Metastatic Renal Cell Carcinoma ( mRCC)

Also known as: Metastatic Renal Cell Carcinoma (mRCC) / Renal Cell Carcinoma, Metastatic / Renal Cell Carcinoma Metastatic / Metastatic Renal Cell Carcinoma / Metastatic renal cell carcinoma (morphologic abnormality) / Metastatic renal cell carcinoma (disorder)

DrugDrug NameDrug Description
DB00041AldesleukinA recombinant analog of interleukin-2 used to induce an adaptive immune response in the treatment of renal cell carcinoma.
DB00112BevacizumabA monoclonal anti-vascular endothelial growth factor antibody used in combination with antineoplastic agents for the treatment of many types of cancer.
DB00603Medroxyprogesterone acetateA progestin used as a contraceptive and in the treatment of secondary amenorrhea, abnormal uterine bleeding, pain from endometriosis, endometrial and renal carcinomas, paraphilia in males, and GnRH-dependent precocious puberty.
DB09035NivolumabA PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.
DrugDrug NameTargetType
DB00041AldesleukinInterleukin-2 receptor subunit betatarget
DB00041AldesleukinInterleukin-2 receptor subunit alphatarget
DB00041AldesleukinCytokine receptor common subunit gammatarget
DB00041AldesleukinProstaglandin G/H synthase 2enzyme
DB00041AldesleukinCytosolic phospholipase A2enzyme
DB00041AldesleukinCytochrome P450 3A4enzyme
DB00041AldesleukinXanthine dehydrogenase/oxidaseenzyme
DB00041AldesleukinCytochrome P450 2E1enzyme
DB00112BevacizumabVascular endothelial growth factor Atarget
DB00112BevacizumabComplement C1q subcomponent subunit Atarget
DB00112BevacizumabComplement C1q subcomponent subunit Btarget
DB00112BevacizumabComplement C1q subcomponent subunit Ctarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00112BevacizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00603Medroxyprogesterone acetateProgesterone receptortarget
DB00603Medroxyprogesterone acetateEstrogen receptor alphatarget
DB00603Medroxyprogesterone acetateCytochrome P450 3A4enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C8enzyme
DB00603Medroxyprogesterone acetate3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 2C9enzyme
DB00603Medroxyprogesterone acetateCytochrome P450 3A1enzyme
DB00603Medroxyprogesterone acetateSerum albumincarrier
DB00603Medroxyprogesterone acetateP-glycoprotein 1target
DB00603Medroxyprogesterone acetateGABA(A) Receptortarget
DB00603Medroxyprogesterone acetateP-glycoprotein 1transporter
DB09035NivolumabProgrammed cell death protein 1target
DrugDrug NamePhaseStatusCount
DB08947Iopamidol0Completed1
DB05182AS14091Completed1
DB12001Abemaciclib1Active Not Recruiting1
DB08885Aflibercept1Recruiting1
DB00062Albumin human1Recruiting1
DB00041Aldesleukin1Recruiting1
DB11595Atezolizumab1Recruiting1
DB15463Belzutifan1Active Not Recruiting1
DB00112Bevacizumab1Completed2
DB08875Cabozantinib1Active Not Recruiting1
DB08875Cabozantinib1Recruiting3
DB01373Calcium1Recruiting1
DB04690Camptothecin1Recruiting1
DB01101Capecitabine1Recruiting1
