Accession Number

Heterocyclic compounds where the ring system is composed of three CARBON atoms, a SULFUR and NITROGEN atoms.

DrugDrug Description
ThiamineA vitamin used to correct vitamin B1 deficiency.
TimololA non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma.
PramipexoleA non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS).
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
MethazolamideA carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
RiluzoleA glutamate antagonist used to treat amyotrophic lateral sclerosis.
AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
LevamisoleLevamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
PioglitazoneA thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus.
FebuxostatA xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol.
ClomethiazoleInvestigated for use/treatment in strokes.
LurasidoneAn atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
CobicistatA CYP3A inhibitor used to increase the systemic exposure of atazanavir or darunavir in combination with other antiretroviral agents in the treatment of HIV-1 infection.
DithiazanineDithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was...
SaccharinA non-nutritive artificial sweetener for sweetening foods and drinks.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
TetramisoleAn anthelmintic indicated to treat hookworm infections.
EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
DasatinibA tyrosine kinase inhibitor used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia.
NiridazoleNot Annotated
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
CocarboxylaseThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
Latrunculin ALatrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic...
3-(2-Benzothiazolylthio)-1-Propanesulfonic AcidNot Available
RWJ-51084Not Available
FilanesibInvestigated for use/treatment in cancer/tumors (unspecified).
SulfathiazoleSulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideNot Available
CP-94707Not Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideNot Available
Latrunculin BLatrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge Latrunculia magnifica.
ZopolrestatNot Available
LetosteineLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
FursultiamineCompound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
Flutemetamol (18F)A radiopharmaceutical diagnostic agent used during Positron Emission Tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients to diagnose the causes of cognitive impairment.
LobeglitazoneLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use...
NetoglitazoneNetoglitazone (MCC-555) is a hypoglycemic agent.
RivoglitazoneRivoglitazone (INN) is a thiazolidinedione undergoing research for use in the treatment of type 2 diabetes. It is being developed by Daiichi Sankyo Co.
CiglitazoneDeveloped by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. Ciglitazone was never used as a medication, but it sparked interest in...
PidotimodA synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.
2-mercaptobenzothiazoleNot Annotated
MitoglitazoneMitoglitazone has been used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
BenfotiamineA derivative of thiamine thought to be useful in the management of diabetic neuropathy, although evidence is lacking.
LitronesibLitronesib has been used in trials studying the treatment of Solid Tumors, Ovarian Cancer, Gastric Cancer, Prostate Cancer, and Acute Leukaemia, among others.
EfatutazoneEfatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
2,4-thiazolidinedioneThiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.
TeneligliptinTeneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.
TideglusibTideglusib was initially formulated for the treatment of Alzheimer and progressive supranuclear palsy. The raising interest for the use of tideglusib comes from the significant upregulation of GSK-3 in the...
TozadenantTozadenant has been investigated for the basic science of Cocaine Dependence.
Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
5-amino-1,3,4-thiadiazole-2-thiolATT has been investigated in Pulmonary Tuberculosis.
SagopiloneSagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is...
BalaglitazoneBalaglitazone has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
QuizartinibA FLT3 inhibitor used in combination with cytarabine and anthracycline to treat acute myeloid leukemia with FLT3 internal tandem duplication
TalarozoleTalarozole has been investigated for the treatment of Psoriasis and Cutaneous Inflammation.
PiprozolinNot Annotated
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
SulbutiamineA thiamine derivative indicated in the treatment of asthenia.
SuccinylsulfathiazoleNot Annotated
DarglitazoneNot Annotated
EnglitazoneEnglitazone is a hypoglycemic agent.
ThiohexamThiohexam is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years...
2,2'-Dibenzothiazyl disulfide2,2'-Dibenzothiazyl disulfide is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6...
MorpholinylmercaptobenzothiazoleNot Annotated
LanifibranorLanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
PadsevonilPadsevonil is under investigation in clinical trial NCT03695094 (A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil).
