Identification
- Generic Name
- Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen
- DrugBank Accession Number
- DB14394
- Background
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen". This defence includes the production of humoral immunity through the development of antibodies (through memory B cells) and of cell-mediated immunity through the production of T-lymphocytes. Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy the virus as there are circulating antibodies that recognize that particular component of the virus that it was previously exposed to.
There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV). Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques. Live vaccines maintain their replicative ability.
- Type
- Biotech
- Groups
- Approved
- Biologic Classification
- Vaccines
Attenuated - Synonyms
- Influenza a Virus A/california/7/2009 (H1n1) Live(attenuated) Antigen
- Influenza a virus a/california/7/2009(h1n1) live(attenuated) antigen
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAbatacept The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Abatacept. Adalimumab The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Adalimumab. Aldesleukin The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Aldesleukin. Alefacept The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Alefacept. Alemtuzumab The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Alemtuzumab. Altretamine The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Altretamine. Amsacrine The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Amsacrine. Anakinra The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Anakinra. Anifrolumab The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Anifrolumab. Antilymphocyte immunoglobulin (horse) The therapeutic efficacy of Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen can be decreased when used in combination with Antilymphocyte immunoglobulin (horse). 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Influenza A H1N1 2009 Monovalent Vaccine Live Intranasal Spray 10000000 1/0.2mL Nasal Med Immune, Llc 2009-10-01 2010-04-13 US 
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image FluMist Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen (10000000 1/0.2mL) + Influenza A virus A/Perth/16/2009 (H3N2) live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 1/0.2mL) Spray Nasal Med Immune, Llc 2011-06-30 2012-07-19 US FluMist Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen (10000000 1/0.2mL) + Influenza A virus A/Perth/16/2009 (H3N2) live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 1/0.2mL) Spray Nasal Med Immune, Llc 2010-07-22 2011-06-30 US FluMist Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen (10000000 1/0.2mL) + Influenza A virus A/Victoria/361/2011 (H3N2) live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen (10000000 1/0.2mL) Spray Nasal Med Immune, Llc 2012-08-01 2013-07-18 US FluMist Quadrivalent Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen (10000000 mg/0.2mL) + Influenza A virus A/Texas/50/2012 (H3N2) live (attenuated) antigen (10000000 mg/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 mg/0.2mL) + Influenza B virus B/Massachusetts/2/2012 live (attenuated) antigen (10000000 mg/0.2mL) Spray Nasal MedImmune, LLC 2014-07-01 2014-07-16 US FluMist Quadrivalent Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen (10000000 1/0.2mL) + Influenza A virus A/Texas/50/2012 (H3N2) live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen (10000000 1/0.2mL) + Influenza B virus B/Massachusetts/2/2012 live (attenuated) antigen (10000000 1/0.2mL) Spray Nasal MedImmune, LLC 2013-07-15 2013-07-24 US
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 22Q2CO717B
- CAS number
- Not Available
References
- General References
- Not Available
- External Links
- Not Available
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Spray Nasal Spray Nasal 10000000 1/0.2mL - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at July 05, 2018 18:02 / Updated at June 12, 2020 16:53