget
Lisuride5-hydroxytryptamine receptor 2Atarget
LisurideDopamine D4 receptortarget
Lisuride5-hydroxytryptamine receptor 2C