LeriglitazoneLeriglitazone is under investigation in clinical trial NCT03917225 (A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients).
BMS-791826BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).
FlutemetamolFlutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
DexpramipexoleDexpramipexole is under investigation in clinical trial NCT01511029 (Study to Evaluate the QTC Interval in Healthy Volunteers Dosed With Dexpramipexole (QTC = Electrocardiogram (ECG) Interval Measured From the Onset of...
TelaglenastatTelaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors).
EpalrestatEpalrestat is under investigation in clinical trial NCT03244358 (Evaluation of Epalrestat in Metastatic Triple-negative Breast Cancer).
XanomelineXanomeline is under investigation in clinical trial NCT02831231 (Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium).
SAR-125844SAR-125844 is under investigation in clinical trial NCT01391533 (Study of SAR125844 Single Agent Administered as Slow Intravenous Infusion in Adult Patients With Advanced Malignant Solid Tumors).
TMC-310911TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections....
HalicinNot Annotated
FezolinetantA non-hormonal drug used to treat moderate to severe vasomotor symptoms due to menopause
Thiamine disulfideA B-vitamin indicated to treat neurological conditions caused by B vitamin deficiency.
MonophosphothiamineA B vitamin for supplementation to treat macrocytic anemia, and other conditions caused by B vitamin deficiencies.
AzemiglitazoneAzemiglitazone is under investigation in clinical trial NCT01280695 (A Randomized, Double-blind, Comparator- and Placebo-controlled, Multiple-dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in...
DotinuradDotinurad is under investigation in clinical trial NCT03372200 (Febuxostat-controlled, Double-blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout).
EbopiprantEbopiprant is under investigation in clinical trial NCT03369262 (Poc Study of OBE022 in Threatened Preterm Labour).
TropifexorTropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients).
BenzoyloxymethylthiamineNot Annotated
MM3122Not Annotated
S-49076Not Annotated
BLZ-945Not Annotated
PidnarulexNot Annotated
BentamapimodNot Annotated
AF-710BNot Annotated
MRK-003MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
BioymifiBioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic. Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis,...
AT-001AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
BMS-986141BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Drugs & Drug Targets
ThiamineThiamin pyrophosphokinase 1target
ThiamineSolute carrier family 22 member 2transporter
ThiamineSolute carrier family 22 member 1transporter
ThiamineSolute carrier family 22 member 5transporter
ThiamineCytochrome P450 4B1enzyme
ThiamineThiamine transporter 1transporter
ThiamineThiamine transporter 2transporter
ThiamineThiamin pyrophosphokinase 1enzyme
ThiamineEctonucleoside triphosphate diphosphohydrolase 5enzyme
ThiamineSerum albumincarrier
TimololBeta-1 adrenergic receptortarget
TimololBeta-2 adrenergic receptortarget
TimololCytochrome P450 2D6enzyme
TimololP-glycoprotein 1transporter
TimololCytochrome P450 2C19enzyme
PramipexoleDopamine D3 receptortarget
PramipexoleDopamine D4 receptortarget
PramipexoleDopamine D2 receptortarget
Pramipexole5-hydroxytryptamine receptor 1Atarget
