Vidofludimus

DB15446InvestigationalSmall molecule

Vidofludimus is under investigation in clinical trial NCT03722576 (Vidofludimus Calcium for Primary Sclerosing Cholangitis).

Mechanism: Pharmacologically active on Dihydroorotate dehydrogenase (quinone), mitochondrial
Curator reviewed
Formula / weight: C₂₀H₁₈FNO₄ · 355.365 g/mol (avg)
Code names: IMU-838

Resolves to

Compound

Structure

InChIKeyXPRDUGXOWVXZLL-UHFFFAOYSA-NSMILESCOC1=CC(=CC=C1)C1=CC=C(NC(=O)C2=C(CCC2)C(O)=O)C(F)=C1

Targets

What you can answer from here — as of August 29, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

8+ReferencesStructured and connected to the statements they support

Which drugs share a target with Vidofludimus, and which of those have an active Phase 3 trial?

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