DB00958Carboplatin1Recruiting1
DB00531Cyclophosphamide1Recruiting3
DB00531Cyclophosphamide1Withdrawn1
DB11651Dactolisib1Completed1
DB00694Daunorubicin1Recruiting1
DB00997Doxorubicin1Recruiting1
DB08871Eribulin1Recruiting1
DB01590Everolimus1Completed2
DB01073Fludarabine1Recruiting1
DB00544Fluorouracil1Recruiting1
DB14865Human interleukin-21Withdrawn1
DB06186Ipilimumab1Active Not Recruiting1
DB06186Ipilimumab1Recruiting2
DB00762Irinotecan1Recruiting1
DB00650Leucovorin1Recruiting1
DB11596Levoleucovorin1Recruiting1
DB09035Nivolumab1Active Not Recruiting1
DB09035Nivolumab1Recruiting5
DB09035Nivolumab1Terminated1
DB09074Olaparib1Recruiting1
DB09330Osimertinib1Recruiting1
DB00526Oxaliplatin1Recruiting1
DB01229Paclitaxel1Recruiting2
DB06589Pazopanib1Completed2
DB09037Pembrolizumab1Recruiting5
DB00642Pemetrexed1Recruiting1
DB08913Radium Ra 223 dichloride1Completed1
DB09566Radium Ra 223 dichloride1Completed1
DB12813Radium Ra-2231Completed1
DB00020Sargramostim1Recruiting1
DB11942Selinexor1Recruiting1
DB00398Sorafenib1Completed1
DB01268Sunitinib1Active Not Recruiting1
DB01268Sunitinib1Completed1
DB01030Topotecan1Recruiting1
DB00041Aldesleukin1 / 2Completed1
DB06626Axitinib1 / 2Recruiting1
DB11105Benzalkonium1 / 2Terminated1
DB08875Cabozantinib1 / 2Active Not Recruiting1
DB00002Cetuximab1 / 2Completed1
DB00531Cyclophosphamide1 / 2Recruiting1
DB01248Docetaxel1 / 2Completed1
DB01590Everolimus1 / 2Completed2
DB05304Girentuximab1 / 2Completed1
DB01611Hydroxychloroquine1 / 2Completed1
DB09053Ibrutinib1 / 2Completed1
DB09570Ixazomib1 / 2Terminated1
DB09078Lenvatinib1 / 2Completed1
DB09035Nivolumab1 / 2Withdrawn1
DB13048PAC-11 / 2Withdrawn1
DB01229Paclitaxel1 / 2Completed1
DB09037Pembrolizumab1 / 2Active Not Recruiting2
DB09037Pembrolizumab1 / 2Completed1
DB09037Pembrolizumab1 / 2Recruiting1
DB11760Talazoparib1 / 2Recruiting1
DB023422-Methoxyestradiol2Completed1
DB04998AGRO1002Unknown Status1
DB00945Acetylsalicylic acid2Active Not Recruiting1
DB00640Adenosine2Recruiting1
DB08885Aflibercept2Completed1
DB00041Aldesleukin2Completed1
DB00041Aldesleukin2Recruiting1
DB00041Aldesleukin2Unknown Status1
DB11595Atezolizumab2Terminated1
DB11945Avelumab2Not Yet Recruiting1
DB11945Avelumab2Recruiting1
DB06626Axitinib2Completed3
DB06626Axitinib2Not Yet Recruiting1
DB06626Axitinib2Recruiting1
DB06626Axitinib2Terminated1
DB00112Bevacizumab2Completed3
DB00112Bevacizumab2Terminated1
DB00112Bevacizumab2Unknown Status2
DB00188Bortezomib2Terminated1
DB16741Bortezomib D-mannitol2Terminated1
DB08875Cabozantinib2Active Not Recruiting1
DB08875Cabozantinib2Completed2
DB08875Cabozantinib2Not Yet Recruiting1
DB08875Cabozantinib2Recruiting2
DB01101Capecitabine2Completed1
DB14917Ceralasertib2Recruiting1
DB00694Daunorubicin2Recruiting1
DB01262Decitabine2Recruiting1
DB00997Doxorubicin2Completed2
DB00997Doxorubicin2Recruiting1
DB06486Enzastaurin2Completed1
DB01590Everolimus2Completed3
DB01590Everolimus2Terminated1
DB00099Filgrastim2Completed1