PramipexoleAlpha-2A adrenergic receptortarget
PramipexoleSolute carrier family 22 member 2transporter
PramipexoleSolute carrier family 22 member 1transporter
PramipexoleSolute carrier family 22 member 3transporter
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
SulfamethizoleDihydropteroate synthasetarget
SulfamethizoleSerum albumincarrier
SulfamethizoleCytochrome P450 2C9enzyme
NizatidineHistamine H2 receptortarget
NizatidineP-glycoprotein 1transporter
MethazolamideCarbonic anhydrase 1target
MethazolamideSolute carrier family 22 member 6transporter
MethazolamideCarbonic anhydrase 4target
MethazolamideCarbonic anhydrase 2target
MethazolamideCarbonic anhydrase 7target
MethazolamideCarbonic anhydrase 3target
ThiabendazoleFumarate reductase flavoprotein subunittarget
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleCytochrome P450 1A1enzyme
RiluzoleSodium channel protein type 5 subunit alphatarget
RiluzoleCytochrome P450 1A2enzyme
RiluzoleCystine/glutamate transportertarget
RiluzoleATP-binding cassette sub-family G member 2transporter
RiluzoleCytochrome P450 1A1enzyme
AcetazolamideCarbonic anhydrase 1target
AcetazolamideCarbonic anhydrase 14target
AcetazolamideSolute carrier family 22 member 6transporter
AcetazolamideCarbonic anhydrase 2target
AcetazolamideCarbonic anhydrase 3target
AcetazolamideCarbonic anhydrase 4target
AcetazolamideCytochrome P450 3A4enzyme
AcetazolamideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 12target
LevamisoleNeuronal acetylcholine receptor subunit alpha-3target
LevamisoleAlkaline phosphatase, germ cell typetarget
LevamisoleAcetylcholine receptor subunit alpha-type unc-38target
LevamisoleAcetylcholine receptor subunit alpha-type unc-63target
LevamisoleAcetylcholine receptor subunit beta-type lev-1target
LevamisoleAcetylcholine receptor subunit beta-type unc-29target
FamotidineHistamine H2 receptortarget
FamotidineSolute carrier family 22 member 2transporter
FamotidineSolute carrier family 22 member 8transporter
FamotidineMultidrug and toxin extrusion protein 1transporter
FamotidineCytochrome P450 1A2enzyme
FamotidineSolute carrier family 22 member 6transporter
PioglitazonePeroxisome proliferator-activated receptor gammatarget
PioglitazoneCytochrome P450 2C8enzyme
PioglitazoneCytochrome P450 3A4enzyme
PioglitazoneSolute carrier organic anion transporter family member 1B3transporter
PioglitazoneSolute carrier organic anion transporter family member 1B1transporter
PioglitazoneAmine oxidase [flavin-containing] Btarget
PioglitazoneSerum albumincarrier
PioglitazoneCytochrome P450 1A1enzyme
FebuxostatSerum albumincarrier
FebuxostatXanthine dehydrogenase/oxidasetarget
FebuxostatUDP-glucuronosyltransferase 1-1enzyme
FebuxostatUDP-glucuronosyltransferase 1-3enzyme
FebuxostatUDP-glucuronosyltransferase 1-9enzyme
FebuxostatUDP-glucuronosyltransferase 2B7enzyme
FebuxostatCytochrome P450 1A2enzyme
FebuxostatCytochrome P450 2C8enzyme
FebuxostatCytochrome P450 2C9enzyme
FebuxostatATP-binding cassette sub-family G member 2transporter
ClomethiazoleGamma-aminobutyric acid receptor subunit alpha-1target
ClomethiazoleCytochrome P450 2A6enzyme
ClomethiazoleCytochrome P450 2B6enzyme
ClomethiazoleCytochrome P450 2C19enzyme
ClomethiazoleCytochrome P450 3A4enzyme
LurasidoneCytochrome P450 3A4enzyme
LurasidoneDopamine D2 receptortarget
Lurasidone5-hydroxytryptamine receptor 2Atarget
Lurasidone5-hydroxytryptamine receptor 7target
