Drugs for Functional Gastrointestinal Disorders
- Drugs for Functional Gastrointestinal Disorders
- Accession Number
- ATC Classification
Drug Drug Description Oxyphenonium For the treatment of visceral spasms Oxyphencyclimine A drug used to treat smooth muscle spasticity. Hyoscyamine An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. Tridihexethyl Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Cisapride A medication used to treat heartburn associated with GERD. Homatropine methylbromide A muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Clidinium A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Dicyclomine An antimuscarinic agent used to treat IBS. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Alosetron A 5-HT3 antagonist used to treat diarrhea-predominant IBS. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Papaverine An alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms". Domperidone A dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting. Metoclopramide An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying. Alizapride A dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies. Alverine A smooth muscle relaxant used to relieve abdominal pain associated with gastrointestinal conditions like heartburn, flatulence, and Irritable Bowel Syndrome. Isopropamide A long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions. Mepenzolate A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. Cilansetron For the treatment of symptoms associated with irritable bowel syndrome. Itopride An acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting. Isometheptene A sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole. Drotaverine A phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms. Hexocyclium The World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea. Fentonium Fentonium is an atropine derivative. Bromopride A substituted benzamide, closely related to metoclopramide, used as an antiemetic. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Pinaverium A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract. Cimetropium Cimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which... Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Methscopolamine Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The... Moxaverine Moxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow. Mebeverine An antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses. Phloroglucinol A spasmolytic agent to treat colic, as well as spastic pain of the digestive and biliary tracts. Fenoverine A phenothiazine based anti-spasmodic agent indicated in the treatment of irritable bowel syndrome. Tiropramide A medication indicated in the treatment of spastic pain of the gastrointestinal system. Prifinium Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome . Idanpramine Not Annotated Trepibutone Not Annotated Piperidolate Not Annotated Trimethyldiphenylpropylamine Not Annotated Benzilone Not Annotated Difemerine Not Annotated Fenpiprane Not Annotated Diisopromine Not Annotated Valethamate An anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Poldine Not Annotated Clebopride A dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy. Nicofetamide Not Annotated Bevonium Not Annotated Rociverine An antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms. Tiemonium iodide Not Annotated Dimethylaminopropionylphenothiazine Not Annotated Dihexyverine Not Annotated Penthienate Not Annotated Diphemanil Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). Camylofin Not Annotated Fenpiverinium An anticholinergic agent indicated in the treatment of smooth muscle spasms. Emetonium iodide Not Annotated Chlorbenzoxamine Not Annotated Proxazole Not Annotated Methylatropine Not Annotated Caroverine A calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus. Pipenzolate An antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia. Timepidium Not Annotated Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Emepronium Not Annotated Cinitapride A benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying. Mosapride A prokinetic 5-HT4 receptor agonist used to stimulate gastric motility. Pitofenone A medication used in the treatment of spastic pain caused by menstrual cramps, the digestive system, and the urinary tract. Peppermint oil An ingredient used in a variety of natural health products and is not an approved medication. Acotiamide Acotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
- Drugs & Drug Targets