This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Pitofenone is a medication used in the treatment of spastic pain caused by menstrual cramps, the digestive system, and the urinary tract.

Generic Name
Pitofenone
DrugBank Accession Number
DB15947
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 367.445
Monoisotopic: 367.178358289
Chemical Formula
C22H25NO4
Synonyms
  • Pitofenona
  • Pitofenone
  • Pitofenonum

Pharmacology

Indication

Not Available

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Product Ingredients
IngredientUNIICASInChI Key
Pitofenone hydrochlorideHE1ZA4ZBEX1248-42-6ZRFIFDFEDPJBII-UHFFFAOYSA-N
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
จีนาลแกนPitofenone (5 MG) + Fenpiverinium (0.1 MG)Tabletบริษัท พอนด์ เคมีคอล จำกัด2015-11-192020-09-01Thailand flag
ฟาแกนPitofenone (5 MG) + Fenpiverinium (0.1 MG)Tabletบริษัท เอเชี่ยนยูเนี่ยนแล็บบอราตอรี่ จำกัด จำกัด1989-01-23Not applicableThailand flag
ฟิลิแกนเม็ดPitofenone (5 MG) + Fenpiverinium (0.1 MG)Tabletบริษัท วี แอนด์ พี ลาบอราตอรี่ จำกัด จำกัด1990-04-11Not applicableThailand flag

Categories

ATC Codes
A03DA02 — Pitofenone and analgesics
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
M09N8K7YJY
CAS number
54063-52-4
InChI Key
NZHMAQSCHUSSSJ-UHFFFAOYSA-N
InChI
InChI=1S/C22H25NO4/c1-26-22(25)20-8-4-3-7-19(20)21(24)17-9-11-18(12-10-17)27-16-15-23-13-5-2-6-14-23/h3-4,7-12H,2,5-6,13-16H2,1H3
IUPAC Name
methyl 2-{4-[2-(piperidin-1-yl)ethoxy]benzoyl}benzoate
SMILES
COC(=O)C1=CC=CC=C1C(=O)C1=CC=C(OCCN2CCCCC2)C=C1

References

General References
  1. FDA Thailand: Genalgan (Fenpiverinium, Pitofenone) Oral Tablet [Link]
ChemSpider
108096
ChEBI
135547
ChEMBL
CHEMBL2104821
ZINC
ZINC000000538207
Wikipedia
Pitofenone

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0128 mg/mLALOGPS
logP3.94ALOGPS
logP4.15ChemAxon
logS-4.5ALOGPS
pKa (Strongest Basic)8.63ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area55.84 Å2ChemAxon
Rotatable Bond Count8ChemAxon
Refractivity105.28 m3·mol-1ChemAxon
Polarizability41.18 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleYesChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at November 26, 2020 14:35 / Updated at May 07, 2021 21:09