DB00441Gemcitabine2Completed2
DB00441Gemcitabine2Recruiting1
DB14865Human interleukin-22Terminated1
DB00034Interferon alfa-2a2Completed2
DB00105Interferon alfa-2b2Unknown Status1
DB06186Ipilimumab2Active Not Recruiting1
DB06186Ipilimumab2Not Yet Recruiting1
DB06186Ipilimumab2Recruiting2
DB06186Ipilimumab2Withdrawn1
DB09570Ixazomib2Recruiting1
DB09078Lenvatinib2Not Yet Recruiting1
DB09035Nivolumab2Active Not Recruiting2
DB09035Nivolumab2Completed1
DB09035Nivolumab2Not Yet Recruiting1
DB09035Nivolumab2Recruiting4
DB09035Nivolumab2Terminated2
DB09035Nivolumab2Withdrawn1
DB09074Olaparib2Recruiting2
DB00526Oxaliplatin2Recruiting1
DB14769Pamiparib2Recruiting1
DB06589Pazopanib2Completed5
DB06589Pazopanib2Terminated2
DB06589Pazopanib2Unknown Status1
DB00019Pegfilgrastim2Completed1
DB09037Pembrolizumab2Not Yet Recruiting1
DB09037Pembrolizumab2Recruiting1
DB09037Pembrolizumab2Terminated1
DB05578Ramucirumab2Completed1
DB15073Ribose2Recruiting1
DB14765Rivoceranib2Unknown Status1
DB00398Sorafenib2Active Not Recruiting1
DB00398Sorafenib2Completed3
DB00398Sorafenib2Terminated3
DB00398Sorafenib2Unknown Status1
DB01268Sunitinib2Active Not Recruiting2
DB01268Sunitinib2Completed8
DB01268Sunitinib2Terminated4
DB01268Sunitinib2Unknown Status2
DB11760Talazoparib2Recruiting1
DB14227Technetium Tc-99m2Completed1
DB15232Telaglenastat2Completed1
DB00853Temozolomide2Recruiting1
DB06287Temsirolimus2Active Not Recruiting1
DB06287Temsirolimus2Completed1
DB13946Testosterone undecanoate2Completed1
DB11800Tivozanib2Terminated1
DB15140Bempegaldesleukin3Active Not Recruiting1
DB08875Cabozantinib3Active Not Recruiting1
DB00531Cyclophosphamide3Completed1
DB06643Denosumab3Terminated1
DB05928Dovitinib3Completed1
DB01590Everolimus3Completed1
DB14865Human interleukin-23Completed1
DB05258Interferon alfa3Completed1
DB06186Ipilimumab3Active Not Recruiting1
DB00603Medroxyprogesterone acetate3Completed1
DB01043Memantine3Recruiting1
DB09035Nivolumab3Active Not Recruiting3
DB00020Sargramostim3Completed1
DB00398Sorafenib3Completed2
DB00398Sorafenib3Unknown Status1
DB01268Sunitinib3Active Not Recruiting2
DB01268Sunitinib3Completed1
DB01268Sunitinib3Terminated1
DB01268Sunitinib3Unknown Status1
DB00399Zoledronic acid3Terminated1
DB00041Aldesleukin4Completed1
DB01590Everolimus4Completed3
DB01268Sunitinib4Terminated1
DB11595AtezolizumabNot AvailableNot Yet Recruiting1
DB11945AvelumabNot AvailableNot Yet Recruiting1
DB06626AxitinibNot AvailableNot Yet Recruiting1
DB00112BevacizumabNot AvailableNot Yet Recruiting1
DB08875CabozantinibNot AvailableNot Yet Recruiting1
DB09526HydroquinoneNot AvailableTerminated1
DB06186IpilimumabNot AvailableNot Yet Recruiting1
DB09078LenvatinibNot AvailableNot Yet Recruiting1
DB09035NivolumabNot AvailableNot Yet Recruiting1
DB06589PazopanibNot AvailableCompleted2
DB09037PembrolizumabNot AvailableNot Yet Recruiting1
DB01268SunitinibNot AvailableCompleted6
DB01268SunitinibNot AvailableRecruiting1
DB01268SunitinibNot AvailableTerminated2