Lurasidone5-hydroxytryptamine receptor 1Atarget
LurasidoneAlpha-2C adrenergic receptortarget
LurasidoneAlpha-2A adrenergic receptortarget
CobicistatCytochrome P450 2D6enzyme
CobicistatP-glycoprotein 1transporter
CobicistatATP-binding cassette sub-family G member 2transporter
CobicistatCytochrome P450 3A5enzyme
CobicistatCytochrome P450 3A7enzyme
CobicistatSolute carrier organic anion transporter family member 1B1transporter
CobicistatSolute carrier organic anion transporter family member 1B3transporter
CobicistatCytochrome P450 3A4target
CobicistatCytochrome P450 3A4enzyme
CobicistatCytochrome P450 3A5target
CobicistatCytochrome P450 3A7target
SaccharinCarbonic anhydrase 3target
MeloxicamProstaglandin G/H synthase 2target
MeloxicamCytochrome P450 2C9enzyme
MeloxicamProstaglandin G/H synthase 1target
MeloxicamCytochrome P450 3A4enzyme
MeloxicamMultidrug resistance-associated protein 4transporter
Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MeloxicamCytochrome P450 2C8enzyme
MeloxicamSerum albumincarrier
MeloxicamHuman vesicular glutamate transporterstransporter
EthoxzolamideCarbonic anhydrase 1target
EthoxzolamideSolute carrier family 22 member 6transporter
EthoxzolamideCarbonic anhydrase 2target
EthoxzolamideCarbonic anhydrase 4target
EthoxzolamideCarbonic anhydrase 7target
EthoxzolamideCarbonic anhydrase 3target
DasatinibTyrosine-protein kinase ABL1target
DasatinibTyrosine-protein kinase ABL2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
TroglitazonePeroxisome proliferator-activated receptor gammatarget
TroglitazoneLong-chain-fatty-acid--CoA ligase 4target
TroglitazonePlasminogen activator inhibitor 1target
TroglitazoneEquilibrative nucleoside transporter 1target
TroglitazoneCytochrome P450 3A4enzyme
TroglitazoneCytochrome P450 2C19enzyme
TroglitazoneUDP-glucuronosyltransferase 1-1enzyme
TroglitazoneCytochrome P450 2C8enzyme
TroglitazoneBile salt export pumptransporter
TroglitazoneSolute carrier organic anion transporter family member 1B1transporter
TroglitazoneEstrogen-related receptor gammatarget
TroglitazoneSteroid hormone receptor ERR1target
TroglitazoneCytochrome P450 19A1enzyme
TroglitazoneCytochrome P450 1A1enzyme
TroglitazoneCytochrome P450 2B6enzyme
TroglitazoneCytochrome P450 2C9enzyme
TroglitazoneCytochrome P450 3A5enzyme
TroglitazoneCytochrome P450 3A7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-3enzyme
TroglitazoneUDP-glucuronosyltransferase 1-4enzyme
TroglitazoneUDP-glucuronosyltransferase 1-6enzyme
TroglitazoneUDP-glucuronosyltransferase 1-7enzyme
TroglitazoneUDP-glucuronosyltransferase 1-8enzyme
TroglitazoneUDP-glucuronosyltransferase 1-9enzyme
TroglitazoneUDP-glucuronosyltransferase 1-10enzyme
TroglitazoneUDP-glucuronosyltransferase 2B7enzyme
TroglitazoneUDP-glucuronosyltransferase 2B15enzyme
TroglitazonePeroxisome proliferator-activated receptor deltatarget
TroglitazonePeroxisome proliferator-activated receptor alphatarget
TroglitazoneGlutathione S-transferase Ptarget
RosiglitazonePeroxisome proliferator-activated receptor gammatarget
RosiglitazoneCytochrome P450 2C8enzyme
RosiglitazoneCytochrome P450 2C9enzyme
RosiglitazoneLong-chain-fatty-acid--CoA ligase 4target
RosiglitazoneSolute carrier organic anion transporter family member 1B1transporter
RosiglitazoneProstaglandin G/H synthase 1enzyme
RosiglitazoneCytochrome P450 1A2enzyme
RosiglitazoneCytochrome P450 2D6enzyme
RosiglitazoneSerum albumincarrier
RosiglitazonePeroxisome proliferator-activated receptor alphatarget
RosiglitazonePeroxisome proliferator-activated receptor deltatarget
RosiglitazoneRetinoic acid receptor RXR-alphatarget
RosiglitazoneRetinoic acid receptor RXR-betatarget
RosiglitazoneRetinoic acid receptor RXR-gammatarget
RosiglitazoneCytochrome P450 3A4enzyme
RosiglitazoneBile salt export pumptransporter
RosiglitazoneCytochrome P450 2B6enzyme
RosiglitazoneCytochrome P450 2E1enzyme
RosiglitazoneSodium/bile acid cotransportertransporter
CocarboxylaseAcetolactate synthase, catabolictarget
CocarboxylasePyruvate dehydrogenase E1 componenttarget
CocarboxylasePyruvate-flavodoxin oxidoreductasetarget
CocarboxylaseIndole-3-pyruvate decarboxylasetarget
CocarboxylaseCarboxyethylarginine synthasetarget
CocarboxylaseTransketolase 1target
CocarboxylaseBenzoylformate decarboxylaseenzyme
CocarboxylasePyruvate oxidaseenzyme
Latrunculin AActin, alpha skeletal muscletarget
Latrunculin AGelsolintarget
Latrunculin AIota toxin component Iatarget
3-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerase, glycosomaltarget
3-(2-Benzothiazolylthio)-1-Propanesulfonic AcidTriosephosphate isomerasetarget
FilanesibKinesin-like protein KIF11target
SulfathiazoleDihydropteroate synthetasetarget
SulfathiazoleCytochrome P450 19A1enzyme
CP-94707Gag-Pol polyproteintarget
Latrunculin BActin, alpha skeletal muscletarget
Latrunculin BMKL/myocardin-like protein 1target
Latrunculin BProtein spire homolog 2target
ZopolrestatAldo-keto reductase family 1 member B10target
ZopolrestatAldose reductasetarget
Flutemetamol (18F)Amyloid beta A4 proteintarget
LobeglitazoneSolute carrier organic anion transporter family member 1B1transporter
LobeglitazoneSolute carrier organic anion transporter family member 3A1transporter
LobeglitazoneP-glycoprotein 1transporter
LobeglitazoneCytochrome P450 1A2enzyme
LobeglitazoneCytochrome P450 2C9enzyme
LobeglitazoneCytochrome P450 2C19enzyme
LobeglitazonePeroxisome proliferator-activated receptor gammatarget
LobeglitazoneCytochrome P450 3A4enzyme
LobeglitazoneCytochrome P450 2C8enzyme
NetoglitazoneCytochrome P450 3A4enzyme
NetoglitazoneCytochrome P450 2C8enzyme
RivoglitazoneCytochrome P450 3A4enzyme
RivoglitazoneCytochrome P450 2C8enzyme
CiglitazonePeroxisome proliferator-activated receptor gammatarget
CiglitazoneCytochrome P450 3A4enzyme
CiglitazoneCytochrome P450 2C8enzyme
2-mercaptobenzothiazoleThyroid peroxidasetarget
TideglusibGlycogen synthase kinase-3 betatarget
SagopiloneCytochrome P450 3A4enzyme
BalaglitazoneCytochrome P450 3A4enzyme
BalaglitazoneCytochrome P450 2C8enzyme
QuizartinibReceptor-type tyrosine-protein kinase FLT3target
QuizartinibCytochrome P450 3A4enzyme
QuizartinibCytochrome P450 3A5enzyme
QuizartinibUDP-glucuronosyltransferase 1-1enzyme
QuizartinibP-glycoprotein 1transporter
QuizartinibATP-binding cassette sub-family G member 2transporter
QuizartinibSerum albumincarrier
QuizartinibCytochrome P450 3A7enzyme
TalarozoleCytochrome P450 26A1target
DarglitazonePeroxisome proliferator-activated receptor gammatarget
TMC-310911HIV-1 proteasetarget
Halicinc-Jun N-terminal kinasestarget
FezolinetantCytochrome P450 1A2enzyme
FezolinetantCytochrome P450 2C9enzyme
FezolinetantCytochrome P450 2C19enzyme
FezolinetantNeuromedin-K receptortarget
TropifexorBile acid receptortarget
MM3122Transmembrane protease serine 2target
BioymifiTumor necrosis factor receptor superfamily member 10Btarget